DE637241T1 - Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums. - Google Patents

Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums.

Info

Publication number
DE637241T1
DE637241T1 DE0637241T DE93912028T DE637241T1 DE 637241 T1 DE637241 T1 DE 637241T1 DE 0637241 T DE0637241 T DE 0637241T DE 93912028 T DE93912028 T DE 93912028T DE 637241 T1 DE637241 T1 DE 637241T1
Authority
DE
Germany
Prior art keywords
acid
substance
inhibitory effect
synergistic combination
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0637241T
Other languages
English (en)
Inventor
Arne Torsten Eek
Sven Erik Sjoestrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26661401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE637241(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9201297A external-priority patent/SE9201297D0/xx
Priority claimed from SE9300029A external-priority patent/SE9300029D0/xx
Application filed by Astra AB filed Critical Astra AB
Publication of DE637241T1 publication Critical patent/DE637241T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06066—Needles, e.g. needle tip configurations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30092—Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0023—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0023—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
    • A61F2210/0047—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply heated by light
DE0637241T 1992-04-24 1993-04-20 Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums. Pending DE637241T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9201297A SE9201297D0 (sv) 1992-04-24 1992-04-24 Synergistic combination
SE9300029A SE9300029D0 (sv) 1993-01-08 1993-01-08 Synergistic combination ii
PCT/SE1993/000327 WO1993021920A1 (en) 1992-04-24 1993-04-20 Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic

Publications (1)

Publication Number Publication Date
DE637241T1 true DE637241T1 (de) 1997-09-11

Family

ID=26661401

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0637241T Pending DE637241T1 (de) 1992-04-24 1993-04-20 Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums.
DE69328967T Revoked DE69328967T2 (de) 1992-04-24 1993-04-20 Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69328967T Revoked DE69328967T2 (de) 1992-04-24 1993-04-20 Synergistische kombination einer substanz mit hemmwirkung auf die magensäuresekretion und eines säureinstabilen antibiotikums

Country Status (39)

Country Link
US (3) US5599794A (de)
EP (2) EP0637241B1 (de)
JP (1) JPH07505901A (de)
KR (1) KR100340165B1 (de)
CN (1) CN1041798C (de)
AP (1) AP466A (de)
AT (1) ATE194286T1 (de)
AU (1) AU669903B2 (de)
CA (1) CA2133762C (de)
CZ (1) CZ291201B6 (de)
DE (2) DE637241T1 (de)
DK (1) DK0637241T3 (de)
DZ (1) DZ1683A1 (de)
EE (1) EE03149B1 (de)
ES (1) ES2100135T3 (de)
FI (1) FI944953A (de)
GR (2) GR970300011T1 (de)
HK (1) HK1008296A1 (de)
HR (1) HRP930755B1 (de)
HU (1) HUT71225A (de)
IL (1) IL105155A (de)
IS (1) IS3990A (de)
LV (1) LV12625B (de)
MA (1) MA22878A1 (de)
MY (1) MY121189A (de)
NO (1) NO314288B1 (de)
NZ (1) NZ252759A (de)
PL (1) PL173485B1 (de)
PT (1) PT637241E (de)
RO (1) RO115780B1 (de)
RU (1) RU2143899C1 (de)
SG (1) SG52485A1 (de)
SI (1) SI9300219B (de)
SK (1) SK282420B6 (de)
TN (1) TNSN93040A1 (de)
TW (1) TW276996B (de)
UA (1) UA43830C2 (de)
WO (1) WO1993021920A1 (de)
YU (1) YU49091B (de)

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SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
CN1061232C (zh) * 1996-04-12 2001-01-31 马理国 一种治疗胃炎、溃疡的药物组合物
SI9700186B (sl) 1997-07-14 2006-10-31 Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin
ATE281178T1 (de) * 1997-07-25 2004-11-15 Altana Pharma Ag Protonenpumpenhemmer als kombinationstherapeutika mit antibakterielle wirkenden substanzen
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
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CA2362930C (en) * 1999-02-26 2010-10-05 Nitromed, Inc. Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use
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HUP0302466A2 (hu) * 2000-02-29 2003-11-28 Teva Pharmaceutical Industries Ltd. Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
CA2413923A1 (en) * 2000-03-09 2001-09-13 Andrew Ilchyshyn Treatment of inflammatory dermatoses comprising erythromycin or clarythromycin metronidazole and a gastrointestinal hydrogen pump inhibitor
EP1133987A1 (de) * 2000-03-09 2001-09-19 Ian Whitcroft Behandlung von entzündlichen Dermatosen mit Erythromycin oder Clarithromycin, Metronidazol und einem Wasserstoffpumpehemmer
DK1267840T3 (da) * 2000-03-28 2009-09-07 Sandoz Ag Granulerede partikler med maskeret smag
SE0002476D0 (sv) 2000-06-30 2000-06-30 Astrazeneca Ab New compounds
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
WO2002026210A2 (en) * 2000-09-29 2002-04-04 Geneva Pharmaceuticals Inc. Proton pump inhibitor formulation
SE0103695D0 (sv) 2001-11-07 2001-11-07 Thomas Boren A novel non-antibiotic strategy against OGIP infections based on a cereal product
WO2003063927A2 (en) * 2001-11-16 2003-08-07 Eisai Co. Ltd Compositions and methods to treat gastrointestinal disorders
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
JP4634144B2 (ja) * 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
JP2006516574A (ja) * 2003-02-05 2006-07-06 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール安定化方法
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
US20040185092A1 (en) * 2003-03-18 2004-09-23 Yih Ming Hsiao Pharmaceutical preparations of omeprazole and/or clarithromycin for oral use
AR045062A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas
MXPA06000524A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido.
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
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Also Published As

Publication number Publication date
SI9300219A (sl) 1993-12-31
CA2133762C (en) 2000-08-01
MA22878A1 (fr) 1993-12-31
GR970300011T1 (en) 1997-05-31
CA2133762A1 (en) 1993-11-11
MY121189A (en) 2006-01-28
RO115780B1 (ro) 2000-06-30
DZ1683A1 (fr) 2002-02-17
US5633244A (en) 1997-05-27
NO944010D0 (no) 1994-10-21
UA43830C2 (uk) 2002-01-15
HK1008296A1 (en) 1999-05-07
YU27593A (sh) 1996-10-09
AU669903B2 (en) 1996-06-27
IL105155A (en) 1999-05-09
CZ291201B6 (cs) 2003-01-15
ATE194286T1 (de) 2000-07-15
ES2100135T1 (es) 1997-06-16
CZ259394A3 (en) 1995-08-16
NO944010L (no) 1994-10-21
PL173485B1 (pl) 1998-03-31
KR100340165B1 (ko) 2002-10-04
IL105155A0 (en) 1993-07-08
SI9300219B (en) 2001-12-31
WO1993021920A1 (en) 1993-11-11
US5629305A (en) 1997-05-13
EE03149B1 (et) 1999-02-15
DK0637241T3 (da) 2000-09-11
JPH07505901A (ja) 1995-06-29
LV12625A (en) 2001-03-20
CN1081614A (zh) 1994-02-09
YU49091B (sh) 2003-12-31
RU2143899C1 (ru) 2000-01-10
HRP930755B1 (en) 2001-04-30
HRP930755A2 (en) 1994-10-31
GR3034470T3 (en) 2000-12-29
DE69328967T2 (de) 2000-12-07
PT637241E (pt) 2000-10-31
ES2100135T3 (es) 2000-11-16
NZ252759A (en) 1996-12-20
EP0637241B1 (de) 2000-07-05
LV12625B (en) 2001-07-20
TNSN93040A1 (fr) 1994-03-17
AP466A (en) 1996-03-05
HUT71225A (en) 1995-11-28
EP0956857A3 (de) 2003-11-26
HU9403069D0 (en) 1994-12-28
TW276996B (de) 1996-06-01
SG52485A1 (en) 1998-09-28
NO314288B1 (no) 2003-03-03
AP9300518A0 (en) 1993-04-30
CN1041798C (zh) 1999-01-27
AU4273793A (en) 1993-11-29
SK127594A3 (en) 1995-04-12
FI944953A0 (fi) 1994-10-21
DE69328967D1 (de) 2000-08-10
FI944953A (fi) 1994-10-21
SK282420B6 (sk) 2002-01-07
EP0956857A2 (de) 1999-11-17
EP0637241A1 (de) 1995-02-08
IS3990A (is) 1993-10-25
US5599794A (en) 1997-02-04

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