DE60317045D1 - Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen - Google Patents

Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen

Info

Publication number
DE60317045D1
DE60317045D1 DE60317045T DE60317045T DE60317045D1 DE 60317045 D1 DE60317045 D1 DE 60317045D1 DE 60317045 T DE60317045 T DE 60317045T DE 60317045 T DE60317045 T DE 60317045T DE 60317045 D1 DE60317045 D1 DE 60317045D1
Authority
DE
Germany
Prior art keywords
proliferation
nucleic acids
colorectal cells
analyzing problems
cell proliferative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60317045T
Other languages
English (en)
Other versions
DE60317045T2 (de
Inventor
Peter Adorjan
Matthias Burger
Sabine Maier
Ralf Lesche
Susan Cottrell
Vos Theo De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epigenomics AG
Original Assignee
Epigenomics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics AG filed Critical Epigenomics AG
Application granted granted Critical
Publication of DE60317045D1 publication Critical patent/DE60317045D1/de
Publication of DE60317045T2 publication Critical patent/DE60317045T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60317045T 2002-02-27 2003-02-13 Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen Expired - Lifetime DE60317045T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02004551 2002-02-27
EP02004551A EP1340818A1 (de) 2002-02-27 2002-02-27 Verfahren und Nukleinsäuren zur Analyse von Kolonkrebszellen
PCT/EP2003/001457 WO2003072812A2 (en) 2002-02-27 2003-02-13 Method and nucleic acids for the analysis of colorectal cell proliferative disorders

Publications (2)

Publication Number Publication Date
DE60317045D1 true DE60317045D1 (de) 2007-12-06
DE60317045T2 DE60317045T2 (de) 2008-08-07

Family

ID=27675653

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60317045T Expired - Lifetime DE60317045T2 (de) 2002-02-27 2003-02-13 Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen
DE60335245T Expired - Lifetime DE60335245D1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
DE60327600T Expired - Lifetime DE60327600D1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebszellen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE60335245T Expired - Lifetime DE60335245D1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
DE60327600T Expired - Lifetime DE60327600D1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebszellen

Country Status (9)

Country Link
US (6) US8691503B2 (de)
EP (4) EP1340818A1 (de)
JP (3) JP2005518218A (de)
AT (3) ATE376596T1 (de)
AU (3) AU2003210265A1 (de)
CA (1) CA2451982A1 (de)
DE (3) DE60317045T2 (de)
ES (2) ES2295607T3 (de)
WO (3) WO2003072812A2 (de)

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US20040029128A1 (en) * 2002-08-08 2004-02-12 Epigenomics, Inc. Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the calcitonin gene
WO2005071111A1 (en) * 2004-01-23 2005-08-04 Lingvitae As Improving polynucleotide ligation reactions
EP1730160A4 (de) * 2004-03-17 2008-04-09 Univ Johns Hopkins Zusammensetzungen zur diagnose von neoplasie und anwendungsverfahren
EP1778865A1 (de) * 2004-06-23 2007-05-02 Epigenomics AG Verfahren und nukleinsäuren zum nachweis der metastasierung proliferativer kolonzellerkrankungen
KR100617649B1 (ko) 2004-09-24 2006-09-04 (주)지노믹트리 대장암 특이적 발현감소 유전자의 메틸화된 프로모터를 함유하는 암 진단용 조성물 및 그 용도
EP3061833B1 (de) * 2004-09-30 2018-03-14 Epigenomics AG Verfahren zur bereitstellung von dna-fragmenten aus einer archivierten probe
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US8445442B2 (en) * 2007-04-26 2013-05-21 University Of Vermont And State Agricultural College CCL18 and CCL3 methods and compositions for detecting and treating cancer
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NZ584514A (en) * 2007-10-19 2012-07-27 Genentech Inc Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates
WO2009052567A1 (en) * 2007-10-23 2009-04-30 Clinical Genomics Pty. Ltd. A method of diagnosing neoplasms - ii
KR100969692B1 (ko) * 2008-01-18 2010-07-14 한국생명공학연구원 대장암 과발현 유전자를 이용한 대장암 진단 마커
WO2010053539A2 (en) * 2008-11-05 2010-05-14 The Texas A&M University System Methods for detecting colorectal diseases and disorders
WO2010070572A1 (en) * 2008-12-18 2010-06-24 Koninklijke Philips Electronics N. V. Method for the detection of dna methylation patterns
CA2826696C (en) 2011-02-02 2019-12-03 Exact Sciences Corporation Digital sequence analysis of dna methylation
WO2013057581A2 (en) * 2011-10-17 2013-04-25 King Abdullah University Of Science And Technology Composite biomarkers for non-invasive screening, diagnosis and prognosis of colorectal cancer
US9598735B2 (en) * 2012-11-14 2017-03-21 JBS Science Inc. Detection of a panel of urine DNA markers for HCC screening and disease management
EP2886659A1 (de) * 2013-12-20 2015-06-24 AIT Austrian Institute of Technology GmbH Genmethylierung basierend auf der Diagnose von Kolorektalkrebs

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Also Published As

Publication number Publication date
US20140179563A1 (en) 2014-06-26
US20050003463A1 (en) 2005-01-06
EP1340818A1 (de) 2003-09-03
DE60317045T2 (de) 2008-08-07
ES2325363T3 (es) 2009-09-02
EP1478778A2 (de) 2004-11-24
WO2003072820A2 (en) 2003-09-04
AU2003248349B2 (en) 2008-05-01
CA2451982A1 (en) 2003-09-04
US20150275312A1 (en) 2015-10-01
AU2003219002A1 (en) 2003-09-09
AU2003248349A1 (en) 2003-09-09
EP1478778B1 (de) 2009-05-13
WO2003072812A2 (en) 2003-09-04
JP2005518220A (ja) 2005-06-23
JP2005518218A (ja) 2005-06-23
US8691503B2 (en) 2014-04-08
WO2003072812A3 (en) 2003-10-23
WO2003072821A2 (en) 2003-09-04
US9988683B2 (en) 2018-06-05
ES2295607T3 (es) 2008-04-16
WO2003072820A3 (en) 2004-04-08
US20060234224A1 (en) 2006-10-19
WO2003072821A3 (en) 2004-04-01
ATE376596T1 (de) 2007-11-15
EP1481095B1 (de) 2010-12-08
DE60335245D1 (de) 2011-01-20
AU2003210265A1 (en) 2003-09-09
US20110046005A1 (en) 2011-02-24
EP1481095A2 (de) 2004-12-01
ATE491038T1 (de) 2010-12-15
US20060246433A1 (en) 2006-11-02
EP1478784B1 (de) 2007-10-24
JP2005518219A (ja) 2005-06-23
EP1478784A2 (de) 2004-11-24
AU2003219002B2 (en) 2008-04-24
DE60327600D1 (de) 2009-06-25
ATE431429T1 (de) 2009-05-15

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