DE69535570D1 - In der keratinschicht speicherbares fungizides mittel zur äusserlichen anwendung - Google Patents
In der keratinschicht speicherbares fungizides mittel zur äusserlichen anwendungInfo
- Publication number
- DE69535570D1 DE69535570D1 DE69535570T DE69535570T DE69535570D1 DE 69535570 D1 DE69535570 D1 DE 69535570D1 DE 69535570 T DE69535570 T DE 69535570T DE 69535570 T DE69535570 T DE 69535570T DE 69535570 D1 DE69535570 D1 DE 69535570D1
- Authority
- DE
- Germany
- Prior art keywords
- storable
- external use
- fungicidal agent
- keratin layer
- antifungal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000011782 Keratins Human genes 0.000 title abstract 2
- 108010076876 Keratins Proteins 0.000 title abstract 2
- 239000000417 fungicide Substances 0.000 title 1
- LVYLCBNXHHHPSB-UHFFFAOYSA-N 2-hydroxyethyl salicylate Chemical compound OCCOC(=O)C1=CC=CC=C1O LVYLCBNXHHHPSB-UHFFFAOYSA-N 0.000 abstract 2
- 230000000843 anti-fungal effect Effects 0.000 abstract 2
- 229940121375 antifungal agent Drugs 0.000 abstract 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 abstract 2
- 235000014435 Mentha Nutrition 0.000 abstract 1
- 241001072983 Mentha Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012871 anti-fungal composition Substances 0.000 abstract 1
- DNTGGZPQPQTDQF-XBXARRHUSA-N crotamiton Chemical compound C/C=C/C(=O)N(CC)C1=CC=CC=C1C DNTGGZPQPQTDQF-XBXARRHUSA-N 0.000 abstract 1
- 229960003338 crotamiton Drugs 0.000 abstract 1
- 229960002389 glycol salicylate Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229960001047 methyl salicylate Drugs 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9424394 | 1994-05-06 | ||
JP9424394 | 1994-05-06 | ||
JP06307521A JP3081766B2 (ja) | 1994-05-06 | 1994-12-12 | 角質貯留型抗真菌外用組成物 |
JP30752194 | 1994-12-12 | ||
PCT/JP1995/000773 WO1995030440A1 (fr) | 1994-05-06 | 1995-04-19 | Composition antifongique stockable dans la keratine pour usage externe |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69535570D1 true DE69535570D1 (de) | 2007-10-04 |
DE69535570T2 DE69535570T2 (de) | 2008-01-03 |
Family
ID=26435510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69535570T Expired - Lifetime DE69535570T2 (de) | 1994-05-06 | 1995-04-19 | Antimykotische Zusammensetzung zur äusserlichen Anwendung, die im Stratum Corneum retentiv ist |
Country Status (10)
Country | Link |
---|---|
US (1) | US6017920A (de) |
EP (1) | EP0715856B1 (de) |
JP (1) | JP3081766B2 (de) |
AT (1) | ATE370747T1 (de) |
CA (1) | CA2166388C (de) |
DE (1) | DE69535570T2 (de) |
DK (1) | DK0715856T3 (de) |
ES (1) | ES2293640T3 (de) |
PT (1) | PT715856E (de) |
WO (1) | WO1995030440A1 (de) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4814414B2 (ja) * | 2000-05-26 | 2011-11-16 | 大正製薬株式会社 | 抗真菌液剤組成物 |
US7244703B2 (en) * | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
GB0118300D0 (en) * | 2001-07-26 | 2001-09-19 | Cortendo Ab | Formulations |
JP4963776B2 (ja) * | 2002-03-08 | 2012-06-27 | 第一三共ヘルスケア株式会社 | 抗真菌活性増強型組成物及び抗真菌活性増強方法 |
DE60221903T2 (de) * | 2002-03-25 | 2008-05-08 | Council Of Scientific And Industrial Research | Verwendung synergistischer formulierungen von antifungusmitteln für die behandlung von pilzinfektionen |
DE10224087A1 (de) * | 2002-05-31 | 2003-12-11 | Symrise Gmbh & Co Kg | Kompaktiertes Menthol |
JP4081312B2 (ja) * | 2002-06-28 | 2008-04-23 | 佐藤製薬株式会社 | 外用抗真菌剤 |
AU2003262769A1 (en) * | 2002-08-20 | 2004-03-11 | Pinnell, Doren M | Methods for treating fungal infections |
JP2004083439A (ja) * | 2002-08-23 | 2004-03-18 | Ss Pharmaceut Co Ltd | 爪用抗真菌外用剤 |
US20070099932A1 (en) | 2003-06-25 | 2007-05-03 | Toshihiro Shirouzu | External preparation for athlete's foot treatment |
CN100393314C (zh) * | 2003-09-22 | 2008-06-11 | 北京德众万全药物技术开发有限公司 | 一种利拉萘酯凝胶组合物及其制备方法 |
US7112561B2 (en) | 2003-12-08 | 2006-09-26 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for insulin treatment |
JP4731472B2 (ja) * | 2004-02-27 | 2011-07-27 | 久光製薬株式会社 | 徐放性クリーム剤 |
JP4559753B2 (ja) * | 2004-02-27 | 2010-10-13 | 久光製薬株式会社 | 皮膚外用クリーム剤 |
US20060078580A1 (en) * | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US7740875B2 (en) * | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
EP1708049B1 (de) | 2005-03-31 | 2019-05-08 | Richemont International S.A. | Mondphasenanzeigemechanismus |
JP2007084496A (ja) * | 2005-09-22 | 2007-04-05 | Nippon Nohyaku Co Ltd | 抗真菌剤組成物 |
WO2007102243A1 (ja) * | 2006-03-08 | 2007-09-13 | Nihon Nohyaku Co., Ltd. | 外用の医薬組成物 |
AU2006339842B2 (en) | 2006-03-08 | 2012-06-07 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for external use |
AU2006339841B2 (en) | 2006-03-08 | 2012-08-30 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for external use |
JP5061518B2 (ja) * | 2006-07-12 | 2012-10-31 | 大正製薬株式会社 | アモロルフィン含有o/wエマルション組成物 |
US20080146672A1 (en) * | 2006-12-08 | 2008-06-19 | Denton Marcia Marye | Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue |
US20080153122A1 (en) * | 2006-12-21 | 2008-06-26 | Susan Beth Cantor | Method and system for enhancing self-treatment of onychomycosis |
EP2191827B1 (de) | 2007-09-05 | 2013-10-30 | Pola Pharma Inc. | Antimykotische zusammensetzung |
WO2009031644A1 (ja) | 2007-09-05 | 2009-03-12 | Pola Pharma Inc. | 抗真菌医薬組成物 |
JP5529539B2 (ja) | 2007-09-05 | 2014-06-25 | 株式会社ポーラファルマ | 医薬組成物 |
JP5319950B2 (ja) * | 2008-04-08 | 2013-10-16 | 帝國製薬株式会社 | 塩酸ブテナフィン含有水性貼付剤 |
CN102186341B (zh) | 2008-10-20 | 2013-12-25 | 荷兰联合利华有限公司 | 抗菌组合物 |
EP2745692A1 (de) * | 2009-02-13 | 2014-06-25 | Topica Pharmaceuticals, Inc | Luliconazole-enthaltende antimykotische Formulierung |
US9050271B2 (en) | 2009-04-09 | 2015-06-09 | Pola Pharma Inc. | Antimycotic pharmaceutical composition |
WO2010117089A2 (en) * | 2009-04-09 | 2010-10-14 | Pola Pharma Inc. | Antimycotic pharmaceutical composition |
EP2470178B1 (de) | 2009-08-25 | 2018-10-17 | Pola Pharma Inc. | Antimykotische pharmazeutische zusammensetzung |
EA019746B1 (ru) | 2009-09-24 | 2014-05-30 | Юнилевер Нв | Противомикробная композиция, содержащая эвгенол, терпинеол и тимол, и способ дезинфицирования поверхности |
JP2011173823A (ja) * | 2010-02-24 | 2011-09-08 | Hisamitsu Pharmaceut Co Inc | ゲル製剤 |
EP2579847A1 (de) | 2010-06-11 | 2013-04-17 | Pola Pharma Inc. | Antimykotische pharmazeutische zusammensetzung |
EA022986B1 (ru) | 2010-12-07 | 2016-04-29 | Юнилевер Нв | Композиция для ухода за полостью рта |
JP2012144449A (ja) * | 2011-01-07 | 2012-08-02 | Nippon Nohyaku Co Ltd | ルリコナゾールの皮膚浸透性を向上させる配合処方 |
CN103998011B (zh) | 2011-11-03 | 2016-11-23 | 荷兰联合利华有限公司 | 个人清洁组合物 |
JP6016085B2 (ja) * | 2012-07-13 | 2016-10-26 | ダイヤ製薬株式会社 | 抗真菌外用組成物及び抗真菌外用組成物の適用方法 |
EP2895479A1 (de) | 2012-09-14 | 2015-07-22 | Pola Pharma Inc. | Kristall mit kristallverhalten und durch die verarbeitung des kristalls gewonnene pharmazeutische zusammensetzung |
JP5460797B1 (ja) | 2012-09-14 | 2014-04-02 | 株式会社ポーラファルマ | アミド誘導体及び安定性指標としてのその使用 |
US9068958B1 (en) | 2012-09-14 | 2015-06-30 | Pola Pharma Inc. | Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and pharmaceutical composition prepared by containing the crystal |
RU2622644C2 (ru) | 2012-09-14 | 2017-06-19 | Пола Фарма Инк. | Кристаллическое вещество и содержащий его фармацевтический препарат |
JP5662495B2 (ja) * | 2013-02-08 | 2015-01-28 | 株式会社ポーラファルマ | 可溶化剤形の医薬組成物 |
JP6067399B2 (ja) * | 2013-02-08 | 2017-01-25 | 株式会社ポーラファルマ | 医薬組成物 |
JP5589110B1 (ja) | 2013-03-08 | 2014-09-10 | 株式会社ポーラファルマ | 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物 |
JP5680161B1 (ja) | 2013-09-06 | 2015-03-04 | 株式会社ポーラファルマ | 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物 |
JP5587488B1 (ja) | 2013-12-12 | 2014-09-10 | 株式会社ポーラファルマ | ルリコナゾールを含有する製剤の評価方法及び指標物質 |
JP6634703B2 (ja) * | 2014-06-10 | 2020-01-22 | 大正製薬株式会社 | 外用組成物 |
KR101690765B1 (ko) * | 2015-04-17 | 2016-12-28 | 동아제약 주식회사 | 항진균성 활성물질을 포함하는 경피 제제 |
CN104825388A (zh) * | 2015-04-20 | 2015-08-12 | 陈亚春 | 一种联苯苄唑溶液及其制备方法 |
KR20190067510A (ko) * | 2017-12-07 | 2019-06-17 | 한미약품 주식회사 | 테르비나핀을 포함하는 외용제 조성물 및 그 제조방법 |
CN110063934B (zh) * | 2018-01-22 | 2021-08-06 | 洛阳惠中兽药有限公司 | 一种治疗宠物真菌感染的利拉萘酯外用溶液及其制备方法 |
EP3801455A1 (de) * | 2018-05-30 | 2021-04-14 | Eviderm Institute AB | Milde zusammensetzung zur verwendung in der topischen behandlung von durch einen virus und pilz verursachten haut- und nagelerkrankungen |
JP2022067658A (ja) * | 2020-10-20 | 2022-05-06 | 東光薬品工業株式会社 | 皮膚外用クリーム剤 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5815909A (ja) * | 1981-07-22 | 1983-01-29 | Toko Yakuhin Kogyo Kk | 抗真菌外用剤 |
JPS6061518A (ja) * | 1983-09-14 | 1985-04-09 | Hisamitsu Pharmaceut Co Inc | ゲル状外用組成物 |
US4636520A (en) * | 1984-07-16 | 1987-01-13 | Fujisawa Pharmaceutical Co., Ltd. | Antifungal composition employing pyrrolnitrin in combination with an imidazole compound |
JPH02264723A (ja) * | 1989-04-06 | 1990-10-29 | Taisho Pharmaceut Co Ltd | 抗真菌剤 |
JPH0725675B2 (ja) * | 1989-05-08 | 1995-03-22 | ホーユー株式会社 | 液状真菌症治療剤 |
-
1994
- 1994-12-12 JP JP06307521A patent/JP3081766B2/ja not_active Expired - Lifetime
-
1995
- 1995-04-19 ES ES95916014T patent/ES2293640T3/es not_active Expired - Lifetime
- 1995-04-19 EP EP95916014A patent/EP0715856B1/de not_active Expired - Lifetime
- 1995-04-19 DE DE69535570T patent/DE69535570T2/de not_active Expired - Lifetime
- 1995-04-19 PT PT95916014T patent/PT715856E/pt unknown
- 1995-04-19 AT AT95916014T patent/ATE370747T1/de active
- 1995-04-19 DK DK95916014T patent/DK0715856T3/da active
- 1995-04-19 CA CA002166388A patent/CA2166388C/en not_active Expired - Fee Related
- 1995-04-19 US US08/578,606 patent/US6017920A/en not_active Expired - Lifetime
- 1995-04-19 WO PCT/JP1995/000773 patent/WO1995030440A1/ja active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO1995030440A1 (fr) | 1995-11-16 |
DE69535570T2 (de) | 2008-01-03 |
JPH0820527A (ja) | 1996-01-23 |
DK0715856T3 (da) | 2007-12-10 |
CA2166388C (en) | 2008-06-17 |
ES2293640T3 (es) | 2008-03-16 |
JP3081766B2 (ja) | 2000-08-28 |
PT715856E (pt) | 2007-11-27 |
ATE370747T1 (de) | 2007-09-15 |
US6017920A (en) | 2000-01-25 |
EP0715856A4 (de) | 1997-09-17 |
EP0715856A1 (de) | 1996-06-12 |
CA2166388A1 (en) | 1995-11-16 |
EP0715856B1 (de) | 2007-08-22 |
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