DE69331237T2 - Antiatherosclerotische mittel - Google Patents

Antiatherosclerotische mittel

Info

Publication number
DE69331237T2
DE69331237T2 DE69331237T DE69331237T DE69331237T2 DE 69331237 T2 DE69331237 T2 DE 69331237T2 DE 69331237 T DE69331237 T DE 69331237T DE 69331237 T DE69331237 T DE 69331237T DE 69331237 T2 DE69331237 T2 DE 69331237T2
Authority
DE
Germany
Prior art keywords
ester
dihydroequilin
alpha
sulfate
absence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331237T
Other languages
English (en)
Other versions
DE69331237D1 (de
Inventor
Steven Jay Adelman
Kurt Edric Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/157,661 external-priority patent/US5482935A/en
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of DE69331237D1 publication Critical patent/DE69331237D1/de
Application granted granted Critical
Publication of DE69331237T2 publication Critical patent/DE69331237T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
DE69331237T 1993-01-05 1993-12-22 Antiatherosclerotische mittel Expired - Fee Related DE69331237T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77793A 1993-01-05 1993-01-05
US08/157,661 US5482935A (en) 1993-01-05 1993-12-01 Anti-atherosclerotic use of 17 alpha-dihydroequilin
PCT/US1993/012559 WO1994015612A1 (en) 1993-01-05 1993-12-22 Anti-atherosclerotic agents

Publications (2)

Publication Number Publication Date
DE69331237D1 DE69331237D1 (de) 2002-01-10
DE69331237T2 true DE69331237T2 (de) 2002-06-13

Family

ID=26668138

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331237T Expired - Fee Related DE69331237T2 (de) 1993-01-05 1993-12-22 Antiatherosclerotische mittel

Country Status (17)

Country Link
EP (1) EP0678027B1 (de)
JP (1) JP3344585B2 (de)
CN (1) CN1071573C (de)
AT (1) ATE209495T1 (de)
AU (1) AU6015794A (de)
CA (1) CA2152187A1 (de)
CY (1) CY2361B1 (de)
DE (1) DE69331237T2 (de)
DK (1) DK0678027T3 (de)
ES (1) ES2165382T3 (de)
HK (1) HK1011282A1 (de)
IL (1) IL108155A (de)
MX (1) MX9400254A (de)
PH (1) PH30474A (de)
PT (1) PT678027E (de)
SG (1) SG52359A1 (de)
WO (1) WO1994015612A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855703B1 (en) * 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507889A (en) * 1968-06-11 1970-04-21 American Home Prod Process for the preparation of 17alpha-dihydroequilenin and related compounds
US3608075A (en) * 1969-07-28 1971-09-21 American Home Prod Compositions and methods of treating the menopausal syndrome
US4154820A (en) * 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
US4379780A (en) * 1980-09-29 1983-04-12 American Home Products Corporation 17 α-Dihydroequilin hapten and assay method

Also Published As

Publication number Publication date
DE69331237D1 (de) 2002-01-10
HK1011282A1 (en) 1999-07-09
MX9400254A (es) 1994-08-31
ES2165382T3 (es) 2002-03-16
CY2361B1 (en) 2004-06-04
IL108155A (en) 1999-08-17
EP0678027B1 (de) 2001-11-28
EP0678027A1 (de) 1995-10-25
ATE209495T1 (de) 2001-12-15
PH30474A (en) 1997-05-28
DK0678027T3 (da) 2002-03-18
CN1071573C (zh) 2001-09-26
WO1994015612A1 (en) 1994-07-21
AU6015794A (en) 1994-08-15
SG52359A1 (en) 1998-09-28
JP3344585B2 (ja) 2002-11-11
IL108155A0 (en) 1994-04-12
CN1096443A (zh) 1994-12-21
PT678027E (pt) 2002-04-29
CA2152187A1 (en) 1994-07-21
JPH08505392A (ja) 1996-06-11

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: WYETH (N.D.GES.D. STAATES DELAWARE), MADISON, N.J.

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee