ATE114114T1 - Verwendung von benzimidazol-derivaten als antibakterielle mittel. - Google Patents
Verwendung von benzimidazol-derivaten als antibakterielle mittel.Info
- Publication number
- ATE114114T1 ATE114114T1 AT90301256T AT90301256T ATE114114T1 AT E114114 T1 ATE114114 T1 AT E114114T1 AT 90301256 T AT90301256 T AT 90301256T AT 90301256 T AT90301256 T AT 90301256T AT E114114 T1 ATE114114 T1 AT E114114T1
- Authority
- AT
- Austria
- Prior art keywords
- antibacterial agents
- benzimidazole derivatives
- stands
- hydrogen
- campylobacter
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000589876 Campylobacter Species 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3237489 | 1989-02-10 | ||
| JP23923389 | 1989-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE114114T1 true ATE114114T1 (de) | 1994-12-15 |
Family
ID=26370930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90301256T ATE114114T1 (de) | 1989-02-10 | 1990-02-06 | Verwendung von benzimidazol-derivaten als antibakterielle mittel. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5013743A (de) |
| EP (1) | EP0382489B1 (de) |
| AT (1) | ATE114114T1 (de) |
| CA (1) | CA2009741C (de) |
| DE (1) | DE69014141T2 (de) |
| DK (1) | DK0382489T3 (de) |
| ES (1) | ES2066120T3 (de) |
| FI (2) | FI100168B (de) |
| GR (1) | GR3014973T3 (de) |
| NO (1) | NO900639L (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5338723A (en) * | 1989-10-13 | 1994-08-16 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| ES2169022T3 (es) * | 1990-09-14 | 2002-07-01 | Byk Gulden Lomberg Chem Fab | Utilizacion de derivados de (piridil-metil-sulfinil)-1-h-bencimidazol para el tratamiento de enfermedades provocadas por helicobacter. |
| TW209174B (de) * | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
| IS3990A (is) * | 1992-04-24 | 1993-10-25 | Ab Astra | Aðferð við að blanda saman efni sem hindrar flæðimagasýru og bakteríueyðandi efnis sem brotnar niður í súru umhverfi |
| US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
| CA2138787A1 (en) * | 1992-07-08 | 1994-01-20 | Clifton Augustus Baile | Alleviating stomach ulcers in swine |
| US5589491A (en) * | 1992-07-28 | 1996-12-31 | Astra Aktiebolag | Injection and injection kit containing omeprazole and its analogs |
| ES2087623T3 (es) * | 1992-08-21 | 1996-07-16 | Eisai Co Ltd | Derivados de bencimidazol como agente antimicrobiano contra campylobacter pylon. |
| EP0673246A1 (de) * | 1992-12-10 | 1995-09-27 | Byk Gulden Lomberg Chemische Fabrik GmbH | Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien |
| JPH06298611A (ja) * | 1993-04-16 | 1994-10-25 | Nippon Chemiphar Co Ltd | 抗菌剤 |
| JPH08512037A (ja) * | 1993-06-29 | 1996-12-17 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換されたアリールチオアルキルチオピリジン |
| US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| CA2317439A1 (en) | 1998-01-14 | 1999-07-22 | Wayne J. Brouillette | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
| US6861448B2 (en) * | 1998-01-14 | 2005-03-01 | Virtual Drug Development, Inc. | NAD synthetase inhibitors and uses thereof |
| FI104384B (fi) | 1998-06-05 | 2000-01-14 | Valmet Corp | Laitteisto ja menetelmä viiraveden ja tuoremassan sekoittamiseksi viirakaivon jälkeisessä kanavassa |
| US7396841B2 (en) | 2000-08-18 | 2008-07-08 | Takeda Pharmaceutical Company Limited | Injections |
| KR20040025677A (ko) * | 2001-09-18 | 2004-03-24 | 제리아 신야쿠 고교 가부시키 가이샤 | 벤즈이미다졸 유도체 |
| US9358214B2 (en) * | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| MXPA04007169A (es) * | 2002-01-25 | 2004-10-29 | Santarus Inc | Suministro transmucosal de inhibidores de bomba de protones. |
| US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
| US20050220870A1 (en) * | 2003-02-20 | 2005-10-06 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
| TWI398273B (zh) * | 2003-07-18 | 2013-06-11 | Santarus Inc | 用於抑制酸分泌之醫藥調配物及其製備及使用之方法 |
| US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
| US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
| EP1718303A4 (de) * | 2004-02-10 | 2010-09-01 | Santarus Inc | Kombination eines protonenpumpenhemmers, puffermittels und einem nichtsteroidalen entzündungshemmenden mittel |
| AU2005249367A1 (en) * | 2004-04-16 | 2005-12-15 | Santarus, Inc. | Combination of proton pump inhibitor, buffering agent, and prokinetic agent |
| US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US20060024362A1 (en) | 2004-07-29 | 2006-02-02 | Pawan Seth | Composition comprising a benzimidazole and process for its manufacture |
| US8747895B2 (en) * | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| CA2624179A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties |
| ATE533757T1 (de) * | 2006-03-10 | 2011-12-15 | Arigen Pharmaceuticals Inc | Neues pyridinderivat mit wirkung gegen helicobacter pylori |
| CA2654402A1 (en) * | 2006-06-01 | 2007-12-06 | Adel Penhasi | Multiple unit pharmaceutical formulation |
| JP2009539866A (ja) * | 2006-06-05 | 2009-11-19 | オースペックス・ファーマシューティカルズ・インコーポレイテッド | 置換エリスロマイシンアナログの調製および有用性 |
| WO2008067037A2 (en) | 2006-10-05 | 2008-06-05 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
| US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
| WO2008057802A2 (en) | 2006-10-27 | 2008-05-15 | The Curators Of The University Of Missouri | Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same |
| JP5543432B2 (ja) * | 2009-04-09 | 2014-07-09 | リンク・ジェノミクス株式会社 | ピリジンチオ誘導体及びそれを含有する抗ヘリコバクター・ピロリ作用を有する医薬組成物 |
| SG10201407965XA (en) | 2009-12-02 | 2015-02-27 | Aptalis Pharma Ltd | Fexofenadine microcapsules and compositions containing them |
| US20110212171A1 (en) * | 2010-01-08 | 2011-09-01 | Eurand, Inc. | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
| EP3288556A4 (de) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Oral zerfallende zusammensetzungen |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| EP4598528A1 (de) | 2022-10-04 | 2025-08-13 | Arsenil Zabirnyk | Hemmung der verkalkung der aortenklappe |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| JP2694361B2 (ja) * | 1989-02-09 | 1997-12-24 | アストラ アクチエボラグ | 抗菌剤 |
-
1990
- 1990-02-06 ES ES90301256T patent/ES2066120T3/es not_active Expired - Lifetime
- 1990-02-06 DK DK90301256.5T patent/DK0382489T3/da active
- 1990-02-06 EP EP90301256A patent/EP0382489B1/de not_active Expired - Lifetime
- 1990-02-06 DE DE69014141T patent/DE69014141T2/de not_active Expired - Lifetime
- 1990-02-06 AT AT90301256T patent/ATE114114T1/de active
- 1990-02-09 CA CA002009741A patent/CA2009741C/en not_active Expired - Lifetime
- 1990-02-09 NO NO90900639A patent/NO900639L/no unknown
- 1990-02-09 FI FI900662A patent/FI100168B/fi active IP Right Grant
- 1990-02-12 US US07/478,405 patent/US5013743A/en not_active Expired - Lifetime
-
1994
- 1994-02-28 FI FI940951A patent/FI104045B/fi active
-
1995
- 1995-02-08 GR GR940403729T patent/GR3014973T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI940951A0 (fi) | 1994-02-28 |
| ES2066120T3 (es) | 1995-03-01 |
| CA2009741A1 (en) | 1990-08-10 |
| FI104045B1 (fi) | 1999-11-15 |
| US5013743A (en) | 1991-05-07 |
| EP0382489A3 (de) | 1991-06-12 |
| NO900639L (no) | 1990-08-13 |
| DE69014141D1 (de) | 1994-12-22 |
| EP0382489A2 (de) | 1990-08-16 |
| NO900639D0 (no) | 1990-02-09 |
| FI100168B (fi) | 1997-10-15 |
| FI940951L (fi) | 1994-02-28 |
| EP0382489B1 (de) | 1994-11-17 |
| DE69014141T2 (de) | 1995-05-24 |
| FI900662A0 (fi) | 1990-02-09 |
| GR3014973T3 (en) | 1995-05-31 |
| DK0382489T3 (da) | 1995-01-16 |
| CA2009741C (en) | 1999-03-23 |
| FI104045B (fi) | 1999-11-15 |
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