DE60311662T2 - 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren - Google Patents
3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren Download PDFInfo
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- DE60311662T2 DE60311662T2 DE60311662T DE60311662T DE60311662T2 DE 60311662 T2 DE60311662 T2 DE 60311662T2 DE 60311662 T DE60311662 T DE 60311662T DE 60311662 T DE60311662 T DE 60311662T DE 60311662 T2 DE60311662 T2 DE 60311662T2
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- Prior art keywords
- hydrogen
- alkoxy
- compounds
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- alkyl
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- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title abstract description 5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP02019336 | 2002-08-29 | ||
| EP02019336 | 2002-08-29 | ||
| PCT/EP2003/009601 WO2004019945A1 (en) | 2002-08-29 | 2003-08-29 | 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
Publications (2)
| Publication Number | Publication Date |
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| DE60311662D1 DE60311662D1 (en) | 2007-03-22 |
| DE60311662T2 true DE60311662T2 (de) | 2007-10-25 |
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| DE (1) | DE60311662T2 (https=) |
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| CN104803974A (zh) | 2004-03-03 | 2015-07-29 | 塔科达有限责任公司 | 新的羟基-6-杂芳基菲啶及其作为pde4抑制剂的用途 |
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| EA026655B1 (ru) | 2011-09-15 | 2017-05-31 | Новартис Аг | 6-ЗАМЕЩЕННЫЕ 3-(ХИНОЛИН-6-ИЛТИО)[1,2,4]ТРИАЗОЛО[4,3-a]ПИРИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ c-MET ТИРОЗИНКИНАЗЫ |
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| AU2003253408A1 (en) | 2002-08-17 | 2004-03-11 | Nycomed Gmbh | Novel phenanthridines |
| CA2495827C (en) * | 2002-08-29 | 2012-05-08 | Altana Pharma Ag | 2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
| AU2005212857B2 (en) | 2004-02-18 | 2011-04-28 | Takeda Gmbh | Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (PDE) 4 inhibitors |
| AR049419A1 (es) | 2004-03-03 | 2006-08-02 | Altana Pharma Ag | Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo |
| CN104803974A (zh) | 2004-03-03 | 2015-07-29 | 塔科达有限责任公司 | 新的羟基-6-杂芳基菲啶及其作为pde4抑制剂的用途 |
| JP2007527899A (ja) | 2004-03-09 | 2007-10-04 | アルタナ ファルマ アクチエンゲゼルシャフト | 新規のイソアミド置換されたヒドロキシ−６−フェニルフェナントリジン |
| CA2558390A1 (en) | 2004-03-10 | 2005-09-22 | Altana Pharma Ag | Novel thio-containing hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors |
| JP2007527901A (ja) | 2004-03-10 | 2007-10-04 | アルタナ ファルマ アクチエンゲゼルシャフト | アミド置換された新規のヒドロキシ−６−フェニルフェナントリジン及びｐｄｅ４インヒビターとしてのそれらの使用 |
| EP1725532A1 (en) | 2004-03-10 | 2006-11-29 | Altana Pharma AG | Novel difluoroethoxy-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors |
| ES2337083T3 (es) | 2005-03-02 | 2010-04-20 | Nycomed Gmbh | (2r,4ar,10br)-6-(2,6-dimetoxipiridin-3-il)-9-exoti-8-metoxi-1,2,3,4,4a,10b-hexahidrofenantridin-2-ol, sal de hc1. |
-
2003
- 2003-08-29 ES ES03757767T patent/ES2281658T3/es not_active Expired - Lifetime
- 2003-08-29 AU AU2003273805A patent/AU2003273805B8/en not_active Ceased
- 2003-08-29 US US10/524,820 patent/US7423046B2/en not_active Expired - Fee Related
- 2003-08-29 EP EP03757767A patent/EP1536798B1/en not_active Expired - Lifetime
- 2003-08-29 DE DE60311662T patent/DE60311662T2/de not_active Expired - Lifetime
- 2003-08-29 AT AT03757767T patent/ATE353217T1/de active
- 2003-08-29 WO PCT/EP2003/009601 patent/WO2004019945A1/en not_active Ceased
- 2003-08-29 JP JP2004532147A patent/JP4587295B2/ja not_active Expired - Fee Related
- 2003-08-29 CA CA2496459A patent/CA2496459C/en not_active Expired - Fee Related
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2008
- 2008-08-27 US US12/230,301 patent/US8202880B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2496459A1 (en) | 2004-03-11 |
| US7423046B2 (en) | 2008-09-09 |
| AU2003273805B8 (en) | 2010-06-17 |
| US8202880B2 (en) | 2012-06-19 |
| ATE353217T1 (de) | 2007-02-15 |
| JP2006508913A (ja) | 2006-03-16 |
| JP4587295B2 (ja) | 2010-11-24 |
| EP1536798A1 (en) | 2005-06-08 |
| ES2281658T3 (es) | 2007-10-01 |
| US20090170892A1 (en) | 2009-07-02 |
| US20050239818A1 (en) | 2005-10-27 |
| AU2003273805A1 (en) | 2004-03-19 |
| WO2004019945A1 (en) | 2004-03-11 |
| EP1536798B1 (en) | 2007-02-07 |
| CA2496459C (en) | 2013-06-25 |
| AU2003273805B2 (en) | 2009-10-01 |
| DE60311662D1 (en) | 2007-03-22 |
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| Date | Code | Title | Description |
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| 8327 | Change in the person/name/address of the patent owner |
Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE |
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| 8364 | No opposition during term of opposition |