DE69610104T2 - Kondensierte thiazol-derivate, mit 5-ht-rezeptor affinität - Google Patents

Kondensierte thiazol-derivate, mit 5-ht-rezeptor affinität

Info

Publication number
DE69610104T2
DE69610104T2 DE69610104T DE69610104T DE69610104T2 DE 69610104 T2 DE69610104 T2 DE 69610104T2 DE 69610104 T DE69610104 T DE 69610104T DE 69610104 T DE69610104 T DE 69610104T DE 69610104 T2 DE69610104 T2 DE 69610104T2
Authority
DE
Germany
Prior art keywords
receptor affinity
thiazole derivatives
condensed thiazole
condensed
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69610104T
Other languages
English (en)
Other versions
DE69610104D1 (de
Inventor
Frank Kerrigan
Crawford Cheetham
Roy Victor Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of DE69610104D1 publication Critical patent/DE69610104D1/de
Publication of DE69610104T2 publication Critical patent/DE69610104T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE69610104T 1995-07-01 1996-06-20 Kondensierte thiazol-derivate, mit 5-ht-rezeptor affinität Expired - Fee Related DE69610104T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9513467.2A GB9513467D0 (en) 1995-07-01 1995-07-01 Therapeutic agents
PCT/EP1996/002676 WO1997002269A1 (en) 1995-07-01 1996-06-20 Condensed thiazole derivatives, having 5-ht receptor affinity

Publications (2)

Publication Number Publication Date
DE69610104D1 DE69610104D1 (de) 2000-10-05
DE69610104T2 true DE69610104T2 (de) 2001-01-18

Family

ID=10777016

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69610104T Expired - Fee Related DE69610104T2 (de) 1995-07-01 1996-06-20 Kondensierte thiazol-derivate, mit 5-ht-rezeptor affinität

Country Status (30)

Country Link
US (1) US5869492A (de)
EP (1) EP0836606B1 (de)
JP (1) JPH11508568A (de)
KR (1) KR19990028619A (de)
CN (1) CN1064966C (de)
AR (1) AR003963A1 (de)
AT (1) ATE195942T1 (de)
AU (1) AU708789B2 (de)
BG (1) BG63206B1 (de)
BR (1) BR9609525A (de)
CA (1) CA2222725A1 (de)
CO (1) CO4700463A1 (de)
CZ (1) CZ376297A3 (de)
DE (1) DE69610104T2 (de)
DK (1) DK0836606T3 (de)
ES (1) ES2151175T3 (de)
GB (1) GB9513467D0 (de)
GR (1) GR3034397T3 (de)
HR (1) HRP960306B1 (de)
HU (1) HUP9901258A3 (de)
IL (1) IL122158A (de)
NO (1) NO310660B1 (de)
NZ (1) NZ312130A (de)
PL (1) PL324337A1 (de)
PT (1) PT836606E (de)
SK (1) SK179297A3 (de)
TR (1) TR199701756T1 (de)
TW (1) TW474939B (de)
WO (1) WO1997002269A1 (de)
ZA (1) ZA965494B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9705428D0 (en) 1997-03-15 1997-04-30 Knoll Ag Therapeutic agents
WO1999050260A1 (fr) 1998-03-31 1999-10-07 Shionogi & Co., Ltd. PROCEDE DE PRODUCTION DE DERIVES D'ACIDE 5-HYDROXYBENZO[b]THIOPHENE-3-CARBOXYLIQUE
DE19908536A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische Thiazol-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB9911881D0 (en) * 1999-05-21 1999-07-21 Knoll Ag Therapeutic agents
GB9911863D0 (en) * 1999-05-21 1999-07-21 Knoll Ag Therapeutic agents
GB0005789D0 (en) * 2000-03-11 2000-05-03 Knoll Ag Therapeutic agents
GB0023610D0 (en) * 2000-09-27 2000-11-08 Knoll Ag Therapeutic agents
DE10112197A1 (de) * 2001-03-14 2002-09-19 Gruenenthal Gmbh Substituierte Pyrazolo- und Thiazolopyrimidine
US8106074B2 (en) 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002400A1 (de) * 1977-11-24 1979-06-13 Synthelabo Thiazolderivate, ihre Herstellung, Zwischenprodukte und ihre Verwendung in der Therapie
JPH07508741A (ja) * 1992-07-13 1995-09-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 新規４−（３−ベンゾフラニル）ピペリジニル及び４−（３−ベンゾチエニル）ピペリジニル誘導体，ならびにそれらを含む製薬学的組成物

Also Published As

Publication number Publication date
HUP9901258A2 (hu) 1999-08-30
AU6358996A (en) 1997-02-05
CO4700463A1 (es) 1998-12-29
BG102084A (en) 1998-08-31
ATE195942T1 (de) 2000-09-15
IL122158A0 (en) 1998-04-05
TW474939B (en) 2002-02-01
HRP960306B1 (en) 2001-08-31
CN1064966C (zh) 2001-04-25
NO310660B1 (no) 2001-08-06
CN1189834A (zh) 1998-08-05
IL122158A (en) 2000-01-31
AU708789B2 (en) 1999-08-12
DK0836606T3 (da) 2000-11-20
KR19990028619A (ko) 1999-04-15
ES2151175T3 (es) 2000-12-16
JPH11508568A (ja) 1999-07-27
CZ376297A3 (cs) 1998-06-17
SK179297A3 (en) 1998-07-08
EP0836606B1 (de) 2000-08-30
GB9513467D0 (en) 1995-09-06
NO976157L (no) 1997-12-30
NO976157D0 (no) 1997-12-30
EP0836606A1 (de) 1998-04-22
AR003963A1 (es) 1998-09-30
HUP9901258A3 (en) 2000-08-28
BG63206B1 (bg) 2001-06-29
DE69610104D1 (de) 2000-10-05
BR9609525A (pt) 1999-02-23
NZ312130A (en) 1999-08-30
CA2222725A1 (en) 1997-01-23
ZA965494B (en) 1997-12-29
TR199701756T1 (xx) 1998-04-21
HRP960306A2 (en) 1998-04-30
US5869492A (en) 1999-02-09
PL324337A1 (en) 1998-05-25
MX9709509A (es) 1998-03-29
PT836606E (pt) 2001-02-28
WO1997002269A1 (en) 1997-01-23
GR3034397T3 (en) 2000-12-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee