DE69108138T2 - Imidazopyridinderivate und ihre Verwendung. - Google Patents

Imidazopyridinderivate und ihre Verwendung.

Info

Publication number
DE69108138T2
DE69108138T2 DE69108138T DE69108138T DE69108138T2 DE 69108138 T2 DE69108138 T2 DE 69108138T2 DE 69108138 T DE69108138 T DE 69108138T DE 69108138 T DE69108138 T DE 69108138T DE 69108138 T2 DE69108138 T2 DE 69108138T2
Authority
DE
Germany
Prior art keywords
imidazopyridine derivatives
chem
compound
formula
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69108138T
Other languages
English (en)
Other versions
DE69108138D1 (de
Inventor
Muneo Takatani
Yoshio Kozai
Kiminori Tomimatsu
Yumiko Shibouta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69108138D1 publication Critical patent/DE69108138D1/de
Application granted granted Critical
Publication of DE69108138T2 publication Critical patent/DE69108138T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
DE69108138T 1990-07-30 1991-07-30 Imidazopyridinderivate und ihre Verwendung. Expired - Fee Related DE69108138T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20296490 1990-07-30
JP20296390 1990-07-30
JP12127791 1991-05-27
JP14018691 1991-06-12

Publications (2)

Publication Number Publication Date
DE69108138D1 DE69108138D1 (de) 1995-04-20
DE69108138T2 true DE69108138T2 (de) 1995-07-06

Family

ID=27470767

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69108138T Expired - Fee Related DE69108138T2 (de) 1990-07-30 1991-07-30 Imidazopyridinderivate und ihre Verwendung.

Country Status (7)

Country Link
US (3) US5244908A (de)
EP (1) EP0471236B1 (de)
AT (1) ATE119774T1 (de)
CA (1) CA2048110C (de)
DE (1) DE69108138T2 (de)
DK (1) DK0471236T3 (de)
ES (1) ES2069137T3 (de)

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
US5350758A (en) * 1992-07-08 1994-09-27 Merrell Dow Pharmaceuticals Inc. Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis
JP3545461B2 (ja) * 1993-09-10 2004-07-21 エーザイ株式会社 二環式ヘテロ環含有スルホンアミド誘導体
US5698518A (en) * 1994-03-30 1997-12-16 Oklahoma Medical Research Foundation Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists
AU2682695A (en) * 1994-06-20 1996-01-15 Takeda Chemical Industries Ltd. Condensed imidazole compounds, their production and use
AU721034B2 (en) 1996-02-15 2000-06-22 Biosense, Inc. Catheter based surgery
KR19990087814A (ko) * 1996-04-24 1999-12-27 다케다 야쿠힌 고교 가부시키가이샤 과지방혈증 방지제로서의 융합 이미다조피리딘유도체
DE19624659A1 (de) 1996-06-20 1998-01-08 Klinge Co Chem Pharm Fab Neue Pyridylalken- und Pyridylalkinsäureamide
DE19624704A1 (de) * 1996-06-20 1998-01-08 Klinge Co Chem Pharm Fab Neue Pyridylalkansäureamide
US6451816B1 (en) 1997-06-20 2002-09-17 Klinge Pharma Gmbh Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression
US6443974B1 (en) 1996-07-28 2002-09-03 Biosense, Inc. Electromagnetic cardiac biostimulation
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.
DE19756235A1 (de) 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
US6903118B1 (en) 1997-12-17 2005-06-07 Klinge Pharma Gmbh Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides
DE19756212A1 (de) 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide
DE19756261A1 (de) * 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide
US20030113303A1 (en) * 1998-02-05 2003-06-19 Yitzhack Schwartz Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances
US20030129750A1 (en) * 1998-02-05 2003-07-10 Yitzhack Schwartz Homing of donor cells to a target zone in tissue using active therapeutics or substances
ES2255155T3 (es) 1998-02-05 2006-06-16 Biosense Webster, Inc. Dispositivo para la administracion intracardiaca de farmacos.
EP1031564A1 (de) 1999-02-26 2000-08-30 Klinge Pharma GmbH Hemmer der Nicotinamidmonononukleotide-Bildung und deren Verwendung zur Krebstherapie
EP1076091A1 (de) * 1999-08-09 2001-02-14 Universite Catholique De Louvain Arzneimittel für die Verhinderung und/oder Behandlung von Herzischämie, peripheren Gefässkrankheiten, Tumoren und Wunden
US6911476B2 (en) 2000-03-13 2005-06-28 Eli Lilly And Company Sulfonamide derivatives
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
AU2005264998A1 (en) 2004-06-17 2006-01-26 Wyeth The present invention relates to methods of making Gonadotropin Releasing Hormone ('GnRH') (also known as Leutinizing Hormone Releasing Hormone) receptor antagonists
US7696210B2 (en) 2004-06-17 2010-04-13 Wyeth Gonadotropin releasing hormone receptor antagonists
US7582634B2 (en) 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7534796B2 (en) 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7531542B2 (en) 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
RU2764243C2 (ru) 2017-09-22 2022-01-14 ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи Гетероциклические соединения в качестве ингибиторов PAD
HUE061607T2 (hu) 2017-10-18 2023-07-28 Jubilant Epipad LLC Imidazopiridin vegyületek mint PAD inhibitorok
CA3080677A1 (en) 2017-11-06 2019-05-09 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation
EP3704120B1 (de) 2017-11-24 2024-03-06 Jubilant Episcribe LLC Heterozyklische verbindungen als prmt5 inhibitoren
AU2019234185A1 (en) 2018-03-13 2020-10-01 Jubilant Prodel LLC. Bicyclic compounds as inhibitors of PD1/PD-L1 interaction/activation

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3509167A (en) * 1967-09-18 1970-04-28 Pfizer & Co C Certain 3-nitroimidazo-(1,2-a)pyridines
US4096264A (en) * 1975-12-09 1978-06-20 Merck & Co., Inc. Certain substituted imidazo [1,2-a] pyridines
US4177274A (en) * 1975-12-09 1979-12-04 Merck & Co., Inc. Substituted imidazo [1,2-a] pyridines
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
US4409226A (en) * 1981-10-05 1983-10-11 Schering Corporation Imidazo[1,5-a]pyridines
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3689762T2 (de) * 1985-12-13 1994-08-18 Takeda Chemical Industries Ltd Antibakterielle Verbindungen, ihre Herstellung und Verwendung.
JPS6310792A (ja) * 1986-03-10 1988-01-18 Takeda Chem Ind Ltd 新規セフエム化合物
JP2519054B2 (ja) * 1986-06-09 1996-07-31 武田薬品工業株式会社 新規セフェム化合物
US4833149A (en) * 1986-09-22 1989-05-23 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
EP0471236A1 (de) 1992-02-19
US5244908A (en) 1993-09-14
US5395839A (en) 1995-03-07
CA2048110A1 (en) 1992-01-31
CA2048110C (en) 2002-06-25
EP0471236B1 (de) 1995-03-15
ATE119774T1 (de) 1995-04-15
DE69108138D1 (de) 1995-04-20
ES2069137T3 (es) 1995-05-01
DK0471236T3 (da) 1995-07-24
US5587383A (en) 1996-12-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee