DE68903056D1 - Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
DE68903056D1
DE68903056D1 DE8989111095T DE68903056T DE68903056D1 DE 68903056 D1 DE68903056 D1 DE 68903056D1 DE 8989111095 T DE8989111095 T DE 8989111095T DE 68903056 T DE68903056 T DE 68903056T DE 68903056 D1 DE68903056 D1 DE 68903056D1
Authority
DE
Germany
Prior art keywords
procyanidol
production
pharmaceutical compositions
compositions containing
oligomeric fractions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989111095T
Other languages
English (en)
Other versions
DE68903056T2 (de
Inventor
Enrico Frangi
Marco Bertani
Giuseppe Mustich
Gianfranco Tuccini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Tecnofarmaci SpA
Original Assignee
Indena SpA
Tecnofarmaci SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA, Tecnofarmaci SpA filed Critical Indena SpA
Publication of DE68903056D1 publication Critical patent/DE68903056D1/de
Application granted granted Critical
Publication of DE68903056T2 publication Critical patent/DE68903056T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Image Analysis (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8989111095T 1988-06-28 1989-06-19 Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. Expired - Fee Related DE68903056T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21134/88A IT1219732B (it) 1988-06-28 1988-06-28 Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono

Publications (2)

Publication Number Publication Date
DE68903056D1 true DE68903056D1 (de) 1992-11-05
DE68903056T2 DE68903056T2 (de) 1993-03-04

Family

ID=11177250

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989111095T Expired - Fee Related DE68903056T2 (de) 1988-06-28 1989-06-19 Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (11)

Country Link
EP (1) EP0348781B1 (de)
JP (1) JP2799734B2 (de)
AT (1) ATE81014T1 (de)
CA (1) CA1337565C (de)
DE (1) DE68903056T2 (de)
ES (1) ES2052819T3 (de)
FI (1) FI92976C (de)
GR (1) GR3006066T3 (de)
IT (1) IT1219732B (de)
NO (1) NO179894C (de)
PT (1) PT90990B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484594A (en) * 1988-06-28 1996-01-16 Tecnofarmaci S.P.A. Process for preparing grapeseed extracts enriched in procyanidol oligomers
FR2722498B1 (fr) 1994-07-12 1996-10-11 Berkem Sa Procede de preparation d'extraits contenant des composes polyphenoliques oligomeres de type catechique a partir de xources vegetales et extraits obtenus
IT1270999B (it) * 1994-07-26 1997-05-26 Indena Spa Formulazioni a base di cumarine e loro uso in campo farmaceutico e cosmetico
US5554645A (en) 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
FR2725447B1 (fr) * 1994-10-11 1996-12-27 Sanofi Sa Procede d'obtention d'oligomeres procyanidoliques
US5702752A (en) * 1996-03-13 1997-12-30 Archer Daniels Midland Company Production of isoflavone enriched fractions from soy protein extracts
US6261565B1 (en) 1996-03-13 2001-07-17 Archer Daniels Midland Company Method of preparing and using isoflavones
US6391310B1 (en) 1996-03-13 2002-05-21 Archer Daniels Midland Company Method of preparing and using isoflavones for the treatment of neurological symptoms
US6297273B1 (en) 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
FR2749303B1 (fr) * 1996-05-30 1998-08-07 Berkem Sa Procede d'extraction de polyphenols catechiques a partir de potentilles extrait obtenu et son utilisation
SK35599A3 (en) * 1996-09-20 1999-08-06 Howard Foundation Dry composition with flavonol content, a beverage containing such composition and its use
US6238673B1 (en) 1996-09-20 2001-05-29 The Howard Foundation Method of producing high flavonol content polyphenol compositions
CA2322860C (en) * 1998-03-12 2010-10-19 Mars, Incorporated Products containing polyphenol(s) and l-arginine to stimulate nitric oxide production
KR100509119B1 (ko) * 1999-07-16 2005-08-18 주식회사 엘지생활건강 프로시아니딘 올리고머를 유효성분으로 하는 약제
US6627232B1 (en) 2000-06-09 2003-09-30 Mars Incorporated Method for extracting cocoa procyanidins
FR2822466B1 (fr) 2001-03-23 2004-07-02 Diana Ingredients Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique
FR2836336B1 (fr) 2002-02-26 2004-08-27 Diana Ingredients Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones
WO2004037276A1 (en) * 2002-10-23 2004-05-06 Tarac Technologies Pty Ltd Method and composition for enhancing vascular function
US20040121059A1 (en) * 2002-10-24 2004-06-24 Navpreet Singh Soy isoflavone concentrate process and product
WO2004080993A1 (ja) * 2003-03-11 2004-09-23 Toyo Shinyaku Co., Ltd. プロアントシアニジン高含有物の製造方法
ITAN20030053A1 (it) * 2003-10-08 2005-04-09 Mauro Angeletti Processo per la produzione di estratto da semi d'uva a basso contenuto di polifenoli monomerici
ITMI20051485A1 (it) * 2005-07-29 2007-01-30 Indena Spa Estratto da semi d'uva ottenibile per frazionamento su resina
CN1923831B (zh) * 2005-09-01 2011-07-06 浙江瑞康生物技术有限公司 葡萄籽多酚生产工艺
JP5281234B2 (ja) * 2006-06-27 2013-09-04 ポーラ化成工業株式会社 毛様体過緊張による疲れ目の改善・予防のための経口投与組成物
EP1913821A1 (de) * 2006-10-20 2008-04-23 Kraft Foods R & D, Inc. Zweigniederlassung München Polyphenolreiche Extrakt aus Pflanzen
JP5661228B2 (ja) * 2007-04-17 2015-01-28 ハウス食品グループ本社株式会社 フェヌグリーク種子加工物およびその製造方法
JP2010533648A (ja) 2007-07-13 2010-10-28 オーシャン スプレー クランベリーズ インコーポレイテッド プロアントシアニジン抽出物を生成するためのプロセス
ITBO20070542A1 (it) * 2007-07-31 2009-02-01 Univ Bologna Alma Mater Metodo per il trattamento di matrici vegetali
PT2189062E (pt) 2008-11-25 2013-10-22 Indena Spa Extratos de planta para utilização como fitoquímicos
US20130210754A1 (en) * 2010-05-28 2013-08-15 Uwe Scheuring Method for producing an enriched extract from vitis vinifera l. leaves
WO2011147989A1 (de) 2010-05-28 2011-12-01 Finzelberg Gmbh & Co. Kg Verfahren zur herstellung eines angereicherten extraktes aus blättern von weinrebengewächsen
CN106455637A (zh) * 2014-05-30 2017-02-22 嘉康利公司 霞多丽葡萄籽提取物
CA3087842A1 (en) 2018-02-02 2019-08-08 Indena S.P.A. Compositions comprising berberine
WO2019162382A1 (en) 2018-02-23 2019-08-29 Indena S.P.A. Cosmetic compositions for protection against light-induced damages

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092743A1 (en) * 1970-06-15 1972-01-28 Aquitaine Invest Pharma Complete extraction of total flavanol gomers from plats -peripheral - venous activity
FR2268518A1 (en) * 1974-04-25 1975-11-21 Aquitaine Invest Pharma Flavonoid extraction from plants - using aq acetone evaporating and extracting a solution of flavonoids in saturated sodium chloride with butanol

Also Published As

Publication number Publication date
NO892673L (no) 1989-12-29
FI92976C (fi) 1995-02-10
EP0348781B1 (de) 1992-09-30
EP0348781A3 (en) 1990-07-11
FI92976B (fi) 1994-10-31
PT90990B (pt) 1994-12-30
FI893117A (fi) 1989-12-29
IT8821134A0 (it) 1988-06-28
EP0348781A2 (de) 1990-01-03
JP2799734B2 (ja) 1998-09-21
IT1219732B (it) 1990-05-24
NO179894B (no) 1996-09-30
FI893117A0 (fi) 1989-06-27
NO179894C (no) 1997-01-08
GR3006066T3 (de) 1993-06-21
ES2052819T3 (es) 1994-07-16
NO892673D0 (no) 1989-06-27
PT90990A (pt) 1989-12-29
DE68903056T2 (de) 1993-03-04
CA1337565C (en) 1995-11-14
ATE81014T1 (de) 1992-10-15
JPH0248593A (ja) 1990-02-19

Similar Documents

Publication Publication Date Title
DE68903056D1 (de) Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES2075147T3 (es) Acido 2-o-alfa-d-glucopiranosil-l-ascorbico cristalino, y su preparacion y usos.
DE339237T1 (de) Phenol-substituierte gem-diphosphonat-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.
PT94761A (pt) Processo para a preparacao de muteinas da eritropoetina humana e de composicoes farmaceuticas que as contem
ATA112089A (de) Harzadsorbat ranitidinpräparate und verfahren zu ihrer herstellung
ES2024400A4 (es) Extracto de hojas de ginkgo biloba, su metodo de preparacion y productos que contienen el extracto.
DE3682331D1 (de) Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
DE3882383T2 (de) Phospholipidische Komplexe aus Vitis Vinifera-Extrakten, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische und kosmetische Zusammensetzungen.
DE3582952D1 (de) Dihydropyridin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE3863904D1 (de) Pharmazeutische zusammensetzungen mit gehalt an einem derivat der 3-hydroxy-buttersaeure, ausgewaehlt aus den oligomeren dieser saeure und den estern dieser saeure oder dieser oligomere mit dem 1,3-butan-diol.
DE68910785T2 (de) Membrane zum Trennen von flüssigen Wasser-Alkohol-Gemischen und Verfahren zu ihrer Herstellung.
ATE76434T1 (de) Immunstimulierend wirkende polysaccharide aus zellkulturen von echinacea purpurea (linne) moench und echinacea angustifolia (de vandolle), verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen.
GR3007688T3 (de)
DE3767849D1 (de) Arzneimittel zur vorbeugung und behandlung der alkoholischen toxicomanie und verfahren zu ihrer herstellung.
DE3767789D1 (de) Substituierte aminodihydrooxazole, -thiazole und -imidazole, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE141929T1 (de) Verfahren zur herstellung von epoxy-hepariden; die so hergestellten produkte und diese enthaltende pharmazeutische zusammensetzungen
DE3889046T2 (de) Copolyamide, enthaltend spiro(bis)indane und verfahren zu ihrer herstellung.
DE3670635D1 (de) Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3586817D1 (de) 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE68917379D1 (de) Verfahren zur Herstellung von Proteinen, die ähnlich dem natürlich-menschlichen Apolipoprotein-E sind.
DE3770551D1 (de) Verfahren zur herstellung eines pulvers mit grosser wundheilungsfaehigkeit aus der rinde des baumes namens "mimosa tenuiflora poir".
AU3803189A (en) Ultrathin-skinned asymmetric membranes by immiscible solvent treatment
ATE118524T1 (de) Flüssige kohlenwasserstoffgemische mit hohen ein- und zweikernigen aromatenanteilen.
AT385720B (de) Vulkanisierform zur herstellung von ringfoermigen polymeren erzeugnissen, insbesondere von zahnriemen
PT84176A (pt) Process for preparing 2,6-dioxabicyclo ]3.3.o" octane derivati ves useful as medicaments

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee