DE60223696T2 - Massenmarker - Google Patents
Massenmarker Download PDFInfo
- Publication number
- DE60223696T2 DE60223696T2 DE60223696T DE60223696T DE60223696T2 DE 60223696 T2 DE60223696 T2 DE 60223696T2 DE 60223696 T DE60223696 T DE 60223696T DE 60223696 T DE60223696 T DE 60223696T DE 60223696 T2 DE60223696 T2 DE 60223696T2
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- Germany
- Prior art keywords
- mass
- marker
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- markers
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
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- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
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- Investigating Or Analysing Biological Materials (AREA)
- Indole Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US20040219685A1 (en) | 2003-01-30 | 2004-11-04 | Applera Corporation | Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents |
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| US7105806B2 (en) | 2003-11-26 | 2006-09-12 | Applera Corporation | Method and apparatus for de-convoluting a convoluted spectrum |
| EP1916527A1 (en) * | 2003-11-26 | 2008-04-30 | Applera Corporation | Analysis of mass spectral data in the quiet zones |
| US7307169B2 (en) | 2004-01-05 | 2007-12-11 | Applera Corporation | Isotopically enriched N-substituted piperazines and methods for the preparation thereof |
| US7355045B2 (en) | 2004-01-05 | 2008-04-08 | Applera Corporation | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof |
| WO2005076009A2 (en) * | 2004-01-28 | 2005-08-18 | Immatics Biotechnologies Gmbh | Method for identifying and quantifying of tumour-associated peptides |
| US20080206737A1 (en) * | 2004-05-19 | 2008-08-28 | Hunter Christie L | Expression quantification using mass spectrometry |
| US20070054345A1 (en) * | 2004-05-19 | 2007-03-08 | Hunter Christie L | Expression quantification using mass spectrometry |
| EP1756307A1 (en) * | 2004-05-20 | 2007-02-28 | Trillion Genomics Limited | Use of mass labelled probes to detect target nucleic acids using mass spectrometry |
| US20070048752A1 (en) | 2004-07-12 | 2007-03-01 | Applera Corporation | Mass tags for quantitative analyses |
| WO2006017208A1 (en) * | 2004-07-12 | 2006-02-16 | Applera Corporation | Mass tags for quantitative analyses |
| WO2006023398A2 (en) * | 2004-08-16 | 2006-03-02 | Ludwig Institute For Cancer Research | Modular isotope labelled mass spectrometry reagents and methods for quantitation of amino acids, peptides and proteins |
| US20060134710A1 (en) * | 2004-10-30 | 2006-06-22 | Viorica Lopez-Avila | WDR11 protein assay |
| CA2596117A1 (en) * | 2005-02-03 | 2006-08-10 | Perkinelmer Las, Inc. | Ultra-sensitive detection systems using multidimension signals |
| US20060183238A1 (en) | 2005-02-09 | 2006-08-17 | Applera Corporation | Amine-containing compound analysis methods |
| US20070134802A1 (en) * | 2005-06-30 | 2007-06-14 | Heinz Doebeli | Ionization modifier for mass spectrometry |
| GB0515323D0 (en) | 2005-07-26 | 2005-08-31 | Electrophoretics Ltd | Mass labels |
| US8889423B2 (en) | 2005-07-29 | 2014-11-18 | Eisai R & D Management Co., Ltd. | Method for analysis of compound-binding ability of protein |
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| EP1921081A1 (en) * | 2006-11-06 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Use of arylboronic acids in protein labelling |
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| US20100311176A1 (en) * | 2007-05-23 | 2010-12-09 | Applied Biosystems, Llc | Method of mass analysis of target molecules in complex mixtures |
| GB0809488D0 (en) | 2008-05-23 | 2008-07-02 | Electrophoretics Ltd | Mass spectrometric analysis |
| GB0811574D0 (en) * | 2008-06-24 | 2008-07-30 | Trillion Genomics Ltd | Characterising planar samples by mass spectrometry |
| KR101081053B1 (ko) * | 2008-07-18 | 2011-11-07 | 포항공과대학교 산학협력단 | 가변질량 라벨링제와 이를 이용한 아미노산 서열 및 단백질정량 동시 분석방법 |
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| GB0921665D0 (en) | 2009-12-10 | 2010-01-27 | Trillion Genomics Ltd | Phobes |
| JP5730908B2 (ja) * | 2010-01-25 | 2015-06-10 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | ビタミンｄ３、ビタミンｄ２、およびこれらの代謝体の定量分析 |
| US8455818B2 (en) | 2010-04-14 | 2013-06-04 | Wisconsin Alumni Research Foundation | Mass spectrometry data acquisition mode for obtaining more reliable protein quantitation |
