DE69102462T2 - Verfahren zur Herstellung von 1,5-Benzothiazepin-Derivaten. - Google Patents

Verfahren zur Herstellung von 1,5-Benzothiazepin-Derivaten.

Info

Publication number
DE69102462T2
DE69102462T2 DE69102462T DE69102462T DE69102462T2 DE 69102462 T2 DE69102462 T2 DE 69102462T2 DE 69102462 T DE69102462 T DE 69102462T DE 69102462 T DE69102462 T DE 69102462T DE 69102462 T2 DE69102462 T2 DE 69102462T2
Authority
DE
Germany
Prior art keywords
formula
preparation
chem
salt
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69102462T
Other languages
English (en)
Other versions
DE69102462D1 (de
Inventor
Tadayuki Koumoto
Hironori Hayashi
Toshiya Kadowaki
Masahiko Seto
Toyonari Oine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE69102462D1 publication Critical patent/DE69102462D1/de
Publication of DE69102462T2 publication Critical patent/DE69102462T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE69102462T 1990-03-08 1991-03-08 Verfahren zur Herstellung von 1,5-Benzothiazepin-Derivaten. Expired - Fee Related DE69102462T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5779890 1990-03-08

Publications (2)

Publication Number Publication Date
DE69102462D1 DE69102462D1 (de) 1994-07-21
DE69102462T2 true DE69102462T2 (de) 1994-10-06

Family

ID=13065923

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69102462T Expired - Fee Related DE69102462T2 (de) 1990-03-08 1991-03-08 Verfahren zur Herstellung von 1,5-Benzothiazepin-Derivaten.

Country Status (17)

Country Link
US (1) US5294706A (de)
EP (1) EP0447135B1 (de)
JP (1) JPH085869B2 (de)
KR (1) KR970002879B1 (de)
CN (1) CN1029847C (de)
AT (1) ATE107295T1 (de)
AU (1) AU632218B2 (de)
CA (1) CA2037298C (de)
DE (1) DE69102462T2 (de)
DK (1) DK0447135T3 (de)
ES (1) ES2057757T3 (de)
FI (1) FI93011C (de)
FR (1) FR2659328B1 (de)
HK (1) HK1000126A1 (de)
HU (1) HU210146B (de)
IE (1) IE65974B1 (de)
IL (1) IL97404A0 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
ES2069003T3 (es) * 1989-04-28 1995-05-01 Tanabe Seiyaku Co Procedimiento para preparar derivados de 1,5-benzotiazepina.
US4983733A (en) * 1989-11-20 1991-01-08 Marion Laboratories, Inc. Process for preparing 2-aromatic-3-halobenzothiazepines
IT1240686B (it) * 1990-04-27 1993-12-17 Luso Farmaco Inst Derivati 1,5-benzotiazepinonici, loro preparazione e uso farmaceutico
IL100157A (en) * 1990-11-29 1995-12-08 Tanabe Seiyaku Co Preparation of a result of 1,5-benzothiazepine
IT1249318B (it) * 1991-05-23 1995-02-22 Zambon Spa Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
SG50796A1 (en) * 1996-02-23 1998-07-20 Tanabe Seiyaku Co Process for preparing 1,5-benzothiazepine derivative
NL1002687C2 (nl) * 1996-03-22 1997-09-23 Dsm Nv Werkwijze voor de bereiding van een benzothiazepine.
IL123352A0 (en) 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
CN112279820B (zh) * 2020-12-18 2021-04-02 苏州开元民生科技股份有限公司 2-(4-甲氧苯基)-3-羟基-2,3-二氢-1,5-苯并硫氮杂卓酮的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
FR2360124A1 (fr) * 1976-07-30 1978-02-24 Amiens Const Electro Mecan Procede de controle de commutation de la puissance de chauffage dans un appareil electrodomestique a programmateur et dispositif pour la mise en oeuvre dudit procede
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
EP0098422B1 (de) * 1982-07-07 1987-12-09 Siegfried Aktiengesellschaft Verfahren zur Herstellung von 4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazin-3-carboxamid 1,1-dioxid
ZA893392B (en) * 1988-05-24 1990-01-31 Hoffmann La Roche Process for the manufacture of optically active naphthothiazepinones
US5008411A (en) * 1988-05-24 1991-04-16 Hoffmann-La Roche Inc. Glycidic acid ester and process of preparation
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
ES2069003T3 (es) * 1989-04-28 1995-05-01 Tanabe Seiyaku Co Procedimiento para preparar derivados de 1,5-benzotiazepina.
US5055575A (en) * 1990-04-12 1991-10-08 Tanabe Seiyaku Co., Ltd. Process for preparing 1,5-benzothiazepine derivatives

Also Published As

Publication number Publication date
ES2057757T3 (es) 1994-10-16
FR2659328B1 (fr) 1994-11-04
CA2037298C (en) 1998-08-18
FI93011B (fi) 1994-10-31
AU632218B2 (en) 1992-12-17
JPH04234866A (ja) 1992-08-24
CN1029847C (zh) 1995-09-27
US5294706A (en) 1994-03-15
CN1054597A (zh) 1991-09-18
JPH085869B2 (ja) 1996-01-24
EP0447135B1 (de) 1994-06-15
FI911080A0 (fi) 1991-03-04
KR910016727A (ko) 1991-11-05
HK1000126A1 (en) 1997-12-12
IL97404A0 (en) 1992-06-21
DE69102462D1 (de) 1994-07-21
HU210146B (en) 1995-02-28
FI93011C (fi) 1995-02-10
HU910742D0 (en) 1991-09-30
DK0447135T3 (da) 1994-07-11
EP0447135A1 (de) 1991-09-18
FR2659328A1 (fr) 1991-09-13
AU7199391A (en) 1991-09-12
IE910755A1 (en) 1991-09-11
ATE107295T1 (de) 1994-07-15
HUT65340A (en) 1994-05-02
KR970002879B1 (ko) 1997-03-12
FI911080A (fi) 1991-09-09
IE65974B1 (en) 1995-11-29
CA2037298A1 (en) 1991-09-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee