DE69511861D1 - Verfahren zur entfernung von gallsaüre von einem patienten sowie die alkylierte zusammensetzungen dafür - Google Patents

Verfahren zur entfernung von gallsaüre von einem patienten sowie die alkylierte zusammensetzungen dafür

Info

Publication number
DE69511861D1
DE69511861D1 DE69511861T DE69511861T DE69511861D1 DE 69511861 D1 DE69511861 D1 DE 69511861D1 DE 69511861 T DE69511861 T DE 69511861T DE 69511861 T DE69511861 T DE 69511861T DE 69511861 D1 DE69511861 D1 DE 69511861D1
Authority
DE
Germany
Prior art keywords
patient
reaction product
alkylating agent
gallic acid
ch2ch2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69511861T
Other languages
English (en)
Other versions
DE69511861T2 (de
DE122004000034I2 (de
Inventor
W Mandeville
Stephen Holmes-Farley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geltex Pharmaceuticals Inc
Original Assignee
Geltex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22980525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69511861(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geltex Pharmaceuticals Inc filed Critical Geltex Pharmaceuticals Inc
Publication of DE69511861D1 publication Critical patent/DE69511861D1/de
Application granted granted Critical
Publication of DE69511861T2 publication Critical patent/DE69511861T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/02Alkylation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • C08L39/02Homopolymers or copolymers of vinylamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69511861T 1994-06-10 1995-06-05 Verfahren zur entfernung von gallsaüre von einem patienten sowie die alkylierte zusammensetzungen dafür Expired - Lifetime DE69511861T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25843194A 1994-06-10 1994-06-10
PCT/US1995/007181 WO1995034585A1 (en) 1994-06-10 1995-06-05 Process for removing bile salts from a patient and alkylated compositions therefor

Publications (2)

Publication Number Publication Date
DE69511861D1 true DE69511861D1 (de) 1999-10-07
DE69511861T2 DE69511861T2 (de) 2000-02-10

Family

ID=22980525

Family Applications (3)

Application Number Title Priority Date Filing Date
DE200412000034 Pending DE122004000034I1 (de) 1994-06-10 1995-06-05 Verfahren zur entfernung von Gallsa}re von einem Patienten sowie die alkylierte zusammensetzungen dafür.
DE1995611861 Active DE122004000034I2 (de) 1994-06-10 1995-06-05 Verfahren zur entfernung von Gallsaure von einem Patienten sowie alkylierte zusammensetzungen dafür
DE69511861T Expired - Lifetime DE69511861T2 (de) 1994-06-10 1995-06-05 Verfahren zur entfernung von gallsaüre von einem patienten sowie die alkylierte zusammensetzungen dafür

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE200412000034 Pending DE122004000034I1 (de) 1994-06-10 1995-06-05 Verfahren zur entfernung von Gallsa}re von einem Patienten sowie die alkylierte zusammensetzungen dafür.
DE1995611861 Active DE122004000034I2 (de) 1994-06-10 1995-06-05 Verfahren zur entfernung von Gallsaure von einem Patienten sowie alkylierte zusammensetzungen dafür

Country Status (21)

Country Link
US (12) US5693675A (de)
EP (2) EP0909768A3 (de)
JP (1) JP3931217B2 (de)
KR (1) KR100271693B1 (de)
CN (1) CN1150217C (de)
AT (1) ATE184027T1 (de)
AU (1) AU698752C (de)
CA (1) CA2191478C (de)
DE (3) DE122004000034I1 (de)
DK (1) DK0764174T3 (de)
ES (1) ES2135743T3 (de)
FR (1) FR04C0021I2 (de)
GR (1) GR3031702T3 (de)
IL (2) IL114073A (de)
LU (1) LU91100I2 (de)
MX (1) MX9606171A (de)
NL (1) NL300159I2 (de)
NZ (1) NZ288076A (de)
RU (1) RU2160742C2 (de)
TW (1) TW474813B (de)
WO (1) WO1995034585A1 (de)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
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US6225355B1 (en) 2001-05-01
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DE69511861T2 (de) 2000-02-10
ATE184027T1 (de) 1999-09-15
LU91100I9 (de) 2019-01-29
US20070155950A1 (en) 2007-07-05
AU698752C (en) 2002-08-08
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