DE69516524D1 - Therapeutisch verwendbare spiro-azabicyclische verbindungen - Google Patents

Therapeutisch verwendbare spiro-azabicyclische verbindungen

Info

Publication number
DE69516524D1
DE69516524D1 DE69516524T DE69516524T DE69516524D1 DE 69516524 D1 DE69516524 D1 DE 69516524D1 DE 69516524 T DE69516524 T DE 69516524T DE 69516524 T DE69516524 T DE 69516524T DE 69516524 D1 DE69516524 D1 DE 69516524D1
Authority
DE
Germany
Prior art keywords
spiro
azabicyclic compounds
therapeutically applicable
therapeutically
applicable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69516524T
Other languages
English (en)
Other versions
DE69516524T2 (de
Inventor
Michael Balestra
Charles Gordon
Conrad Griffith
John Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9417084A external-priority patent/GB9417084D0/en
Priority claimed from GBGB9504627.2A external-priority patent/GB9504627D0/en
Application filed by Astra AB filed Critical Astra AB
Publication of DE69516524D1 publication Critical patent/DE69516524D1/de
Application granted granted Critical
Publication of DE69516524T2 publication Critical patent/DE69516524T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69516524T 1994-08-24 1995-08-22 Therapeutisch verwendbare spiro-azabicyclische verbindungen Expired - Fee Related DE69516524T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9417084A GB9417084D0 (en) 1994-08-24 1994-08-24 Compounds useful in therapy
GBGB9504627.2A GB9504627D0 (en) 1995-03-08 1995-03-08 Compounds for use in therapy
PCT/SE1995/000937 WO1996006098A1 (en) 1994-08-24 1995-08-22 Spiro-azabicyclic compounds useful in therapy

Publications (2)

Publication Number Publication Date
DE69516524D1 true DE69516524D1 (de) 2000-05-31
DE69516524T2 DE69516524T2 (de) 2001-01-18

Family

ID=26305509

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69516524T Expired - Fee Related DE69516524T2 (de) 1994-08-24 1995-08-22 Therapeutisch verwendbare spiro-azabicyclische verbindungen

Country Status (34)

Country Link
US (2) US5902814A (de)
EP (1) EP0777671B1 (de)
JP (1) JP3708962B2 (de)
KR (1) KR100366331B1 (de)
CN (2) CN1056846C (de)
AR (1) AR031828A2 (de)
AT (1) ATE192157T1 (de)
AU (1) AU690735B2 (de)
BR (1) BR9508751A (de)
CA (1) CA2196995C (de)
CZ (1) CZ289512B6 (de)
DE (1) DE69516524T2 (de)
DK (1) DK0777671T3 (de)
EE (1) EE03399B1 (de)
EG (1) EG24222A (de)
ES (1) ES2145922T3 (de)
FI (1) FI112868B (de)
GR (1) GR3033878T3 (de)
HK (1) HK1010370A1 (de)
HU (1) HUT77352A (de)
IL (1) IL115039A (de)
IS (1) IS1852B (de)
MX (1) MX9701292A (de)
NO (1) NO307707B1 (de)
NZ (1) NZ292289A (de)
PL (1) PL183933B1 (de)
PT (1) PT777671E (de)
RU (1) RU2148058C1 (de)
SA (1) SA95160370B1 (de)
SK (1) SK282366B6 (de)
TR (1) TR199501053A2 (de)
TW (1) TW397837B (de)
UA (1) UA54375C2 (de)
WO (1) WO1996006098A1 (de)

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Also Published As

Publication number Publication date
ES2145922T3 (es) 2000-07-16
AU3401895A (en) 1996-03-14
WO1996006098A1 (en) 1996-02-29
IL115039A0 (en) 1995-12-08
CZ39297A3 (en) 1997-12-17
EE03399B1 (et) 2001-04-16
SK282366B6 (sk) 2002-01-07
PL318760A1 (en) 1997-07-07
UA54375C2 (uk) 2003-03-17
FI970762A0 (fi) 1997-02-24
EG24222A (en) 2008-11-10
IL115039A (en) 2001-08-26
FI112868B (fi) 2004-01-30
MX9701292A (es) 1997-05-31
PL183933B1 (pl) 2002-08-30
EP0777671A1 (de) 1997-06-11
HUT77352A (hu) 1998-03-30
SA95160370B1 (ar) 2006-06-04
JPH10504561A (ja) 1998-05-06
US6051581A (en) 2000-04-18
US5902814A (en) 1999-05-11
CN1099419C (zh) 2003-01-22
AU690735B2 (en) 1998-04-30
IS4424A (is) 1997-02-03
ATE192157T1 (de) 2000-05-15
TR199501053A2 (tr) 1996-06-21
EP0777671B1 (de) 2000-04-26
CZ289512B6 (cs) 2002-02-13
CN1159808A (zh) 1997-09-17
HK1010370A1 (en) 1999-06-17
PT777671E (pt) 2000-08-31
DE69516524T2 (de) 2001-01-18
EE9700039A (et) 1997-08-15
KR100366331B1 (ko) 2003-04-10
CN1056846C (zh) 2000-09-27
TW397837B (en) 2000-07-11
CA2196995A1 (en) 1996-02-29
IS1852B (is) 2003-02-21
NO307707B1 (no) 2000-05-15
FI970762A (fi) 1997-02-24
DK0777671T3 (da) 2000-07-24
AR031828A2 (es) 2003-10-08
RU2148058C1 (ru) 2000-04-27
CN1284505A (zh) 2001-02-21
NZ292289A (en) 1998-05-27
SK21697A3 (en) 1997-09-10
JP3708962B2 (ja) 2005-10-19
NO970800L (no) 1997-02-21
NO970800D0 (no) 1997-02-21
BR9508751A (pt) 1997-08-12
CA2196995C (en) 2008-05-13
GR3033878T3 (en) 2000-11-30

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