DE69215694T2 - Benzamid-derivate - Google Patents

Benzamid-derivate

Info

Publication number
DE69215694T2
DE69215694T2 DE69215694T DE69215694T DE69215694T2 DE 69215694 T2 DE69215694 T2 DE 69215694T2 DE 69215694 T DE69215694 T DE 69215694T DE 69215694 T DE69215694 T DE 69215694T DE 69215694 T2 DE69215694 T2 DE 69215694T2
Authority
DE
Germany
Prior art keywords
chloro
methoxybenzamido
amino
endo
azabicyclo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69215694T
Other languages
German (de)
English (en)
Other versions
DE69215694D1 (de
Inventor
Yasuo Katsuyama-Shi Fukui-Ken 911 Ito
Nobuhiko Katsuyama-Shi Fukui-Ken 911 Iwasaki
Hideo Fukui-Shi Fukui-Ken 910 Kato
Hiroyuki Katsuyama-Shi Fukui-Ken 911 Nishino
Makoto Katsuyama-Shi Fukui-Ken 911 Takeshita
Shingo Katsuyama-Shi Fukui-Ken 911 Yasuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69215694D1 publication Critical patent/DE69215694D1/de
Publication of DE69215694T2 publication Critical patent/DE69215694T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69215694T 1991-02-15 1992-02-12 Benzamid-derivate Expired - Lifetime DE69215694T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4242591 1991-02-15
JP23375691 1991-08-22
PCT/JP1992/000134 WO1992014705A1 (en) 1991-02-15 1992-02-12 Benzamide derivative

Publications (2)

Publication Number Publication Date
DE69215694D1 DE69215694D1 (de) 1997-01-16
DE69215694T2 true DE69215694T2 (de) 1997-05-28

Family

ID=26382109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69215694T Expired - Lifetime DE69215694T2 (de) 1991-02-15 1992-02-12 Benzamid-derivate

Country Status (9)

Country Link
EP (1) EP0640601B1 (enExample)
KR (1) KR0159961B1 (enExample)
AT (1) ATE145906T1 (enExample)
CA (1) CA2103590C (enExample)
DE (1) DE69215694T2 (enExample)
DK (1) DK0640601T3 (enExample)
ES (1) ES2096073T3 (enExample)
TW (2) TW213460B (enExample)
WO (1) WO1992014705A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970702247A (ko) * 1994-03-30 1997-05-13 고야 마사시 벤조산 화합물 및 이들의 약제로서의 용도(benzoic acid compound and use thereof as medicine)
US5686441A (en) * 1995-08-04 1997-11-11 Syphar Laboratories, Inc. Penam sulfones as β-lactamase inhibitors
AU7001796A (en) * 1995-09-22 1997-04-09 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and medicinal use thereof
DE69818678T2 (de) * 1997-07-11 2004-07-15 Janssen Pharmaceutica N.V. (+)-norcisapride verwendbar bei 5-ht3 und 5-ht4 bedingten krankheiten
TW402591B (en) * 1997-07-11 2000-08-21 Janssen Pharmaceutica Nv Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
AR022338A1 (es) * 1999-02-04 2002-09-04 Hokuriku Pharmaceutical Un compuesto de benzamida, medicamento que lo contiene, y uso para la manufactura de un medicamento para el tratamiento o prevencion de una enfermedad digestiva o para mejorar la movilidad del tracto gastrointestinal.
US7049326B2 (en) 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects
US6750238B1 (en) 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs
AU2006201053B2 (en) * 2000-06-07 2008-01-31 Aryx Therapeutics Materials and methods for the treatment of gastroesophageal reflux disease
WO2001093849A2 (en) * 2000-06-07 2001-12-13 Aryx Therapeutics Treatment of gastroesophageal reflux disease using piperidine derivatives
HUP0201980A3 (en) * 2002-06-13 2008-06-30 Richter Gedeon Nyrt Process for preparing a benzamide derivative and intermediates thereof
US7244758B2 (en) 2003-05-30 2007-07-17 Neuromed Pharmaceuticals Ltd. N-type calcium channel blockers
US8524736B2 (en) 2004-01-07 2013-09-03 Armetheon, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US8138204B2 (en) 2004-01-07 2012-03-20 Aryx Therapeutics, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
DK2194053T3 (da) * 2004-01-07 2013-07-01 Armetheon Inc Methoxypiperidinderivater til brug i behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet.
ES2436100T3 (es) * 2005-08-31 2013-12-27 Armetheon, Inc. Métodos sintéticos y productos intermedios para compuestos estereoisoméricos útiles para el tratamiento de trastornos del sistema nervioso central y gastrointestinal
KR100976063B1 (ko) * 2007-03-16 2010-08-17 동아제약주식회사 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법
CN101402633A (zh) * 2007-09-11 2009-04-08 上海恒瑞医药有限公司 苯甲酰胺类衍生物、其制备方法及其在医药上的用途
TWI423967B (zh) 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US10570127B1 (en) 2018-11-05 2020-02-25 Renexxion, Llc Material and methods for the treatment of gastro-intestinal disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513631A (en) * 1976-02-17 1978-06-07 Gallardo Antonio Sa Piperidine derivatives
JPS5832878A (ja) * 1981-06-17 1983-02-25 ビ−チヤム・グレ−プ・ピ−エルシ− アルキルチオ誘導体、その製造法及びそれを含む医薬組成物
EP0099194A3 (en) * 1982-07-03 1984-04-11 Beecham Group Plc Novel benzamides
ZA854790B (en) * 1984-06-28 1986-02-26 Bristol Myers Co Pharmacologically active substituted benzamides
GB8527052D0 (en) * 1985-11-02 1985-12-04 Beecham Group Plc Compounds
US4870074A (en) * 1986-04-30 1989-09-26 Dainippon Pharmaceutical Co., Ltd. Substituted benzamide derivatives, for enhancing gastrointestinal motility
GB8718345D0 (en) * 1987-08-03 1987-09-09 Fordonal Sa N-substituted benzamides

Also Published As

Publication number Publication date
TW243449B (enExample) 1995-03-21
EP0640601A4 (en) 1994-03-07
ES2096073T3 (es) 1997-03-01
KR0159961B1 (ko) 1998-12-01
EP0640601A1 (en) 1995-03-01
WO1992014705A1 (en) 1992-09-03
ATE145906T1 (de) 1996-12-15
CA2103590C (en) 1999-06-01
CA2103590A1 (en) 1992-08-16
EP0640601B1 (en) 1996-12-04
DK0640601T3 (da) 1997-06-02
DE69215694D1 (de) 1997-01-16
TW213460B (enExample) 1993-09-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ABBOTT JAPAN CO.,LTD., TOKIO/TOKYO, JP