DE60045796D1 - Gesamt-chromosom analyse von protein-dns wechselwirkungen - Google Patents
Gesamt-chromosom analyse von protein-dns wechselwirkungenInfo
- Publication number
- DE60045796D1 DE60045796D1 DE60045796T DE60045796T DE60045796D1 DE 60045796 D1 DE60045796 D1 DE 60045796D1 DE 60045796 T DE60045796 T DE 60045796T DE 60045796 T DE60045796 T DE 60045796T DE 60045796 D1 DE60045796 D1 DE 60045796D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- cell
- genomic dna
- dns
- interactions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15197299P | 1999-09-01 | 1999-09-01 | |
PCT/US2000/024358 WO2001016378A2 (en) | 1999-09-01 | 2000-09-01 | Chromosome-wide analysis of protein-dna interactions |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60045796D1 true DE60045796D1 (de) | 2011-05-12 |
Family
ID=22541045
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60045796T Expired - Lifetime DE60045796D1 (de) | 1999-09-01 | 2000-09-01 | Gesamt-chromosom analyse von protein-dns wechselwirkungen |
DE2000959909 Pending DE00959909T1 (de) | 1999-09-01 | 2000-09-01 | Gesamt-chromosom analyse von protein-dns wechselwirkungen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2000959909 Pending DE00959909T1 (de) | 1999-09-01 | 2000-09-01 | Gesamt-chromosom analyse von protein-dns wechselwirkungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US6410243B1 (de) |
EP (1) | EP1220949B1 (de) |
JP (1) | JP2003508066A (de) |
AT (1) | ATE503843T1 (de) |
CA (1) | CA2383928A1 (de) |
DE (2) | DE60045796D1 (de) |
WO (1) | WO2001016378A2 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7470507B2 (en) * | 1999-09-01 | 2008-12-30 | Whitehead Institute For Biomedical Research | Genome-wide location and function of DNA binding proteins |
US20030087231A1 (en) * | 2000-05-19 | 2003-05-08 | Albertson Donna G. | Methods and compositions for preparation of a polynucleotide array |
WO2002022884A2 (en) * | 2000-09-12 | 2002-03-21 | Transgenetics Incorporated | Microarrayed organization of transcription factor target genes |
DE10056899A1 (de) | 2000-11-16 | 2002-05-29 | Aventis Pharma Gmbh | Promotor zur funktionellen Charakterisierung von G-Protein gekoppelten Rezeptoren in der Hefe Saccharomyces cerevisiae |
CA2432346A1 (en) * | 2000-12-21 | 2002-08-01 | Whitehead Institute For Biomedical Research | Genome-wide location and function of dna binding proteins |
US20040058356A1 (en) * | 2001-03-01 | 2004-03-25 | Warren Mary E. | Methods for global profiling gene regulatory element activity |
WO2004024084A2 (en) * | 2002-09-12 | 2004-03-25 | Massachusetts Institute Of Technology | Rb pahtway and chromatin remodeling genes that antagonize let-60 ras signaling |
US20060099713A1 (en) * | 2002-10-01 | 2006-05-11 | Buck Institute | Targeted-assisted iterative screening (tais):a novel screening format for large molecular repertoires |
US20040161779A1 (en) * | 2002-11-12 | 2004-08-19 | Affymetrix, Inc. | Methods, compositions and computer software products for interrogating sequence variations in functional genomic regions |
US20040115794A1 (en) * | 2002-12-12 | 2004-06-17 | Affymetrix, Inc. | Methods for detecting transcriptional factor binding sites |
US7750908B2 (en) * | 2003-04-04 | 2010-07-06 | Agilent Technologies, Inc. | Focus plus context viewing and manipulation of large collections of graphs |
NZ545000A (en) | 2003-07-03 | 2008-08-29 | Univ California | Genome mapping of functional DNA elements and cellular proteins |
US8222005B2 (en) * | 2003-09-17 | 2012-07-17 | Agency For Science, Technology And Research | Method for gene identification signature (GIS) analysis |
US20050239106A1 (en) * | 2003-11-26 | 2005-10-27 | Whitehead Institute For Biomedical Research | Transcriptional regulators and methods thereof |
US20070031883A1 (en) * | 2004-03-04 | 2007-02-08 | Kincaid Robert H | Analyzing CGH data to identify aberrations |
US8321138B2 (en) * | 2005-07-29 | 2012-11-27 | Agilent Technologies, Inc. | Method of characterizing quality of hybridized CGH arrays |
US7611838B2 (en) * | 2004-03-04 | 2009-11-03 | Whitehead Institute For Biomedical Research | Biologically-active DNA-binding sites and related methods |
US20050282193A1 (en) * | 2004-04-23 | 2005-12-22 | Bulyk Martha L | Space efficient polymer sets |
WO2006028565A2 (en) * | 2004-06-30 | 2006-03-16 | Whitehead Institute For Biomedical Research | Novel methods for high-throughput genome-wide location analysis |
JP2006078313A (ja) * | 2004-09-09 | 2006-03-23 | Hitachi Software Eng Co Ltd | タンパク質の結合位置同定方法 |
US20070099227A1 (en) * | 2004-10-12 | 2007-05-03 | Curry Bo U | Significance analysis using data smoothing with shaped response functions |
US20090011955A1 (en) * | 2005-07-06 | 2009-01-08 | Forskarpatent L Uppsala Ab | Method for Localization of Nucleic Acid Associated Molecules and Modifications |
US20090221428A1 (en) * | 2005-09-07 | 2009-09-03 | Young Richard A | Methods of Genome-Wide Location Analysis in Stem Cells |
WO2007041621A2 (en) * | 2005-10-03 | 2007-04-12 | Xingsheng Sean Ling | Hybridization assisted nanopore sequencing |
WO2007064898A2 (en) * | 2005-12-02 | 2007-06-07 | Whitehead Institute For Biomedical Research | Methods for mapping signal transduction pathways to gene expression programs |
US7297477B2 (en) * | 2006-02-13 | 2007-11-20 | Agilent Technologies, Inc. | Methods and compositions for detecting viral nucleic acid in a cell |
US8071296B2 (en) * | 2006-03-13 | 2011-12-06 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
US8058055B2 (en) * | 2006-04-07 | 2011-11-15 | Agilent Technologies, Inc. | High resolution chromosomal mapping |
US20070238104A1 (en) * | 2006-04-07 | 2007-10-11 | Agilent Technologies, Inc. | Competitive oligonucleotides |
US20080124707A1 (en) * | 2006-06-09 | 2008-05-29 | Agency For Science, Technology And Research | Nucleic acid concatenation |
US7437249B2 (en) | 2006-06-30 | 2008-10-14 | Agilent Technologies, Inc. | Methods and systems for detrending signal intensity data from chemical arrays |
US8077951B2 (en) | 2006-10-12 | 2011-12-13 | Agilent Technologies, Inc. | Method and system for dynamic, automated detection of outlying feature and feature background regions during processing of data scanned from a chemical array |
US7881876B2 (en) * | 2006-10-12 | 2011-02-01 | Agilent Technologies, Inc. | Methods and systems for removing offset bias in chemical array data |
US20080090236A1 (en) * | 2006-10-13 | 2008-04-17 | Yakhini Zohar H | Methods and systems for identifying tumor progression in comparative genomic hybridization data |
US20080102453A1 (en) * | 2006-10-31 | 2008-05-01 | Jayati Ghosh | Methods and systems and analysis of CGH data |
EP2126075A2 (de) * | 2007-01-16 | 2009-12-02 | Cytocure, Inc. | Verfahren zur isolierung und reinigung nukleinsäurebindender biomoleküle und zusammensetzungen damit |
US8278047B2 (en) | 2007-10-01 | 2012-10-02 | Nabsys, Inc. | Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment |
US8263367B2 (en) * | 2008-01-25 | 2012-09-11 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
US9650668B2 (en) | 2008-09-03 | 2017-05-16 | Nabsys 2.0 Llc | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
US8262879B2 (en) | 2008-09-03 | 2012-09-11 | Nabsys, Inc. | Devices and methods for determining the length of biopolymers and distances between probes bound thereto |
US8882980B2 (en) * | 2008-09-03 | 2014-11-11 | Nabsys, Inc. | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
US8583380B2 (en) | 2008-09-05 | 2013-11-12 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
EP2619329B1 (de) | 2010-09-24 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer |
US8715933B2 (en) | 2010-09-27 | 2014-05-06 | Nabsys, Inc. | Assay methods using nicking endonucleases |
US20120115132A1 (en) | 2010-11-05 | 2012-05-10 | Chromatin, Inc. | Identification of centromere sequences using centromere associated proteins and uses thereof |
US8859201B2 (en) | 2010-11-16 | 2014-10-14 | Nabsys, Inc. | Methods for sequencing a biomolecule by detecting relative positions of hybridized probes |
US11274341B2 (en) | 2011-02-11 | 2022-03-15 | NABsys, 2.0 LLC | Assay methods using DNA binding proteins |
WO2013188789A2 (en) * | 2012-06-14 | 2013-12-19 | Whitehead Institute For Biomedical Research | Genome-wide method of assessing interactions between chemical entities and their target molecules |
EP2912461A2 (de) | 2012-09-26 | 2015-09-02 | Nabsys, Inc. | Verfahren und system zur analyse von proteinen und anderen veränderungen bei dna und rna |
US9914966B1 (en) | 2012-12-20 | 2018-03-13 | Nabsys 2.0 Llc | Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation |
US10294516B2 (en) | 2013-01-18 | 2019-05-21 | Nabsys 2.0 Llc | Enhanced probe binding |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4882269A (en) * | 1985-12-13 | 1989-11-21 | Princeton University | Amplified hybridization assay |
US6046165A (en) * | 1997-06-23 | 2000-04-04 | Ophidian Pharmaceuticals, Inc. | Compositions and methods for identifying and testing TGF-β pathway agonists and antagonists |
US6066452A (en) * | 1997-08-06 | 2000-05-23 | Yale University | Multiplex selection technique for identifying protein-binding sites and DNA-binding proteins |
US6109776A (en) * | 1998-04-21 | 2000-08-29 | Gene Logic, Inc. | Method and system for computationally identifying clusters within a set of sequences |
-
2000
- 2000-09-01 JP JP2001520923A patent/JP2003508066A/ja active Pending
- 2000-09-01 CA CA002383928A patent/CA2383928A1/en not_active Abandoned
- 2000-09-01 DE DE60045796T patent/DE60045796D1/de not_active Expired - Lifetime
- 2000-09-01 US US09/654,409 patent/US6410243B1/en not_active Expired - Lifetime
- 2000-09-01 EP EP00959909A patent/EP1220949B1/de not_active Expired - Lifetime
- 2000-09-01 DE DE2000959909 patent/DE00959909T1/de active Pending
- 2000-09-01 WO PCT/US2000/024358 patent/WO2001016378A2/en active Application Filing
- 2000-09-01 AT AT00959909T patent/ATE503843T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1220949A2 (de) | 2002-07-10 |
WO2001016378A3 (en) | 2002-05-02 |
WO2001016378A9 (en) | 2002-11-28 |
WO2001016378A2 (en) | 2001-03-08 |
US6410243B1 (en) | 2002-06-25 |
JP2003508066A (ja) | 2003-03-04 |
ATE503843T1 (de) | 2011-04-15 |
DE00959909T1 (de) | 2005-11-10 |
CA2383928A1 (en) | 2001-03-08 |
EP1220949B1 (de) | 2011-03-30 |
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