DE69321538T2 - Wässrige Dispersionen von Zein und Beschichtungen mit gesteuerter Freisetzung - Google Patents

Wässrige Dispersionen von Zein und Beschichtungen mit gesteuerter Freisetzung

Info

Publication number
DE69321538T2
DE69321538T2 DE69321538T DE69321538T DE69321538T2 DE 69321538 T2 DE69321538 T2 DE 69321538T2 DE 69321538 T DE69321538 T DE 69321538T DE 69321538 T DE69321538 T DE 69321538T DE 69321538 T2 DE69321538 T2 DE 69321538T2
Authority
DE
Germany
Prior art keywords
zein
controlled release
aqueous dispersions
release coatings
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69321538T
Other languages
English (en)
Other versions
DE69321538D1 (de
Inventor
Benjamin Oshlack
Mark Chasin
James Mcginity
Roland Bodmeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of DE69321538D1 publication Critical patent/DE69321538D1/de
Application granted granted Critical
Publication of DE69321538T2 publication Critical patent/DE69321538T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/07—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from polymer solutions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/14—Vegetable proteins
    • A23J3/18—Vegetable proteins from wheat
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P20/00—Coating of foodstuffs; Coatings therefor; Making laminated, multi-layered, stuffed or hollow foodstuffs
    • A23P20/10—Coating with edible coatings, e.g. with oils or fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2873—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2389/00—Characterised by the use of proteins; Derivatives thereof
DE69321538T 1992-08-13 1993-08-12 Wässrige Dispersionen von Zein und Beschichtungen mit gesteuerter Freisetzung Expired - Fee Related DE69321538T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/930,107 US5324351A (en) 1992-08-13 1992-08-13 Aqueous dispersions of zein and preparation thereof

Publications (2)

Publication Number Publication Date
DE69321538D1 DE69321538D1 (de) 1998-11-19
DE69321538T2 true DE69321538T2 (de) 1999-05-06

Family

ID=25458930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69321538T Expired - Fee Related DE69321538T2 (de) 1992-08-13 1993-08-12 Wässrige Dispersionen von Zein und Beschichtungen mit gesteuerter Freisetzung

Country Status (14)

Country Link
US (2) US5324351A (de)
EP (1) EP0585688B1 (de)
JP (1) JPH06172398A (de)
KR (1) KR940005265A (de)
CN (1) CN1086144A (de)
AT (1) ATE172224T1 (de)
AU (1) AU4462193A (de)
CA (1) CA2103635A1 (de)
DE (1) DE69321538T2 (de)
IL (1) IL106647A0 (de)
MX (1) MX9304900A (de)
NO (1) NO932867L (de)
PL (1) PL300087A1 (de)
ZA (1) ZA935869B (de)

Families Citing this family (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5709827A (en) 1992-08-11 1998-01-20 E. Khashoggi Industries Methods for manufacturing articles having a starch-bound cellular matrix
US5662731A (en) 1992-08-11 1997-09-02 E. Khashoggi Industries Compositions for manufacturing fiber-reinforced, starch-bound articles having a foamed cellular matrix
US5679145A (en) 1992-08-11 1997-10-21 E. Khashoggi Industries Starch-based compositions having uniformly dispersed fibers used to manufacture high strength articles having a fiber-reinforced, starch-bound cellular matrix
US5810961A (en) 1993-11-19 1998-09-22 E. Khashoggi Industries, Llc Methods for manufacturing molded sheets having a high starch content
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
US5716675A (en) 1992-11-25 1998-02-10 E. Khashoggi Industries Methods for treating the surface of starch-based articles with glycerin
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
US5747416A (en) * 1993-07-08 1998-05-05 Mcardle; Blaise Herbicidal and insecticidal protein-polysaccharide delivery compositions and methods for controlling plant and insect populations
US5645880A (en) * 1993-07-08 1997-07-08 Mcardle; Blaise Protein-polysaccharide complex composition and method of use
AU7219094A (en) * 1993-07-14 1995-02-13 Opta Food Ingredients, Inc. Shellac dispersions and coatings, and method of making
US5662933A (en) * 1993-09-09 1997-09-02 Edward Mendell Co., Inc. Controlled release formulation (albuterol)
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US6726930B1 (en) * 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US6083586A (en) 1993-11-19 2000-07-04 E. Khashoggi Industries, Llc Sheets having a starch-based binding matrix
US5736209A (en) 1993-11-19 1998-04-07 E. Kashoggi, Industries, Llc Compositions having a high ungelatinized starch content and sheets molded therefrom
US5500227A (en) * 1993-11-23 1996-03-19 Euro-Celtique, S.A. Immediate release tablet cores of insoluble drugs having sustained-release coating
US6210714B1 (en) 1993-11-23 2001-04-03 Euro-Celtique S.A. Immediate release tablet cores of acetaminophen having sustained-release coating
US5843544A (en) 1994-02-07 1998-12-01 E. Khashoggi Industries Articles which include a hinged starch-bound cellular matrix
US5776388A (en) 1994-02-07 1998-07-07 E. Khashoggi Industries, Llc Methods for molding articles which include a hinged starch-bound cellular matrix
US5705203A (en) 1994-02-07 1998-01-06 E. Khashoggi Industries Systems for molding articles which include a hinged starch-bound cellular matrix
CA2145497A1 (en) * 1994-05-10 1995-11-11 Subramaniam Mahadevan Protected feed product
US5596080A (en) * 1994-10-03 1997-01-21 E. I. Du Pont De Nemours And Company Crosslinking processes/agents for zein
US5733575A (en) * 1994-10-07 1998-03-31 Bpsi Holdings, Inc. Enteric film coating compositions, method of coating therewith, and coated forms
US5736178A (en) * 1995-05-02 1998-04-07 Opta Food Ingredients, Inc. Colloidal dispersions of gluten, method of making and use therefor
US6197199B1 (en) 1995-09-05 2001-03-06 Mcardle Blaise Use of protein-polysaccharide complex in removal of contaminants
US5942123A (en) * 1995-09-05 1999-08-24 Mcardle; Blaise Method of using a filter aid protein-polysaccharide complex composition
US6168857B1 (en) 1996-04-09 2001-01-02 E. Khashoggi Industries, Llc Compositions and methods for manufacturing starch-based compositions
US5939356A (en) * 1996-06-21 1999-08-17 Southwest Research Institute Controlled release coated agricultural products
DE69739165D1 (de) * 1996-07-08 2009-01-29 Penwest Pharmaceuticals Co Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe
EP0946152B1 (de) * 1996-12-18 2001-11-14 Isocell Biodegradierbare prolaminkapsel
US6020008A (en) * 1997-02-14 2000-02-01 Wm. Wrigley Jr. Company Prolamine miscible blends
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US20040029962A1 (en) * 1997-12-12 2004-02-12 Chih-Ming Chen HMG-COA reductase inhibitor extended release formulation
US20060141036A1 (en) * 1997-12-12 2006-06-29 Andrx Labs Llc HMG-CoA reductase inhibitor extended release formulation
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
NZ505193A (en) 1997-12-22 2003-03-28 Euro Celtique S Opioid agonist/antagonist combinations
UA53774C2 (uk) * 1997-12-22 2003-02-17 Еро-Селтік, С.А. Спосіб запобігання зловживанню лікарськими формами, що містять опіоїди
US20020034549A1 (en) * 1998-04-02 2002-03-21 Nathaniel T. Becker Modified starch coating
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US8293277B2 (en) * 1998-10-01 2012-10-23 Alkermes Pharma Ireland Limited Controlled-release nanoparticulate compositions
US20080213378A1 (en) * 1998-10-01 2008-09-04 Elan Pharma International, Ltd. Nanoparticulate statin formulations and novel statin combinations
WO2000018374A1 (en) * 1998-10-01 2000-04-06 Elan Pharma International, Ltd. Controlled release nanoparticulate compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
US20050048120A1 (en) * 1998-11-04 2005-03-03 Edgren David Emil Dosage form comprising self-destructive membrane
US7459283B2 (en) 2002-02-04 2008-12-02 Elan Pharma International Limited Nanoparticulate compositions having lysozyme as a surface stabilizer
US6969529B2 (en) * 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6419960B1 (en) 1998-12-17 2002-07-16 Euro-Celtique S.A. Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
US6197353B1 (en) 1998-12-24 2001-03-06 Opta Food Ingredients, Inc. Gluten-derived colloidal dispersions, edible coatings therefrom and method of making
US6174559B1 (en) 1998-12-24 2001-01-16 Opta Food Ingredients, Inc. Gluten-derived colloidal dispersions and edible coatings therefrom and method of making
KR100330491B1 (ko) * 1999-03-12 2002-04-01 김성봉 자연분해가 가능한 방수코팅 용기의 제조방법
AU762291B2 (en) * 1999-09-30 2003-06-19 Penwest Pharmaceutical Co. Sustained release matrix systems for highly soluble drugs
US6395198B1 (en) 1999-10-01 2002-05-28 Mcardle Biaise Anti-caking and anti-dusting composition and corresponding methods
CN1407884B (zh) 1999-10-29 2012-06-20 欧罗赛铁克股份有限公司 控释氢可酮制剂
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US8771740B2 (en) * 1999-12-20 2014-07-08 Nicholas J. Kerkhof Process for producing nanoparticles by spray drying
ES2326730T3 (es) * 2000-02-08 2009-10-19 Euro-Celtique S.A. Formulaciones orales de agonistas opioides resistentes a manipulaciones indebidas.
IL151058A0 (en) 2000-02-08 2003-04-10 Euro Celtique Sa Controlled-release compositions containing opioid agonist and antagonist
SE0001151D0 (sv) * 2000-03-31 2000-03-31 Amarin Dev Ab Method for producing a controlled-release composition
US20040156872A1 (en) * 2000-05-18 2004-08-12 Elan Pharma International Ltd. Novel nimesulide compositions
US7276249B2 (en) * 2002-05-24 2007-10-02 Elan Pharma International, Ltd. Nanoparticulate fibrate formulations
US7198795B2 (en) * 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
US6733783B2 (en) * 2000-10-30 2004-05-11 Euro-Celtique S.A. Controlled release hydrocodone formulations
US20020106408A1 (en) * 2000-12-01 2002-08-08 Johnatan Bacon Prolamin-based sustained-release compositions and delayed-onset compositions
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
JP4522652B2 (ja) 2001-05-11 2010-08-11 エンドー ファーマシューティカルズ， インコーポレイティド 乱用防止制御放出オピオイド投薬形態
ES2319620T3 (es) * 2001-07-18 2009-05-11 Euro-Celtique S.A. Conbinaciones farmaceuticas de oxicodona y naloxona.
AU2002324624A1 (en) 2001-08-06 2003-02-24 Euro-Celtique S.A. Sequestered antagonist formulations
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
DK1414451T3 (da) 2001-08-06 2009-08-10 Euro Celtique Sa Opioidagonistformuleringer med frigivelig og sekvenstreret antagonist
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20090088443A1 (en) * 2002-02-15 2009-04-02 Julius Remenar Novel crystalline forms of conazoles and methods of making and using the same
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
CA2477923C (en) * 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
EP2425823A1 (de) 2002-04-05 2012-03-07 Euro-Celtique S.A. Pharmazeutische Zubereitung mit Oxycodon und Naloxon
US20070264348A1 (en) * 2002-05-24 2007-11-15 Elan Pharma International, Ltd. Nanoparticulate fibrate formulations
US6733578B2 (en) 2002-06-20 2004-05-11 Wm. Wrigley Jr. Company Plasticized prolamine compositions
CN100360117C (zh) 2002-06-21 2008-01-09 转化医药公司 具有提高的溶出度的药物组合物
US6858238B2 (en) * 2002-06-26 2005-02-22 Wm. Wrigley Jr. Company Chewing gum products including prolamine blends
US8557291B2 (en) 2002-07-05 2013-10-15 Collegium Pharmaceutical, Inc. Abuse-deterrent pharmaceutical compositions of opioids and other drugs
US10004729B2 (en) 2002-07-05 2018-06-26 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US8840928B2 (en) 2002-07-05 2014-09-23 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
JP4694207B2 (ja) 2002-07-05 2011-06-08 コルジウム ファーマシューティカル， インコーポレイテッド オピオイドおよび他の薬物に関する乱用抑止性の薬学的組成物
JP4776229B2 (ja) * 2002-07-16 2011-09-21 エラン ファーマ インターナショナル，リミティド 安定なナノ粒子活性物質の液体投与組成物
CN1727471B (zh) * 2002-09-20 2013-03-06 中国科学院上海有机化学研究所 植物源性醇溶蛋白基质薄膜的用途
WO2004026283A1 (en) 2002-09-20 2004-04-01 Alpharma, Inc. Sequestering subunit and related compositions and metohds
AU2003267231A1 (en) * 2002-09-20 2004-04-08 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
EP1558211A2 (de) * 2002-10-30 2005-08-03 Pharmacia Corporation Orale tabletten mit verlängerter freisetzung und verfahren für deren herstellung sowie verwendung derselben
US20040086595A1 (en) * 2002-10-31 2004-05-06 Jingping Liu Plasticized prolamine compositions
AU2003295846A1 (en) * 2002-11-26 2004-06-18 Transform Pharmaceuticals, Inc. Pharmaceutical formulations of celcoxib
AU2003291828A1 (en) * 2002-11-27 2004-06-23 The University Of Georgia Research Foundation, Inc. Microspheres and related processes and pharmaceutical compositions
WO2004054542A2 (en) 2002-12-13 2004-07-01 Durect Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
EP2339328A3 (de) 2002-12-30 2011-07-13 Transform Pharmaceuticals, Inc. Pharmazeutische kokristallisierte Celecoxib-Zusammensetzungen
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
WO2004093819A2 (en) 2003-04-21 2004-11-04 Euro-Celtique, S.A. Tamper resistant dosage form comprising co-extruded, adverse agent particles and process of making same
KR100473422B1 (ko) * 2003-06-12 2005-03-14 박원봉 렉틴 함유 천연물의 장용성 코팅용 조성물
KR100511086B1 (ko) * 2003-09-17 2005-08-30 삼성정밀화학 주식회사 장용성의 수계 분산 히드록시프로필 메틸셀룰로오스프탈레이트 나노입자의 제조방법
EP1663229B1 (de) 2003-09-25 2010-04-14 Euro-Celtique S.A. Pharmazeutische kombinationen von hydrocodon und naltrexon
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
US8883204B2 (en) 2003-12-09 2014-11-11 Purdue Pharma L.P. Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
DK1691892T3 (da) * 2003-12-09 2007-06-25 Euro Celtique Sa Anbrudsbestandig, coekstruderet doseringsform, der indeholder et aktivt middel og et modvirkende middel, og fremgangsmåde til fremstilling af samme
EP2343073A3 (de) 2003-12-11 2011-10-12 Sepracor Inc. Kombination eines Beruhigungsmittels und eines Neurotransmittermodulators und Verfahren zur Verbesserung der Schlafqualität und Behandlung von Depressionen
TW201509943A (zh) * 2004-03-30 2015-03-16 Euro Celtique Sa 含有小於２５ｐｐｍ１４-羥可待因酮之羥可酮鹽酸鹽之組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝
CN1938004B (zh) 2004-03-30 2011-12-21 欧洲凯尔特公司 包含吸附剂和不利剂的抗篡改剂型
EP1604667A1 (de) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioide zur Behandlung des Restless Leg Syndroms
EP1604666A1 (de) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
LT1765292T (lt) 2004-06-12 2018-01-10 Collegium Pharmaceutical, Inc. Nuo piktnaudžiavimo apsaugotos vaistų formos
US20100301254A1 (en) * 2004-06-23 2010-12-02 University Of Maine System Board Of Trustees Barrier compositions and articles produced with the compositions
US7737200B2 (en) 2004-06-23 2010-06-15 University Of Maine System Board Of Trustees Barrier compositions and articles produced with the compositions
AU2005282784B2 (en) 2004-09-01 2008-06-19 Euro-Celtique S.A. Opioid dosage forms having dose proportional steady state Cave and AUC and less than dose proportional single dose Cmax
US20070259045A1 (en) * 2005-01-28 2007-11-08 Euro-Celtique S.A. Alcohol Resistant Dosage Forms
US20060188611A1 (en) * 2005-02-18 2006-08-24 Emine Unlu Edible pet chew
EP1695700A1 (de) * 2005-02-28 2006-08-30 Euro-Celtique S.A. Darreichungsform enthaltend Oxycodon und Naloxon
EP1702558A1 (de) 2005-02-28 2006-09-20 Euro-Celtique S.A. Verfahren und Vorrichtung zur Darmtätigkeitserfassung
KR20120107533A (ko) * 2005-11-28 2012-10-02 마리누스 파마슈티컬스 ｇａｎａｘｏｌｏｎｅ 제형, 이의 제조방법 및 용도
EP1981560B1 (de) * 2006-01-05 2010-09-08 Med Institute, Inc. Zein-beschichtete medizinische vorrichtung
EP1813276A1 (de) * 2006-01-27 2007-08-01 Euro-Celtique S.A. Manipulationssichere Dosierformen
PL2526932T3 (pl) 2006-06-19 2017-12-29 Alpharma Pharmaceuticals Llc Kompozycja farmaceutyczna
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
EP2101735A2 (de) 2006-11-28 2009-09-23 Marinus Pharmaceuticals, Inc. Nanoteilchenförmige formulierungen und verfahren zur herstellung und verwendung
GB0624880D0 (en) * 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics
WO2009042114A2 (en) 2007-09-21 2009-04-02 The Johns Hopkins University Phenazine derivatives and uses thereof
WO2009067431A2 (en) 2007-11-20 2009-05-28 Cook Incorporated Controlled drug delivery using a zein layer modified with levulinic acid
WO2009088414A2 (en) 2007-12-06 2009-07-16 Durect Corporation Oral pharmaceutical dosage forms
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US8697098B2 (en) 2011-02-25 2014-04-15 South Dakota State University Polymer conjugated protein micelles
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
SG174286A1 (en) 2009-03-10 2011-10-28 Euro Celtique Sa Immediate release pharmaceutical compositions comprising oxycodone and naloxone
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
PT2826467T (pt) 2010-12-22 2017-10-25 Purdue Pharma Lp Formas envolvidas de dosamento de libertação controlada resistentes à adulteração
CA2822769C (en) 2010-12-23 2016-10-04 Purdue Pharma L.P. Tamper resistant solid oral dosage forms
EP2678007A4 (de) 2011-02-25 2015-08-12 Univ South Dakota Proteinnanoträger zur topischen verabreichung
CN103945830B (zh) * 2011-02-25 2017-06-06 南达科他州立大学 缀合蛋白的聚合物胶束
BR112014000934A2 (pt) 2011-07-14 2017-02-14 Poet Res Inc composições de prolamina à base de água, processos de produção de composições de prolamina à base de água e aplicações das mesmas
EP2625966A1 (de) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanopartikel mit einem pflanzlichen hydrophoben Protein und wassermischbare nichtflüchtige organische Lösung sowie Verwendungen davon
DE112013002074T5 (de) 2012-04-17 2015-01-29 Purdue Pharma L.P. Systeme und Methoden zur Behandlung einer Opioid-induzierten unerwünschten pharmakodynamischen Reaktion
EA028092B1 (ru) 2012-07-16 2017-10-31 Родс Текнолоджис Способ усовершенствованного синтеза опиоидов
US20150259355A1 (en) 2012-07-16 2015-09-17 Rhodes Technologies Process for improved opioid synthesis
SG11201506064UA (en) 2013-02-05 2015-08-28 Purdue Pharma Lp Tamper resistant pharmaceutical formulations
US9273227B2 (en) 2013-03-06 2016-03-01 Poet Research, Inc. Waterborne aqueous-alcohol soluble protein compositions, applications, and methods
TW201521769A (zh) 2013-03-15 2015-06-16 Durect Corp 具有流變改質劑以減少溶解變異性之組成物
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
WO2015011189A1 (en) 2013-07-23 2015-01-29 Euro-Celtique S.A. A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
GB2517000B (en) 2013-08-02 2018-05-09 Johnson Matthey Plc Process for the synthesis of oxymorphone alkaloid and oxymorphone salts
ES2672795T3 (es) 2014-01-15 2018-06-18 Rhodes Technologies Proceso para la síntesis mejorada de oximorfona
AU2015207733A1 (en) 2014-01-15 2016-07-14 Rhodes Technologies Process for improved oxycodone synthesis
US9062063B1 (en) 2014-03-21 2015-06-23 Johnson Matthey Public Limited Company Forms of oxymorphone hydrochloride
US9849124B2 (en) 2014-10-17 2017-12-26 Purdue Pharma L.P. Systems and methods for treating an opioid-induced adverse pharmacodynamic response
