DE69522119T2 - Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen - Google Patents

Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Info

Publication number
DE69522119T2
DE69522119T2 DE69522119T DE69522119T DE69522119T2 DE 69522119 T2 DE69522119 T2 DE 69522119T2 DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T2 DE69522119 T2 DE 69522119T2
Authority
DE
Germany
Prior art keywords
inhaler
inhalation
inhalation device
piston
air outlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69522119T
Other languages
German (de)
English (en)
Other versions
DE69522119D1 (de
Inventor
Kjell Wetterlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69522119D1 publication Critical patent/DE69522119D1/de
Publication of DE69522119T2 publication Critical patent/DE69522119T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A61M15/0088—Inhalation chambers with variable volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE69522119T 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen Expired - Lifetime DE69522119T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404439A SE9404439D0 (sv) 1994-12-21 1994-12-21 Inhalation device
PCT/SE1995/001539 WO1996019253A1 (en) 1994-12-21 1995-12-19 An inhalation device, a method of dispersing a pharmaceutically acitve substance and a method of administering a dose of a pharmaceutically active substance

Publications (2)

Publication Number Publication Date
DE69522119D1 DE69522119D1 (de) 2001-09-13
DE69522119T2 true DE69522119T2 (de) 2002-06-06

Family

ID=20396408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522119T Expired - Lifetime DE69522119T2 (de) 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Country Status (25)

Country Link
US (1) US5983893A (enExample)
EP (1) EP0799067B1 (enExample)
JP (1) JP3712415B2 (enExample)
CN (1) CN1171056A (enExample)
AR (1) AR000522A1 (enExample)
AT (1) ATE203919T1 (enExample)
AU (1) AU698815B2 (enExample)
BR (1) BR9510210A (enExample)
CA (1) CA2207436A1 (enExample)
CZ (1) CZ191397A3 (enExample)
DE (1) DE69522119T2 (enExample)
EE (1) EE9700132A (enExample)
FI (1) FI972697A7 (enExample)
HU (1) HUT77661A (enExample)
IL (1) IL116457A0 (enExample)
IS (2) IS4508A (enExample)
NO (1) NO972780L (enExample)
NZ (1) NZ298166A (enExample)
PL (1) PL179323B1 (enExample)
SE (1) SE9404439D0 (enExample)
SK (1) SK78297A3 (enExample)
TR (1) TR199501636A1 (enExample)
TW (1) TW286285B (enExample)
WO (1) WO1996019253A1 (enExample)
ZA (1) ZA9510747B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit

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ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
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CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
WO2008144106A1 (en) * 2007-05-16 2008-11-27 Aradigm Corporation Burst valve for aerosol device
EP2534957B1 (en) 2007-12-14 2015-05-27 AeroDesigns, Inc Delivering aerosolizable products
CA2719205C (en) * 2008-03-27 2017-04-25 Mannkind Corporation A dry powder inhalation system
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MY155524A (en) 2008-06-13 2015-10-30 Mannkind Corp A dry powder inhaler and system for drug delivery
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
AU2010259943C1 (en) 2009-06-12 2016-03-03 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
MX353285B (es) 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
WO2013114371A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Dry powder formulations of dnase i
WO2013132497A1 (en) 2012-03-07 2013-09-12 Advanced Inhilation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
TWI595902B (zh) 2016-05-10 2017-08-21 明基材料股份有限公司 攜帶型負壓裝置
CN119632930A (zh) 2019-04-29 2025-03-18 英斯梅德股份有限公司 曲前列素前药的干粉组合物及其使用方法
CN116437906B (zh) 2020-10-28 2026-07-03 英斯梅德股份有限公司 曲前列环素前药的干粉组合物和其使用方法
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
US8807132B2 (en) 2006-02-17 2014-08-19 Sanofi Sa Dispersing unit

Also Published As

Publication number Publication date
CA2207436A1 (en) 1996-06-27
ZA9510747B (en) 1996-06-28
FI972697A0 (fi) 1997-06-23
US5983893A (en) 1999-11-16
TW286285B (enExample) 1996-09-21
NO972780D0 (no) 1997-06-16
EP0799067A1 (en) 1997-10-08
AR000522A1 (es) 1997-07-10
FI972697A7 (fi) 1997-06-23
CZ191397A3 (en) 1997-10-15
EE9700132A (et) 1997-12-15
WO1996019253A1 (en) 1996-06-27
AU4359096A (en) 1996-07-10
SK78297A3 (en) 1998-02-04
NO972780L (no) 1997-06-16
PL179323B1 (pl) 2000-08-31
DE69522119D1 (de) 2001-09-13
MX9704489A (es) 1997-10-31
TR199501636A1 (tr) 1997-03-21
NZ298166A (en) 1999-01-28
JP3712415B2 (ja) 2005-11-02
IS4508A (is) 1997-06-16
PL320860A1 (en) 1997-11-10
IS4509A (is) 1997-06-18
ATE203919T1 (de) 2001-08-15
SE9404439D0 (sv) 1994-12-21
IL116457A0 (en) 1996-03-31
AU698815B2 (en) 1998-11-05
BR9510210A (pt) 1997-11-04
JPH10510742A (ja) 1998-10-20
HUT77661A (hu) 1998-07-28
CN1171056A (zh) 1998-01-21
EP0799067B1 (en) 2001-08-08

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