AU4436900A - Expression cassette for efficient production of a protein - Google Patents

Expression cassette for efficient production of a protein

Info

Publication number
AU4436900A
AU4436900A AU44369/00A AU4436900A AU4436900A AU 4436900 A AU4436900 A AU 4436900A AU 44369/00 A AU44369/00 A AU 44369/00A AU 4436900 A AU4436900 A AU 4436900A AU 4436900 A AU4436900 A AU 4436900A
Authority
AU
Australia
Prior art keywords
protein
expression cassette
efficient production
efficient
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44369/00A
Inventor
Pieter De Geus
Adriana Marina Riemens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Publication of AU4436900A publication Critical patent/AU4436900A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU44369/00A 1999-04-29 2000-04-25 Expression cassette for efficient production of a protein Abandoned AU4436900A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99201373 1999-04-29
EP99201373 1999-04-29
PCT/NL2000/000261 WO2000066751A1 (en) 1999-04-29 2000-04-25 Expression cassette for efficient production of a protein

Publications (1)

Publication Number Publication Date
AU4436900A true AU4436900A (en) 2000-11-17

Family

ID=8240172

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44369/00A Abandoned AU4436900A (en) 1999-04-29 2000-04-25 Expression cassette for efficient production of a protein

Country Status (2)

Country Link
AU (1) AU4436900A (en)
WO (1) WO2000066751A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1186668A1 (en) * 2000-09-08 2002-03-13 Dsm N.V. An enzymatic process for preparing Beta-lactam compounds
EP1409688B1 (en) 2001-07-23 2007-06-20 DSM IP Assets B.V. Nucleic acid sequences encoding enantioselective amidases
DE60313866T2 (en) 2002-06-14 2008-04-17 Dsm Ip Assets B.V. POLYPEPTIDE WITH ALPHA-H ALPHA AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS CODED THEREFOR
US20100143981A1 (en) 2006-12-04 2010-06-10 Rusnak-Mueller Monika Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
WO2011003702A1 (en) 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions
US20150147365A1 (en) 2012-05-31 2015-05-28 Dsm Ip Assets B.V. Oral preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3330003A1 (en) * 1982-10-21 1984-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig DNA SEQUENCE AND STRUCTURES AND METHOD FOR THE PRODUCTION OF PENICILLIN ACYLASE THEREOF
US4839286A (en) * 1983-10-07 1989-06-13 Biotechnica International, Inc. Method of biosynthesis and cells therefor
DE3716957A1 (en) * 1987-05-20 1988-12-01 Boehringer Mannheim Gmbh EXPRESSION VECTOR FOR ADJUSTABLE EXPRESSION OF FOREIGN GENES IN PROKARYONTS
DE69110952T2 (en) * 1990-04-18 1995-11-16 Gist Brocades Nv Penicillin-G-acylase, gene coding therefor and method for producing this enzyme.
ATE402997T1 (en) * 1996-11-05 2008-08-15 Bristol Myers Squibb Co MUTATED PENICILLIN G ACYLASES

Also Published As

Publication number Publication date
WO2000066751A1 (en) 2000-11-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase