DE69522119T2 - Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen - Google Patents

Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Info

Publication number
DE69522119T2
DE69522119T2 DE69522119T DE69522119T DE69522119T2 DE 69522119 T2 DE69522119 T2 DE 69522119T2 DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T2 DE69522119 T2 DE 69522119T2
Authority
DE
Germany
Prior art keywords
inhaler
inhalation
inhalation device
piston
air outlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69522119T
Other languages
German (de)
English (en)
Other versions
DE69522119D1 (de
Inventor
Kjell Wetterlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69522119D1 publication Critical patent/DE69522119D1/de
Publication of DE69522119T2 publication Critical patent/DE69522119T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A61M15/0088—Inhalation chambers with variable volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE69522119T 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen Expired - Lifetime DE69522119T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404439A SE9404439D0 (sv) 1994-12-21 1994-12-21 Inhalation device
PCT/SE1995/001539 WO1996019253A1 (en) 1994-12-21 1995-12-19 An inhalation device, a method of dispersing a pharmaceutically acitve substance and a method of administering a dose of a pharmaceutically active substance

Publications (2)

Publication Number Publication Date
DE69522119D1 DE69522119D1 (de) 2001-09-13
DE69522119T2 true DE69522119T2 (de) 2002-06-06

Family

ID=20396408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522119T Expired - Lifetime DE69522119T2 (de) 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Country Status (25)

Country Link
US (1) US5983893A (enExample)
EP (1) EP0799067B1 (enExample)
JP (1) JP3712415B2 (enExample)
CN (1) CN1171056A (enExample)
AR (1) AR000522A1 (enExample)
AT (1) ATE203919T1 (enExample)
AU (1) AU698815B2 (enExample)
BR (1) BR9510210A (enExample)
CA (1) CA2207436A1 (enExample)
CZ (1) CZ191397A3 (enExample)
DE (1) DE69522119T2 (enExample)
EE (1) EE9700132A (enExample)
FI (1) FI972697A0 (enExample)
HU (1) HUT77661A (enExample)
IL (1) IL116457A0 (enExample)
IS (2) IS4508A (enExample)
NO (1) NO972780D0 (enExample)
NZ (1) NZ298166A (enExample)
PL (1) PL179323B1 (enExample)
SE (1) SE9404439D0 (enExample)
SK (1) SK78297A3 (enExample)
TR (1) TR199501636A1 (enExample)
TW (1) TW286285B (enExample)
WO (1) WO1996019253A1 (enExample)
ZA (1) ZA9510747B (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit

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US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
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PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
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AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
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AU2007210177C1 (en) * 2006-01-31 2012-11-01 Oriel Therapeutics, Inc. Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
WO2008144106A1 (en) * 2007-05-16 2008-11-27 Aradigm Corporation Burst valve for aerosol device
WO2009079078A1 (en) 2007-12-14 2009-06-25 Labogroup S.A.S. Delivering aerosolizable food products
AU2009228074B2 (en) * 2008-03-27 2015-01-22 Mannkind Corporation A dry powder inhalation system
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
US9603907B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Dry powder formulations of dNase I
EP3421042B1 (en) 2012-03-07 2024-04-17 Beyond Air Ltd Inhalation of nitric oxide for treating respiratory diseases
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EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
TWI595902B (zh) 2016-05-10 2017-08-21 明基材料股份有限公司 攜帶型負壓裝置
KR20220002600A (ko) 2019-04-29 2022-01-06 인스메드 인코포레이티드 트레프로스티닐 전구약물의 건조 분말 조성물 및 이의 사용 방법
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
US8807132B2 (en) 2006-02-17 2014-08-19 Sanofi Sa Dispersing unit

Also Published As

Publication number Publication date
NZ298166A (en) 1999-01-28
IL116457A0 (en) 1996-03-31
FI972697A7 (fi) 1997-06-23
BR9510210A (pt) 1997-11-04
TR199501636A1 (tr) 1997-03-21
WO1996019253A1 (en) 1996-06-27
IS4509A (is) 1997-06-18
TW286285B (enExample) 1996-09-21
PL320860A1 (en) 1997-11-10
CZ191397A3 (en) 1997-10-15
ZA9510747B (en) 1996-06-28
AR000522A1 (es) 1997-07-10
MX9704489A (es) 1997-10-31
SK78297A3 (en) 1998-02-04
ATE203919T1 (de) 2001-08-15
EP0799067A1 (en) 1997-10-08
NO972780L (no) 1997-06-16
DE69522119D1 (de) 2001-09-13
US5983893A (en) 1999-11-16
AU4359096A (en) 1996-07-10
IS4508A (is) 1997-06-16
NO972780D0 (no) 1997-06-16
CN1171056A (zh) 1998-01-21
PL179323B1 (pl) 2000-08-31
CA2207436A1 (en) 1996-06-27
AU698815B2 (en) 1998-11-05
JP3712415B2 (ja) 2005-11-02
EP0799067B1 (en) 2001-08-08
EE9700132A (et) 1997-12-15
SE9404439D0 (sv) 1994-12-21
HUT77661A (hu) 1998-07-28
JPH10510742A (ja) 1998-10-20
FI972697A0 (fi) 1997-06-23

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