DE69508791T2 - Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer - Google Patents

Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Info

Publication number
DE69508791T2
DE69508791T2 DE69508791T DE69508791T DE69508791T2 DE 69508791 T2 DE69508791 T2 DE 69508791T2 DE 69508791 T DE69508791 T DE 69508791T DE 69508791 T DE69508791 T DE 69508791T DE 69508791 T2 DE69508791 T2 DE 69508791T2
Authority
DE
Germany
Prior art keywords
17beta
administrating
intravaginal device
oestradiol precursors
oestradiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69508791T
Other languages
English (en)
Other versions
DE69508791D1 (de
Inventor
Allen Mcclay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Ireland Ltd
Original Assignee
Galen Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galen Chemicals Ltd filed Critical Galen Chemicals Ltd
Application granted granted Critical
Publication of DE69508791D1 publication Critical patent/DE69508791D1/de
Publication of DE69508791T2 publication Critical patent/DE69508791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69508791T 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer Expired - Lifetime DE69508791T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IES940976 1994-12-19
IES950247 1995-04-05
PCT/IE1995/000063 WO1996019196A1 (en) 1994-12-19 1995-12-19 INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS

Publications (2)

Publication Number Publication Date
DE69508791D1 DE69508791D1 (de) 1999-05-06
DE69508791T2 true DE69508791T2 (de) 1999-12-02

Family

ID=26319777

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69508791T Expired - Lifetime DE69508791T2 (de) 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Country Status (19)

Country Link
US (1) US5855906A (de)
EP (1) EP0799025B1 (de)
JP (1) JPH10510825A (de)
CN (1) CN1138526C (de)
AR (1) AR002010A1 (de)
AT (1) ATE178204T1 (de)
AU (1) AU692659B2 (de)
CA (1) CA2207622C (de)
DE (1) DE69508791T2 (de)
DK (1) DK0799025T3 (de)
ES (1) ES2133841T3 (de)
FI (1) FI119414B (de)
GR (1) GR3030614T3 (de)
IL (1) IL116433A (de)
NO (1) NO316707B1 (de)
NZ (1) NZ298490A (de)
PE (1) PE62796A1 (de)
TR (1) TR199501599A2 (de)
WO (1) WO1996019196A1 (de)

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US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
CN1184957C (zh) * 1997-05-07 2005-01-19 盖伦(化学制品)有限公司 用于给药睾酮和睾酮前体的阴道内给药装置
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6811549B2 (en) * 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US6962908B2 (en) * 2001-12-21 2005-11-08 Warner Chilcott Company Inc. Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
WO2003080018A1 (en) * 2002-03-27 2003-10-02 Galen (Chemicals) Limited Intravaginal matrix drug delivery devices
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
ATE461681T1 (de) * 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
WO2006084083A2 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Devices for delivering agents to a vaginal tract
EP1853272A1 (de) * 2005-02-03 2007-11-14 Duramed Pharmaceuticals, Inc. Zusammensetzungen aus unkonjugierten östrogenen und anwendungsverfahren dafür
CA2618349C (en) * 2005-08-11 2016-05-31 Massachusetts Institute Of Technology Intravesical drug delivery device and method
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
WO2007047420A2 (en) * 2005-10-13 2007-04-26 Synthes (U.S.A.) Drug-impregnated encasement
GB0613333D0 (en) * 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
BRPI0713203A2 (pt) * 2006-07-12 2012-04-03 Controlled Therapeutics Scotland Ltda inserto, métodos, embalagem, dispositivo recuperável e dispositivo inserìvel
GB0620685D0 (en) * 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
WO2009003125A1 (en) 2007-06-26 2008-12-31 Warner Chilcott Company,Inc. Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs
CN101896221B (zh) * 2007-12-11 2013-06-05 麻省理工学院 用于治疗膀胱和其它体囊或体腔的可植入式药物递送设备和方法
CN102176931B (zh) * 2008-08-09 2015-03-04 麻省理工学院 治疗男性泌尿生殖组织和外周组织的可植入药物递送设备和方法
EP4108216A1 (de) 2009-06-03 2022-12-28 Forsight Vision5, Inc. Wirkstofffreisetzung im vorderen augensegment
CN102470237A (zh) 2009-06-26 2012-05-23 塔里斯生物医药公司 用于可植入药物递送装置的固体药物片剂
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8939948B2 (en) 2010-06-01 2015-01-27 Forsight Vision5, Inc. Ocular insert apparatus and methods
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
JP2014503554A (ja) 2011-01-10 2014-02-13 タリス バイオメディカル，インコーポレイテッド 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン
WO2012106714A1 (en) 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
PT2911623T (pt) 2012-10-26 2019-11-21 Forsight Vision5 Inc Sistema oftálmico para libertação prolongada de fármaco no olho
AU2014232801B2 (en) 2013-03-15 2019-01-17 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
EP3010560B1 (de) 2013-06-21 2020-01-01 DePuy Synthes Products, Inc. Folien und verfahren zur herstellung
RS60847B1 (sr) 2013-08-19 2020-10-30 Taris Biomedical Llc Uređaji za davanje više jedinica leka
CN104546668B (zh) * 2013-10-23 2019-03-05 国家卫生计生委科学技术研究所 液体硅橡胶为载体的药物缓控释系统的制备及应用
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
CN106456838B (zh) * 2014-04-01 2020-12-29 保利医学公司 避孕装置及相关装置
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
EP3285850A1 (de) 2015-04-23 2018-02-28 TARIS Biomedical LLC Wirkstoffabgabevorrichtungen mit einer wirkstoffdurchlässigen komponente und verfahren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4291014A (en) * 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
SE8602666D0 (sv) * 1986-06-16 1986-06-16 Leo Ab Intravaginal devices

Also Published As

Publication number Publication date
WO1996019196A1 (en) 1996-06-27
NO972798D0 (no) 1997-06-17
FI119414B (fi) 2008-11-14
DK0799025T3 (da) 1999-10-18
ATE178204T1 (de) 1999-04-15
IL116433A (en) 2002-02-10
CN1170353A (zh) 1998-01-14
EP0799025B1 (de) 1999-03-31
PE62796A1 (es) 1996-12-28
AR002010A1 (es) 1998-01-07
NO972798L (no) 1997-08-19
FI972579A (fi) 1997-06-17
NZ298490A (en) 1999-11-29
CN1138526C (zh) 2004-02-18
JPH10510825A (ja) 1998-10-20
IL116433A0 (en) 1996-03-31
ES2133841T3 (es) 1999-09-16
US5855906A (en) 1999-01-05
GR3030614T3 (en) 1999-10-29
AU4399196A (en) 1996-07-10
AU692659B2 (en) 1998-06-11
DE69508791D1 (de) 1999-05-06
EP0799025A1 (de) 1997-10-08
TR199501599A2 (tr) 1996-07-21
FI972579A0 (fi) 1997-06-17
CA2207622A1 (en) 1996-06-27
NO316707B1 (no) 2004-04-13
CA2207622C (en) 2006-10-17

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