DE69015682D1 - Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten. - Google Patents

Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten.

Info

Publication number
DE69015682D1
DE69015682D1 DE69015682T DE69015682T DE69015682D1 DE 69015682 D1 DE69015682 D1 DE 69015682D1 DE 69015682 T DE69015682 T DE 69015682T DE 69015682 T DE69015682 T DE 69015682T DE 69015682 D1 DE69015682 D1 DE 69015682D1
Authority
DE
Germany
Prior art keywords
formula
lower alkyl
alkyl group
chem
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69015682T
Other languages
English (en)
Other versions
DE69015682T2 (de
Inventor
Shigeru Nishimoto
Akio Nakao
Yasuji Ikeda
Hiroyuki Nate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1109794A external-priority patent/JPH0699409B2/ja
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE69015682D1 publication Critical patent/DE69015682D1/de
Publication of DE69015682T2 publication Critical patent/DE69015682T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69015682T 1989-04-28 1990-04-10 Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten. Expired - Fee Related DE69015682T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1109794A JPH0699409B2 (ja) 1989-04-28 1989-04-28 １，５―ベンゾチアゼピン誘導体の製法

Publications (2)

Publication Number Publication Date
DE69015682D1 true DE69015682D1 (de) 1995-02-16
DE69015682T2 DE69015682T2 (de) 1995-05-11

Family

ID=14519390

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69015682T Expired - Fee Related DE69015682T2 (de) 1989-04-28 1990-04-10 Verfahren zur Herstellung von 1,5-Benzothiazepinderivaten.

Country Status (15)

Country Link
EP (2) EP0612737A1 (de)
KR (1) KR970002465B1 (de)
CN (2) CN1030389C (de)
AT (1) ATE116643T1 (de)
AU (1) AU616352B2 (de)
CA (1) CA2015179C (de)
DE (1) DE69015682T2 (de)
DK (1) DK0395302T3 (de)
ES (1) ES2069003T3 (de)
FI (1) FI94245C (de)
FR (1) FR2646423A1 (de)
HK (1) HK214996A (de)
HU (1) HU203883B (de)
IE (2) IE940709L (de)
IL (1) IL94209A0 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
IT1234387B (it) * 1989-07-12 1992-05-18 Zambon Spa Processo di purificazione di intermedi utili nella preparazione del diltiazem
ZA906810B (en) * 1989-08-31 1991-10-30 Marion Merrell Dow Inc Heterogeneous synthesis of azepinones from esters
US4983733A (en) * 1989-11-20 1991-01-08 Marion Laboratories, Inc. Process for preparing 2-aromatic-3-halobenzothiazepines
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
IT1240686B (it) * 1990-04-27 1993-12-17 Luso Farmaco Inst Derivati 1,5-benzotiazepinonici, loro preparazione e uso farmaceutico
IT1249318B (it) * 1991-05-23 1995-02-22 Zambon Spa Processo per la preparazione di benzotiazepine per ciclizzazione con acidi fosfonici
GB9423172D0 (en) * 1994-11-17 1995-01-04 Wellcom Foundation The Limited Hypolipidemic benzothiazepines
NL1002687C2 (nl) * 1996-03-22 1997-09-23 Dsm Nv Werkwijze voor de bereiding van een benzothiazepine.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE31309T1 (de) * 1982-07-07 1987-12-15 Siegfried Ag Verfahren zur herstellung von 4-hydroxy-2-methyln-2-pyridyl-2h-1,2-benzothiazin-3-carboxamid 1,1- dioxid.
US4552695A (en) * 1983-04-21 1985-11-12 Shionogi & Co., Ltd. Process for production of diltiazem hydrochloride
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
ZA893392B (en) * 1988-05-24 1990-01-31 Hoffmann La Roche Process for the manufacture of optically active naphthothiazepinones
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
JPH0798813B2 (ja) * 1989-04-28 1995-10-25 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体の製法
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法

Also Published As

Publication number Publication date
FI902031A0 (fi) 1990-04-23
HUT55374A (en) 1991-05-28
DK0395302T3 (da) 1995-03-20
HU902608D0 (en) 1990-09-28
FI94245B (fi) 1995-04-28
EP0395302A1 (de) 1990-10-31
DE69015682T2 (de) 1995-05-11
ES2069003T3 (es) 1995-05-01
FR2646423A1 (fr) 1990-11-02
FR2646423B1 (de) 1994-11-10
AU616352B2 (en) 1991-10-24
KR970002465B1 (ko) 1997-03-05
EP0612737A1 (de) 1994-08-31
IE66470B1 (en) 1995-12-27
CN1046902A (zh) 1990-11-14
KR900016170A (ko) 1990-11-12
EP0395302B1 (de) 1995-01-04
CA2015179A1 (en) 1990-10-28
ATE116643T1 (de) 1995-01-15
CN1030389C (zh) 1995-11-29
CA2015179C (en) 1996-12-10
HU203883B (en) 1991-10-28
CN1128760A (zh) 1996-08-14
IE901510L (en) 1990-10-28
HK214996A (en) 1996-12-13
IE940709L (en) 1990-10-28
AU5385890A (en) 1990-11-01
FI94245C (fi) 1995-08-10
IL94209A0 (en) 1991-01-31

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER ANMELDETAG IST ZU AENDERN IN: 20.04.90

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee