DE69418311D1 - Isoxazolidindionderivate und deren verwendung - Google Patents

Isoxazolidindionderivate und deren verwendung

Info

Publication number
DE69418311D1
DE69418311D1 DE69418311T DE69418311T DE69418311D1 DE 69418311 D1 DE69418311 D1 DE 69418311D1 DE 69418311 T DE69418311 T DE 69418311T DE 69418311 T DE69418311 T DE 69418311T DE 69418311 D1 DE69418311 D1 DE 69418311D1
Authority
DE
Germany
Prior art keywords
optionally substituted
group
represent
lower alkyl
isoxazolide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69418311T
Other languages
English (en)
Other versions
DE69418311T2 (de
Inventor
Hisashi Shinkai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tobacco Inc
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of DE69418311D1 publication Critical patent/DE69418311D1/de
Application granted granted Critical
Publication of DE69418311T2 publication Critical patent/DE69418311T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69418311T 1993-12-27 1994-12-26 Isoxazolidindionderivate und deren verwendung Expired - Fee Related DE69418311T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP35438593 1993-12-27
PCT/JP1994/002233 WO1995018125A1 (fr) 1993-12-27 1994-12-26 Derive d'isoxazolidinedione et son utilisation

Publications (2)

Publication Number Publication Date
DE69418311D1 true DE69418311D1 (de) 1999-06-10
DE69418311T2 DE69418311T2 (de) 1999-11-04

Family

ID=18437208

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69418311T Expired - Fee Related DE69418311T2 (de) 1993-12-27 1994-12-26 Isoxazolidindionderivate und deren verwendung

Country Status (12)

Country Link
US (5) US5728720A (de)
EP (1) EP0684242B1 (de)
KR (1) KR0164665B1 (de)
AT (1) ATE179709T1 (de)
CA (1) CA2157032C (de)
CY (1) CY2144B1 (de)
DE (1) DE69418311T2 (de)
DK (1) DK0684242T3 (de)
ES (1) ES2131301T3 (de)
GR (1) GR3030705T3 (de)
HK (1) HK1018164A1 (de)
WO (1) WO1995018125A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE179709T1 (de) * 1993-12-27 1999-05-15 Japan Tobacco Inc Isoxazolidindionderivate und deren verwendung
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
US6459425B1 (en) * 1997-08-25 2002-10-01 Richard A. Holub System for automatic color calibration
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
KR20000016074A (ko) * 1996-05-31 2000-03-25 가와무라 요시부미 자기면역질환 치료제
CA2257284C (en) * 1996-05-31 2005-10-04 Sankyo Company Limited Remedy for autoimmune diseases
CZ53699A3 (cs) * 1996-08-19 1999-07-14 Japan Tobacco Inc. Deriváty propionové kyseliny a jejich použití
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
HUP9902721A2 (hu) 1997-11-25 1999-12-28 The Procter & Gamble Co. Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
WO1999030739A1 (fr) * 1997-12-16 1999-06-24 Sankyo Company, Limited Remede contre la leucemie
DE69914557T2 (de) 1998-03-30 2005-01-05 Japan Tobacco Inc. Verfahren zur herstellung einer isooxazolidindion-verbindung
WO2000047209A1 (en) * 1999-01-19 2000-08-17 Tularik Inc. Methods of modulating uric acid levels
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6958355B2 (en) 2000-04-24 2005-10-25 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6768008B2 (en) * 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
DE10029077A1 (de) * 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen
AU2001294673A1 (en) * 2000-09-21 2002-04-02 Aryx Therapeutics Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, andatherosclerosis
EP1695716A2 (de) * 2000-12-26 2006-08-30 Sankyo Company, Limited Medizinische Zusammensetzungen enthaltend ein Diuretikum und einen Insulin-Sensibilisator
US20060047000A1 (en) * 2001-04-24 2006-03-02 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US20050119314A1 (en) * 2002-04-05 2005-06-02 Sankyo Company, Limited Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent
EP1613608A1 (de) * 2003-04-01 2006-01-11 Eli Lilly And Company Phospholipase inhibitoren
DE10331675A1 (de) 2003-07-14 2005-02-10 Bayer Cropscience Ag Hetarylsubstituierte Pyrazolidindion-Derivate
MA40869A (fr) 2014-10-30 2017-09-05 Sanovel Ilac Sanayi Ve Ticaret As Combinaisons pharmaceutiques de vildagliptine et d'agonistes de ppar
MA40868A (fr) 2014-10-30 2017-09-05 Sanovel Ilac Sanayi Ve Ticaret As Combinaisons pharmaceutiques de sitagliptine et d'agonistes de ppar

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051189A (ja) 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
DE3887811T2 (de) * 1987-10-15 1994-07-07 Mitsubishi Yuka Badische Faseriger Schichtstoff und Verfahren zur Herstellung desselben.
US4999366A (en) * 1988-10-31 1991-03-12 The North Carolina Central Univ. Isoxazolidine-3,5-diones, pharmaceutical compositions and method of treatment
WO1991007107A1 (en) 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
GB9017218D0 (en) 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
US5334604A (en) * 1990-08-23 1994-08-02 Pfizer Inc. Hypoglycemic hydroxyurea derivatives
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5478852C1 (en) * 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
ATE179709T1 (de) * 1993-12-27 1999-05-15 Japan Tobacco Inc Isoxazolidindionderivate und deren verwendung
US5468762A (en) * 1994-05-18 1995-11-21 American Home Products Corporation Azolidinediones as antihyperglycemic agents
US5572912A (en) * 1995-05-05 1996-11-12 Creative Designs In Woodworking And Metal Anti-crimp wrench for a garden hose with a knurled coupling

Also Published As

Publication number Publication date
EP0684242A1 (de) 1995-11-29
US6160124A (en) 2000-12-12
ATE179709T1 (de) 1999-05-15
WO1995018125A1 (fr) 1995-07-06
US6037359A (en) 2000-03-14
ES2131301T3 (es) 1999-07-16
DK0684242T3 (da) 1999-11-01
US6057343A (en) 2000-05-02
US5939445A (en) 1999-08-17
KR960701048A (ko) 1996-02-24
EP0684242B1 (de) 1999-05-06
HK1018164A1 (en) 1999-12-10
CA2157032C (en) 1999-09-28
CY2144B1 (en) 2002-06-21
US5728720A (en) 1998-03-17
KR0164665B1 (ko) 1999-01-15
CA2157032A1 (en) 1995-07-06
EP0684242A4 (de) 1995-09-28
DE69418311T2 (de) 1999-11-04
GR3030705T3 (en) 1999-11-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee