DE69432511T2 - Protein p140 und dafür kodierende DNS - Google Patents
Protein p140 und dafür kodierende DNS Download PDFInfo
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- DE69432511T2 DE69432511T2 DE69432511T DE69432511T DE69432511T2 DE 69432511 T2 DE69432511 T2 DE 69432511T2 DE 69432511 T DE69432511 T DE 69432511T DE 69432511 T DE69432511 T DE 69432511T DE 69432511 T2 DE69432511 T2 DE 69432511T2
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- NISGSNTVMOOSJQ-UHFFFAOYSA-N cyclopentanamine Chemical compound NC1CCCC1 NISGSNTVMOOSJQ-UHFFFAOYSA-N 0.000 description 1
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- 238000009472 formulation Methods 0.000 description 1
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- 238000006062 fragmentation reaction Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
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- 108020001507 fusion proteins Proteins 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
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- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 229950006191 gluconic acid Drugs 0.000 description 1
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- 235000011187 glycerol Nutrition 0.000 description 1
- 239000011544 gradient gel Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 210000004408 hybridoma Anatomy 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 description 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 description 1
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- 238000003384 imaging method Methods 0.000 description 1
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- 239000000492 insulin antagonist Substances 0.000 description 1
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- 239000000865 liniment Substances 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
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- 239000000314 lubricant Substances 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 230000002934 lysing effect Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
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- 239000003550 marker Substances 0.000 description 1
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- PCILLCXFKWDRMK-UHFFFAOYSA-N naphthalene-1,4-diol Chemical compound C1=CC=C2C(O)=CC=C(O)C2=C1 PCILLCXFKWDRMK-UHFFFAOYSA-N 0.000 description 1
- 150000002790 naphthalenes Chemical class 0.000 description 1
- 150000002791 naphthoquinones Chemical class 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 239000012457 nonaqueous media Substances 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
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- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
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- 150000003905 phosphatidylinositols Chemical class 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 108091005981 phosphorylated proteins Proteins 0.000 description 1
- 102000020233 phosphotransferase Human genes 0.000 description 1
- DCWXELXMIBXGTH-UHFFFAOYSA-N phosphotyrosine Chemical compound OC(=O)C(N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-UHFFFAOYSA-N 0.000 description 1
- 230000003169 placental effect Effects 0.000 description 1
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- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
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- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 108060006633 protein kinase Proteins 0.000 description 1
- 230000026447 protein localization Effects 0.000 description 1
- 230000009822 protein phosphorylation Effects 0.000 description 1
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- 239000002994 raw material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- ADWNFGORSPBALY-UHFFFAOYSA-M sodium;2-[dodecyl(methyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCN(C)CC([O-])=O ADWNFGORSPBALY-UHFFFAOYSA-M 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 229910052717 sulfur Chemical group 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
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- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- 235000020357 syrup Nutrition 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003548 thiazolidines Chemical class 0.000 description 1
- 230000009092 tissue dysfunction Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000011830 transgenic mouse model Methods 0.000 description 1
- 229910001428 transition metal ion Inorganic materials 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
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- 241001430294 unidentified retrovirus Species 0.000 description 1
- WQEVDHBJGNOKKO-UHFFFAOYSA-K vanadic acid Chemical compound O[V](O)(O)=O WQEVDHBJGNOKKO-UHFFFAOYSA-K 0.000 description 1
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- 229910052725 zinc Inorganic materials 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31580693 | 1993-11-24 | ||
| JP31580693 | 1993-11-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69432511D1 DE69432511D1 (de) | 2003-05-22 |
| DE69432511T2 true DE69432511T2 (de) | 2004-04-29 |
Family
ID=18069786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69432511T Expired - Fee Related DE69432511T2 (de) | 1993-11-24 | 1994-11-24 | Protein p140 und dafür kodierende DNS |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US5506205A (enExample) |
| EP (1) | EP0659883B1 (enExample) |
| KR (1) | KR100256664B1 (enExample) |
| CN (1) | CN1057096C (enExample) |
| AT (1) | ATE237683T1 (enExample) |
| CA (1) | CA2136565C (enExample) |
| DE (1) | DE69432511T2 (enExample) |
| DK (1) | DK0659883T3 (enExample) |
| ES (1) | ES2196016T3 (enExample) |
| PT (1) | PT659883E (enExample) |
| TW (1) | TW311913B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5506205A (en) * | 1993-11-24 | 1996-04-09 | Ono Pharmaceutical Co., Ltd. | Polypeptide of protein p140 and DNAs encoding it |
| JP2004525109A (ja) | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| GB0208089D0 (en) | 2002-04-09 | 2002-05-22 | Oxford Glycosciences Uk Ltd | Protein |
| WO2008008033A1 (en) * | 2006-07-10 | 2008-01-17 | Glucox Biotech Ab | The use of naphtoquinones in the treatment and control of diabetes, insulin resistance and hyperglycemia |
| JP2010526070A (ja) * | 2007-05-01 | 2010-07-29 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム | Ｃｈｌａｍｙｄｉａ感染及び疾患の診断ならびに治療のための薬剤としてのＣｈｌａｍｙｄｉａ抗原 |
| US7892567B2 (en) * | 2007-10-01 | 2011-02-22 | Board Of Regents, The University Of Texas System | Methods and compositions for immunization against chlamydial infection and disease |
| JP4798125B2 (ja) * | 2007-12-13 | 2011-10-19 | 株式会社デンソー | 照度センサ |
| CN105085630A (zh) * | 2015-08-31 | 2015-11-25 | 苏州普罗达生物科技有限公司 | mTOR抑制多肽及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260200A (en) * | 1991-01-18 | 1993-11-09 | Joslin Diabetes Center, Inc. | Isolated DNA encoding an insulin receptor substrate |
| US5817471A (en) * | 1991-03-14 | 1998-10-06 | The United States Of America As Represented By The Department Of Health And Human Services | Trk tyrosine kinase receptor is the physiological receptor for nerve growth factor |
| US5506205A (en) * | 1993-11-24 | 1996-04-09 | Ono Pharmaceutical Co., Ltd. | Polypeptide of protein p140 and DNAs encoding it |
-
1994
- 1994-11-23 US US08/348,143 patent/US5506205A/en not_active Expired - Fee Related
- 1994-11-24 KR KR1019940031010A patent/KR100256664B1/ko not_active Expired - Fee Related
- 1994-11-24 CN CN94119935A patent/CN1057096C/zh not_active Expired - Fee Related
- 1994-11-24 ES ES94118524T patent/ES2196016T3/es not_active Expired - Lifetime
- 1994-11-24 AT AT94118524T patent/ATE237683T1/de not_active IP Right Cessation
- 1994-11-24 EP EP94118524A patent/EP0659883B1/en not_active Expired - Lifetime
- 1994-11-24 PT PT94118524T patent/PT659883E/pt unknown
- 1994-11-24 DK DK94118524T patent/DK0659883T3/da active
- 1994-11-24 CA CA002136565A patent/CA2136565C/en not_active Expired - Fee Related
- 1994-11-24 DE DE69432511T patent/DE69432511T2/de not_active Expired - Fee Related
- 1994-12-13 TW TW083111593A patent/TW311913B/zh active
-
1995
- 1995-12-13 US US08/571,785 patent/US5804411A/en not_active Expired - Fee Related
-
1998
- 1998-01-08 US US09/192,435 patent/US6303320B1/en not_active Expired - Fee Related
-
2000
- 2000-04-26 US US09/558,340 patent/US6432913B1/en not_active Expired - Fee Related
-
2002
- 2002-07-03 US US10/187,958 patent/US20030170865A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1112127A (zh) | 1995-11-22 |
| CA2136565C (en) | 1999-11-09 |
| CN1057096C (zh) | 2000-10-04 |
| US5804411A (en) | 1998-09-08 |
| US6432913B1 (en) | 2002-08-13 |
| CA2136565A1 (en) | 1995-05-25 |
| US5506205A (en) | 1996-04-09 |
| US6303320B1 (en) | 2001-10-16 |
| KR100256664B1 (ko) | 2000-05-15 |
| ES2196016T3 (es) | 2003-12-16 |
| DK0659883T3 (da) | 2003-08-04 |
| EP0659883A2 (en) | 1995-06-28 |
| EP0659883A3 (en) | 1997-06-25 |
| PT659883E (pt) | 2003-07-31 |
| KR950014135A (ko) | 1995-06-15 |
| ATE237683T1 (de) | 2003-05-15 |
| US20030170865A1 (en) | 2003-09-11 |
| TW311913B (enExample) | 1997-08-01 |
| DE69432511D1 (de) | 2003-05-22 |
| EP0659883B1 (en) | 2003-04-16 |
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