| GB201006360D0 (en) | 2010-04-16 | 2010-06-02 | Immatics Biotechnologies Gmbh | Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development |
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| US8589084B2 (en) * | 2010-10-08 | 2013-11-19 | Massachusetts Institute Of Technology | Detection of ethanol emission from a spark ignition engine operating on gasohols |
| US20140017797A1 (en) * | 2010-12-13 | 2014-01-16 | De Staadt der Nederlanden, vert doorde minister van VWS | Protein affinity tag and uses thereof |
| DE102012102875B4 (de) | 2011-04-04 | 2024-04-18 | Wisconsin Alumni Research Foundation | Vorläuferauswahl mit einem Artificial-Intelligence-Algorithmus erhöht Abdeckung und Reproduzierbarkeit von proteomischen Proben |
| US9388132B2 (en) | 2011-09-15 | 2016-07-12 | Wisconsin Alumni Research Foundation | Isobaric tandem mass tags for quantitative proteomics and peptidomics |
| US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| WO2013170067A1 (en) | 2012-05-10 | 2013-11-14 | Thermo Finnigan Llc | Method for highly multiplexed quantitation of peptides by mass spectrometry and labeling reagent sets therefor |
| EP2852678B1 (en) * | 2012-05-22 | 2017-08-23 | Biogen MA Inc. | Trapping reagents for reactive metabolites screening |
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| US10269550B2 (en) | 2014-02-21 | 2019-04-23 | Purdue Research Foundation | Systems and methods for quantifying an analyte extracted from a sample |
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| GB201423361D0 (en) | 2014-12-30 | 2015-02-11 | Immatics Biotechnologies Gmbh | Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides |
| US11061023B2 (en) | 2016-06-21 | 2021-07-13 | Waters Technologies Corporation | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals |
| WO2017222955A1 (en) | 2016-06-21 | 2017-12-28 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
| EP3479103B1 (en) | 2016-07-01 | 2022-04-20 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
| CN110609103A (zh) * | 2018-06-15 | 2019-12-24 | 中国科学院大连化学物理研究所 | 基于化学标记和质谱的蛋白与材料相互作用结构分析方法 |
| KR102362170B1 (ko) * | 2019-04-08 | 2022-02-11 | 주식회사 엘지화학 | Maldi 질량분석을 이용한 고분자의 상대적 정량분석방법 |
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| US5258498A (en) * | 1987-05-21 | 1993-11-02 | Creative Biomolecules, Inc. | Polypeptide linkers for production of biosynthetic proteins |
| GB9315847D0 (en) * | 1993-07-30 | 1993-09-15 | Isis Innovation | Tag reagent and assay method |
| DE69701671T3 (de) * | 1996-01-23 | 2006-08-17 | Qiagen Genomics, Inc., Bothell | Verfahren und zusammenstellungen zur sequenzbestimmung von nukleinsäuremolekülen |
| US6027890A (en) * | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
| ES2213823T3 (es) | 1996-04-08 | 2004-09-01 | Glaxo Group Limited | Codificacion y analisis cualitativo de bibliotecas combinatorias basadas en masa. |
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| CA2303790A1 (en) | 1997-09-15 | 1999-03-25 | Brax Group Limited | Characterising nucleic acid by mass spectrometry |
| GB9823646D0 (en) | 1997-12-19 | 1998-12-23 | Brax Genomics Ltd | Compounds for mass spectrometry |
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| CA2419159A1 (en) | 2000-08-11 | 2002-02-21 | Agilix Corporation | Ultra-sensitive detection systems |
-
2002
- 2002-09-16 PT PT02767650T patent/PT1425586E/pt unknown
- 2002-09-16 JP JP2003529154A patent/JP4290003B2/ja not_active Expired - Lifetime
- 2002-09-16 WO PCT/GB2002/004240 patent/WO2003025576A2/en not_active Ceased
- 2002-09-16 DK DK02767650T patent/DK1425586T3/da active
- 2002-09-16 DE DE60223696T patent/DE60223696T2/de not_active Expired - Lifetime
- 2002-09-16 US US10/489,341 patent/US7732378B2/en not_active Expired - Lifetime
- 2002-09-16 ES ES02767650T patent/ES2296996T3/es not_active Expired - Lifetime
- 2002-09-16 EP EP02767650A patent/EP1425586B1/en not_active Expired - Lifetime
- 2002-09-16 CA CA002460131A patent/CA2460131C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1425586T3 (da) | 2008-02-11 |
| EP1425586B1 (en) | 2007-11-21 |
| CA2460131A1 (en) | 2003-03-27 |
| WO2003025576A3 (en) | 2003-07-31 |
| JP4290003B2 (ja) | 2009-07-01 |
| CA2460131C (en) | 2006-11-21 |
| WO2003025576A2 (en) | 2003-03-27 |
| PT1425586E (pt) | 2007-12-31 |
| US7732378B2 (en) | 2010-06-08 |
| US20050048489A1 (en) | 2005-03-03 |
| ES2296996T3 (es) | 2008-05-01 |
| DE60223696D1 (de) | 2008-01-03 |
| JP2005503557A (ja) | 2005-02-03 |
| EP1425586A2 (en) | 2004-06-09 |
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