DE69212914D1 - Schnellsynthese und Screening von Peptidmimetika - Google Patents

Schnellsynthese und Screening von Peptidmimetika

Info

Publication number
DE69212914D1
DE69212914D1 DE69212914T DE69212914T DE69212914D1 DE 69212914 D1 DE69212914 D1 DE 69212914D1 DE 69212914 T DE69212914 T DE 69212914T DE 69212914 T DE69212914 T DE 69212914T DE 69212914 D1 DE69212914 D1 DE 69212914D1
Authority
DE
Germany
Prior art keywords
amino acids
gps
peptide
aliquots
mixts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69212914T
Other languages
English (en)
Other versions
DE69212914T2 (de
Inventor
Richard Dennis Dimarchi
Paul David Gesellchen
Rebecca Anne Owens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69212914D1 publication Critical patent/DE69212914D1/de
Application granted granted Critical
Publication of DE69212914T2 publication Critical patent/DE69212914T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69212914T 1991-06-18 1992-06-11 Schnellsynthese und Screening von Peptidmimetika Expired - Fee Related DE69212914T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71718491A 1991-06-18 1991-06-18

Publications (2)

Publication Number Publication Date
DE69212914D1 true DE69212914D1 (de) 1996-09-26
DE69212914T2 DE69212914T2 (de) 1997-02-13

Family

ID=24881038

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69212914T Expired - Fee Related DE69212914T2 (de) 1991-06-18 1992-06-11 Schnellsynthese und Screening von Peptidmimetika

Country Status (25)

Country Link
US (1) US5422426A (de)
EP (1) EP0519640B1 (de)
JP (1) JPH05194586A (de)
KR (1) KR100237126B1 (de)
CN (1) CN1038034C (de)
AT (1) ATE141611T1 (de)
AU (1) AU658636B2 (de)
BR (1) BR9202288A (de)
CA (1) CA2071061A1 (de)
CZ (1) CZ287710B6 (de)
DE (1) DE69212914T2 (de)
DK (1) DK0519640T3 (de)
ES (1) ES2093199T3 (de)
FI (1) FI922784A (de)
GR (1) GR3021295T3 (de)
HU (1) HU221730B1 (de)
IE (1) IE75892B1 (de)
IL (1) IL102168A (de)
MX (1) MX9202868A (de)
NO (1) NO303471B1 (de)
NZ (1) NZ243090A (de)
PH (1) PH30744A (de)
TW (1) TW304957B (de)
YU (1) YU63092A (de)
ZA (1) ZA924244B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4444260A1 (de) * 1994-12-13 1996-06-20 Hoechst Ag Cyclohexapeptide und deren Mischungen, Verfahren zur Herstellung sowie deren Verwendung
US6080719A (en) * 1996-02-23 2000-06-27 Hoechst Aktiengesellschaft Cyclohexapeptides and their mixtures, a process for preparing them, and their use
US6979728B2 (en) * 1998-05-04 2005-12-27 Baylor College Of Medicine Articles of manufacture and methods for array based analysis of biological molecules
IL125314A (en) 1998-07-12 2004-07-25 Peptor Ltd Processes for attaching amino acids using a bite - (trichloromethyl) carbonate
WO2000066155A1 (en) 1999-04-30 2000-11-09 La Jolla Institute For Allergy And Immunology Methods for preventing reactivation of latent virus and controlling virus replication
WO2000069898A2 (en) 1999-05-14 2000-11-23 Arbor Vita Corporation Molecular interactions in allergy cells
US20020073441A1 (en) 2000-12-13 2002-06-13 Ross Brian D. Compositions and methods for detecting proteolytic activity
US20050032060A1 (en) * 2001-08-31 2005-02-10 Shishir Shah Arrays comprising pre-labeled biological molecules and methods for making and using these arrays
US6916621B2 (en) * 2002-03-27 2005-07-12 Spectral Genomics, Inc. Methods for array-based comparitive binding assays
CN1695058B (zh) 2002-09-09 2011-04-13 生命树股份有限公司 诊断宫颈癌的方法
US7858322B2 (en) 2003-12-23 2010-12-28 Nono, Inc. Method of determining inhibition of binding to TRPM7 protein
ES2297688T3 (es) * 2004-03-12 2008-05-01 Intercell Ag Procedimiento para solubizar mezclas de peptidos.
US7572600B2 (en) * 2004-08-04 2009-08-11 Chemocentryx, Inc. Enzymatic activities in chemokine-mediated inflammation
JP2009507835A (ja) 2005-09-09 2009-02-26 ジョンズ ホプキンス ユニバーシティ 抗体、アゴニストおよびアンタゴニストを用いてニューリチン遺伝子をターゲティングすることによる調節性ｔ細胞およびｄｃの機能の操作
WO2011008768A1 (en) 2009-07-13 2011-01-20 Wayne State University Modified egfr ectodomain
CN115326937B (zh) * 2021-05-11 2024-06-18 山东省食品药品检验研究院 一种基因毒杂质捕捉用固相探针及其使用方法与应用
CN113678948A (zh) * 2021-08-31 2021-11-23 广州康瑞德饲料科技有限公司 一种饲料添加剂用自主组装小肽螯合铁的制备方法
CN113678947A (zh) * 2021-08-31 2021-11-23 广州康瑞德饲料科技有限公司 一种自主组装小肽螯合锰饲料添加剂及其制备方法
CN113796461A (zh) * 2021-09-18 2021-12-17 广州康瑞德饲料科技有限公司 一种自组装小肽螯合锌饲料添加剂及其制备方法
CN113841795A (zh) * 2021-09-18 2021-12-28 广州康瑞德饲料科技有限公司 一种自组装小肽螯合铜饲料添加剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272856C (de) *
DE260634C (de) *
WO1986000991A1 (en) * 1984-07-24 1986-02-13 Commonwealth Serum Laboratories Commission Method for determining mimotopes
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
NZ215865A (en) * 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
WO1986006487A1 (en) * 1985-04-22 1986-11-06 Commonwealth Serum Laboratories Commission Method for determining mimotopes
DE3631662A1 (de) * 1986-09-17 1988-03-24 Biotechnolog Forschung Gmbh Verfahren zur simultanen synthese mehrerer peptide an fester phase
JPS63190988A (ja) * 1987-02-02 1988-08-08 Hitachi Ltd 流量制御弁
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
DD272856A1 (de) * 1988-06-02 1989-10-25 Akad Wissenschaften Ddr Verfahren zur simultansynthese von peptiden
CA2009996A1 (en) * 1989-02-17 1990-08-17 Kathleen S. Cook Process for making genes encoding random polymers of amino acids
DE3935572A1 (de) * 1989-10-25 1991-05-02 Biotechnolog Forschung Gmbh Verfahren zur peptidsynthese und traeger dafuer
US5182366A (en) * 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
EP0558671B1 (de) * 1990-11-21 1999-01-27 Iterex Pharmaceuticals Ltd. Partnership Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen

Also Published As

Publication number Publication date
PH30744A (en) 1997-10-17
CN1069735A (zh) 1993-03-10
KR100237126B1 (ko) 2000-01-15
IL102168A0 (en) 1993-01-14
IE75892B1 (en) 1997-09-24
AU658636B2 (en) 1995-04-27
EP0519640A1 (de) 1992-12-23
EP0519640B1 (de) 1996-08-21
BR9202288A (pt) 1993-02-09
NZ243090A (en) 1993-11-25
FI922784A0 (fi) 1992-06-16
ZA924244B (en) 1993-12-10
AU1829792A (en) 1992-12-24
KR930000535A (ko) 1993-01-15
NO303471B1 (no) 1998-07-13
HU9201992D0 (en) 1992-09-28
TW304957B (de) 1997-05-11
NO922307D0 (no) 1992-06-12
IL102168A (en) 1998-12-06
ES2093199T3 (es) 1996-12-16
HU221730B1 (hu) 2002-12-28
US5422426A (en) 1995-06-06
FI922784A (fi) 1992-12-19
IE921960A1 (en) 1992-12-30
JPH05194586A (ja) 1993-08-03
HUT61572A (en) 1993-01-28
CZ287710B6 (cs) 2001-01-17
DK0519640T3 (da) 1996-09-09
YU63092A (sh) 1994-06-10
DE69212914T2 (de) 1997-02-13
ATE141611T1 (de) 1996-09-15
NO922307L (no) 1992-12-21
CZ178392A3 (en) 1993-01-13
MX9202868A (es) 1992-12-01
CA2071061A1 (en) 1992-12-19
CN1038034C (zh) 1998-04-15
GR3021295T3 (en) 1997-01-31

Similar Documents

Publication Publication Date Title
ATE141611T1 (de) Schnellsynthese und screening von peptidmimetika
WO2001012659A3 (en) Human dna sequences
DK150992A (da) Fremgangsmaade til fremstilling af et polypeptidfragment af faktor viii:c, dna-sekvens og ekstrachromosomalt element indeholdende en saadan dna-sekvens, som koder herfor
DE69434953D1 (de) Verfahren zur Herstellung einer cDNA Bank
DK2230299T3 (da) Hidtil ukendt cytokin ZCYTOR17-ligand
WO2004056865A3 (en) Method of modulation of interaction between receptor and ligand
EP0332104A3 (de) Chemisch regulierte Sequenzen und Gene, und ihre Verwendungen
DE60320362D1 (de) Verfahren zur Herstellung von Dipeptiden
DK0644202T3 (da) Syntetiske antigener til påvisning af antistoffer imod hepatitis C virus
ATE181320T1 (de) Verfahren zur herstellung von mischungen von n- acylierten aminosaeuren
WO2003016904A3 (en) Peptide sequence tags and method of using same
WO1998032858A3 (en) Mammalian chemokines; receptors; reagents; uses
DE69504795D1 (de) Methoden zur synthese und reinigung von peptiden
AUPP627498A0 (en) Novel peptides - i
WO1999009416A3 (en) Method of drug selection
EP0287997A3 (de) Des-19-leucine, 20-glutamin, 21-threonine calcitonin
DE60032453D1 (de) Ein verfahren zur synthese von ritonavir
EP0911408A3 (de) DNA kodierend für eine Serin/Threonin Kinase
DE3853092D1 (de) Verfahren zur Herstellung von Proteinen, die nicht in Proteinen vorkommende Aminosäuren enthalten.
EP1700866A3 (de) Transporter organischer Anionen des Gehirns und dessen Gen
ATE185373T1 (de) Herstellung und anwendung von polypeptiden, die durch bindmolekuele markiert sind
Sepetov et al. New approach in constructing and screening peptide libraries
ITRM930391A0 (it) Metodologia per la selezione di sequenze amminoacidiche, che interferiscono con il legame ligando-recettore, mediante librerie combinatoriali di peptidi sintetici sintetici multimerici.
TH4649EX (th) รีคอมบิแนนท์ อินฮิบิน

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee