DE69522411T2 - Trennungsmittel für optische Isomere - Google Patents

Trennungsmittel für optische Isomere

Info

Publication number
DE69522411T2
DE69522411T2 DE69522411T DE69522411T DE69522411T2 DE 69522411 T2 DE69522411 T2 DE 69522411T2 DE 69522411 T DE69522411 T DE 69522411T DE 69522411 T DE69522411 T DE 69522411T DE 69522411 T2 DE69522411 T2 DE 69522411T2
Authority
DE
Germany
Prior art keywords
optical isomers
separating agent
separating
agent
isomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69522411T
Other languages
English (en)
Other versions
DE69522411D1 (de
Inventor
Tatsushi Murakami
Nanami Nishida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chemical Industries Ltd filed Critical Daicel Chemical Industries Ltd
Application granted granted Critical
Publication of DE69522411D1 publication Critical patent/DE69522411D1/de
Publication of DE69522411T2 publication Critical patent/DE69522411T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287Non-polar phases; Reversed phases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004Sorbent size or size distribution, e.g. particle size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • B01J20/28085Pore diameter being more than 50 nm, i.e. macropores
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/29Chiral phases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/40Aspects relating to the composition of sorbent or filter aid materials
    • B01J2220/48Sorbents characterised by the starting material used for their preparation
    • B01J2220/4812Sorbents characterised by the starting material used for their preparation the starting material being of organic character
    • B01J2220/4825Polysaccharides or cellulose materials, e.g. starch, chitin, sawdust, wood, straw, cotton
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58Use in a single column

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DE69522411T 1994-05-17 1995-04-27 Trennungsmittel für optische Isomere Expired - Lifetime DE69522411T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10254894A JP3478595B2 (ja) 1994-05-17 1994-05-17 光学異性体用分離剤
PCT/JP1995/000844 WO1995031420A1 (fr) 1994-05-17 1995-04-27 Agent de separation pour isomeres optiques

Publications (2)

Publication Number Publication Date
DE69522411D1 DE69522411D1 (de) 2001-10-04
DE69522411T2 true DE69522411T2 (de) 2001-12-13

Family

ID=14330306

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522411T Expired - Lifetime DE69522411T2 (de) 1994-05-17 1995-04-27 Trennungsmittel für optische Isomere

Country Status (7)

Country Link
US (1) US5734043A (de)
EP (1) EP0711742B1 (de)
JP (1) JP3478595B2 (de)
KR (1) KR0167138B1 (de)
CN (1) CN1049883C (de)
DE (1) DE69522411T2 (de)
WO (1) WO1995031420A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3493201B2 (ja) * 1995-12-21 2004-02-03 ダイセル化学工業株式会社 高速液体クロマトグラフィー用充填剤
JP4320065B2 (ja) * 1997-10-23 2009-08-26 ダイセル化学工業株式会社 光学異性体分離法
JP2001163806A (ja) * 1999-09-29 2001-06-19 Daicel Chem Ind Ltd 光学異性体分離剤
KR100387932B1 (ko) * 2000-11-09 2003-06-18 현명호 키랄 의약품의 광학분할을 위한 lc 용 키랄 크라운 에테르 키랄 고정상 및 이들로 충진된 키랄 칼럼
US20040149660A1 (en) * 2001-06-15 2004-08-05 Natsuki Kasuya Separatory agent for optical isomer
WO2003004149A1 (fr) 2001-07-06 2003-01-16 Daicel Chemical Industries, Ltd. Agent de separation d'isomere optique et procede de preparation de cet agent
US6691880B2 (en) * 2001-07-12 2004-02-17 Konstant Products, Inc. Pick deck
CA2458133C (en) * 2003-02-18 2011-12-20 Daiso Co., Ltd. Packings for liquid chromatography, process for preparing and usage
ATE506118T1 (de) 2003-04-24 2011-05-15 Daicel Chem Trennbares mittel für optischen isomer
JP4871861B2 (ja) * 2005-03-31 2012-02-08 株式会社ダイセル 光学異性体分離剤
US8362237B2 (en) * 2008-01-31 2013-01-29 National University Corporation Okayama University Optical-isomer separating agent for chromatography and process for producing the same
JP6109604B2 (ja) * 2013-03-05 2017-04-05 嶋田 豊司 オクタヒドロビナフチル誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3483311D1 (de) * 1983-12-28 1990-10-31 Daicel Chem Verfahren zur trennung optischer und geometrischer isomere.
JPS60196663A (ja) * 1984-03-19 1985-10-05 Daicel Chem Ind Ltd 分離剤
US4683341A (en) * 1984-12-19 1987-07-28 Daicel Chemical Industries, Ltd. Optical resolution of oxycyclopentenone
US5302633A (en) * 1990-11-29 1994-04-12 Nacalai Tesque, Inc. Optical resolution agent and process for the preparation of the same
JP3258783B2 (ja) * 1992-10-28 2002-02-18 ダイセル化学工業株式会社 新規オリゴ糖誘導体及びその用途
JP3848377B2 (ja) * 1993-05-24 2006-11-22 ダイセル化学工業株式会社 分離剤の製造法
JP3190206B2 (ja) * 1993-06-22 2001-07-23 ダイセル化学工業株式会社 光学異性体用分離剤およびその製造法

Also Published As

Publication number Publication date
EP0711742B1 (de) 2001-08-29
CN1130375A (zh) 1996-09-04
CN1049883C (zh) 2000-03-01
KR960703827A (ko) 1996-08-31
JPH07309784A (ja) 1995-11-28
DE69522411D1 (de) 2001-10-04
US5734043A (en) 1998-03-31
WO1995031420A1 (fr) 1995-11-23
KR0167138B1 (ko) 1999-03-20
EP0711742A1 (de) 1996-05-15
JP3478595B2 (ja) 2003-12-15
EP0711742A4 (de) 1997-01-08

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