CA2936746C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US9918979B2 (en) 2015-01-29 2018-03-20 Johnson Matthey Public Limited Company Process of preparing low ABUK oxymorphone hydrochloride
EP3256004A1 (de) 2015-02-13 2017-12-20 Mars, Incorporated Zuführsystem für haustierfutter
EP3324975B1 (de) 2015-07-22 2022-05-18 John Hsu Zusammensetzung mit einem therapeutischen wirkstoff und einem respiratorischen stimulans und verfahren zu deren verwendung
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
GB201715660D0 (en) 2017-09-27 2017-11-08 Mars Inc Jaw assembly
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
US20230143910A1 (en) * 2020-04-16 2023-05-11 Akorn Technology, Inc. Edible films and coatings employing water soluble corn prolamin and other functional ingredients
WO2021249621A1 (en) 2020-06-09 2021-12-16 Traceless Materials Gmbh Process for producing water-resistant films from corn gluten meal
CN112245409B (zh) * 2020-10-23 2022-03-15 安徽大学 一种植物蛋白-熊去氧胆酸缓释纳米粒复合微囊及其制备方法
CN112790370B (zh) * 2020-12-18 2023-07-28 上海交通大学 一种植物蛋白面团的制备方法
LU500976B1 (en) 2021-12-09 2023-06-09 Traceless Mat Gmbh Process for producing a thermoplastic material for use as a powder or granulate for further processing such as injection moulding or coating
LU500975B1 (en) 2021-12-09 2023-06-09 Traceless Mat Gmbh Process for producing a thermoplastic material for use as a film or as a flexible coating
CN115012227B (zh) * 2022-07-14 2024-03-26 江南大学 一种利用生物大分子制备疏水纺织品的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2272488A (en) * 1942-02-10 Process fok the production of zein
GB516295A (en) * 1937-08-18 1939-12-29 Corn Prod Refining Co Improvements in and relating to the precipitation of zein
US2377237A (en) * 1940-08-03 1945-05-29 Corn Prod Refining Co Zein dispersions and processes of making same
US2676169A (en) * 1951-09-26 1954-04-20 Corn Prod Refining Co Method of treating zein
US2791509A (en) * 1954-06-24 1957-05-07 Horace B Cosler Method of producing zein-coated confectionery
US2772488A (en) * 1955-07-20 1956-12-04 Meltzer Jack Shoe having covered insole body and nailed-on heel
US3092553A (en) * 1959-01-30 1963-06-04 Jr Carl E Fisher Pharmaceutical preparations and method and apparatus for making same
DE1228757B (de) * 1962-06-28 1966-11-17 Haessle Ab Verfahren zur Herstellung eines in Wasser und Magensaft rasch zerfallenden UEberzuges auf festen Arzneiformen
US3370054A (en) * 1965-03-05 1968-02-20 Interchem Corp Zein prepared by strong alkali hydrolysis of aqueous alcoholic zein solutions and subsequent acid precipitation of the alkali
US3365365A (en) * 1965-08-09 1968-01-23 Hoffmann La Roche Repeat action pharmaceutical compositions in the form of discrete beadlets
FR2624351B1 (fr) * 1987-12-15 1991-11-22 Rhone Poulenc Sante Compositions degradables par voie enzymatique utilisables pour l'enrobage d'additifs alimentaires destines aux ruminants
WO1990003123A2 (en) * 1988-09-19 1990-04-05 Enzytech, Inc. Hydrophobic protein microparticles and preparation thereof
US4931295A (en) * 1988-12-02 1990-06-05 Wm. Wrigley Jr. Company Chewing gum containing high-potency sweetener particles with modified zein coating
CA1339632C (en) * 1989-02-15 1998-01-20 Robert A. Payne Method of producing an aqueous zein solution
ES2084712T3 (es) * 1989-11-06 1996-05-16 Alkermes Inc Metodo para producir microesferas proteicas.
WO1991006227A1 (en) * 1989-11-06 1991-05-16 Opta Food Ingredients, Inc. Protein-based edible coatings

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NO932867L (no) 1994-02-14
CN1086144A (zh) 1994-05-04
US5324351A (en) 1994-06-28
JPH06172398A (ja) 1994-06-21
EP0585688A3 (de) 1994-08-03
PL300087A1 (en) 1994-04-18
EP0585688A2 (de) 1994-03-09
IL106647A0 (en) 1993-12-08
KR940005265A (ko) 1994-03-21
ZA935869B (en) 1994-03-09
ATE172224T1 (de) 1998-10-15
US5356467A (en) 1994-10-18
EP0585688B1 (de) 1998-10-14
MX9304900A (es) 1994-06-30
DE69321538D1 (de) 1998-11-19
CA2103635A1 (en) 1994-02-14
NO932867D0 (no) 1993-08-12

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