DE69331931D1 - Synthetische eukaryotische Promotoren welche zwei induzierbare Elemente enthalten - Google Patents

Synthetische eukaryotische Promotoren welche zwei induzierbare Elemente enthalten

Info

Publication number
DE69331931D1
DE69331931D1 DE69331931T DE69331931T DE69331931D1 DE 69331931 D1 DE69331931 D1 DE 69331931D1 DE 69331931 T DE69331931 T DE 69331931T DE 69331931 T DE69331931 T DE 69331931T DE 69331931 D1 DE69331931 D1 DE 69331931D1
Authority
DE
Germany
Prior art keywords
elements
pct
promoters
inducible
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331931T
Other languages
English (en)
Other versions
DE69331931T2 (de
Inventor
Jorge Filmus
Michel Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Aventis Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur Ltd filed Critical Aventis Pasteur Ltd
Application granted granted Critical
Publication of DE69331931D1 publication Critical patent/DE69331931D1/de
Publication of DE69331931T2 publication Critical patent/DE69331931T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Soil Working Implements (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Multicomponent Fibers (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69331931T 1992-03-30 1993-03-30 Synthetische eukaryotische Promotoren welche zwei induzierbare Elemente enthalten Expired - Lifetime DE69331931T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929206874A GB9206874D0 (en) 1992-03-30 1992-03-30 Generation of improved inducible mammalian expression vectors
PCT/CA1993/000130 WO1993020218A1 (en) 1992-03-30 1993-03-30 Synthetic eukaryotic promoters containing two inducible elements

Publications (2)

Publication Number Publication Date
DE69331931D1 true DE69331931D1 (de) 2002-06-20
DE69331931T2 DE69331931T2 (de) 2002-09-12

Family

ID=10713085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331931T Expired - Lifetime DE69331931T2 (de) 1992-03-30 1993-03-30 Synthetische eukaryotische Promotoren welche zwei induzierbare Elemente enthalten

Country Status (17)

Country Link
US (1) US5559027A (de)
EP (1) EP0633941B1 (de)
JP (1) JP2701983B2 (de)
KR (1) KR100208311B1 (de)
AT (1) ATE217649T1 (de)
AU (1) AU667532B2 (de)
BR (1) BR9306167A (de)
CA (1) CA2128602C (de)
DE (1) DE69331931T2 (de)
DK (1) DK0633941T3 (de)
ES (1) ES2176202T3 (de)
FI (1) FI113548B (de)
GB (1) GB9206874D0 (de)
NO (1) NO316451B1 (de)
PT (1) PT633941E (de)
RU (1) RU2128225C1 (de)
WO (1) WO1993020218A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071695A (en) * 1992-02-21 2000-06-06 Creative Biomolecules, Inc. Methods and products for identification of modulators of osteogenic protein-1 gene expression
US5512483A (en) * 1993-05-21 1996-04-30 Mcgill University Expression vectors responsive to steroid hormones
JPH07163368A (ja) * 1993-12-15 1995-06-27 Hayashibara Biochem Lab Inc 組換えdnaとその組換えdnaを含む形質転換体
AU703445B2 (en) * 1994-06-07 1999-03-25 Stryker Corporation Methods and compositions for modulating morphogenic protein expression
CA2296771A1 (en) 1997-07-14 1999-01-21 Valentis, Inc. Method for the identification of synthetic cell- or tissue-specific transcriptional regulatory regions
AU748334B2 (en) 1997-10-16 2002-05-30 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with NF-AT3 function
FR2772786A1 (fr) * 1997-12-18 1999-06-25 Inst Nat Sante Rech Med Sequences nucleotidiques chevauchantes, et leur utilisation dans le cadre de la detection de xenohormones ainsi que dans des compositions pharmaceutiques
JP2002537311A (ja) * 1999-02-19 2002-11-05 オクタジーン・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ホルモン−ホルモン受容体の複合体および核酸構築物、並びに遺伝子治療におけるそれらの使用
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
US7341847B2 (en) * 2003-04-02 2008-03-11 Agency For Science, Technology And Research Promoter construct for gene expression in neuronal cells
EP1681988B1 (de) 2003-11-12 2015-04-08 The Children's Hospital Medical Center Verfahren zur diagnose und behandlung von lungenerkrankungen
KR100647490B1 (ko) * 2004-10-04 2006-11-23 사회복지법인 삼성생명공익재단 저산소 조건 및 다른 스트레스에 특이적으로 반응할 수있는 키메라 인핸서 요소를 포함하는 벡터, 상기 벡터를포함하는 약제학적 조성물 및 상기 조성물을 이용하는 방법
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
JP5495360B2 (ja) * 2006-09-04 2014-05-21 Bio−energy株式会社 ポリエステルポリオール
RU2370280C2 (ru) * 2007-10-08 2009-10-20 Институт физико-химической биологии им. А.Н.Белозерского СПОСОБ СУПЕРПРОДУКЦИИ В РАСТЕНИИ АНТИТЕЛ ПРОТИВ ОНКОГЕНА HER2/neu
US8551733B2 (en) 2009-02-09 2013-10-08 Morphosys Ag Production of oligoclonal mixtures of immunoglobulins in single cells
EP2571991A1 (de) 2010-05-20 2013-03-27 Evolva SA Verfahren zur herstellung von isoprenoidverbindungen in hefe
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
AU2018376259A1 (en) 2017-11-30 2020-06-11 Friedrich Miescher Institute For Biomedical Research SynPIII, a promoter for the specific expression of genes in retinal pigment epithelium

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983001783A1 (en) * 1981-11-23 1983-05-26 University Patents Inc Control of dna sequence transcription
EP0511285A4 (en) * 1990-01-18 1993-05-26 Us Commerce Vector with multiple target response elements affecting gene expression
CA2075182C (en) * 1990-02-09 2003-03-25 David J. Mangelsdorf Retinoid receptor compositions and methods

Also Published As

Publication number Publication date
ATE217649T1 (de) 2002-06-15
KR100208311B1 (ko) 1999-07-15
RU94042389A (ru) 1997-03-10
ES2176202T3 (es) 2002-12-01
JP2701983B2 (ja) 1998-01-21
FI113548B (fi) 2004-05-14
CA2128602A1 (en) 1993-10-14
CA2128602C (en) 2008-01-22
AU3883393A (en) 1993-11-08
KR950700420A (ko) 1995-01-16
DE69331931T2 (de) 2002-09-12
WO1993020218A1 (en) 1993-10-14
FI944451A0 (fi) 1994-09-26
DK0633941T3 (da) 2002-06-17
PT633941E (pt) 2002-10-31
EP0633941A1 (de) 1995-01-18
AU667532B2 (en) 1996-03-28
EP0633941B1 (de) 2002-05-15
US5559027A (en) 1996-09-24
NO943610L (no) 1994-11-30
BR9306167A (pt) 1998-01-13
NO316451B1 (no) 2004-01-26
RU2128225C1 (ru) 1999-03-27
JPH07501456A (ja) 1995-02-16
GB9206874D0 (en) 1992-05-13
FI944451A (fi) 1994-09-26
NO943610D0 (no) 1994-09-29

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