ATE81014T1 - Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents
Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE81014T1 ATE81014T1 AT89111095T AT89111095T ATE81014T1 AT E81014 T1 ATE81014 T1 AT E81014T1 AT 89111095 T AT89111095 T AT 89111095T AT 89111095 T AT89111095 T AT 89111095T AT E81014 T1 ATE81014 T1 AT E81014T1
- Authority
- AT
- Austria
- Prior art keywords
- procyanidol
- preparation
- pharmaceutical compositions
- compositions containing
- oligomeric fractions
- Prior art date
Links
- SBZWTSHAFILOTE-SOUVJXGZSA-N (2R,3S,4S)-leucocyanidin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3[C@H](O)[C@@H]2O)=CC=C(O)C(O)=C1 SBZWTSHAFILOTE-SOUVJXGZSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 235000014787 Vitis vinifera Nutrition 0.000 abstract 1
- 240000006365 Vitis vinifera Species 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 235000002532 grape seed extract Nutrition 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 238000000108 ultra-filtration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compounds Of Unknown Constitution (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Image Analysis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21134/88A IT1219732B (it) | 1988-06-28 | 1988-06-28 | Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono |
| EP89111095A EP0348781B1 (de) | 1988-06-28 | 1989-06-19 | Procyanidol-oligomerische Fraktionen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE81014T1 true ATE81014T1 (de) | 1992-10-15 |
Family
ID=11177250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89111095T ATE81014T1 (de) | 1988-06-28 | 1989-06-19 | Procyanidol-oligomerische fraktionen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0348781B1 (de) |
| JP (1) | JP2799734B2 (de) |
| AT (1) | ATE81014T1 (de) |
| CA (1) | CA1337565C (de) |
| DE (1) | DE68903056T2 (de) |
| ES (1) | ES2052819T3 (de) |
| FI (1) | FI92976C (de) |
| GR (1) | GR3006066T3 (de) |
| IT (1) | IT1219732B (de) |
| NO (1) | NO179894C (de) |
| PT (1) | PT90990B (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484594A (en) * | 1988-06-28 | 1996-01-16 | Tecnofarmaci S.P.A. | Process for preparing grapeseed extracts enriched in procyanidol oligomers |
| FR2722498B1 (fr) | 1994-07-12 | 1996-10-11 | Berkem Sa | Procede de preparation d'extraits contenant des composes polyphenoliques oligomeres de type catechique a partir de xources vegetales et extraits obtenus |
| IT1270999B (it) * | 1994-07-26 | 1997-05-26 | Indena Spa | Formulazioni a base di cumarine e loro uso in campo farmaceutico e cosmetico |
| US5554645A (en) | 1994-10-03 | 1996-09-10 | Mars, Incorporated | Antineoplastic cocoa extracts and methods for making and using the same |
| FR2725447B1 (fr) * | 1994-10-11 | 1996-12-27 | Sanofi Sa | Procede d'obtention d'oligomeres procyanidoliques |
| US6261565B1 (en) | 1996-03-13 | 2001-07-17 | Archer Daniels Midland Company | Method of preparing and using isoflavones |
| US5702752A (en) * | 1996-03-13 | 1997-12-30 | Archer Daniels Midland Company | Production of isoflavone enriched fractions from soy protein extracts |
| US6391310B1 (en) | 1996-03-13 | 2002-05-21 | Archer Daniels Midland Company | Method of preparing and using isoflavones for the treatment of neurological symptoms |
| US6297273B1 (en) | 1996-04-02 | 2001-10-02 | Mars, Inc. | Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions |
| FR2749303B1 (fr) * | 1996-05-30 | 1998-08-07 | Berkem Sa | Procede d'extraction de polyphenols catechiques a partir de potentilles extrait obtenu et son utilisation |
| GB2317889A (en) * | 1996-09-20 | 1998-04-08 | Howard Foundation | Producing polyphenols compositions from grape extracts |
| US6238673B1 (en) | 1996-09-20 | 2001-05-29 | The Howard Foundation | Method of producing high flavonol content polyphenol compositions |
| JP2002505864A (ja) * | 1998-03-12 | 2002-02-26 | マーズ インコーポレーテッド | 窒素酸化物の生成を促進するためにポリフェノールおよびl−アルギニンを含有する製品 |
| KR100509119B1 (ko) * | 1999-07-16 | 2005-08-18 | 주식회사 엘지생활건강 | 프로시아니딘 올리고머를 유효성분으로 하는 약제 |
| US6627232B1 (en) | 2000-06-09 | 2003-09-30 | Mars Incorporated | Method for extracting cocoa procyanidins |
| FR2822466B1 (fr) | 2001-03-23 | 2004-07-02 | Diana Ingredients | Fraction phenolique riche en phloridzine et son utilisation en tant qu'agent cosmetique, alimentaire ou nutraceutique |
| FR2836336B1 (fr) | 2002-02-26 | 2004-08-27 | Diana Ingredients | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
| WO2004037276A1 (en) * | 2002-10-23 | 2004-05-06 | Tarac Technologies Pty Ltd | Method and composition for enhancing vascular function |
| AU2003284189A1 (en) * | 2002-10-24 | 2004-05-13 | Solae Llc | Soy isoflavone concentrate process and product |
| WO2004080993A1 (ja) * | 2003-03-11 | 2004-09-23 | Toyo Shinyaku Co., Ltd. | プロアントシアニジン高含有物の製造方法 |
| ITAN20030053A1 (it) * | 2003-10-08 | 2005-04-09 | Mauro Angeletti | Processo per la produzione di estratto da semi d'uva a basso contenuto di polifenoli monomerici |
| ITMI20051485A1 (it) * | 2005-07-29 | 2007-01-30 | Indena Spa | Estratto da semi d'uva ottenibile per frazionamento su resina |
| CN1923831B (zh) * | 2005-09-01 | 2011-07-06 | 浙江瑞康生物技术有限公司 | 葡萄籽多酚生产工艺 |
| JP5281234B2 (ja) * | 2006-06-27 | 2013-09-04 | ポーラ化成工業株式会社 | 毛様体過緊張による疲れ目の改善・予防のための経口投与組成物 |
| EP1913821A1 (de) * | 2006-10-20 | 2008-04-23 | Kraft Foods R & D, Inc. Zweigniederlassung München | Polyphenolreiche Extrakt aus Pflanzen |
| JP5661228B2 (ja) * | 2007-04-17 | 2015-01-28 | ハウス食品グループ本社株式会社 | フェヌグリーク種子加工物およびその製造方法 |
| EP2175731A4 (de) | 2007-07-13 | 2014-07-02 | Ocean Spray Cranberries Inc | Verfahren zur herstellung eines proanthocyanidin-extrakts |
| ITBO20070542A1 (it) * | 2007-07-31 | 2009-02-01 | Univ Bologna Alma Mater | Metodo per il trattamento di matrici vegetali |
| PT2189062E (pt) * | 2008-11-25 | 2013-10-22 | Indena Spa | Extratos de planta para utilização como fitoquímicos |
| BR112012030134B1 (pt) * | 2010-05-28 | 2021-06-01 | Boehringer Ingelheim International Gmbh | Processo para preparação de um extrato de folhas de vitis vinifera l |
| WO2011147989A1 (de) | 2010-05-28 | 2011-12-01 | Finzelberg Gmbh & Co. Kg | Verfahren zur herstellung eines angereicherten extraktes aus blättern von weinrebengewächsen |
| CN106455637A (zh) * | 2014-05-30 | 2017-02-22 | 嘉康利公司 | 霞多丽葡萄籽提取物 |
| EP3746054B1 (de) | 2018-02-02 | 2023-06-14 | Indena S.p.A. | Zusammensetzungen mit berberin |
| US20210322297A9 (en) | 2018-02-23 | 2021-10-21 | Givaudan Italia S.P.A | Cosmetic compositions for protection against light-induced damages |
| EP4271210B1 (de) * | 2020-12-30 | 2024-10-30 | Distillerie Bonollo Umberto - S.p.A. Con Sigla "U.B. S.p.A." | Verfahren zur herstellung von traubenkernextrakten und die so gewonnenen extrakte |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2092743A1 (en) * | 1970-06-15 | 1972-01-28 | Aquitaine Invest Pharma | Complete extraction of total flavanol gomers from plats -peripheral - venous activity |
| FR2268518A1 (en) * | 1974-04-25 | 1975-11-21 | Aquitaine Invest Pharma | Flavonoid extraction from plants - using aq acetone evaporating and extracting a solution of flavonoids in saturated sodium chloride with butanol |
-
1988
- 1988-06-28 IT IT21134/88A patent/IT1219732B/it active
-
1989
- 1989-06-19 EP EP89111095A patent/EP0348781B1/de not_active Expired - Lifetime
- 1989-06-19 DE DE8989111095T patent/DE68903056T2/de not_active Expired - Fee Related
- 1989-06-19 ES ES89111095T patent/ES2052819T3/es not_active Expired - Lifetime
- 1989-06-19 AT AT89111095T patent/ATE81014T1/de not_active IP Right Cessation
- 1989-06-27 NO NO892673A patent/NO179894C/no unknown
- 1989-06-27 FI FI893117A patent/FI92976C/fi not_active IP Right Cessation
- 1989-06-27 JP JP1165135A patent/JP2799734B2/ja not_active Expired - Fee Related
- 1989-06-27 PT PT90990A patent/PT90990B/pt not_active IP Right Cessation
- 1989-06-27 CA CA000603989A patent/CA1337565C/en not_active Expired - Fee Related
-
1992
- 1992-10-22 GR GR920402393T patent/GR3006066T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1337565C (en) | 1995-11-14 |
| DE68903056T2 (de) | 1993-03-04 |
| JP2799734B2 (ja) | 1998-09-21 |
| NO892673L (no) | 1989-12-29 |
| FI92976C (fi) | 1995-02-10 |
| PT90990A (pt) | 1989-12-29 |
| JPH0248593A (ja) | 1990-02-19 |
| IT1219732B (it) | 1990-05-24 |
| GR3006066T3 (de) | 1993-06-21 |
| DE68903056D1 (de) | 1992-11-05 |
| FI92976B (fi) | 1994-10-31 |
| NO892673D0 (no) | 1989-06-27 |
| EP0348781A3 (en) | 1990-07-11 |
| IT8821134A0 (it) | 1988-06-28 |
| EP0348781B1 (de) | 1992-09-30 |
| FI893117L (fi) | 1989-12-29 |
| ES2052819T3 (es) | 1994-07-16 |
| EP0348781A2 (de) | 1990-01-03 |
| NO179894C (no) | 1997-01-08 |
| FI893117A0 (fi) | 1989-06-27 |
| NO179894B (no) | 1996-09-30 |
| PT90990B (pt) | 1994-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |