DE3788369T2 - Verfahren zur Herstellung von Cephalosporinderivaten. - Google Patents

Verfahren zur Herstellung von Cephalosporinderivaten.

Info

Publication number
DE3788369T2
DE3788369T2 DE87304208T DE3788369T DE3788369T2 DE 3788369 T2 DE3788369 T2 DE 3788369T2 DE 87304208 T DE87304208 T DE 87304208T DE 3788369 T DE3788369 T DE 3788369T DE 3788369 T2 DE3788369 T2 DE 3788369T2
Authority
DE
Germany
Prior art keywords
formula
group
chem
compound
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87304208T
Other languages
English (en)
Other versions
DE3788369D1 (de
Inventor
Frank Loftus
Stephen John Pegg
Evan William Snape
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE3788369D1 publication Critical patent/DE3788369D1/de
Application granted granted Critical
Publication of DE3788369T2 publication Critical patent/DE3788369T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE87304208T 1986-05-15 1987-05-12 Verfahren zur Herstellung von Cephalosporinderivaten. Expired - Fee Related DE3788369T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868611823A GB8611823D0 (en) 1986-05-15 1986-05-15 Process

Publications (2)

Publication Number Publication Date
DE3788369D1 DE3788369D1 (de) 1994-01-20
DE3788369T2 true DE3788369T2 (de) 1994-04-21

Family

ID=10597897

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87304208T Expired - Fee Related DE3788369T2 (de) 1986-05-15 1987-05-12 Verfahren zur Herstellung von Cephalosporinderivaten.

Country Status (17)

Country Link
US (1) US4939250A (de)
EP (1) EP0246068B1 (de)
JP (1) JPH089628B2 (de)
KR (1) KR950010083B1 (de)
AT (1) ATE98248T1 (de)
AU (1) AU606337B2 (de)
CA (1) CA1291118C (de)
DE (1) DE3788369T2 (de)
DK (1) DK248287A (de)
ES (1) ES2061494T3 (de)
FI (1) FI872135A (de)
GB (2) GB8611823D0 (de)
HU (1) HU202539B (de)
NO (1) NO872006L (de)
NZ (1) NZ220308A (de)
PT (1) PT84870B (de)
ZA (1) ZA873095B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
KR100392409B1 (ko) * 2000-03-20 2003-07-22 한미정밀화학주식회사 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI793566A (fi) * 1978-11-15 1980-05-16 Glaxo Group Ltd Kefalosporinantibioter
JPS58167595A (ja) * 1982-03-15 1983-10-03 グラクソ・グル−プ・リミテツド セフアロスポリン化合物
GR78718B (de) * 1983-01-31 1984-09-27 Ici Pharma
US4702544A (en) * 1983-05-06 1987-10-27 Magnetic Controls Company Electrical connector
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
EP0187456A1 (de) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporinverbindungen
IL77458A (en) * 1985-01-14 1990-07-26 Eisai Co Ltd Cephem derivatives,their production and antibacterial compositions containing them and certain novel intermediates therefor

Also Published As

Publication number Publication date
DK248287D0 (da) 1987-05-14
NO872006D0 (no) 1987-05-14
CA1291118C (en) 1991-10-22
US4939250A (en) 1990-07-03
NZ220308A (en) 1989-01-06
DE3788369D1 (de) 1994-01-20
HU202539B (en) 1991-03-28
AU606337B2 (en) 1991-02-07
HUT43855A (en) 1987-12-28
EP0246068B1 (de) 1993-12-08
ES2061494T3 (es) 1994-12-16
JPH089628B2 (ja) 1996-01-31
ZA873095B (en) 1988-02-24
ATE98248T1 (de) 1993-12-15
EP0246068A3 (en) 1989-06-14
DK248287A (da) 1987-11-16
FI872135A0 (fi) 1987-05-14
KR950010083B1 (ko) 1995-09-06
JPS62273985A (ja) 1987-11-28
PT84870A (pt) 1988-05-27
AU7254187A (en) 1987-11-19
FI872135A (fi) 1987-11-16
EP0246068A2 (de) 1987-11-19
PT84870B (pt) 1994-09-30
KR870011143A (ko) 1987-12-21
GB8611823D0 (en) 1986-06-25
GB8709596D0 (en) 1987-05-28
NO872006L (no) 1987-11-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee