DE69434261D1 - Verfahren und Vorrichtung zur Ejektion von unerwünschten Ionen aus einem Ionenfallemassenspektrometer - Google Patents

Verfahren und Vorrichtung zur Ejektion von unerwünschten Ionen aus einem Ionenfallemassenspektrometer

Info

Publication number
DE69434261D1
DE69434261D1 DE69434261T DE69434261T DE69434261D1 DE 69434261 D1 DE69434261 D1 DE 69434261D1 DE 69434261 T DE69434261 T DE 69434261T DE 69434261 T DE69434261 T DE 69434261T DE 69434261 D1 DE69434261 D1 DE 69434261D1
Authority
DE
Germany
Prior art keywords
ejection
mass spectrometer
ion trap
trap mass
unwanted ions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69434261T
Other languages
English (en)
Other versions
DE69434261T2 (de
Inventor
John Nathan Louris
Dennis Milton Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Thermo Finnigan LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Finnigan LLC filed Critical Thermo Finnigan LLC
Application granted granted Critical
Publication of DE69434261D1 publication Critical patent/DE69434261D1/de
Publication of DE69434261T2 publication Critical patent/DE69434261T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426—Methods for controlling ions
    • H01J49/427—Ejection and selection methods
    • H01J49/428—Applying a notched broadband signal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
DE69434261T 1993-05-28 1994-04-08 Verfahren und Vorrichtung zur Ejektion von unerwünschten Ionen aus einem Ionenfallemassenspektrometer Expired - Lifetime DE69434261T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/068,915 US5324939A (en) 1993-05-28 1993-05-28 Method and apparatus for ejecting unwanted ions in an ion trap mass spectrometer
US68915 1993-05-28

Publications (2)

Publication Number Publication Date
DE69434261D1 true DE69434261D1 (de) 2005-03-17
DE69434261T2 DE69434261T2 (de) 2006-03-23

Family

ID=22085529

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434261T Expired - Lifetime DE69434261T2 (de) 1993-05-28 1994-04-08 Verfahren und Vorrichtung zur Ejektion von unerwünschten Ionen aus einem Ionenfallemassenspektrometer

Country Status (5)

Country Link
US (1) US5324939A (de)
EP (1) EP0626719B1 (de)
JP (1) JP2703724B2 (de)
CA (1) CA2120401C (de)
DE (1) DE69434261T2 (de)

