DE69309430T2 - Vorrichtung und Verfahren zum Brechen einer Ampulle - Google Patents
Vorrichtung und Verfahren zum Brechen einer AmpulleInfo
- Publication number
- DE69309430T2 DE69309430T2 DE69309430T DE69309430T DE69309430T2 DE 69309430 T2 DE69309430 T2 DE 69309430T2 DE 69309430 T DE69309430 T DE 69309430T DE 69309430 T DE69309430 T DE 69309430T DE 69309430 T2 DE69309430 T2 DE 69309430T2
- Authority
- DE
- Germany
- Prior art keywords
- ampoule
- parts
- sample
- swab
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003708 ampul Substances 0.000 title claims description 83
- 238000000034 method Methods 0.000 title description 2
- 239000000523 sample Substances 0.000 claims description 47
- 238000012360 testing method Methods 0.000 claims description 19
- 239000003153 chemical reaction reagent Substances 0.000 claims description 13
- 239000012472 biological sample Substances 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 7
- 230000001681 protective effect Effects 0.000 description 27
- 239000002250 absorbent Substances 0.000 description 17
- 230000002745 absorbent Effects 0.000 description 17
- 239000007788 liquid Substances 0.000 description 14
- 241001505901 Streptococcus sp. 'group A' Species 0.000 description 11
- 239000002609 medium Substances 0.000 description 8
- 239000000427 antigen Substances 0.000 description 6
- 102000036639 antigens Human genes 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 230000032258 transport Effects 0.000 description 6
- BZEPQNMASTUAMY-UHFFFAOYSA-N pyrrolidonyl-β-naphthylamide Chemical compound C=1C=C2C=CC=CC2=CC=1NC(=O)C1CCC(=O)N1 BZEPQNMASTUAMY-UHFFFAOYSA-N 0.000 description 5
- 239000002253 acid Substances 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- PLXMOAALOJOTIY-FPTXNFDTSA-N Aesculin Natural products OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1Oc2cc3C=CC(=O)Oc3cc2O PLXMOAALOJOTIY-FPTXNFDTSA-N 0.000 description 3
- WNBCMONIPIJTSB-BGNCJLHMSA-N Cichoriin Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)c1c(O)cc2c(OC(=O)C=C2)c1 WNBCMONIPIJTSB-BGNCJLHMSA-N 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- XHCADAYNFIFUHF-TVKJYDDYSA-N esculin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC2=C1OC(=O)C=C2 XHCADAYNFIFUHF-TVKJYDDYSA-N 0.000 description 3
- 229940093496 esculin Drugs 0.000 description 3
- AWRMZKLXZLNBBK-UHFFFAOYSA-N esculin Natural products OC1OC(COc2cc3C=CC(=O)Oc3cc2O)C(O)C(O)C1O AWRMZKLXZLNBBK-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 206010018612 Gonorrhoea Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 description 2
- 102000035195 Peptidases Human genes 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 241000725643 Respiratory syncytial virus Species 0.000 description 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
- 206010046443 Urethral discharge Diseases 0.000 description 2
- 238000004737 colorimetric analysis Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 208000001786 gonorrhea Diseases 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 235000019833 protease Nutrition 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000003248 secreting effect Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 235000010288 sodium nitrite Nutrition 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 108020003215 DNA Probes Proteins 0.000 description 1
- 239000003298 DNA probe Substances 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- QIAFMBKCNZACKA-UHFFFAOYSA-N Hippuric acid Natural products OC(=O)CNC(=O)C1=CC=CC=C1 QIAFMBKCNZACKA-UHFFFAOYSA-N 0.000 description 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 1
- 241000588653 Neisseria Species 0.000 description 1
- 241000588652 Neisseria gonorrhoeae Species 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 description 1
- 108020004518 RNA Probes Proteins 0.000 description 1
- 239000003391 RNA probe Substances 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193990 Streptococcus sp. 'group B' Species 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 229960004308 acetylcysteine Drugs 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000006163 transport media Substances 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67B—APPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
- B67B7/00—Hand- or power-operated devices for opening closed containers
- B67B7/92—Hand- or power-operated devices for opening closed containers by breaking, e.g. for ampoules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0096—Casings for storing test samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/22—Means for packing or storing viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/38—Swabs having a stick-type handle, e.g. cotton tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N2001/028—Sampling from a surface, swabbing, vaporising
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Sustainable Development (AREA)
- Mechanical Engineering (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Devices For Opening Bottles Or Cans (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/050,521 US5313959A (en) | 1993-04-21 | 1993-04-21 | Device and method for breaking an ampoule |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69309430D1 DE69309430D1 (de) | 1997-05-07 |
| DE69309430T2 true DE69309430T2 (de) | 1997-10-23 |
Family
ID=21965723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69309430T Expired - Fee Related DE69309430T2 (de) | 1993-04-21 | 1993-12-14 | Vorrichtung und Verfahren zum Brechen einer Ampulle |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5313959A (https=) |
| EP (1) | EP0621232B1 (https=) |
| JP (1) | JP2516734B2 (https=) |
| AU (1) | AU662086B2 (https=) |
| CA (1) | CA2110834C (https=) |
| DE (1) | DE69309430T2 (https=) |
| SG (1) | SG45463A1 (https=) |
| TW (1) | TW256770B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102022212454A1 (de) * | 2022-11-22 | 2024-05-23 | PharmaMedia Dr. Müller GmbH | Vorrichtung zur Bereitstellung und Handhabung eines sterilen flüssigen Mediums, Verfahren zur Bereitstellung eines flüssigen Kulturmediums und Anwendung einer entsprechenden Vorrichtung zur Probennahme in Reinräumen oder Isolatoren |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD355970S (en) | 1993-06-28 | 1995-02-28 | Becton, Dickinson And Company | Culturette sleeve for breaking an ampoule |
| CA2131489C (en) * | 1993-09-23 | 1997-01-21 | James F. Monthony | Collecting and transport system |
| WO1996014570A1 (en) * | 1994-11-07 | 1996-05-17 | Idexx Laboratories, Inc. | Self-contained signal generating sampling device and methods of use of same |
| US6458322B1 (en) | 2000-09-08 | 2002-10-01 | Bioavailability Systems, Llc | Method for simplified shipping of clinical specimens and optional direct analysis |
| JP4642277B2 (ja) | 2001-06-21 | 2011-03-02 | 株式会社ジーシー | 唾液の前処理用具及び唾液の前処理方法 |
| US6712252B2 (en) | 2001-08-31 | 2004-03-30 | Starr Systems, Llc | Method of opening an ampoule |
| US7285246B1 (en) * | 2003-08-19 | 2007-10-23 | Akers Acquisition Sub, Inc. | Hand-held fluid analyzer |
| US20050131314A1 (en) * | 2003-11-17 | 2005-06-16 | Hird Robert F. | Methods and apparatus for the rapid detection of microorganisms collected from infected sites |
| JP2007524493A (ja) * | 2003-12-05 | 2007-08-30 | ゲィリー ツァワー | 封入式打開手段 |
| US20050288606A1 (en) * | 2004-06-25 | 2005-12-29 | Continental Plastic Corp | Culture swab with protective cap and safety pin |
| US8357538B2 (en) * | 2007-04-06 | 2013-01-22 | Qiagen Gaithersburg, Inc. | Automated assay and system |
| WO2010129727A1 (en) * | 2009-05-06 | 2010-11-11 | 3M Innovative Properties Company | Coated substrates comprising a cell extractant and biodetection methods thereof |
| US20120094281A1 (en) * | 2009-05-06 | 2012-04-19 | Raj Rajagopal | Articles with shell structures including a cell extractant and biodetection methods thereof |
| US20120082977A1 (en) * | 2009-05-06 | 2012-04-05 | Raj Rajagopal | Articles with matrix comprising a cell extractant and biodetection methods thereof |
| US20110146418A1 (en) * | 2009-10-02 | 2011-06-23 | Brevnov Maxim G | Sample Preparation Devices and Methods |
| CN104936699A (zh) * | 2013-01-22 | 2015-09-23 | 贝克顿·迪金森公司 | 使自动开盖便利的双条形码标注 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3450129A (en) * | 1966-07-06 | 1969-06-17 | Medical Supply Co | Swabbing unit |
| US3891331A (en) * | 1974-06-14 | 1975-06-24 | Marion Health & Safety Inc | Unit for dispensing liquid from a frangible ampoule |
| US3924623A (en) * | 1974-11-04 | 1975-12-09 | Marion Health And Safety Inc | Tip for applicator swab |
| US4014748A (en) * | 1975-12-22 | 1977-03-29 | Marion Laboratories, Inc. | Anaerobic culture collecting and transporting apparatus |
| US4023934A (en) * | 1975-12-22 | 1977-05-17 | Marion Laboratories, Inc. | Color indicator apparatus for presence of oxygen |
| US4211323A (en) * | 1978-12-01 | 1980-07-08 | California Medical Developments, Inc. | Disposable diagnostic swab having a stored culture medium |
| US4196167A (en) * | 1978-12-26 | 1980-04-01 | California Medical Developments, Inc. | Drug detection device |
| US4311792A (en) * | 1980-04-14 | 1982-01-19 | Marion Health And Safety, Inc. | Culture collecting and transporting unit |
| US4353868A (en) * | 1981-05-29 | 1982-10-12 | Sherwood Medical Industries Inc. | Specimen collecting device |
| US4604360A (en) * | 1983-01-19 | 1986-08-05 | Hounsell Melvin W | Culture transport apparatus |
| US4586604A (en) * | 1984-06-28 | 1986-05-06 | Continental Plastic Corporation | Culture collection instrument and sealed swab holder therefor |
| US4637139A (en) * | 1984-12-07 | 1987-01-20 | Fu Chen | Ampoule cutter |
| US5238649A (en) * | 1988-02-09 | 1993-08-24 | Nason Frederic L | Specimen test unit |
| NO168369C (no) * | 1989-09-18 | 1992-02-12 | Bionor As | Oppsamlings- og transportsystem for kulturer av mikroorganismer |
| CA2044422C (en) * | 1990-07-10 | 1995-02-07 | Hans-Joachim Burkardt | Transport system for conveying biological samples |
-
1993
- 1993-04-21 US US08/050,521 patent/US5313959A/en not_active Expired - Lifetime
- 1993-12-07 CA CA002110834A patent/CA2110834C/en not_active Expired - Fee Related
- 1993-12-14 SG SG1996009623A patent/SG45463A1/en unknown
- 1993-12-14 EP EP93120103A patent/EP0621232B1/en not_active Expired - Lifetime
- 1993-12-14 DE DE69309430T patent/DE69309430T2/de not_active Expired - Fee Related
- 1993-12-28 JP JP5338130A patent/JP2516734B2/ja not_active Expired - Lifetime
-
1994
- 1994-01-24 AU AU53959/94A patent/AU662086B2/en not_active Ceased
- 1994-01-28 TW TW083100736A patent/TW256770B/zh not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102022212454A1 (de) * | 2022-11-22 | 2024-05-23 | PharmaMedia Dr. Müller GmbH | Vorrichtung zur Bereitstellung und Handhabung eines sterilen flüssigen Mediums, Verfahren zur Bereitstellung eines flüssigen Kulturmediums und Anwendung einer entsprechenden Vorrichtung zur Probennahme in Reinräumen oder Isolatoren |
| WO2024109992A1 (de) * | 2022-11-22 | 2024-05-30 | Pharmamedia Dr. Mueller Gmbh | Vorrichtung zur bereitstellung und handhabung eines sterilen flüssigen mediums, verfahren zur bereitstellung eines flüssigen kulturmediums und anwendung einer entsprechenden vorrichtung zur probennahme in reinräumen oder isolatoren |
Also Published As
| Publication number | Publication date |
|---|---|
| AU662086B2 (en) | 1995-08-17 |
| SG45463A1 (en) | 1998-01-16 |
| TW256770B (https=) | 1995-09-11 |
| AU5395994A (en) | 1994-10-27 |
| JP2516734B2 (ja) | 1996-07-24 |
| US5313959A (en) | 1994-05-24 |
| EP0621232B1 (en) | 1997-04-02 |
| CA2110834A1 (en) | 1994-10-22 |
| EP0621232A1 (en) | 1994-10-26 |
| DE69309430D1 (de) | 1997-05-07 |
| JPH06312787A (ja) | 1994-11-08 |
| CA2110834C (en) | 2000-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |