DE69022368T2 - Quinolin-3-carboxanilid-derivate. - Google Patents

Quinolin-3-carboxanilid-derivate.

Info

Publication number
DE69022368T2
DE69022368T2 DE69022368T DE69022368T DE69022368T2 DE 69022368 T2 DE69022368 T2 DE 69022368T2 DE 69022368 T DE69022368 T DE 69022368T DE 69022368 T DE69022368 T DE 69022368T DE 69022368 T2 DE69022368 T2 DE 69022368T2
Authority
DE
Germany
Prior art keywords
group
quinolin
methoxy
hydroxy
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022368T
Other languages
English (en)
Other versions
DE69022368D1 (de
Inventor
Per Gunnarsson
Torbjoern Stalhandske
Kerstin Strandgarden
Karl-Erik Lundvall
Kaj Johansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of DE69022368D1 publication Critical patent/DE69022368D1/de
Application granted granted Critical
Publication of DE69022368T2 publication Critical patent/DE69022368T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69022368T 1989-06-09 1990-05-31 Quinolin-3-carboxanilid-derivate. Expired - Fee Related DE69022368T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902076A SE8902076D0 (sv) 1989-06-09 1989-06-09 Derivatives of quinoline-3-carboxanilide
PCT/SE1990/000375 WO1990015052A1 (en) 1989-06-09 1990-05-31 Derivatives of quinoline-3-carboxanilide

Publications (2)

Publication Number Publication Date
DE69022368D1 DE69022368D1 (de) 1995-10-19
DE69022368T2 true DE69022368T2 (de) 1996-05-02

Family

ID=20376220

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022368T Expired - Fee Related DE69022368T2 (de) 1989-06-09 1990-05-31 Quinolin-3-carboxanilid-derivate.

Country Status (11)

Country Link
EP (1) EP0429627B1 (de)
JP (1) JPH04500373A (de)
AT (1) ATE127791T1 (de)
AU (1) AU648026B2 (de)
CA (1) CA2033211A1 (de)
DE (1) DE69022368T2 (de)
DK (1) DK0429627T3 (de)
ES (1) ES2077071T3 (de)
NZ (1) NZ233860A (de)
SE (1) SE8902076D0 (de)
WO (1) WO1990015052A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310913A (en) * 1989-06-09 1994-05-10 Kabi Pharmacia Aktiebolag Derivatives of quinoline-3-carboxanilide
US5268378A (en) * 1990-05-31 1993-12-07 Merck Sharp & Dohme, Limited Dioxo-tetrahydroquinoline derivatives
GB9108547D0 (en) * 1991-04-22 1991-06-05 Fujisawa Pharmaceutical Co Quinoline derivatives
DE4138820A1 (de) * 1991-11-26 1993-05-27 Basf Ag Chinolin-3-carbonsaeureamide, deren herstellung und verwendung
GB9311562D0 (en) * 1993-06-04 1993-07-21 Fujisawa Pharmaceutical Co Heterocyclic derivatives
GB9404378D0 (en) * 1994-03-07 1994-04-20 Fujisawa Pharmaceutical Co Quinoline derivatives
SE9400810D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of Quinoline-3-carboxamide compounds
SE9400809D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of quinoline-3-carboxamide compounds
WO1997048694A1 (en) * 1996-06-20 1997-12-24 Board Of Regents, The University Of Texas System Compounds and methods for providing pharmacologically active preparations and uses thereof
JP2000256323A (ja) 1999-01-08 2000-09-19 Japan Tobacco Inc ２−オキソキノリン化合物及びその医薬用途
US8314124B2 (en) 2004-02-06 2012-11-20 Active Biotech Ab Crystalline salts of quinoline compounds and methods for preparing them
SE0400235D0 (sv) 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
CN103333107A (zh) 2005-10-19 2013-10-02 泰华制药工业有限公司 拉奎尼莫钠晶体及其制备方法
BRPI0713694A2 (pt) 2006-06-12 2012-10-30 Teva Pharma composição farmacêutica, processo para preparar composição farmacêutica, embalagens vedada, métodos para tratar um indivìduo afligido com uma forma de esclerose múltipla, e para aliviar um sintoma de esclerose múltipla em um indivìduo afligido com uma forma de esclerose múltipla, e, uso da composição farmacêutica
EP2682120B1 (de) 2007-12-20 2016-08-03 Teva Pharmaceutical Industries, Ltd. Stabile Laquinimod-Präparate
NZ591315A (en) 2008-09-03 2012-08-31 Teva Pharma 2-oxo-1,2-dihydro-quinoline modulators of immune function
MX2014009889A (es) 2012-02-16 2014-11-13 Teva Pharma N-etil-n-fenil-1,2-dihidro-4,5-di-hidroxi-1-metil-2-oxo-3-quinoli ncarboxamida, preparacion y usos de los mismos.
TW201350467A (zh) 2012-05-08 2013-12-16 Teva Pharma Ｎ－乙基－４－羥基－１－甲基－５－（甲基（２，３，４，５，６－五羥基己基）胺基）－２－側氧－ｎ－苯基－１，２－二氫喹啉－３－甲醯胺
US8975279B2 (en) 2012-11-07 2015-03-10 Teva Pharmaceutical Industries, Ltd. Amine salts of laquinimod
KR20150143499A (ko) 2013-03-14 2015-12-23 테바 파마슈티컬 인더스트리즈 리미티드 라퀴니모드 나트륨의 결정 및 이의 개선된 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
DE3420116A1 (de) * 1984-05-30 1985-12-05 Bayer Ag, 5090 Leverkusen Immunstimulierende mittel
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe

Also Published As

Publication number Publication date
ES2077071T3 (es) 1995-11-16
ATE127791T1 (de) 1995-09-15
NZ233860A (en) 1991-04-26
CA2033211A1 (en) 1990-12-10
AU648026B2 (en) 1994-04-14
SE8902076D0 (sv) 1989-06-09
EP0429627A1 (de) 1991-06-05
DK0429627T3 (da) 1995-11-20
WO1990015052A1 (en) 1990-12-13
AU5923490A (en) 1991-01-07
EP0429627B1 (de) 1995-09-13
DE69022368D1 (de) 1995-10-19
JPH04500373A (ja) 1992-01-23

Similar Documents

Publication Publication Date Title
DE69022368D1 (de) Quinolin-3-carboxanilid-derivate.
DE69108138D1 (de) Imidazopyridinderivate und ihre Verwendung.
NO931695L (no) Nye 4-arylpiperaciner og 4-arylpiperidiner
ES2181730T3 (es) Piridilpirazoles substituidos.
FI925415A (fi) Framstaellning av substituerade piperidiner
CA2037975A1 (en) 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
FI930092A0 (fi) Indanopyrrolidinkarbamater
KR960702307A (ko) 항불안약 (anxiolytic agent)
FI904033A0 (fi) Nya 1,3-oxaziner.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee