DE69300162D1 - 2-Amino-N-[[[4-(aminocarbonyl)pyrimidin-2-yl]amino]alkyl]-pyrimidin-4-carbonsäureamidderivate, ihre Herstellung und ihre Anwendung in der Therapeutica. - Google Patents

2-Amino-N-[[[4-(aminocarbonyl)pyrimidin-2-yl]amino]alkyl]-pyrimidin-4-carbonsäureamidderivate, ihre Herstellung und ihre Anwendung in der Therapeutica.

Info

Publication number
DE69300162D1
DE69300162D1 DE69300162T DE69300162T DE69300162D1 DE 69300162 D1 DE69300162 D1 DE 69300162D1 DE 69300162 T DE69300162 T DE 69300162T DE 69300162 T DE69300162 T DE 69300162T DE 69300162 D1 DE69300162 D1 DE 69300162D1
Authority
DE
Germany
Prior art keywords
amino
group
therapeutics
alkyl
aminocarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69300162T
Other languages
English (en)
Other versions
DE69300162T2 (de
Inventor
Pascal George
Benoit Marabout
Jacques Froissant
Jean-Pierre Merly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9208199A external-priority patent/FR2693195B1/fr
Priority claimed from FR9215037A external-priority patent/FR2699171B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of DE69300162D1 publication Critical patent/DE69300162D1/de
Application granted granted Critical
Publication of DE69300162T2 publication Critical patent/DE69300162T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69300162T 1992-07-03 1993-06-22 2-Amino-N-[[[4-(aminocarbonyl)pyrimidin-2-yl]amino]alkyl]-pyrimidin-4-carbonsäureamidderivate, ihre Herstellung und ihre Anwendung in der Therapeutica. Expired - Lifetime DE69300162T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9208199A FR2693195B1 (fr) 1992-07-03 1992-07-03 Dérivés de 2-amino-N-[[[(4-aminocarbonyl)pyrimidin-2-yl]amino]alkyl] pyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.
FR9215037A FR2699171B1 (fr) 1992-12-14 1992-12-14 Dérivés de 2-amino-N[[[4-aminocarbonyl) pyrimidin-2-yl]amino]alkyl]pyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.

Publications (2)

Publication Number Publication Date
DE69300162D1 true DE69300162D1 (de) 1995-06-29
DE69300162T2 DE69300162T2 (de) 1995-11-02

Family

ID=26229565

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69300162T Expired - Lifetime DE69300162T2 (de) 1992-07-03 1993-06-22 2-Amino-N-[[[4-(aminocarbonyl)pyrimidin-2-yl]amino]alkyl]-pyrimidin-4-carbonsäureamidderivate, ihre Herstellung und ihre Anwendung in der Therapeutica.

Country Status (21)

Country Link
US (1) US5330985A (de)
EP (1) EP0577470B1 (de)
JP (1) JP3285421B2 (de)
KR (1) KR940005619A (de)
CN (1) CN1100416A (de)
AT (1) ATE123025T1 (de)
AU (1) AU660815B2 (de)
CA (1) CA2099556A1 (de)
CZ (1) CZ282079B6 (de)
DE (1) DE69300162T2 (de)
DK (1) DK0577470T3 (de)
ES (1) ES2073951T3 (de)
FI (1) FI933064A (de)
HU (2) HUT65533A (de)
IL (1) IL106213A (de)
MX (1) MX9303976A (de)
NO (1) NO932418L (de)
NZ (1) NZ248051A (de)
PL (1) PL172583B1 (de)
RU (1) RU2111963C1 (de)
SK (1) SK69993A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4425143A1 (de) * 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
FR2744722B1 (fr) * 1996-02-14 1998-03-13 Synthelabo Devires de 2-((3-(piperazin-1-yl)propyl)amino)pyrimidine-4- carboxamide et leur application en therapeutique
EP1075486A1 (de) * 1998-05-06 2001-02-14 Duke University Verfahren zur behandlung von syndromen der niere und der unteren harnwege
RU2377976C2 (ru) * 2004-07-29 2010-01-10 Санофи-Авентис ФАРМАЦЕВТИЧЕСКАЯ МНОГОСЛОЙНАЯ ТАБЛЕТКА ДЛЯ КОНТРОЛИРУЕМОГО ВЫСВОБОЖДЕНИЯ АКТИВНЫХ ИНГРЕДИЕНТОВ С РАСТВОРИМОСТЬЮ, В ВЫСОКОЙ СТЕПЕНИ ЗАВИСЯЩЕЙ ОТ pH
US9113629B2 (en) * 2013-03-15 2015-08-25 Dow Agrosciences Llc 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618436B1 (fr) * 1987-07-23 1989-10-27 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique
JP2814600B2 (ja) * 1989-08-31 1998-10-22 正幸 石川 排尿障害治療剤
JPH078795B2 (ja) * 1989-09-06 1995-02-01 日立化成工業株式会社 排尿障害治療剤
FR2656609B1 (fr) * 1989-12-28 1992-03-27 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2675799B1 (fr) * 1991-04-24 1993-12-24 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2678272B1 (fr) * 1991-06-27 1994-01-14 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2678271B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
AU4171293A (en) 1994-01-06
JP3285421B2 (ja) 2002-05-27
EP0577470A1 (de) 1994-01-05
PL172583B1 (pl) 1997-10-31
NO932418D0 (no) 1993-07-02
HU211462A9 (en) 1995-11-28
NO932418L (no) 1994-01-04
FI933064A0 (fi) 1993-07-02
IL106213A0 (en) 1993-11-15
CN1100416A (zh) 1995-03-22
CZ135193A3 (en) 1994-02-16
SK69993A3 (en) 1994-04-06
EP0577470B1 (de) 1995-05-24
JPH06100545A (ja) 1994-04-12
AU660815B2 (en) 1995-07-06
HUT65533A (en) 1994-06-28
ATE123025T1 (de) 1995-06-15
FI933064A (fi) 1994-01-04
PL299541A1 (en) 1994-01-10
DE69300162T2 (de) 1995-11-02
HU9301937D0 (en) 1993-09-28
US5330985A (en) 1994-07-19
MX9303976A (es) 1994-02-28
NZ248051A (en) 1994-10-26
DK0577470T3 (da) 1995-10-02
ES2073951T3 (es) 1995-08-16
RU2111963C1 (ru) 1998-05-27
KR940005619A (ko) 1994-03-21
CZ282079B6 (cs) 1997-05-14
CA2099556A1 (en) 1994-01-04
IL106213A (en) 1998-02-22

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR

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