ES2114687T3 - Formulacion inmunogena a base de antigenos ospc, destinada para la prevencion y para el tratamiento de la enfermedad de lyme y procedimientos de recombinacion para la preparacion de estos antigenos. - Google Patents
Formulacion inmunogena a base de antigenos ospc, destinada para la prevencion y para el tratamiento de la enfermedad de lyme y procedimientos de recombinacion para la preparacion de estos antigenos.Info
- Publication number
- ES2114687T3 ES2114687T3 ES94915562T ES94915562T ES2114687T3 ES 2114687 T3 ES2114687 T3 ES 2114687T3 ES 94915562 T ES94915562 T ES 94915562T ES 94915562 T ES94915562 T ES 94915562T ES 2114687 T3 ES2114687 T3 ES 2114687T3
- Authority
- ES
- Spain
- Prior art keywords
- antigens
- ospc
- prevention
- preparation
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 101001066818 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) Protostadienol synthase helA Proteins 0.000 title abstract 3
- NMJCSTNQFYPVOR-VHONOUADSA-N 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCC\C=C/CCCCCCCC NMJCSTNQFYPVOR-VHONOUADSA-N 0.000 title abstract 2
- 208000016604 Lyme disease Diseases 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 238000005215 recombination Methods 0.000 title 1
- 230000006798 recombination Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 abstract 2
- 241000589968 Borrelia Species 0.000 abstract 1
- 241000589969 Borreliella burgdorferi Species 0.000 abstract 1
- 230000000405 serological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
UN ENFOQUE EN LA FORMULACION DE VACUNA BORRELIA, TOMANDO EN CUENTA LA INFORMACION SEROLOGICA, GENOTIPICA Y EPIDEMIOLOGICA POR LA QUE LAS PROTEINAS OSPC DE DIFERENTES RAMIFICACIONES DE B. BURGDORFERI SON AGRUPADOS ENTRE SI. LOS ANTIGENOS OSPC SON ELEGIDOS PARA CONSTITUIR UNA MUESTRA REPRESENTATIVA DE TALES GRUPOS, DE MANERA QUE LA VACUNA RESULTANTE PROPORCIONA LA MAYOR PROTECCION CRUZADA CON EL MENOR NUMERO DE ANTIGENOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5386393A | 1993-04-29 | 1993-04-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2114687T3 true ES2114687T3 (es) | 1998-06-01 |
Family
ID=21987063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94915562T Expired - Lifetime ES2114687T3 (es) | 1993-04-29 | 1994-04-29 | Formulacion inmunogena a base de antigenos ospc, destinada para la prevencion y para el tratamiento de la enfermedad de lyme y procedimientos de recombinacion para la preparacion de estos antigenos. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0701612B1 (es) |
JP (1) | JPH08509371A (es) |
AT (1) | ATE162550T1 (es) |
AU (1) | AU683260B2 (es) |
CA (1) | CA2161534A1 (es) |
CZ (1) | CZ289212B6 (es) |
DE (1) | DE69408135T2 (es) |
DK (1) | DK0701612T3 (es) |
ES (1) | ES2114687T3 (es) |
FI (1) | FI955150A (es) |
HR (1) | HRP940279B1 (es) |
HU (1) | HU217024B (es) |
NO (1) | NO954318L (es) |
PL (1) | PL178775B1 (es) |
SK (1) | SK279968B6 (es) |
WO (1) | WO1994025596A2 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5915049A (en) * | 1992-02-25 | 1999-06-22 | Pfu Limited | Binarization system for an image scanner |
US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
ATE232212T1 (de) * | 1996-05-02 | 2003-02-15 | Dako As | Verwendung von aus osp-c abgeleiteten peptidefragmenten für diagnostische methoden |
US6716574B2 (en) | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
US5846946A (en) * | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
AT405940B (de) * | 1996-06-21 | 1999-12-27 | Immuno Ag | Verfahren zur gewinnung und reinigung von rekombinantem, nicht-lipidiertem osp-protein |
DE19629543C2 (de) * | 1996-07-22 | 1999-02-11 | Immuno Ag | Immunassay zum Nachweis von anti-B. burgdorferi Antikörpern und Verfahren zur Serodiagnose bei Lyme Borreliose, diagnostische Mittel und Testkits zur Durchführung der Verfahren |
DE19740735A1 (de) * | 1997-09-16 | 1999-03-18 | Max Planck Gesellschaft | Arzneimittel zur Therapie einer manifesten Lyme-Borreliose |
AU5328299A (en) * | 1998-07-31 | 2000-02-21 | Gundersen Lutheran Medical Foundation, Inc. | Uses of the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein c (ospc) as vaccine |
DE60030859T2 (de) | 1999-06-18 | 2007-06-14 | The Research Foundation Of State University Of New York | Gruppen von borrelia burgdorferi, die lyme krankheit verursachen |
DE60131982T2 (de) | 2000-08-18 | 2008-12-11 | Brookhaven Science Associates Llc | Veränderte borrelia burgdorferi ospa |
GB2414667A (en) * | 2004-06-03 | 2005-12-07 | Isis Innovation | Vaccine compositions of N. meningitidis PorA and FetA antigens |
JP5390189B2 (ja) * | 2005-11-29 | 2014-01-15 | ヴァージニア コモンウェルス ユニバーシティ | 多価キメラospcワクシノーゲンおよび診断用抗原 |
RU2460538C2 (ru) * | 2006-11-03 | 2012-09-10 | Шеринг-Плоу Лтд. | Вакцина против лаймской болезни собак |
CZ301244B6 (cs) * | 2007-11-14 | 2009-12-16 | Bioveta, A.S. | Univerzální vakcína k lécbe a prevenci Lymeské borreliózy pro humánní a veterinární použití a zpusob její výroby |
CZ301548B6 (cs) * | 2008-08-20 | 2010-04-14 | Bittner@Libor | Univerzální preparát ke zvýšení obranyschopnosti, prevenci, profylaxi a lécbe Lymeské boreliózy pro humánní a veterinární použití, zpusob jeho výroby a použití |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6221363B1 (en) * | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
-
1994
- 1994-04-29 HR HR940279A patent/HRP940279B1/xx not_active IP Right Cessation
- 1994-04-29 EP EP94915562A patent/EP0701612B1/en not_active Expired - Lifetime
- 1994-04-29 PL PL94311301A patent/PL178775B1/pl not_active IP Right Cessation
- 1994-04-29 WO PCT/EP1994/001365 patent/WO1994025596A2/en active IP Right Grant
- 1994-04-29 CA CA002161534A patent/CA2161534A1/en not_active Abandoned
- 1994-04-29 CZ CZ19952839A patent/CZ289212B6/cs not_active IP Right Cessation
- 1994-04-29 ES ES94915562T patent/ES2114687T3/es not_active Expired - Lifetime
- 1994-04-29 DK DK94915562T patent/DK0701612T3/da active
- 1994-04-29 DE DE69408135T patent/DE69408135T2/de not_active Expired - Fee Related
- 1994-04-29 JP JP6523899A patent/JPH08509371A/ja not_active Ceased
- 1994-04-29 AU AU67229/94A patent/AU683260B2/en not_active Ceased
- 1994-04-29 SK SK1341-95A patent/SK279968B6/sk unknown
- 1994-04-29 AT AT94915562T patent/ATE162550T1/de not_active IP Right Cessation
- 1994-04-29 HU HU9502002A patent/HU217024B/hu not_active IP Right Cessation
-
1995
- 1995-10-27 FI FI955150A patent/FI955150A/fi not_active IP Right Cessation
- 1995-10-27 NO NO954318A patent/NO954318L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HRP940279A2 (en) | 1997-10-31 |
ATE162550T1 (de) | 1998-02-15 |
NO954318D0 (no) | 1995-10-27 |
FI955150A0 (fi) | 1995-10-27 |
WO1994025596A3 (en) | 1994-12-22 |
AU6722994A (en) | 1994-11-21 |
AU683260B2 (en) | 1997-11-06 |
JPH08509371A (ja) | 1996-10-08 |
NO954318L (no) | 1995-12-29 |
CZ283995A3 (en) | 1996-03-13 |
HU9502002D0 (en) | 1995-08-28 |
SK134195A3 (en) | 1996-05-08 |
EP0701612A1 (en) | 1996-03-20 |
FI955150A (fi) | 1995-12-28 |
CA2161534A1 (en) | 1994-11-10 |
HU217024B (hu) | 1999-11-29 |
CZ289212B6 (cs) | 2001-12-12 |
PL311301A1 (en) | 1996-02-05 |
DK0701612T3 (da) | 1998-09-21 |
PL178775B1 (pl) | 2000-06-30 |
HRP940279B1 (en) | 2000-12-31 |
EP0701612B1 (en) | 1998-01-21 |
DE69408135D1 (de) | 1998-02-26 |
WO1994025596A2 (en) | 1994-11-10 |
HUT72923A (en) | 1996-06-28 |
DE69408135T2 (de) | 1998-06-10 |
SK279968B6 (sk) | 1999-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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