DE60310548T2 - Diazabicyclische biarylderivate - Google Patents
Diazabicyclische biarylderivate Download PDFInfo
- Publication number
- DE60310548T2 DE60310548T2 DE60310548T DE60310548T DE60310548T2 DE 60310548 T2 DE60310548 T2 DE 60310548T2 DE 60310548 T DE60310548 T DE 60310548T DE 60310548 T DE60310548 T DE 60310548T DE 60310548 T2 DE60310548 T2 DE 60310548T2
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- Germany
- Prior art keywords
- disorder
- condition
- diazabicyclo
- heptane
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- LYTCVQQGCSNFJU-LKGYBJPKSA-N α-bungarotoxin Chemical compound C(/[C@H]1O[C@H]2C[C@H]3O[C@@H](CC(=C)C=O)C[C@H](O)[C@]3(C)O[C@@H]2C[C@@H]1O[C@@H]1C2)=C/C[C@]1(C)O[C@H]1[C@@]2(C)O[C@]2(C)CC[C@@H]3O[C@@H]4C[C@]5(C)O[C@@H]6C(C)=CC(=O)O[C@H]6C[C@H]5O[C@H]4C[C@@H](C)[C@H]3O[C@H]2C1 LYTCVQQGCSNFJU-LKGYBJPKSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Immunology (AREA)
- Pregnancy & Childbirth (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200200692 | 2002-05-07 | ||
| DK200200692 | 2002-05-07 | ||
| DK200201739 | 2002-11-11 | ||
| DKPA200201739 | 2002-11-11 | ||
| PCT/DK2003/000295 WO2003094831A2 (en) | 2002-05-07 | 2003-05-06 | Novel diazabicyclic biaryl derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60310548D1 DE60310548D1 (de) | 2007-02-01 |
| DE60310548T2 true DE60310548T2 (de) | 2007-05-10 |
Family
ID=29421783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60310548T Expired - Lifetime DE60310548T2 (de) | 2002-05-07 | 2003-05-06 | Diazabicyclische biarylderivate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7300933B2 (enExample) |
| EP (1) | EP1506200B1 (enExample) |
| JP (1) | JP2005524713A (enExample) |
| CN (1) | CN1653068A (enExample) |
| AT (1) | ATE348831T1 (enExample) |
| AU (1) | AU2003223927B2 (enExample) |
| CA (1) | CA2480488A1 (enExample) |
| DE (1) | DE60310548T2 (enExample) |
| DK (1) | DK1506200T3 (enExample) |
| MX (1) | MXPA04010966A (enExample) |
| NZ (1) | NZ535642A (enExample) |
| WO (1) | WO2003094831A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| US7399765B2 (en) | 2003-09-19 | 2008-07-15 | Abbott Laboratories | Substituted diazabicycloalkane derivatives |
| US20050065178A1 (en) * | 2003-09-19 | 2005-03-24 | Anwer Basha | Substituted diazabicycloakane derivatives |
| TW200534855A (en) * | 2004-01-13 | 2005-11-01 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
| US7582631B2 (en) | 2004-01-14 | 2009-09-01 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
| JP2007528420A (ja) * | 2004-03-11 | 2007-10-11 | グラクソ グループ リミテッド | 新規ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト |
| JP2007529511A (ja) * | 2004-03-17 | 2007-10-25 | グラクソ グループ リミテッド | Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト |
| AU2005295441B2 (en) | 2004-10-18 | 2009-04-23 | Amgen, Inc. | Thiadiazole compounds and methods of use |
| JP2008530172A (ja) * | 2005-02-16 | 2008-08-07 | ノイロサーチ アクティーゼルスカブ | ジアザ二環系アリール誘導体及びそれらのニコチン様アセチルコリン受容体におけるコリン作動性リガンドとしての使用 |
| ATE495178T1 (de) | 2005-02-16 | 2011-01-15 | Neurosearch As | Diazabicyclische arylderivate und ihre verwendung als chinolinergische liganden an nikotin- acetylcholin-rezeptoren |
| EP1866314B1 (en) | 2005-02-16 | 2010-09-15 | NeuroSearch A/S | Novel diazabicyclic aryl derivatives and their medical use |
| US7897766B2 (en) * | 2005-09-23 | 2011-03-01 | Abbott Laboratories | Amino-aza-adamantane derivatives and methods of use |
| EP1963323B1 (en) * | 2005-12-06 | 2010-07-14 | Neurosearch A/S | Novel diazabicyclic aryl derivatives and their medical use |
| JO3019B1 (ar) | 2006-04-19 | 2016-09-05 | Janssen Pharmaceutica Nv | ثلاثي مستبدل 4،2،1-ثلاثي زولات |
| US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
| US7897619B2 (en) | 2007-07-17 | 2011-03-01 | Amgen Inc. | Heterocyclic modulators of PKB |
| AU2008276512A1 (en) | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of PKB |
| JO2784B1 (en) * | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
| JP2011500625A (ja) * | 2007-10-18 | 2011-01-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | トリ置換された１，２，４−トリアゾール |
| NZ587669A (en) | 2008-03-19 | 2011-07-29 | Janssen Pharmaceutica Nv | Trisubstituted 1, 2, 4 -triazoles as nicotinic acetylcholine receptor modulators |
| EP2280945B1 (en) | 2008-05-09 | 2014-09-03 | Janssen Pharmaceutica, N.V. | Trisubstituted pyrazoles as acetylcholine receptor modulators |
| BR112012013765A2 (pt) * | 2009-12-07 | 2016-04-26 | Targacept Inc | 3,6-diazabiciclo[3.1.1] heptanos como ligantes de receptor nicotínico neuronal de acetilcolina |
| CN103221411B (zh) | 2010-05-17 | 2016-05-11 | 富瑞姆制药公司 | (R)-7-氯-N-(奎宁环-3-基)苯并[b]噻吩-2-甲酰胺盐酸盐单水合物的晶型 |
| CN106074548A (zh) | 2010-09-23 | 2016-11-09 | 艾伯维巴哈马有限公司 | 氮杂金刚烷衍生物的一水合物 |
| AU2013259871A1 (en) | 2012-05-08 | 2014-11-20 | Forum Pharmaceuticals Inc. | Methods of maintaining, treating or improving cognitive function |
| US9040712B2 (en) * | 2013-01-23 | 2015-05-26 | Novartis Ag | Thiadiazole analogs thereof and methods for treating SMN-deficiency-related-conditions |
| WO2015065004A1 (ko) * | 2013-10-29 | 2015-05-07 | 주식회사 엘지화학 | 겔 폴리머 전해질 및 이를 포함하는 리튬 이차전지 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| FR2786769B1 (fr) | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
| DE60006213T2 (de) * | 1999-01-29 | 2004-07-29 | Abbott Laboratories, Abbott Park | Diazabicyloderivate als nikotin-acetylcholin-rezeptorliganden |
| US6852721B2 (en) * | 2000-05-25 | 2005-02-08 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
-
2003
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- 2003-05-06 CN CNA03810198XA patent/CN1653068A/zh active Pending
- 2003-05-06 AU AU2003223927A patent/AU2003223927B2/en not_active Ceased
- 2003-05-06 NZ NZ535642A patent/NZ535642A/en not_active IP Right Cessation
- 2003-05-06 DE DE60310548T patent/DE60310548T2/de not_active Expired - Lifetime
- 2003-05-06 EP EP03720288A patent/EP1506200B1/en not_active Expired - Lifetime
- 2003-05-06 JP JP2004502920A patent/JP2005524713A/ja active Pending
- 2003-05-06 AT AT03720288T patent/ATE348831T1/de not_active IP Right Cessation
- 2003-05-06 DK DK03720288T patent/DK1506200T3/da active
- 2003-05-06 CA CA002480488A patent/CA2480488A1/en not_active Abandoned
- 2003-05-06 US US10/513,398 patent/US7300933B2/en not_active Expired - Fee Related
- 2003-05-06 MX MXPA04010966A patent/MXPA04010966A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN1653068A (zh) | 2005-08-10 |
| EP1506200A2 (en) | 2005-02-16 |
| US7300933B2 (en) | 2007-11-27 |
| AU2003223927B2 (en) | 2009-12-17 |
| WO2003094831A2 (en) | 2003-11-20 |
| AU2003223927A1 (en) | 2003-11-11 |
| DK1506200T3 (da) | 2007-04-10 |
| MXPA04010966A (es) | 2005-01-25 |
| DE60310548D1 (de) | 2007-02-01 |
| EP1506200B1 (en) | 2006-12-20 |
| US20050131236A1 (en) | 2005-06-16 |
| WO2003094831A3 (en) | 2004-01-15 |
| CA2480488A1 (en) | 2003-11-20 |
| ATE348831T1 (de) | 2007-01-15 |
| NZ535642A (en) | 2006-10-27 |
| JP2005524713A (ja) | 2005-08-18 |
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