DE69528825D1 - Dendrime verbindungen - Google Patents
Dendrime verbindungenInfo
- Publication number
- DE69528825D1 DE69528825D1 DE69528825T DE69528825T DE69528825D1 DE 69528825 D1 DE69528825 D1 DE 69528825D1 DE 69528825 T DE69528825 T DE 69528825T DE 69528825 T DE69528825 T DE 69528825T DE 69528825 D1 DE69528825 D1 DE 69528825D1
- Authority
- DE
- Germany
- Prior art keywords
- dendrime
- connections
- dendrime connections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
- A61K51/065—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules conjugates with carriers being macromolecules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G79/00—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/16—Dendrimers and dendritic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9407812A GB9407812D0 (en) | 1994-04-20 | 1994-04-20 | Compounds |
PCT/GB1995/000898 WO1995028966A1 (en) | 1994-04-20 | 1995-04-20 | Dendrimeric compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69528825D1 true DE69528825D1 (de) | 2002-12-19 |
DE69528825T2 DE69528825T2 (de) | 2003-09-11 |
Family
ID=10753821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69528825T Expired - Fee Related DE69528825T2 (de) | 1994-04-20 | 1995-04-20 | Dendrime verbindungen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5834020A (de) |
EP (1) | EP0756496B1 (de) |
JP (1) | JPH09512264A (de) |
CN (1) | CN1150391A (de) |
AU (1) | AU2263195A (de) |
CA (1) | CA2187921A1 (de) |
DE (1) | DE69528825T2 (de) |
GB (2) | GB9407812D0 (de) |
WO (1) | WO1995028966A1 (de) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6713045B1 (en) | 1995-06-02 | 2004-03-30 | Research Corporation Technologies, Inc. | Targeted magnetic resonance imaging agents for the detection of physiological processes |
US6770261B2 (en) | 1995-06-02 | 2004-08-03 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
DE19525924A1 (de) | 1995-07-04 | 1997-01-09 | Schering Ag | Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
US6166200A (en) * | 1995-07-04 | 2000-12-26 | Schering Aktiengesellschaft | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes |
US5874061A (en) * | 1995-12-22 | 1999-02-23 | Schering Aktiengesellschaft | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes |
DE19549286A1 (de) * | 1995-12-22 | 1997-06-26 | Schering Ag | Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
US5900228A (en) | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
AU3880097A (en) | 1996-08-14 | 1998-03-06 | Warner-Lambert Company | Low molecular weight dendritic compounds as pharmaceutical agents |
US20060008494A1 (en) * | 1997-02-21 | 2006-01-12 | The Regents Of The University Of California | Complete inactivation of infectious proteins |
US6719988B2 (en) | 1997-02-21 | 2004-04-13 | The Regents Of The University Of California | Antiseptic compositions for inactivating prions |
US6720355B2 (en) * | 1997-02-21 | 2004-04-13 | The Regents Of The University Of California | Sodium dodecyl sulfate compositions for inactivating prions |
US6419916B1 (en) | 1999-06-01 | 2002-07-16 | The Regents Of The University Of California | Assay for compounds which affect conformationally altered proteins |
US6331296B1 (en) * | 1999-06-01 | 2001-12-18 | Stanley B. Prusiner | Food additives which affect conformationally altered proteins |
US6322802B1 (en) | 1999-06-01 | 2001-11-27 | The Regents Of The University Of California | Method of sterilizing |
US6214366B1 (en) * | 1999-06-01 | 2001-04-10 | The Regents Of The University Of California | Clearance and inhibition of conformationally altered proteins |
DE19743373A1 (de) * | 1997-09-30 | 1999-04-15 | Univ Heidelberg | ·3··2·P-Polyphosphazen |
US6713046B1 (en) | 1997-10-27 | 2004-03-30 | Research Corporation Technologies | Magnetic resonance imaging agents for the delivery of therapeutic agents |
