DE60313866T2 - Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür - Google Patents

Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Download PDF

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Publication number
DE60313866T2
DE60313866T2 DE60313866T DE60313866T DE60313866T2 DE 60313866 T2 DE60313866 T2 DE 60313866T2 DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T2 DE60313866 T2 DE 60313866T2
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DE
Germany
Prior art keywords
amino acid
acid amide
amino
activity
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60313866T
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German (de)
English (en)
Other versions
DE60313866D1 (de
Inventor
Wilhelmus Hubertus Boesten
Petronella Catharina Raemakers-Franken
Theodorus Sonke
Gerrit Jan Euverink
Pieter Grijpstra
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DSM IP Assets BV
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DSM IP Assets BV
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Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE60313866D1 publication Critical patent/DE60313866D1/de
Application granted granted Critical
Publication of DE60313866T2 publication Critical patent/DE60313866T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60313866T 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Expired - Lifetime DE60313866T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02100711 2002-06-14
EP02100711 2002-06-14
EP02080631 2002-12-20
EP02080631 2002-12-20
PCT/NL2003/000423 WO2003106691A1 (en) 2002-06-14 2003-06-13 POLYPEPTIDES HAVING α- H-α-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME

Publications (2)

Publication Number Publication Date
DE60313866D1 DE60313866D1 (de) 2007-06-28
DE60313866T2 true DE60313866T2 (de) 2008-04-17

Family

ID=29737945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313866T Expired - Lifetime DE60313866T2 (de) 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Country Status (9)

Country Link
US (1) US7371555B2 (enExample)
EP (1) EP1513946B1 (enExample)
JP (1) JP4402587B2 (enExample)
CN (1) CN100471950C (enExample)
AT (1) ATE362544T1 (enExample)
AU (1) AU2003238717A1 (enExample)
DE (1) DE60313866T2 (enExample)
ES (1) ES2285128T3 (enExample)
WO (1) WO2003106691A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
DE602005018898D1 (de) * 2004-01-19 2010-03-04 Dsm Ip Assets Bv Biochemische synthese von 6-aminocapronsäure
DE102004013842A1 (de) 2004-03-20 2005-10-13 Degussa Ag Nitrilhydratasen aus Metagenombibliotheken
US7803589B2 (en) 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
SI2262901T1 (sl) 2008-03-05 2019-02-28 Genomatica, Inc. Primarni alkohol producirajoči organizmi
EP2172545A1 (en) 2008-09-24 2010-04-07 DSM IP Assets B.V. Preparation of purified peptide deformylase
CN102317464B (zh) 2008-12-12 2014-10-29 塞莱西翁有限公司 从α-酮酸生物合成双官能烷烃
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
KR102115497B1 (ko) 2009-04-30 2020-05-26 게노마티카 인코포레이티드 1,3-부탄다이올 생산 유기체
AU2010242849A1 (en) 2009-04-30 2011-11-24 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
WO2011017560A1 (en) 2009-08-05 2011-02-10 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
KR20120088753A (ko) 2009-10-23 2012-08-08 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
BR112012018620A2 (pt) 2010-01-29 2015-09-15 Genomatica Inc organismo microbiano de ocorrência não-natural, método para produzir (2-hidroxi-3-metil-4-oxobutoxi) fosfonato, método para produção de p-toluato, método para produzir tereftalato
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
JP5999565B2 (ja) 2010-07-14 2016-09-28 ディーピーエックス ホールディングス ビー．ブイ． （ｒ）−選択的アミノ化
SG187174A1 (en) 2010-07-26 2013-02-28 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CN109337832B (zh) * 2018-03-14 2021-06-15 重庆理工大学 一种耐高氨氮异养硝化-好氧反硝化的苍白杆菌及其应用
CN110317742B (zh) * 2019-03-22 2021-01-01 厦门大学 一株耐铬的石油烃降解菌株Tph3-32及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK261685A (da) * 1985-06-11 1986-12-12 Novo Industri As Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
JPS63129984A (ja) * 1986-11-21 1988-06-02 Toray Ind Inc α−アミノ−ε−カプロラクタム・ラセマ−ゼ
ES2051892T3 (es) * 1987-08-17 1994-07-01 Novo Industri As Procedimiento para preparar productos quimicos organicos.
DE3816063A1 (de) * 1988-05-06 1989-11-23 Schering Ag Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (en) * 1989-02-16 1990-08-22 Stamicarbon B.V. Process for preparation of organic chemicals
NL9100038A (nl) * 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
AU4436900A (en) 1999-04-29 2000-11-17 Dsm N.V. Expression cassette for efficient production of a protein
JP4122416B2 (ja) 2004-02-24 2008-07-23 関西ティー・エル・オー株式会社 α−アミノ−ε−カプロラクタムラセマーゼを用いた、Ｄ及びＬ−アミノ酸アミドの混合物の製造方法、Ｄ又はＬ−アミノ酸の製造方法、Ｄ又はＬ−アミノ酸アミドの製造方法

Also Published As

Publication number Publication date
CN100471950C (zh) 2009-03-25
DE60313866D1 (de) 2007-06-28
US7371555B2 (en) 2008-05-13
AU2003238717A1 (en) 2003-12-31
US20040248274A1 (en) 2004-12-09
ATE362544T1 (de) 2007-06-15
EP1513946B1 (en) 2007-05-16
WO2003106691A1 (en) 2003-12-24
JP2005529611A (ja) 2005-10-06
CN1675371A (zh) 2005-09-28
JP4402587B2 (ja) 2010-01-20
ES2285128T3 (es) 2007-11-16
EP1513946A1 (en) 2005-03-16

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