DE60329280D1 - 10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien - Google Patents

10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien

Info

Publication number
DE60329280D1
DE60329280D1 DE60329280T DE60329280T DE60329280D1 DE 60329280 D1 DE60329280 D1 DE 60329280D1 DE 60329280 T DE60329280 T DE 60329280T DE 60329280 T DE60329280 T DE 60329280T DE 60329280 D1 DE60329280 D1 DE 60329280D1
Authority
DE
Germany
Prior art keywords
group
hydrogen atom
resistant bacteria
pyrrolidinyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60329280T
Other languages
English (en)
Inventor
Yoshikazu Asahina
Masaya Takei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60329280D1 publication Critical patent/DE60329280D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60329280T 2002-03-18 2003-03-13 10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien Expired - Lifetime DE60329280D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002074783 2002-03-18
JP2002369205 2002-12-20
PCT/JP2003/002967 WO2003078439A1 (fr) 2002-03-18 2003-03-13 Derive d'acide 10-(3-cyclopropylaminomethyl-1-pyrrolidinyl)pyridobenzoxazinecarboxylique efficace contre les bacteries resistantes

Publications (1)

Publication Number Publication Date
DE60329280D1 true DE60329280D1 (de) 2009-10-29

Family

ID=28043757

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60329280T Expired - Lifetime DE60329280D1 (de) 2002-03-18 2003-03-13 10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien

Country Status (14)

Country Link
US (1) US7153851B2 (de)
EP (1) EP1486500B1 (de)
JP (1) JP4468701B2 (de)
KR (1) KR20040094806A (de)
CN (1) CN1653071A (de)
AT (1) ATE443064T1 (de)
AU (1) AU2003213335B8 (de)
BR (1) BR0308643A (de)
CA (1) CA2478763A1 (de)
DE (1) DE60329280D1 (de)
MX (1) MXPA04009026A (de)
NO (1) NO20043850L (de)
NZ (1) NZ535182A (de)
WO (1) WO2003078439A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1666477T3 (pl) * 2003-09-10 2013-11-29 Kyorin Seiyaku Kk Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
NZ533360A (en) * 2004-06-04 2007-02-23 Ind Res Ltd Improved method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds
WO2006009143A1 (ja) * 2004-07-21 2006-01-26 Kyorin Pharmaceutical Co., Ltd. （３ｓ）－３－ヒドロキシメチル－７－オキソピリドベンゾオキサジン－６－カルボン酸エステルの製造方法
GB0428250D0 (en) * 2004-12-23 2005-01-26 Novartis Ag Organic compounds
WO2007102567A1 (ja) 2006-03-09 2007-09-13 Kyorin Pharmaceutical Co., Ltd. 3,4-ジ置換ピロリジン誘導体の製造方法及び製造中間体
CA2786646A1 (en) * 2010-01-08 2011-07-14 Kyorin Pharmaceutical Co., Ltd. Method for producing 3,4-disubstituted pyrrolidine derivative and production intermediate thereof
BR112012030657A2 (pt) * 2010-05-31 2015-09-29 Kyorin Seiyaku Kk método para produzir derivado de 3-substituído-4-fluoropirrolidina
CA2815952A1 (en) 2010-10-25 2012-05-03 Kyorin Pharmaceutical Co., Ltd. Method for producing 3,4-disubstituted pyrrolidine derivative
CN102276628A (zh) * 2011-06-21 2011-12-14 周崇科 氟喹诺酮类化合物及其合成方法
JP5651812B1 (ja) * 2013-04-25 2015-01-14 杏林製薬株式会社 固形医薬組成物
KR102532681B1 (ko) * 2015-03-13 2023-05-15 교린 세이야꾸 가부시키 가이샤 호흡기 감염증 치료제
GB201708606D0 (en) * 2017-05-30 2017-07-12 King S College London Antibiotic resistance breakers
KR20240096794A (ko) * 2017-06-16 2024-06-26 교린 세이야꾸 가부시키 가이샤 흡인성 폐렴, 폐화농증 또는 폐농양의 치료제
CN112194667B (zh) * 2020-11-06 2021-08-17 湖南科技大学 取代1,4-苯并噁嗪并二氮卓类化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
JPS62155282A (ja) * 1985-12-27 1987-07-10 Sankyo Co Ltd ピリドベンゾオキサジンカルボン酸誘導体
ID16655A (id) * 1996-04-24 1997-10-30 Daiichi Seiyaku Co Turunan-turunan sikloalkilaminometilpirolidina
JPH10287669A (ja) * 1997-04-10 1998-10-27 Dai Ichi Seiyaku Co Ltd 置換アミノメチルピロリジン誘導体

Also Published As

Publication number Publication date
EP1486500A1 (de) 2004-12-15
EP1486500B1 (de) 2009-09-16
JP4468701B2 (ja) 2010-05-26
BR0308643A (pt) 2005-02-09
CN1653071A (zh) 2005-08-10
NZ535182A (en) 2006-02-24
AU2003213335B8 (en) 2009-04-02
NO20043850L (no) 2004-09-14
WO2003078439A1 (fr) 2003-09-25
MXPA04009026A (es) 2005-01-25
AU2003213335A1 (en) 2003-09-29
EP1486500A4 (de) 2006-02-08
CA2478763A1 (en) 2003-09-25
KR20040094806A (ko) 2004-11-10
ATE443064T1 (de) 2009-10-15
AU2003213335B2 (en) 2008-09-11
JPWO2003078439A1 (ja) 2005-07-14
US7153851B2 (en) 2006-12-26
US20050182052A1 (en) 2005-08-18

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