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US5449905A (en) * 1992-05-14 1995-09-12 Teledyne Et Method for generating filtered noise signal and broadband signal having reduced dynamic range for use in mass spectrometry
US5479012A (en) * 1992-05-29 1995-12-26 Varian Associates, Inc. Method of space charge control in an ion trap mass spectrometer
DE19501823A1 (de) * 1995-01-21 1996-07-25 Bruker Franzen Analytik Gmbh Verfahren zur Regelung der Erzeugungsraten für massenselektives Einspeichern von Ionen in Ionenfallen
DE19501835C2 (de) * 1995-01-21 1998-07-02 Bruker Franzen Analytik Gmbh Verfahren zur Anregung der Schwingungen von Ionen in Ionenfallen mit Frequenzgemischen
US5696376A (en) * 1996-05-20 1997-12-09 The Johns Hopkins University Method and apparatus for isolating ions in an ion trap with increased resolving power
JP3413079B2 (ja) * 1997-10-09 2003-06-03 株式会社日立製作所 イオントラップ型質量分析装置
US6124591A (en) 1998-10-16 2000-09-26 Finnigan Corporation Method of ion fragmentation in a quadrupole ion trap
US6911650B1 (en) * 1999-08-13 2005-06-28 Bruker Daltonics, Inc. Method and apparatus for multiple frequency multipole
CA2307399C (en) 2000-05-02 2006-10-03 Mds Inc., Doing Business As Mds Sciex Method for reducing chemical background in mass spectra
US6627883B2 (en) 2001-03-02 2003-09-30 Bruker Daltonics Inc. Apparatus and method for analyzing samples in a dual ion trap mass spectrometer
US6627875B2 (en) * 2001-04-23 2003-09-30 Beyond Genomics, Inc. Tailored waveform/charge reduction mass spectrometry
JP3676298B2 (ja) * 2001-12-28 2005-07-27 三菱重工業株式会社 化学物質の検出装置および化学物質の検出方法
WO2005001465A1 (ja) * 2003-06-27 2005-01-06 Mitsubishi Heavy Industries, Ltd. 化学物質の検出装置および化学物質の検出方法
US6710336B2 (en) 2002-01-30 2004-03-23 Varian, Inc. Ion trap mass spectrometer using pre-calculated waveforms for ion isolation and collision induced dissociation
US20040119014A1 (en) * 2002-12-18 2004-06-24 Alex Mordehai Ion trap mass spectrometer and method for analyzing ions
WO2005024381A2 (en) * 2003-09-05 2005-03-17 Griffin Analytical Technologies, Inc. Analysis methods, analysis device waveform generation methods, analysis devices, and articles of manufacture
JP2005108578A (ja) * 2003-09-30 2005-04-21 Hitachi Ltd 質量分析装置
JP4200092B2 (ja) 2003-12-24 2008-12-24 株式会社日立ハイテクノロジーズ 質量分析装置及びそのキャリブレーション方法
WO2006002027A2 (en) * 2004-06-15 2006-01-05 Griffin Analytical Technologies, Inc. Portable mass spectrometer configured to perform multidimensional mass analysis
US7456396B2 (en) * 2004-08-19 2008-11-25 Thermo Finnigan Llc Isolating ions in quadrupole ion traps for mass spectrometry
US20060182014A1 (en) * 2005-02-14 2006-08-17 Texas Instruments Incorporated Apparatus for and method of characterization of ethernet cable impairments
US8680461B2 (en) 2005-04-25 2014-03-25 Griffin Analytical Technologies, L.L.C. Analytical instrumentation, apparatuses, and methods
US7372024B2 (en) * 2005-09-13 2008-05-13 Agilent Technologies, Inc. Two dimensional ion traps with improved ion isolation and method of use
US7378648B2 (en) * 2005-09-30 2008-05-27 Varian, Inc. High-resolution ion isolation utilizing broadband waveform signals
US7378653B2 (en) * 2006-01-10 2008-05-27 Varian, Inc. Increasing ion kinetic energy along axis of linear ion processing devices
US7351965B2 (en) * 2006-01-30 2008-04-01 Varian, Inc. Rotating excitation field in linear ion processing apparatus
US7405400B2 (en) * 2006-01-30 2008-07-29 Varian, Inc. Adjusting field conditions in linear ion processing apparatus for different modes of operation
US7405399B2 (en) * 2006-01-30 2008-07-29 Varian, Inc. Field conditions for ion excitation in linear ion processing apparatus
US7992424B1 (en) 2006-09-14 2011-08-09 Griffin Analytical Technologies, L.L.C. Analytical instrumentation and sample analysis methods
US7943899B2 (en) * 2006-12-21 2011-05-17 Thermo Finnigan Llc Method and apparatus for identifying the apex of a chromatographic peak
GB0701476D0 (en) * 2007-01-25 2007-03-07 Micromass Ltd Mass spectrometer
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US8598517B2 (en) * 2007-12-20 2013-12-03 Purdue Research Foundation Method and apparatus for activation of cation transmission mode ion/ion reactions
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
US8178835B2 (en) * 2009-05-07 2012-05-15 Thermo Finnigan Llc Prolonged ion resonance collision induced dissociation in a quadrupole ion trap
JP5333072B2 (ja) * 2009-09-03 2013-11-06 株式会社島津製作所 イオントラップ装置
WO2013022747A1 (en) * 2011-08-05 2013-02-14 Academia Sinica Step-scan ion trap mass spectrometry for high speed proteomics
GB201122267D0 (en) * 2011-12-23 2012-02-01 Micromass Ltd Multi-pass ion mobility separation device with moving exit aperture
US9048074B2 (en) 2012-01-24 2015-06-02 Thermo Finnigan Llc Multinotch isolation for MS3 mass analysis
CA2900739C (en) 2013-02-18 2019-08-27 Micromass Uk Limited Device allowing improved reaction monitoring of gas phase reactions in mass spectrometers using an auto ejection ion trap
WO2014164198A1 (en) * 2013-03-11 2014-10-09 David Rafferty Automatic gain control with defocusing lens
US8969794B2 (en) 2013-03-15 2015-03-03 1St Detect Corporation Mass dependent automatic gain control for mass spectrometer
US9117646B2 (en) * 2013-10-04 2015-08-25 Thermo Finnigan Llc Method and apparatus for a combined linear ion trap and quadrupole mass filter
EP3172760A1 (de) * 2014-07-25 2017-05-31 1st DETECT CORPORATION Massenspektrometer mit echtzeit-ionenisolationssignalgeneratoren
DE102015208188A1 (de) * 2015-05-04 2016-11-24 Carl Zeiss Smt Gmbh Verfahren zur massenspektrometrischen Untersuchung eines Gases und Massenspektrometer
US9818595B2 (en) 2015-05-11 2017-11-14 Thermo Finnigan Llc Systems and methods for ion isolation using a dual waveform
US9875885B2 (en) * 2015-05-11 2018-01-23 Thermo Finnigan Llc Systems and methods for ion isolation
EP3321953B1 (de) 2016-11-10 2019-06-26 Thermo Finnigan LLC Systeme und verfahren zur skalierung einer injektion-wellenformsamplitude während der ionenisolation
CN112444553B (zh) * 2019-08-12 2022-09-30 北京理工大学 一种用于提升微型质谱仪灵敏度和定量分析能力的方法和应用
CN112071737B (zh) * 2020-03-20 2024-04-16 昆山聂尔精密仪器有限公司 一种离子激发和离子选择信号的生成方法和装置

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5107109A (en) * 1986-03-07 1992-04-21 Finnigan Corporation Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer
US4761545A (en) * 1986-05-23 1988-08-02 The Ohio State University Research Foundation Tailored excitation for trapped ion mass spectrometry
US4818869A (en) * 1987-05-22 1989-04-04 Finnigan Corporation Method of isolating a single mass or narrow range of masses and/or enhancing the sensitivity of an ion trap mass spectrometer
EP0362432A1 (de) * 1988-10-07 1990-04-11 Bruker Franzen Analytik GmbH Methode zur Massenanalyse einer Probe
US4945234A (en) * 1989-05-19 1990-07-31 Extrel Ftms, Inc. Method and apparatus for producing an arbitrary excitation spectrum for Fourier transform mass spectrometry
US5013912A (en) * 1989-07-14 1991-05-07 University Of The Pacific General phase modulation method for stored waveform inverse fourier transform excitation for fourier transform ion cyclotron resonance mass spectrometry
US5134286A (en) * 1991-02-28 1992-07-28 Teledyne Cme Mass spectrometry method using notch filter
US5248882A (en) * 1992-05-28 1993-09-28 Extrel Ftms, Inc. Method and apparatus for providing tailored excitation as in Fourier transform mass spectrometry

Also Published As

Publication number Publication date
JP2703724B2 (ja) 1998-01-26
CA2120401C (en) 1999-02-23
EP0626719A2 (de) 1994-11-30
EP0626719B1 (de) 2005-02-09
US5324939A (en) 1994-06-28
DE69434261T2 (de) 2006-03-23
CA2120401A1 (en) 1994-11-29
EP0626719A3 (en) 1997-07-02
JPH0714540A (ja) 1995-01-17

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