CA2309749A1 (en) * | 1997-11-17 | 1999-05-27 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
US6310043B1 (en) | 1998-08-07 | 2001-10-30 | Governors Of The University Of Alberta | Treatment of bacterial infections |
US5962423A (en) * | 1998-08-07 | 1999-10-05 | The Governors Of The University Of Alberta | Treatment of bacterial dysentery |
US6143080A (en) * | 1999-02-02 | 2000-11-07 | Silicon Valley Group Thermal Systems Llc | Wafer processing reactor having a gas flow control system and method |
AU5048400A (en) * | 1999-05-27 | 2000-12-18 | Monsanto Company | Biomaterials modified with superoxide dismutase mimics |
AU771547B2 (en) * | 1999-06-01 | 2004-03-25 | Regents Of The University Of California, The | Method of sterilizing |
CZ2002343A3 (cs) | 1999-07-29 | 2002-08-14 | Epix Medical, Inc. | Cílená multimerní zobrazovací činidla s multilokální vazebnou schopností |
US7067111B1 (en) | 1999-10-25 | 2006-06-27 | Board Of Regents, University Of Texas System | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging |
IT1317862B1 (it) | 2000-02-29 | 2003-07-15 | Bracco Spa | Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso. |
ATE350077T1 (de) | 2000-04-11 | 2007-01-15 | Polyzenix Gmbh | Verwendung von folien aus poly-tri-fluor- ethoxypolyphosphazenen zur umhüllung von medizinischen vorrichtungen |
US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
ATE374795T1 (de) * | 2000-06-12 | 2007-10-15 | Sumation Co Ltd | Elektrolumineszierende materialien und gegenstände aus einer polymermatrix |
US8206838B2 (en) * | 2000-06-12 | 2012-06-26 | Sumitomo Chemical Co., Ltd. | Polymer matrix electroluminescent materials and devices |
AU2001276956A1 (en) | 2000-07-17 | 2002-01-30 | California Institute Of Technology | Macrocyclic mri contrast agents |
US6690962B2 (en) * | 2000-09-15 | 2004-02-10 | Institut fur Diagnostikforshung GmbH | Process for graphic visualization and diagnosis of thrombi by means of nuclear spin tomography with use of particulate contrast media |
DE10048417A1 (de) * | 2000-09-29 | 2002-04-11 | Roche Diagnostics Gmbh | Verbindungen mit verzweigtem Linker |
AU2002211517A1 (en) | 2000-10-04 | 2002-04-15 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
US9080146B2 (en) | 2001-01-11 | 2015-07-14 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
EP1610751A4 (de) * | 2001-04-26 | 2006-05-24 | Univ Texas | Therapeutisches mittel/ligand-konjugat-zusammensetzungen, ihre syntheseverfahren und ihre anwendung |
US20050019267A1 (en) * | 2001-06-25 | 2005-01-27 | Brechbiel Martin W | Macromolecular imaging agents for liver imaging |
TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
US6905813B2 (en) * | 2001-08-29 | 2005-06-14 | Chugai Photo Chemical Co., Ltd. | Processing agent for silver halide color photosensitive material and processing method thereof |
US7261875B2 (en) | 2001-12-21 | 2007-08-28 | Board Of Regents, The University Of Texas System | Dendritic poly (amino acid) carriers and methods of use |
AU2003210755A1 (en) * | 2002-02-01 | 2003-09-02 | Vanderbilt University | Targeted drug delivery methods |
US6852842B2 (en) * | 2002-08-26 | 2005-02-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for functional kidney imaging using small dendrimer contrast agents |
AU2003299140B2 (en) | 2002-09-24 | 2008-07-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for convection enhanced delivery of therapeutic agents |
US20040180852A1 (en) * | 2003-03-10 | 2004-09-16 | Cara-Lynne Schengrund | Use of multivalent glycodendrimers to inhibit the activity of human immunodeficiency virus |
US20040258614A1 (en) * | 2003-06-20 | 2004-12-23 | University Of Maryland, Baltimore | Microparticles for microarterial imaging and radiotherapy |
US20050085417A1 (en) * | 2003-10-16 | 2005-04-21 | Thomas Jefferson University | Compounds and methods for diagnostic imaging and therapy |
US9050378B2 (en) | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
US7199268B2 (en) | 2003-12-16 | 2007-04-03 | Schering Aktiengesellschaft | Process for the production of dendritic trimesic acid triamides |
US20050171424A1 (en) * | 2004-01-13 | 2005-08-04 | The Gov. Of The Usa As Rep. By The Secretary Of The Dept. Of Health And Human Services | Methods for imaging the lymphatic system using dendrimer-based contrast agents |
CN1997671B (zh) * | 2004-06-14 | 2012-07-18 | 诺和诺德公司 | 通过硬金属离子亲和层析法的肽纯化 |
US7671033B2 (en) * | 2004-07-01 | 2010-03-02 | The Trustees Of The University Of Pennsylvania | Amphiphilic dendritic dipeptides and their self-assembly into helical pores |
US20210299056A9 (en) | 2004-10-25 | 2021-09-30 | Varian Medical Systems, Inc. | Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods |
US9114162B2 (en) | 2004-10-25 | 2015-08-25 | Celonova Biosciences, Inc. | Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same |
US9107850B2 (en) | 2004-10-25 | 2015-08-18 | Celonova Biosciences, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
US20060204443A1 (en) * | 2005-03-11 | 2006-09-14 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Methods for tumor treatment using dendrimer conjugates |
WO2006125965A1 (en) * | 2005-05-21 | 2006-11-30 | University Of Durham | Novel surface active polymeric systems |
ES2265291B1 (es) * | 2005-07-22 | 2008-03-01 | Universidad De Alcala | Nuevos dendrimeros carbosilanos, su preparacion y sus usos. |
PL1937284T3 (pl) | 2005-10-18 | 2016-05-31 | Starpharma Pty Ltd | System podawania kompozycji bakteriobójczego dendymeru |
PT1940916T (pt) | 2005-10-25 | 2017-03-20 | Starpharma Pty Ltd | Composto macromolecular tendo estequiometria controlada |
CA2636599C (en) * | 2006-01-20 | 2014-07-15 | Starpharma Pty Limited | Modified macromolecule |
US8263103B2 (en) * | 2006-01-31 | 2012-09-11 | Boston Scientific Scimed, Inc. | Medical articles containing biodegradable polymers and acid-neutralizing cationic species |
AU2007229268B2 (en) | 2006-03-22 | 2013-01-10 | Starpharma Pty Limited | Contraceptive composition |
DK2052011T3 (da) | 2006-08-11 | 2020-12-07 | Starpharma Pty Ltd | Målrettet polylysin-dendrimer-terapeutisk stof |
US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
ES2378905T3 (es) | 2006-10-10 | 2012-04-19 | Celonova Biosciences, Inc. | Válvula cardiaca bioprotésica con polifosfaceno |
US20080190921A1 (en) * | 2007-02-08 | 2008-08-14 | The Evercare Company | Clothes hamper |
US9096849B2 (en) * | 2007-05-21 | 2015-08-04 | The United States Of America, As Represented By The Secretary Of The Navy | Solid phase for capture of nucleic acids |
US8303937B2 (en) | 2007-12-31 | 2012-11-06 | Industrial Technology Research Institute | Dendritic polymers and magnetic resonance imaging contrast agent employing the same |
US8252834B2 (en) | 2008-03-12 | 2012-08-28 | The Regents Of The University Of Michigan | Dendrimer conjugates |
US8889635B2 (en) | 2008-09-30 | 2014-11-18 | The Regents Of The University Of Michigan | Dendrimer conjugates |
WO2010054321A2 (en) | 2008-11-07 | 2010-05-14 | The Regents Of The University Of Michigan | Methods of treating autoimmune disorders and/or inflammatory disorders |
EP2430058A4 (de) * | 2009-05-12 | 2013-03-06 | Chemnano Materials Ltd | Schwefelfunktionalisierte polymere zur trennung von metallen von gas und flüssigkeit sowie herstellungsverfahren dafür |
AU2010318637A1 (en) | 2009-10-13 | 2012-05-31 | The Regents Of The University Of Michigan | Dendrimer compositions and methods of synthesis |
US9585387B1 (en) | 2009-10-26 | 2017-03-07 | Starpharma Pty Ltd | PEHAM dendrimers for use in agriculture |
CN102781231B (zh) * | 2009-10-26 | 2014-12-24 | 德瑞迪克纳米科技公司 | 用于农业中的peham树枝状化合物 |
US8912323B2 (en) | 2009-10-30 | 2014-12-16 | The Regents Of The University Of Michigan | Multifunctional small molecules |
US8592628B2 (en) | 2010-06-03 | 2013-11-26 | Battelle Energy Alliance, Llc | Phosphazene additives |
KR101334780B1 (ko) * | 2010-08-13 | 2013-12-02 | 한국생명공학연구원 | 요오드를 함유한 방사형상의 고분자 화합물, 이의 제조방법 및 이를 포함하는 ct용 조영제 조성물 |
CN101974029B (zh) * | 2010-10-29 | 2012-07-04 | 河南科技学院 | 一种制备磷酸乙醇胺化合物的方法 |
WO2012162789A1 (en) * | 2011-06-01 | 2012-12-06 | University Of British Columbia | Polymers for reversing heparin-based anticoagulation |
US9402911B2 (en) | 2011-12-08 | 2016-08-02 | The Regents Of The University Of Michigan | Multifunctional small molecules |
WO2013086396A1 (en) | 2011-12-09 | 2013-06-13 | Ikaria Development Subsidiary One Llc | Labeled alginate conjugates for molecular imaging applications |
CN103804418A (zh) * | 2014-03-13 | 2014-05-21 | 中国科学院福建物质结构研究所 | 一类可降解药物载体材料的制备及用途 |
WO2021100042A1 (en) * | 2019-11-18 | 2021-05-27 | Technion Research & Development Foundation Limited | Minimally-invasive continuous clinical monitoring of small molecules with analytical accuracy |
WO2024083224A1 (en) * | 2022-10-20 | 2024-04-25 | Full-Life Technologies Hk Limited | Dual receptor targeting radioligands and uses thereof related applications |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338532A (en) * | 1986-08-18 | 1994-08-16 | The Dow Chemical Company | Starburst conjugates |
DE3786000T3 (de) * | 1986-08-18 | 1997-08-21 | Dow Chemical Co | Conjugate dichter Sterne. |
US5914095A (en) * | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
US5364613A (en) * | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
DK0429644T3 (da) * | 1989-05-26 | 1996-01-22 | Ramaswamy Subramanian | Chelat-dannende midler til binding af metalioner til proteiner |
US5157095A (en) * | 1989-11-09 | 1992-10-20 | The Research Foundation Of State University Of New York | Hydrosilylation of unsaturated aliphatic isocyanates |
DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
JPH03263431A (ja) * | 1990-03-13 | 1991-11-22 | Kao Corp | ケイ素含有デンドリマー |
GB9006977D0 (en) * | 1990-03-28 | 1990-05-23 | Nycomed As | Compositions |
-
1994
- 1994-04-20 GB GB9407812A patent/GB9407812D0/en active Pending
- 1994-10-13 GB GB9420657A patent/GB9420657D0/en active Pending
-
1995
- 1995-04-20 CN CN95193094A patent/CN1150391A/zh active Pending
- 1995-04-20 DE DE69528825T patent/DE69528825T2/de not_active Expired - Fee Related
- 1995-04-20 JP JP7527454A patent/JPH09512264A/ja not_active Ceased
- 1995-04-20 CA CA002187921A patent/CA2187921A1/en not_active Abandoned
- 1995-04-20 AU AU22631/95A patent/AU2263195A/en not_active Abandoned
- 1995-04-20 US US08/722,082 patent/US5834020A/en not_active Expired - Lifetime
- 1995-04-20 EP EP95915939A patent/EP0756496B1/de not_active Expired - Lifetime
- 1995-04-20 WO PCT/GB1995/000898 patent/WO1995028966A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CN1150391A (zh) | 1997-05-21 |
EP0756496A1 (de) | 1997-02-05 |
JPH09512264A (ja) | 1997-12-09 |
WO1995028966A1 (en) | 1995-11-02 |
US5834020A (en) | 1998-11-10 |
CA2187921A1 (en) | 1995-11-02 |
GB9407812D0 (en) | 1994-06-15 |
DE69528825T2 (de) | 2003-09-11 |
GB9420657D0 (en) | 1994-11-30 |
AU2263195A (en) | 1995-11-16 |
EP0756496B1 (de) | 2002-11-13 |
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FI1465U1 (fi) | Hjaelpmedel foer skorning av en haest | |
FI1448U1 (fi) | Anordning foer synkronisering av musiktempon | |
FI1864U1 (fi) | Faestanordning av skoputsningsapparatens putsborste | |
FI1792U1 (fi) | Anordning foer oeppnande av en vaetskebehaollares proppar | |
FI1778U1 (fi) | Speciellt foer moebelindustrins bruk laemlig lamellrad skiva av massivtrae | |
FI1771U1 (fi) | Anordning foer maskinell omblandning av stroeunderlag | |
FI1758U1 (fi) | Anordning foer maetning av muskelkraft | |
FI1473U1 (fi) | Anordning foer producering av vaerme | |
FI1673U1 (fi) | Anordning foer hantering av varor | |
FI1663U1 (fi) | Upplyftled av roderbad |
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