ES2107562T3 - Amidas de acidos alfa-aril-alfa-hidroxi-beta-imidazolinil-propanoicos. - Google Patents

Amidas de acidos alfa-aril-alfa-hidroxi-beta-imidazolinil-propanoicos.

Info

Publication number
ES2107562T3
ES2107562T3 ES93100273T ES93100273T ES2107562T3 ES 2107562 T3 ES2107562 T3 ES 2107562T3 ES 93100273 T ES93100273 T ES 93100273T ES 93100273 T ES93100273 T ES 93100273T ES 2107562 T3 ES2107562 T3 ES 2107562T3
Authority
ES
Spain
Prior art keywords
alpha
aryl
hydroxy
imidazolinyl
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93100273T
Other languages
English (en)
Inventor
Wilfried Dr Draber
Hilmar Dr Bischoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2107562T3 publication Critical patent/ES2107562T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION PRESENTADA CONCIERNE A NUEVA AMIDAS DEL ACIDO O ARIL FORMULA GENERAL (I), EN LA CUAL N, R1 A R4 Y X TIENEN LOS SIGNIFICADOS DADOS EN LA DESCRIPCION, UN PROCEDIMIENTO PARA SU OBTENCION Y SU UTILIZACION EN MEDICAMENTOS.
ES93100273T 1992-01-23 1993-01-11 Amidas de acidos alfa-aril-alfa-hidroxi-beta-imidazolinil-propanoicos. Expired - Lifetime ES2107562T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4201709A DE4201709A1 (de) 1992-01-23 1992-01-23 (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide

Publications (1)

Publication Number Publication Date
ES2107562T3 true ES2107562T3 (es) 1997-12-01

Family

ID=6450062

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93100273T Expired - Lifetime ES2107562T3 (es) 1992-01-23 1993-01-11 Amidas de acidos alfa-aril-alfa-hidroxi-beta-imidazolinil-propanoicos.

Country Status (22)

Country Link
US (1) US5334610A (es)
EP (1) EP0552631B1 (es)
JP (1) JPH05286942A (es)
KR (1) KR930016401A (es)
CN (1) CN1075714A (es)
AT (1) ATE158576T1 (es)
AU (1) AU650807B2 (es)
CA (1) CA2087650A1 (es)
CZ (1) CZ282024B6 (es)
DE (2) DE4201709A1 (es)
DK (1) DK0552631T3 (es)
ES (1) ES2107562T3 (es)
GR (1) GR3025179T3 (es)
HU (1) HUT63394A (es)
IL (1) IL104444A (es)
MX (1) MX9300136A (es)
MY (1) MY108826A (es)
NZ (1) NZ245726A (es)
PL (1) PL172005B1 (es)
SK (1) SK372292A3 (es)
TW (1) TW232011B (es)
ZA (1) ZA93477B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
US7439383B2 (en) 2002-04-18 2008-10-21 University Of Virginia Patent Foundation Sodium channel blockers
CA2508581A1 (en) * 2002-12-04 2004-06-17 Merck & Co., Inc. Spirocyclic ureas, compositions containing such compounds and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7605958L (sv) * 1975-05-30 1976-12-01 Scherico Ltd Nya 2-imidazoliner och deras anvendning sasom hypoglykemiska medel
DE2614240C3 (de) * 1976-04-02 1980-03-06 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Acylcyaniden
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
US4136188A (en) * 1976-06-25 1979-01-23 Daiichi Seiyaku Co., Ltd. Treatment of diabetes with 2-substituted-1,3-diazacyclic compounds
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Also Published As

Publication number Publication date
CA2087650A1 (en) 1993-07-24
ZA93477B (en) 1993-08-23
ATE158576T1 (de) 1997-10-15
DE4201709A1 (de) 1993-07-29
SK278548B6 (en) 1997-09-10
PL297491A1 (en) 1993-08-09
IL104444A (en) 1997-06-10
CZ372292A3 (en) 1993-12-15
HU9300181D0 (en) 1993-04-28
EP0552631B1 (de) 1997-09-24
PL172005B1 (pl) 1997-07-31
JPH05286942A (ja) 1993-11-02
DK0552631T3 (da) 1998-05-11
EP0552631A1 (de) 1993-07-28
CN1075714A (zh) 1993-09-01
IL104444A0 (en) 1993-05-13
DE59307401D1 (de) 1997-10-30
CZ282024B6 (cs) 1997-04-16
SK372292A3 (en) 1997-09-10
NZ245726A (en) 1996-01-26
GR3025179T3 (en) 1998-02-27
TW232011B (es) 1994-10-11
MY108826A (en) 1996-11-30
MX9300136A (es) 1993-07-01
US5334610A (en) 1994-08-02
KR930016401A (ko) 1993-08-26
AU3188893A (en) 1993-07-29
HUT63394A (en) 1993-08-30
AU650807B2 (en) 1994-06-30

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