DE69019962D1 - Glykoprotein menschlichen ursprungs, physiologisch aktiver faktor, der es enthält und heilmittel daraus. - Google Patents

Glykoprotein menschlichen ursprungs, physiologisch aktiver faktor, der es enthält und heilmittel daraus.

Info

Publication number
DE69019962D1
DE69019962D1 DE69019962T DE69019962T DE69019962D1 DE 69019962 D1 DE69019962 D1 DE 69019962D1 DE 69019962 T DE69019962 T DE 69019962T DE 69019962 T DE69019962 T DE 69019962T DE 69019962 D1 DE69019962 D1 DE 69019962D1
Authority
DE
Germany
Prior art keywords
human origin
physiologically active
healing agents
active factor
glycoprotein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69019962T
Other languages
English (en)
Other versions
DE69019962T2 (de
Inventor
Kanji Higashio
Shinjiro Mitsuda
Nobuyuki Shima
Yasuharu Itagaki
Masaya Nagao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Atlas Pharmaceuticals Inc Sunnyvale Calif Us
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26340889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69019962(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Application granted granted Critical
Publication of DE69019962D1 publication Critical patent/DE69019962D1/de
Publication of DE69019962T2 publication Critical patent/DE69019962T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
DE69019962T 1989-03-10 1990-03-09 Glykoprotein menschlichen ursprungs, physiologisch aktiver faktor, der es enthält und heilmittel daraus. Expired - Lifetime DE69019962T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5863189 1989-03-10
JP669290 1990-01-16
PCT/JP1990/000314 WO1990010651A1 (fr) 1989-03-10 1990-03-09 Glycoproteine humaine, facteur physiologiquement actif la contenant, et preparation pharmaceutique le contenant en tant qu'ingredient actif

Publications (2)

Publication Number Publication Date
DE69019962D1 true DE69019962D1 (de) 1995-07-13
DE69019962T2 DE69019962T2 (de) 1995-11-23

Family

ID=26340889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69019962T Expired - Lifetime DE69019962T2 (de) 1989-03-10 1990-03-09 Glykoprotein menschlichen ursprungs, physiologisch aktiver faktor, der es enthält und heilmittel daraus.

Country Status (17)

Country Link
US (2) US5587359A (de)
EP (1) EP0462277B1 (de)
JP (1) JPH0768272B1 (de)
KR (1) KR960009054B1 (de)
AT (1) ATE123498T1 (de)
AU (1) AU629314B2 (de)
CA (1) CA2049017C (de)
DE (1) DE69019962T2 (de)
DK (1) DK0462277T3 (de)
ES (1) ES2075199T3 (de)
FI (1) FI102681B1 (de)
HU (2) HU212513B (de)
IE (1) IE64005B1 (de)
NO (1) NO180796C (de)
NZ (1) NZ232813A (de)
RU (1) RU2113480C1 (de)
WO (1) WO1990010651A1 (de)

Families Citing this family (37)

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US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
EP0461560B1 (de) * 1990-06-11 1998-11-18 Toshikazu Nakamura Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
WO1992001053A1 (fr) * 1990-07-13 1992-01-23 Snow Brand Milk Products Co., Ltd. Plasmide contenant l'adn qui code pour la sequence d'acides amines du facteur tcf-ii, cellules transformees par ce plasmide et production d'une substance physiologiquement active grace a l'utilisation de ce plasmide
US5821223A (en) * 1990-09-14 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Method of stimulating cell growth with a novel broad spectrum human lung fibroblast-derived mitogen
EP0571387B1 (de) * 1990-09-14 2003-12-17 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Ein nicht-mitogener kompetitiver hgf-antagonist
JP3200609B2 (ja) * 1990-12-28 2001-08-20 敏一 中村 上皮細胞増殖促進剤
JPH0597A (ja) * 1991-06-21 1993-01-08 Snow Brand Milk Prod Co Ltd 新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法
KR100271087B1 (en) * 1992-07-16 2000-11-01 Snow Brand Milk Products Co Ltd Protein synthesis stimulator comprising tcf-2 for the treatment of hypoproteinemia
KR100260964B1 (ko) * 1992-07-16 2000-07-01 쇼노 카츄야 Tcf-ii를 유효성분으로 하는 혈액응고 정상화제
US5648233A (en) * 1992-12-28 1997-07-15 Snow Brand Milk Products Co., Ltd. Modified tumor cytotoxic factor (TCF) and DNA encoding such
JP3552240B2 (ja) * 1993-02-23 2004-08-11 第一製薬株式会社 高濃度ｔｃｆ製剤
US5837676A (en) * 1993-10-18 1998-11-17 Long Island Jewish Medical Center Use of scatter factor to enhance angiogenesis
JP2747979B2 (ja) * 1994-08-19 1998-05-06 雪印乳業株式会社 ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬
ES2206523T3 (es) * 1994-12-27 2004-05-16 Daiichi Pharmaceutical Co., Ltd. Mutantes de tecf.
NZ298141A (en) * 1994-12-27 2000-12-22 Snow Brand Milk Products Co Ltd Treating lipid metabolism disorder using TCF-II
AU4027601A (en) * 1995-07-11 2001-07-26 Snow Brand Milk Products Co., Ltd. Lyophilized HGF preparations
JP3927248B2 (ja) * 1995-07-11 2007-06-06 第一製薬株式会社 Ｈｇｆ凍結乾燥製剤
JP4006058B2 (ja) 1997-03-11 2007-11-14 第一三共株式会社 多臓器不全予防及び／又は治療剤
ZA982068B (en) * 1997-03-14 1998-09-16 Snow Brand Milk Products Co Ltd Agent for preventing and/or treating cachexia
JPH1129493A (ja) * 1997-07-14 1999-02-02 Snow Brand Milk Prod Co Ltd 放射線障害予防及び／又は治療剤
JPH11269091A (ja) * 1998-03-19 1999-10-05 Snow Brand Milk Prod Co Ltd 敗血症予防及び／又は治療剤
CN1352087A (zh) * 2000-11-02 2002-06-05 上海博德基因开发有限公司 一种新的多肽——人糖蛋白42和编码这种多肽的多核苷酸
KR100562824B1 (ko) 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US8034831B2 (en) 2002-11-06 2011-10-11 Celgene Corporation Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
US7563810B2 (en) 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
CN100417412C (zh) * 2003-03-28 2008-09-10 威海赛洛金药业有限公司 促肝细胞生长素注射液及制备方法和应用
JP4728807B2 (ja) * 2003-09-03 2011-07-20 敏一 中村 ヒト組換えｈｇｆを含有する皮膚潰瘍予防治癒剤
RU2520817C2 (ru) * 2006-01-25 2014-06-27 Октафарма Аг Очистка и применение фактора, способствующего заживлению ран
US20100124782A1 (en) * 2007-04-28 2010-05-20 Applied Cell Biotechnologies, Inc. Composition For Repairing Defect In Skin Or Gingival Soft Tissue And Method Of Culturing Autologous Fibroblasts
US20090202606A1 (en) * 2008-01-25 2009-08-13 Viromed Co., Ltd. Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor
CN102046792B (zh) * 2008-04-09 2014-12-10 百疗医株式会社 用于提高质粒dna表达的冻干dna制剂
CN105682676B (zh) 2013-10-22 2020-10-23 赫利世弥斯株式会社 利用肝细胞生长因子的两种以上的异构体的肌萎缩性侧索硬化症预防或治疗用组合物
LT3138575T (lt) 2014-04-28 2021-08-25 Eisai R&D Management Co., Ltd. Liofilizuoto hgf paruošimas
DK3192524T3 (da) 2014-09-10 2022-02-14 Kringle Pharma Inc Hgf præparat egnet til behandling af neurologiske lidelser
US11548926B2 (en) 2016-03-17 2023-01-10 Eisai R&D Management Co., Ltd. Method for producing an active hepatocyte growth factor (HGF)
EP3823677A4 (de) 2018-07-19 2022-06-01 Helixmith Co., Ltd. Lyophilisierte pharmazeutische zusammensetzungen für nackte dna-gentherapie
CA3218000A1 (en) 2021-05-14 2022-11-17 Claris Biotherapeutics, Inc. Compositions of growth factor for the treatment of eye disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58148826A (ja) * 1982-02-26 1983-09-05 Mochida Pharmaceut Co Ltd 糖蛋白質および腫瘍治療剤
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
DE3643182A1 (de) * 1986-12-18 1988-06-30 Behringwerke Ag Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4
JPS6410998A (en) * 1986-12-22 1989-01-13 Green Cross Corp Tumor cell inhibitory factor
JPS63243032A (ja) * 1987-03-27 1988-10-07 Green Cross Corp:The トロンビンの加熱処理方法
DE3729863A1 (de) * 1987-09-05 1989-03-16 Boehringer Mannheim Gmbh Stabilisierte erythropoietin-lyophilisate
JPH0741891B2 (ja) * 1987-08-26 1995-05-10 凸版印刷株式会社 容器素材成形装置
FI80741C (fi) * 1987-10-29 1990-07-10 Laennen Tehtaat Oy Modifierat papper.
WO1992001053A1 (fr) * 1990-07-13 1992-01-23 Snow Brand Milk Products Co., Ltd. Plasmide contenant l'adn qui code pour la sequence d'acides amines du facteur tcf-ii, cellules transformees par ce plasmide et production d'une substance physiologiquement active grace a l'utilisation de ce plasmide

Also Published As

Publication number Publication date
NZ232813A (en) 1992-08-26
EP0462277A1 (de) 1991-12-27
AU5177490A (en) 1990-10-09
HU211229A9 (en) 1995-11-28
HUT58797A (en) 1992-03-30
DE69019962T2 (de) 1995-11-23
FI102681B (fi) 1999-01-29
WO1990010651A1 (fr) 1990-09-20
CA2049017C (en) 1998-10-27
KR960009054B1 (ko) 1996-07-10
ATE123498T1 (de) 1995-06-15
DK0462277T3 (da) 1995-10-30
EP0462277A4 (en) 1992-08-12
IE900863L (en) 1990-09-10
NO180796B (no) 1997-03-17
US6333309B1 (en) 2001-12-25
IE64005B1 (en) 1995-06-28
NO913546D0 (no) 1991-09-09
NO913546L (no) 1991-11-11
US5587359A (en) 1996-12-24
FI914234A0 (fi) 1991-09-09
HU212513B (en) 1996-07-29
KR920701256A (ko) 1992-08-11
FI102681B1 (fi) 1999-01-29
HU902330D0 (en) 1991-12-30
RU2113480C1 (ru) 1998-06-20
ES2075199T3 (es) 1995-10-01
EP0462277B1 (de) 1995-06-07
NO180796C (no) 1997-06-25
RU95110767A (ru) 1997-06-10
JPH0768272B1 (de) 1995-07-26
CA2049017A1 (en) 1990-09-11
AU629314B2 (en) 1992-10-01

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: DAIICHI PHARMACEUTICAL CO., LTD., TOKIO/TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: ATLAS PHARMACEUTICALS, INC., SUNNYVALE, CALIF., US