ATE503843T1 - Gesamt-chromosom analyse von protein-dns wechselwirkungen - Google Patents
Gesamt-chromosom analyse von protein-dns wechselwirkungenInfo
- Publication number
- ATE503843T1 ATE503843T1 AT00959909T AT00959909T ATE503843T1 AT E503843 T1 ATE503843 T1 AT E503843T1 AT 00959909 T AT00959909 T AT 00959909T AT 00959909 T AT00959909 T AT 00959909T AT E503843 T1 ATE503843 T1 AT E503843T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- cell
- genomic dna
- dna
- region
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15197299P | 1999-09-01 | 1999-09-01 | |
PCT/US2000/024358 WO2001016378A2 (en) | 1999-09-01 | 2000-09-01 | Chromosome-wide analysis of protein-dna interactions |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE503843T1 true ATE503843T1 (de) | 2011-04-15 |
Family
ID=22541045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00959909T ATE503843T1 (de) | 1999-09-01 | 2000-09-01 | Gesamt-chromosom analyse von protein-dns wechselwirkungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US6410243B1 (de) |
EP (1) | EP1220949B1 (de) |
JP (1) | JP2003508066A (de) |
AT (1) | ATE503843T1 (de) |
CA (1) | CA2383928A1 (de) |
DE (2) | DE60045796D1 (de) |
WO (1) | WO2001016378A2 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7470507B2 (en) | 1999-09-01 | 2008-12-30 | Whitehead Institute For Biomedical Research | Genome-wide location and function of DNA binding proteins |
US20030087231A1 (en) * | 2000-05-19 | 2003-05-08 | Albertson Donna G. | Methods and compositions for preparation of a polynucleotide array |
AU2001292718A1 (en) * | 2000-09-12 | 2002-03-26 | Transgenetics Incorporated | Microarrayed organization of transcription factor target genes |
DE10056899A1 (de) * | 2000-11-16 | 2002-05-29 | Aventis Pharma Gmbh | Promotor zur funktionellen Charakterisierung von G-Protein gekoppelten Rezeptoren in der Hefe Saccharomyces cerevisiae |
WO2002059371A2 (en) * | 2000-12-21 | 2002-08-01 | Whitehead Institute For Biomedical Research | Genome-wide location and function of dna binding proteins |
US20040058356A1 (en) * | 2001-03-01 | 2004-03-25 | Warren Mary E. | Methods for global profiling gene regulatory element activity |
CA2498928A1 (en) * | 2002-09-12 | 2004-03-25 | Massachusetts Institute Of Technology | Rb pathway and chromatin remodeling genes that antagonize let-60 ras signaling |
US20060099713A1 (en) * | 2002-10-01 | 2006-05-11 | Buck Institute | Targeted-assisted iterative screening (tais):a novel screening format for large molecular repertoires |
US20040161779A1 (en) * | 2002-11-12 | 2004-08-19 | Affymetrix, Inc. | Methods, compositions and computer software products for interrogating sequence variations in functional genomic regions |
US20040115794A1 (en) * | 2002-12-12 | 2004-06-17 | Affymetrix, Inc. | Methods for detecting transcriptional factor binding sites |
US7750908B2 (en) * | 2003-04-04 | 2010-07-06 | Agilent Technologies, Inc. | Focus plus context viewing and manipulation of large collections of graphs |
CN1816636A (zh) * | 2003-07-03 | 2006-08-09 | 加利福尼亚大学董事会 | 功能性dna元件和细胞蛋白的基因组作图 |
US8222005B2 (en) * | 2003-09-17 | 2012-07-17 | Agency For Science, Technology And Research | Method for gene identification signature (GIS) analysis |
DE112004002318T5 (de) * | 2003-11-26 | 2007-01-18 | Whitehead Institute For Biomedical Research, Cambridge | Transkriptionsregulatoren und Verfahren dazu |
US8321138B2 (en) * | 2005-07-29 | 2012-11-27 | Agilent Technologies, Inc. | Method of characterizing quality of hybridized CGH arrays |
US20070031883A1 (en) * | 2004-03-04 | 2007-02-08 | Kincaid Robert H | Analyzing CGH data to identify aberrations |
WO2005088306A2 (en) * | 2004-03-04 | 2005-09-22 | Whitehead Institute For Biomedical Research | Biologically-active dna-binding sites and related methods |
US20050282193A1 (en) * | 2004-04-23 | 2005-12-22 | Bulyk Martha L | Space efficient polymer sets |
WO2006028565A2 (en) * | 2004-06-30 | 2006-03-16 | Whitehead Institute For Biomedical Research | Novel methods for high-throughput genome-wide location analysis |
JP2006078313A (ja) * | 2004-09-09 | 2006-03-23 | Hitachi Software Eng Co Ltd | タンパク質の結合位置同定方法 |
US20070099227A1 (en) * | 2004-10-12 | 2007-05-03 | Curry Bo U | Significance analysis using data smoothing with shaped response functions |
JP2009500033A (ja) * | 2005-07-06 | 2009-01-08 | フォルスカルパテント・アイ・ウプサラ・エービー | 核酸付随分子及び修飾の局在化方法 |
WO2007030678A2 (en) * | 2005-09-07 | 2007-03-15 | Whitehead Institute For Biomedical Research | Methods of genome-wide location analysis in stem cells |
US20070190542A1 (en) * | 2005-10-03 | 2007-08-16 | Ling Xinsheng S | Hybridization assisted nanopore sequencing |
US7556921B2 (en) | 2005-12-02 | 2009-07-07 | Whitehead Institute For Biomedical Research | Methods for mapping signal transduction pathways to gene expression programs |
US7297477B2 (en) * | 2006-02-13 | 2007-11-20 | Agilent Technologies, Inc. | Methods and compositions for detecting viral nucleic acid in a cell |
US8071296B2 (en) * | 2006-03-13 | 2011-12-06 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
US8058055B2 (en) * | 2006-04-07 | 2011-11-15 | Agilent Technologies, Inc. | High resolution chromosomal mapping |
US20070238104A1 (en) * | 2006-04-07 | 2007-10-11 | Agilent Technologies, Inc. | Competitive oligonucleotides |
US20080124707A1 (en) * | 2006-06-09 | 2008-05-29 | Agency For Science, Technology And Research | Nucleic acid concatenation |
US7437249B2 (en) | 2006-06-30 | 2008-10-14 | Agilent Technologies, Inc. | Methods and systems for detrending signal intensity data from chemical arrays |
US7881876B2 (en) * | 2006-10-12 | 2011-02-01 | Agilent Technologies, Inc. | Methods and systems for removing offset bias in chemical array data |
US8077951B2 (en) | 2006-10-12 | 2011-12-13 | Agilent Technologies, Inc. | Method and system for dynamic, automated detection of outlying feature and feature background regions during processing of data scanned from a chemical array |
US20080090236A1 (en) * | 2006-10-13 | 2008-04-17 | Yakhini Zohar H | Methods and systems for identifying tumor progression in comparative genomic hybridization data |
US20080102453A1 (en) * | 2006-10-31 | 2008-05-01 | Jayati Ghosh | Methods and systems and analysis of CGH data |
US20090215029A1 (en) * | 2007-01-16 | 2009-08-27 | Cytocure, Inc. | Methods of isolating and purifying nucleic acid-binding biomolecules and compositions including same |
WO2009046094A1 (en) | 2007-10-01 | 2009-04-09 | Nabsys, Inc. | Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment |
US8263367B2 (en) * | 2008-01-25 | 2012-09-11 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
EP2342362B1 (de) * | 2008-09-03 | 2017-03-01 | Nabsys 2.0 LLC | Verwendung von längseits versetzten nanogrossen elektroden zur spannungsmessung von biomolekülen und anderen analyten in fluidischen kanälen |
US9650668B2 (en) | 2008-09-03 | 2017-05-16 | Nabsys 2.0 Llc | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
US8262879B2 (en) | 2008-09-03 | 2012-09-11 | Nabsys, Inc. | Devices and methods for determining the length of biopolymers and distances between probes bound thereto |
EP3216874A1 (de) | 2008-09-05 | 2017-09-13 | TOMA Biosciences, Inc. | Verfahren zum stratifizieren und annotieren der behandlungsoptionen eines krebsmedikaments |
EP3572528A1 (de) | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer |
US8715933B2 (en) | 2010-09-27 | 2014-05-06 | Nabsys, Inc. | Assay methods using nicking endonucleases |
US20120115132A1 (en) | 2010-11-05 | 2012-05-10 | Chromatin, Inc. | Identification of centromere sequences using centromere associated proteins and uses thereof |
US8859201B2 (en) | 2010-11-16 | 2014-10-14 | Nabsys, Inc. | Methods for sequencing a biomolecule by detecting relative positions of hybridized probes |
WO2012109574A2 (en) | 2011-02-11 | 2012-08-16 | Nabsys, Inc. | Assay methods using dna binding proteins |
CA2876304C (en) * | 2012-06-14 | 2021-07-20 | Whitehead Institute For Biomedical Research | Genome-wide method of assessing interactions between chemical entities and their target molecules |
JP2015534063A (ja) | 2012-09-26 | 2015-11-26 | ナブシス, インコーポレイテッド | Dnaおよびrna上のタンパク質およびその他修飾の解析のための方法およびシステム |
US9914966B1 (en) | 2012-12-20 | 2018-03-13 | Nabsys 2.0 Llc | Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation |
WO2014113557A1 (en) | 2013-01-18 | 2014-07-24 | Nabsys, Inc. | Enhanced probe binding |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4882269A (en) * | 1985-12-13 | 1989-11-21 | Princeton University | Amplified hybridization assay |
US6046165A (en) * | 1997-06-23 | 2000-04-04 | Ophidian Pharmaceuticals, Inc. | Compositions and methods for identifying and testing TGF-β pathway agonists and antagonists |
US6066452A (en) * | 1997-08-06 | 2000-05-23 | Yale University | Multiplex selection technique for identifying protein-binding sites and DNA-binding proteins |
US6109776A (en) * | 1998-04-21 | 2000-08-29 | Gene Logic, Inc. | Method and system for computationally identifying clusters within a set of sequences |
-
2000
- 2000-09-01 DE DE60045796T patent/DE60045796D1/de not_active Expired - Lifetime
- 2000-09-01 JP JP2001520923A patent/JP2003508066A/ja active Pending
- 2000-09-01 EP EP00959909A patent/EP1220949B1/de not_active Expired - Lifetime
- 2000-09-01 WO PCT/US2000/024358 patent/WO2001016378A2/en active Application Filing
- 2000-09-01 CA CA002383928A patent/CA2383928A1/en not_active Abandoned
- 2000-09-01 DE DE2000959909 patent/DE00959909T1/de active Pending
- 2000-09-01 AT AT00959909T patent/ATE503843T1/de not_active IP Right Cessation
- 2000-09-01 US US09/654,409 patent/US6410243B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2003508066A (ja) | 2003-03-04 |
CA2383928A1 (en) | 2001-03-08 |
WO2001016378A9 (en) | 2002-11-28 |
EP1220949B1 (de) | 2011-03-30 |
WO2001016378A3 (en) | 2002-05-02 |
WO2001016378A2 (en) | 2001-03-08 |
DE00959909T1 (de) | 2005-11-10 |
DE60045796D1 (de) | 2011-05-12 |
US6410243B1 (en) | 2002-06-25 |
EP1220949A2 (de) | 2002-07-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |