DE69408135T2 - Ospc-antigen-impfstoffe immunogene zusammensetzung zur vorbeugung und behandlung von lyme-krankheit und rekombinante verfahren zur herstellung von derartige antigene - Google Patents
Ospc-antigen-impfstoffe immunogene zusammensetzung zur vorbeugung und behandlung von lyme-krankheit und rekombinante verfahren zur herstellung von derartige antigeneInfo
- Publication number
- DE69408135T2 DE69408135T2 DE69408135T DE69408135T DE69408135T2 DE 69408135 T2 DE69408135 T2 DE 69408135T2 DE 69408135 T DE69408135 T DE 69408135T DE 69408135 T DE69408135 T DE 69408135T DE 69408135 T2 DE69408135 T2 DE 69408135T2
- Authority
- DE
- Germany
- Prior art keywords
- antigens
- ospc
- vaccinals
- antigue
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 208000016604 Lyme disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- NMJCSTNQFYPVOR-VHONOUADSA-N 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCC\C=C/CCCCCCCC NMJCSTNQFYPVOR-VHONOUADSA-N 0.000 title 1
- 101001066818 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) Protostadienol synthase helA Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 238000010188 recombinant method Methods 0.000 title 1
- 108700023315 OspC Proteins 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 241000589968 Borrelia Species 0.000 abstract 1
- 241000589969 Borreliella burgdorferi Species 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000000405 serological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5386393A | 1993-04-29 | 1993-04-29 | |
| PCT/EP1994/001365 WO1994025596A2 (en) | 1993-04-29 | 1994-04-29 | IMMUNOGENIC FORMULATION OF OspC ANTIGEN VACCINES FOR THE PREVENTION AND TREATMENT OF LYME DISEASE AND RECOMBINANT METHODS FOR THE PREPARATION OF SUCH ANTIGENS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69408135D1 DE69408135D1 (de) | 1998-02-26 |
| DE69408135T2 true DE69408135T2 (de) | 1998-06-10 |
Family
ID=21987063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69408135T Expired - Fee Related DE69408135T2 (de) | 1993-04-29 | 1994-04-29 | Ospc-antigen-impfstoffe immunogene zusammensetzung zur vorbeugung und behandlung von lyme-krankheit und rekombinante verfahren zur herstellung von derartige antigene |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0701612B1 (de) |
| JP (1) | JPH08509371A (de) |
| AT (1) | ATE162550T1 (de) |
| AU (1) | AU683260B2 (de) |
| CA (1) | CA2161534A1 (de) |
| CZ (1) | CZ289212B6 (de) |
| DE (1) | DE69408135T2 (de) |
| DK (1) | DK0701612T3 (de) |
| ES (1) | ES2114687T3 (de) |
| FI (1) | FI955150A (de) |
| HR (1) | HRP940279B1 (de) |
| HU (1) | HU217024B (de) |
| NO (1) | NO954318L (de) |
| PL (1) | PL178775B1 (de) |
| SK (1) | SK279968B6 (de) |
| WO (1) | WO1994025596A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5915049A (en) * | 1992-02-25 | 1999-06-22 | Pfu Limited | Binarization system for an image scanner |
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| DE69718903T2 (de) * | 1996-05-02 | 2003-12-04 | Dakocytomation Denmark As Glos | Verwendung von aus osp-c abgeleiteten peptidefragmenten für diagnostische methoden |
| US6716574B2 (en) | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
| US5846946A (en) * | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| AT405940B (de) * | 1996-06-21 | 1999-12-27 | Immuno Ag | Verfahren zur gewinnung und reinigung von rekombinantem, nicht-lipidiertem osp-protein |
| DE19629543C2 (de) * | 1996-07-22 | 1999-02-11 | Immuno Ag | Immunassay zum Nachweis von anti-B. burgdorferi Antikörpern und Verfahren zur Serodiagnose bei Lyme Borreliose, diagnostische Mittel und Testkits zur Durchführung der Verfahren |
| DE19740735A1 (de) | 1997-09-16 | 1999-03-18 | Max Planck Gesellschaft | Arzneimittel zur Therapie einer manifesten Lyme-Borreliose |
| ATE386805T1 (de) | 1998-07-31 | 2008-03-15 | Gundersen Lutheran Medical Fou | Verwendungen eines borreliaziden epitops des aussermembranproteins c von borrelia burgdorferi (ospc) als impstoff |
| WO2000078966A1 (en) * | 1999-06-18 | 2000-12-28 | Research Foundation Of State University Of New York | Groups of borrelia burgdorferi and borrelia afzelii that cause lyme disease in humans |
| AU2001285049A1 (en) | 2000-08-18 | 2002-03-04 | Brookhaven Sciences Associates, Llc | Altered ospa of borrelia burgdorferi |
| GB2414667A (en) | 2004-06-03 | 2005-12-07 | Isis Innovation | Vaccine compositions of N. meningitidis PorA and FetA antigens |
| EP1957520A4 (de) * | 2005-11-29 | 2009-05-27 | Univ Virginia Commonwealth | Polyvalentes chimärisches ospc-vaccinogen und diagnostisches antigen |
| EP2077856B1 (de) * | 2006-11-03 | 2015-08-12 | Intervet International BV | Lyme-impfstoff für hunde |
| CZ301244B6 (cs) * | 2007-11-14 | 2009-12-16 | Bioveta, A.S. | Univerzální vakcína k lécbe a prevenci Lymeské borreliózy pro humánní a veterinární použití a zpusob její výroby |
| CZ301548B6 (cs) * | 2008-08-20 | 2010-04-14 | Bittner@Libor | Univerzální preparát ke zvýšení obranyschopnosti, prevenci, profylaxi a lécbe Lymeské boreliózy pro humánní a veterinární použití, zpusob jeho výroby a použití |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221363B1 (en) * | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
-
1994
- 1994-04-29 AU AU67229/94A patent/AU683260B2/en not_active Ceased
- 1994-04-29 HU HU9502002A patent/HU217024B/hu not_active IP Right Cessation
- 1994-04-29 DE DE69408135T patent/DE69408135T2/de not_active Expired - Fee Related
- 1994-04-29 DK DK94915562T patent/DK0701612T3/da active
- 1994-04-29 ES ES94915562T patent/ES2114687T3/es not_active Expired - Lifetime
- 1994-04-29 CA CA002161534A patent/CA2161534A1/en not_active Abandoned
- 1994-04-29 SK SK1341-95A patent/SK279968B6/sk unknown
- 1994-04-29 WO PCT/EP1994/001365 patent/WO1994025596A2/en active IP Right Grant
- 1994-04-29 JP JP6523899A patent/JPH08509371A/ja not_active Ceased
- 1994-04-29 CZ CZ19952839A patent/CZ289212B6/cs not_active IP Right Cessation
- 1994-04-29 EP EP94915562A patent/EP0701612B1/de not_active Expired - Lifetime
- 1994-04-29 AT AT94915562T patent/ATE162550T1/de not_active IP Right Cessation
- 1994-04-29 HR HR940279A patent/HRP940279B1/xx not_active IP Right Cessation
- 1994-04-29 PL PL94311301A patent/PL178775B1/pl not_active IP Right Cessation
-
1995
- 1995-10-27 FI FI955150A patent/FI955150A/fi not_active IP Right Cessation
- 1995-10-27 NO NO954318A patent/NO954318L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6722994A (en) | 1994-11-21 |
| JPH08509371A (ja) | 1996-10-08 |
| FI955150A0 (fi) | 1995-10-27 |
| WO1994025596A2 (en) | 1994-11-10 |
| NO954318L (no) | 1995-12-29 |
| PL178775B1 (pl) | 2000-06-30 |
| HRP940279A2 (en) | 1997-10-31 |
| SK279968B6 (sk) | 1999-06-11 |
| CZ289212B6 (cs) | 2001-12-12 |
| CA2161534A1 (en) | 1994-11-10 |
| EP0701612B1 (de) | 1998-01-21 |
| PL311301A1 (en) | 1996-02-05 |
| ES2114687T3 (es) | 1998-06-01 |
| DK0701612T3 (da) | 1998-09-21 |
| NO954318D0 (no) | 1995-10-27 |
| AU683260B2 (en) | 1997-11-06 |
| HUT72923A (en) | 1996-06-28 |
| HU9502002D0 (en) | 1995-08-28 |
| EP0701612A1 (de) | 1996-03-20 |
| WO1994025596A3 (en) | 1994-12-22 |
| SK134195A3 (en) | 1996-05-08 |
| FI955150A (fi) | 1995-12-28 |
| ATE162550T1 (de) | 1998-02-15 |
| DE69408135D1 (de) | 1998-02-26 |
| CZ283995A3 (en) | 1996-03-13 |
| HRP940279B1 (en) | 2000-12-31 |
| HU217024B (hu) | 1999-11-29 |
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| DE69408135D1 (de) | Ospc-antigen-impfstoffe immunogene zusammensetzung zur vorbeugung und behandlung von lyme-krankheit und rekombinante verfahren zur herstellung von derartige antigene | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |