HK1018164A1 - Isoxazolidinedione derivative and use thereof - Google Patents

Isoxazolidinedione derivative and use thereof

Info

Publication number
HK1018164A1
HK1018164A1 HK98114545A HK98114545A HK1018164A1 HK 1018164 A1 HK1018164 A1 HK 1018164A1 HK 98114545 A HK98114545 A HK 98114545A HK 98114545 A HK98114545 A HK 98114545A HK 1018164 A1 HK1018164 A1 HK 1018164A1
Authority
HK
Hong Kong
Prior art keywords
optionally substituted
group
represent
lower alkyl
derivative
Prior art date
Application number
HK98114545A
Other languages
English (en)
Inventor
Hisashi Shinkai
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of HK1018164A1 publication Critical patent/HK1018164A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK98114545A 1993-12-27 1998-12-22 Isoxazolidinedione derivative and use thereof HK1018164A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP35438593 1993-12-27
PCT/JP1994/002233 WO1995018125A1 (fr) 1993-12-27 1994-12-26 Derive d'isoxazolidinedione et son utilisation

Publications (1)

Publication Number Publication Date
HK1018164A1 true HK1018164A1 (en) 1999-12-10

Family

ID=18437208

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98114545A HK1018164A1 (en) 1993-12-27 1998-12-22 Isoxazolidinedione derivative and use thereof

Country Status (12)

Country Link
US (5) US5728720A (xx)
EP (1) EP0684242B1 (xx)
KR (1) KR0164665B1 (xx)
AT (1) ATE179709T1 (xx)
CA (1) CA2157032C (xx)
CY (1) CY2144B1 (xx)
DE (1) DE69418311T2 (xx)
DK (1) DK0684242T3 (xx)
ES (1) ES2131301T3 (xx)
GR (1) GR3030705T3 (xx)
HK (1) HK1018164A1 (xx)
WO (1) WO1995018125A1 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0684242B1 (en) * 1993-12-27 1999-05-06 Japan Tobacco Inc. Isoxazolidinedione derivative and use thereof
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
US6459425B1 (en) * 1997-08-25 2002-10-01 Richard A. Holub System for automatic color calibration
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
NZ333065A (en) * 1996-05-31 2000-05-26 Sankyo Co Treatment or prevention of autoimmune diseases using an insulin resistance improving thiazolidinedione derivative
CA2257284C (en) * 1996-05-31 2005-10-04 Sankyo Company Limited Remedy for autoimmune diseases
KR20000068151A (ko) 1996-08-19 2000-11-25 미즈노 마사루 프로피온산 유도체 및 그의 용도
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
HUP9902721A2 (hu) * 1997-11-25 1999-12-28 The Procter & Gamble Co. Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
WO1999030739A1 (fr) * 1997-12-16 1999-06-24 Sankyo Company, Limited Remede contre la leucemie
RU2180663C2 (ru) 1998-03-30 2002-03-20 Джапан Тобакко Инк. Способ получения изоксазолидиндионового соединения, способ получения оксазолилэтанольного соединения (варианты), способ получения аспартатного соединения, способ получения оксазолилацетатного соединения, способ получения метансульфонатного соединения, способ получения бензилиденового соединения
WO2000047209A1 (en) * 1999-01-19 2000-08-17 Tularik Inc. Methods of modulating uric acid levels
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6784199B2 (en) 2000-09-21 2004-08-31 Aryx Therapeutics Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6958355B2 (en) 2000-04-24 2005-10-25 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
DE10029077A1 (de) * 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen
EP1354602B1 (en) * 2000-12-26 2006-10-04 Sankyo Company, Limited Medicinal compositions containing diuretic and insulin resistance-improving agent
US20060047000A1 (en) * 2001-04-24 2006-03-02 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US20050119314A1 (en) * 2002-04-05 2005-06-02 Sankyo Company, Limited Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent
EP1613608A1 (en) 2003-04-01 2006-01-11 Eli Lilly And Company Phospholipase inhibitors
DE10331675A1 (de) 2003-07-14 2005-02-10 Bayer Cropscience Ag Hetarylsubstituierte Pyrazolidindion-Derivate
MA40868A (fr) 2014-10-30 2017-09-05 Sanovel Ilac Sanayi Ve Ticaret As Combinaisons pharmaceutiques de sitagliptine et d'agonistes de ppar
MA40869A (fr) 2014-10-30 2017-09-05 Sanovel Ilac Sanayi Ve Ticaret As Combinaisons pharmaceutiques de vildagliptine et d'agonistes de ppar

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
EP0312090B1 (en) * 1987-10-15 1994-02-16 Mitsubishi Yuka Badische Co., Ltd. Fibrous laminate and process of producing the same
US4999366A (en) * 1988-10-31 1991-03-12 The North Carolina Central Univ. Isoxazolidine-3,5-diones, pharmaceutical compositions and method of treatment
WO1991007107A1 (en) 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
GB9017218D0 (en) 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
KR930701420A (ko) * 1990-08-23 1993-06-11 알렌 제이. 스피겔 혈당저하제로서의 하이드록시우레아 유도체
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5457109A (en) * 1993-09-15 1995-10-10 Warner-Lambert Company Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
EP0684242B1 (en) * 1993-12-27 1999-05-06 Japan Tobacco Inc. Isoxazolidinedione derivative and use thereof
US5468762A (en) * 1994-05-18 1995-11-21 American Home Products Corporation Azolidinediones as antihyperglycemic agents
US5572912A (en) * 1995-05-05 1996-11-12 Creative Designs In Woodworking And Metal Anti-crimp wrench for a garden hose with a knurled coupling

Also Published As

Publication number Publication date
US6037359A (en) 2000-03-14
US5939445A (en) 1999-08-17
ES2131301T3 (es) 1999-07-16
EP0684242A4 (en) 1995-09-28
CY2144B1 (en) 2002-06-21
EP0684242B1 (en) 1999-05-06
US6057343A (en) 2000-05-02
EP0684242A1 (en) 1995-11-29
KR960701048A (ko) 1996-02-24
CA2157032C (en) 1999-09-28
US5728720A (en) 1998-03-17
KR0164665B1 (ko) 1999-01-15
CA2157032A1 (en) 1995-07-06
DE69418311T2 (de) 1999-11-04
US6160124A (en) 2000-12-12
WO1995018125A1 (fr) 1995-07-06
GR3030705T3 (en) 1999-11-30
DE69418311D1 (de) 1999-06-10
ATE179709T1 (de) 1999-05-15
DK0684242T3 (da) 1999-11-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20031223

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)