DE60313866T2 - Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür - Google Patents

Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Download PDF

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Publication number
DE60313866T2
DE60313866T2 DE60313866T DE60313866T DE60313866T2 DE 60313866 T2 DE60313866 T2 DE 60313866T2 DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T2 DE60313866 T2 DE 60313866T2
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DE
Germany
Prior art keywords
amino acid
acid amide
amino
activity
polypeptide
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60313866T
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German (de)
English (en)
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DE60313866D1 (de
Inventor
Wilhelmus Hubertus Boesten
Petronella Catharina Raemakers-Franken
Theodorus Sonke
Gerrit Jan Euverink
Pieter Grijpstra
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DSM IP Assets BV
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DSM IP Assets BV
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Publication of DE60313866T2 publication Critical patent/DE60313866T2/de
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60313866T 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Expired - Lifetime DE60313866T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02100711 2002-06-14
EP02100711 2002-06-14
EP02080631 2002-12-20
EP02080631 2002-12-20
PCT/NL2003/000423 WO2003106691A1 (en) 2002-06-14 2003-06-13 POLYPEPTIDES HAVING α- H-α-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME

Publications (2)

Publication Number Publication Date
DE60313866D1 DE60313866D1 (de) 2007-06-28
DE60313866T2 true DE60313866T2 (de) 2008-04-17

Family

ID=29737945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313866T Expired - Lifetime DE60313866T2 (de) 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Country Status (9)

Country Link
US (1) US7371555B2 (enExample)
EP (1) EP1513946B1 (enExample)
JP (1) JP4402587B2 (enExample)
CN (1) CN100471950C (enExample)
AT (1) ATE362544T1 (enExample)
AU (1) AU2003238717A1 (enExample)
DE (1) DE60313866T2 (enExample)
ES (1) ES2285128T3 (enExample)
WO (1) WO2003106691A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
CN1926240B (zh) * 2004-01-19 2010-06-02 帝斯曼知识产权资产管理有限公司 6-氨基己酸的生物化学合成
DE102004013842A1 (de) 2004-03-20 2005-10-13 Degussa Ag Nitrilhydratasen aus Metagenombibliotheken
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
JP5755884B2 (ja) 2008-03-05 2015-07-29 ジェノマティカ, インコーポレイテッド 第一級アルコールを産生する生物
EP2172545A1 (en) 2008-09-24 2010-04-07 DSM IP Assets B.V. Preparation of purified peptide deformylase
MY153590A (en) 2008-12-12 2015-02-26 Celexion Llc Biological synthesis of difunctional alkanes from alpha ketoacids
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
BRPI1013426A2 (pt) 2009-04-30 2016-11-08 Genomatica Inc organismos para produção de 1,3-butanodiol
US8993285B2 (en) 2009-04-30 2015-03-31 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
EP2462221B1 (en) 2009-08-05 2017-02-22 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
CA2787314A1 (en) 2010-01-29 2011-08-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
MX350510B (es) 2010-07-14 2017-09-08 Patheon Austria Gmbh & Co Kg Aminación (r)-selectiva.
JP2013535203A (ja) 2010-07-26 2013-09-12 ジェノマティカ・インコーポレイテッド 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法
CN109337832B (zh) * 2018-03-14 2021-06-15 重庆理工大学 一种耐高氨氮异养硝化-好氧反硝化的苍白杆菌及其应用
CN110317742B (zh) * 2019-03-22 2021-01-01 厦门大学 一株耐铬的石油烃降解菌株Tph3-32及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK261685A (da) * 1985-06-11 1986-12-12 Novo Industri As Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
JPS63129984A (ja) * 1986-11-21 1988-06-02 Toray Ind Inc α−アミノ−ε−カプロラクタム・ラセマ−ゼ
EP0330695B1 (en) * 1987-08-17 1992-11-11 Novo Nordisk A/S Process for preparation of organic chemicals
DE3816063A1 (de) * 1988-05-06 1989-11-23 Schering Ag Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (en) * 1989-02-16 1990-08-22 Stamicarbon B.V. Process for preparation of organic chemicals
NL9100038A (nl) * 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
AU4436900A (en) 1999-04-29 2000-11-17 Dsm N.V. Expression cassette for efficient production of a protein
JP4122416B2 (ja) 2004-02-24 2008-07-23 関西ティー・エル・オー株式会社 α−アミノ−ε−カプロラクタムラセマーゼを用いた、D及びL−アミノ酸アミドの混合物の製造方法、D又はL−アミノ酸の製造方法、D又はL−アミノ酸アミドの製造方法

Also Published As

Publication number Publication date
DE60313866D1 (de) 2007-06-28
WO2003106691A1 (en) 2003-12-24
EP1513946B1 (en) 2007-05-16
AU2003238717A1 (en) 2003-12-31
JP2005529611A (ja) 2005-10-06
CN100471950C (zh) 2009-03-25
EP1513946A1 (en) 2005-03-16
ATE362544T1 (de) 2007-06-15
US7371555B2 (en) 2008-05-13
US20040248274A1 (en) 2004-12-09
CN1675371A (zh) 2005-09-28
ES2285128T3 (es) 2007-11-16
JP4402587B2 (ja) 2010-01-20

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