DE69523447T2 - Kristallformen von 1-[5-methansulfonamidoindolyl-2-carbonyl]-4-[3-[1-methylethylamino]-2-pyridinyl] piperazin - Google Patents
Kristallformen von 1-[5-methansulfonamidoindolyl-2-carbonyl]-4-[3-[1-methylethylamino]-2-pyridinyl] piperazinInfo
- Publication number
- DE69523447T2 DE69523447T2 DE69523447T DE69523447T DE69523447T2 DE 69523447 T2 DE69523447 T2 DE 69523447T2 DE 69523447 T DE69523447 T DE 69523447T DE 69523447 T DE69523447 T DE 69523447T DE 69523447 T2 DE69523447 T2 DE 69523447T2
- Authority
- DE
- Germany
- Prior art keywords
- methylethylamino
- pyridinyl
- carbonyl
- piperazine
- crystal forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- ZKJKXGCLZUMGNT-UHFFFAOYSA-N methanesulfonic acid;piperazine Chemical compound CS(O)(=O)=O.C1CNCCN1 ZKJKXGCLZUMGNT-UHFFFAOYSA-N 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22786094A | 1994-04-15 | 1994-04-15 | |
| US31178094A | 1994-09-23 | 1994-09-23 | |
| PCT/US1995/002166 WO1995028398A1 (en) | 1994-04-15 | 1995-03-01 | Novel crystal forms of 1-[5-methanesulfonamidoindolyl-2-carbonyl]-4-[3-(1-methylethylamino)-2-pyridinyl]piperazine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69523447D1 DE69523447D1 (de) | 2001-11-29 |
| DE69523447T2 true DE69523447T2 (de) | 2002-05-16 |
Family
ID=26921831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69523447T Expired - Lifetime DE69523447T2 (de) | 1994-04-15 | 1995-03-01 | Kristallformen von 1-[5-methansulfonamidoindolyl-2-carbonyl]-4-[3-[1-methylethylamino]-2-pyridinyl] piperazin |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6452007B1 (de) |
| EP (1) | EP0755393B1 (de) |
| JP (1) | JP3817261B2 (de) |
| KR (1) | KR100364941B1 (de) |
| CN (1) | CN1147253A (de) |
| AT (1) | ATE207481T1 (de) |
| AU (1) | AU693939B2 (de) |
| CA (1) | CA2184598C (de) |
| CZ (1) | CZ287164B6 (de) |
| DE (1) | DE69523447T2 (de) |
| DK (1) | DK0755393T3 (de) |
| ES (1) | ES2164147T3 (de) |
| FI (1) | FI111364B (de) |
| HU (1) | HU226827B1 (de) |
| IL (1) | IL113162A (de) |
| LV (1) | LV12957B (de) |
| MX (1) | MX9604831A (de) |
| MY (1) | MY116830A (de) |
| NO (1) | NO310024B1 (de) |
| NZ (1) | NZ282211A (de) |
| PL (1) | PL180776B1 (de) |
| PT (1) | PT755393E (de) |
| RU (1) | RU2136677C1 (de) |
| SK (1) | SK282424B6 (de) |
| TW (1) | TW393478B (de) |
| WO (1) | WO1995028398A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6177101B1 (en) | 1998-06-11 | 2001-01-23 | Pharmacia & Upjohn Company | Delavirdine high strength tablet formulation |
| US6872811B1 (en) | 1998-09-30 | 2005-03-29 | Millennium Pharmaceuticals, Inc. | HRPCa9 and HRPCa10 nucleic acids and polypeptides |
| DE102011113749A1 (de) * | 2011-09-14 | 2013-03-14 | Aicuris Gmbh & Co. Kg | Sulfonsäuresalze Heterocyclylamid-substituiertr Imidazole |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3565924A (en) | 1968-07-01 | 1971-02-23 | Wisconsin Alumni Res Found | 25-hydroxycholfcalciferol |
| US3833622A (en) | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
| GB1532682A (en) | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
| IL63968A (en) | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
| US5563142A (en) * | 1989-12-28 | 1996-10-08 | The Upjohn Company | Diaromatic substituted compounds as anti-HIV-1 agents |
| MX9203454A (es) * | 1989-12-28 | 1992-08-01 | Upjohn Co | Compuestos anti sida diaromaticos substituidos. |
| US5599930A (en) * | 1991-07-03 | 1997-02-04 | The Upjohn Company | Substituted indoles as anti-AIDS pharmaceuticals |
-
1995
- 1995-03-01 PT PT95911842T patent/PT755393E/pt unknown
- 1995-03-01 HU HU9602857A patent/HU226827B1/hu unknown
- 1995-03-01 ES ES95911842T patent/ES2164147T3/es not_active Expired - Lifetime
- 1995-03-01 EP EP95911842A patent/EP0755393B1/de not_active Expired - Lifetime
- 1995-03-01 SK SK1229-96A patent/SK282424B6/sk unknown
- 1995-03-01 JP JP52695295A patent/JP3817261B2/ja not_active Expired - Lifetime
- 1995-03-01 RU RU96119978A patent/RU2136677C1/ru active
- 1995-03-01 CZ CZ19962942A patent/CZ287164B6/cs not_active IP Right Cessation
- 1995-03-01 DK DK95911842T patent/DK0755393T3/da active
- 1995-03-01 CN CN95192523A patent/CN1147253A/zh active Pending
- 1995-03-01 PL PL95316688A patent/PL180776B1/pl unknown
- 1995-03-01 MX MX9604831A patent/MX9604831A/es unknown
- 1995-03-01 KR KR1019960705760A patent/KR100364941B1/ko not_active IP Right Cessation
- 1995-03-01 DE DE69523447T patent/DE69523447T2/de not_active Expired - Lifetime
- 1995-03-01 NZ NZ282211A patent/NZ282211A/en not_active IP Right Cessation
- 1995-03-01 CA CA002184598A patent/CA2184598C/en not_active Expired - Lifetime
- 1995-03-01 US US08/732,254 patent/US6452007B1/en not_active Expired - Lifetime
- 1995-03-01 AU AU35136/95A patent/AU693939B2/en not_active Expired
- 1995-03-01 AT AT95911842T patent/ATE207481T1/de active
- 1995-03-01 WO PCT/US1995/002166 patent/WO1995028398A1/en active IP Right Grant
- 1995-03-17 TW TW084102592A patent/TW393478B/zh not_active IP Right Cessation
- 1995-03-28 IL IL11316295A patent/IL113162A/xx not_active IP Right Cessation
- 1995-03-28 MY MYPI95000766A patent/MY116830A/en unknown
-
1996
- 1996-10-14 FI FI964114A patent/FI111364B/fi not_active IP Right Cessation
- 1996-10-15 NO NO964386A patent/NO310024B1/no not_active IP Right Cessation
-
2002
- 2002-10-24 LV LVP-02-186A patent/LV12957B/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |