DE60214150D1 - Multiformat-probenprozessierungsvorrichtungen, -verfahren und -systeme - Google Patents
Multiformat-probenprozessierungsvorrichtungen, -verfahren und -systemeInfo
- Publication number
- DE60214150D1 DE60214150D1 DE60214150T DE60214150T DE60214150D1 DE 60214150 D1 DE60214150 D1 DE 60214150D1 DE 60214150 T DE60214150 T DE 60214150T DE 60214150 T DE60214150 T DE 60214150T DE 60214150 D1 DE60214150 D1 DE 60214150D1
- Authority
- DE
- Germany
- Prior art keywords
- sample processing
- multiformat
- processes
- systems
- processing devices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/147—Employing temperature sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1861—Means for temperature control using radiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1861—Means for temperature control using radiation
- B01L2300/1872—Infrared light
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F27—FURNACES; KILNS; OVENS; RETORTS
- F27B—FURNACES, KILNS, OVENS, OR RETORTS IN GENERAL; OPEN SINTERING OR LIKE APPARATUS
- F27B9/00—Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity
- F27B9/14—Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity characterised by the path of the charge during treatment; characterised by the means by which the charge is moved during treatment
- F27B9/16—Furnaces through which the charge is moved mechanically, e.g. of tunnel type; Similar furnaces in which the charge moves by gravity characterised by the path of the charge during treatment; characterised by the means by which the charge is moved during treatment the charge moving in a circular or arcuate path
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F27—FURNACES; KILNS; OVENS; RETORTS
- F27D—DETAILS OR ACCESSORIES OF FURNACES, KILNS, OVENS, OR RETORTS, IN SO FAR AS THEY ARE OF KINDS OCCURRING IN MORE THAN ONE KIND OF FURNACE
- F27D5/00—Supports, screens, or the like for the charge within the furnace
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/111666—Utilizing a centrifuge or compartmented rotor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/115831—Condition or time responsive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Design And Manufacture Of Integrated Circuits (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US837073 | 2001-04-18 | ||
US09/837,073 US6720187B2 (en) | 2000-06-28 | 2001-04-18 | Multi-format sample processing devices |
PCT/US2002/007663 WO2002086454A1 (en) | 2001-04-18 | 2002-03-12 | Multi-format sample processing devices, methods and systems |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60214150D1 true DE60214150D1 (de) | 2006-10-05 |
DE60214150T2 DE60214150T2 (de) | 2007-08-23 |
Family
ID=25273440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60214150T Expired - Lifetime DE60214150T2 (de) | 2001-04-18 | 2002-03-12 | Multiformat-probenprozessierungsvorrichtungen, -verfahren und -systeme |
Country Status (7)
Country | Link |
---|---|
US (2) | US6720187B2 (de) |
EP (2) | EP1729105A1 (de) |
JP (1) | JP4205434B2 (de) |
AT (1) | ATE337544T1 (de) |
CA (1) | CA2443511A1 (de) |
DE (1) | DE60214150T2 (de) |
WO (1) | WO2002086454A1 (de) |
Families Citing this family (130)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US6720187B2 (en) | 2000-06-28 | 2004-04-13 | 3M Innovative Properties Company | Multi-format sample processing devices |
US6734401B2 (en) * | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
GB2368809B (en) * | 2000-09-15 | 2004-09-29 | Norchip As | Microfabricated reaction chamber system |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US6514750B2 (en) | 2001-07-03 | 2003-02-04 | Pe Corporation (Ny) | PCR sample handling device |
KR100488281B1 (ko) | 2001-09-15 | 2005-05-10 | 아람 바이오시스템 주식회사 | 열 대류를 이용한 염기서열 증폭 방법 및 장치 |
US7192560B2 (en) * | 2001-12-20 | 2007-03-20 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using anion exchange |
US7347976B2 (en) * | 2001-12-20 | 2008-03-25 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix |
US6889468B2 (en) * | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
JP2005532043A (ja) * | 2002-04-11 | 2005-10-27 | シークエノム, インコーポレイテッド | 固相支持体上で化学反応を実行するための方法および装置 |
US7452712B2 (en) | 2002-07-30 | 2008-11-18 | Applied Biosystems Inc. | Sample block apparatus and method of maintaining a microcard on a sample block |
US7169602B2 (en) * | 2002-12-04 | 2007-01-30 | Applera Corporation | Sample substrate for use in biological testing and method for filling a sample substrate |
US7332129B2 (en) * | 2003-01-09 | 2008-02-19 | 3M Innovative Properties Company | Sample processing device having process chambers with bypass slots |
JP2004305009A (ja) * | 2003-04-02 | 2004-11-04 | Hitachi Ltd | 核酸増幅装置及び核酸増幅方法 |
US7981600B2 (en) * | 2003-04-17 | 2011-07-19 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene |
US20050026273A1 (en) * | 2003-06-05 | 2005-02-03 | Zarur Andrey J. | Reactor with memory component |
US20040258563A1 (en) * | 2003-06-23 | 2004-12-23 | Applera Corporation | Caps for sample wells and microcards for biological materials |
JP4695851B2 (ja) * | 2003-07-10 | 2011-06-08 | シチズンホールディングス株式会社 | マイクロ化学チップ温度調節装置 |
US7731906B2 (en) | 2003-07-31 | 2010-06-08 | Handylab, Inc. | Processing particle-containing samples |
WO2005038041A2 (en) * | 2003-10-16 | 2005-04-28 | Third Wave Technologies, Inc. | Direct nucleic acid detection in bodily fluids |
US7322254B2 (en) * | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US20050130177A1 (en) * | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7727710B2 (en) * | 2003-12-24 | 2010-06-01 | 3M Innovative Properties Company | Materials, methods, and kits for reducing nonspecific binding of molecules to a surface |
US7939249B2 (en) * | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
WO2005066372A2 (en) * | 2003-12-31 | 2005-07-21 | Applera Corporation | Quantitative amplification and detection of small numbers of target polynucleotides |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
AU2005241080B2 (en) * | 2004-05-03 | 2011-08-11 | Handylab, Inc. | Processing polynucleotide-containing samples |
US20090317897A1 (en) * | 2004-05-27 | 2009-12-24 | Universal Bio Research Co., Ltd. | Reaction vessel, reaction measuring device, and liquid rotating treatment device |
CN100565207C (zh) | 2004-10-01 | 2009-12-02 | 株式会社日立高新技术 | 化学分析装置 |
JP2008518621A (ja) * | 2004-11-03 | 2008-06-05 | サード・ウェーブ・テクノロジーズ・インク | 一段階検出アッセイ法 |
US20060252032A1 (en) * | 2005-01-28 | 2006-11-09 | Third Wave Technologies, Inc. | Detection of human herpesviruses |
US7323660B2 (en) | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
US7763210B2 (en) * | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
KR100691806B1 (ko) * | 2005-08-04 | 2007-03-12 | 삼성전자주식회사 | 비드 및 나노포어를 이용한 핵산 검출방법 및 검출장치 |
US20080014124A1 (en) * | 2005-08-04 | 2008-01-17 | Third Wave Technologies, Inc. | Sample processing devices, systems and methods |
WO2007035350A2 (en) * | 2005-09-15 | 2007-03-29 | University Of Utah Research Foundation | Bioluminescence-based sensor with centrifugal separation and enhanced light collection |
US20070184547A1 (en) * | 2005-10-11 | 2007-08-09 | Kalyan Handique | Polynucleotide sample preparation device |
US8822206B2 (en) * | 2005-10-11 | 2014-09-02 | The Johns Hopkins University | Device for high-throughput stimulation, immunostaining, and visualization of single cells |
WO2007044888A2 (en) * | 2005-10-11 | 2007-04-19 | The Johns Hopkins Univerisity | Microfluidic device and method for high-throughput cellular gradient and dose response studies |
WO2007044974A2 (en) * | 2005-10-12 | 2007-04-19 | The Research Foundation Of State University Of New York | Absolute pcr quantification |
KR100730350B1 (ko) * | 2005-10-17 | 2007-06-19 | 삼성전자주식회사 | 표면처리된 나노포어를 이용한 dna 검출방법 및검출장치 |
US7482127B2 (en) * | 2005-11-03 | 2009-01-27 | Third Wave Technologies, Inc. | Nucleic acid detection assays employing blocker oligonucleotides |
US20080181823A1 (en) * | 2005-11-08 | 2008-07-31 | Third Wave Technologies, Inc. | Plate spinner systems and devices |
TWI386484B (zh) * | 2005-11-24 | 2013-02-21 | Universal Bio Research Co Ltd | 反應容器、反應測量裝置、及液體旋轉處理裝置 |
US20100028211A1 (en) * | 2006-02-07 | 2010-02-04 | Eppendorf Ag | Cover sheet for a microtiter plate |
US8883490B2 (en) * | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US8088616B2 (en) | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
JP5415253B2 (ja) | 2006-03-24 | 2014-02-12 | ハンディラブ・インコーポレーテッド | 微小流体サンプルを処理するための一体化システム及びその使用方法 |
US7998708B2 (en) * | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US20080131875A1 (en) * | 2006-06-07 | 2008-06-05 | Third Wave Technologies, Inc. | Multiplex assays |
US7759062B2 (en) * | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
US7629124B2 (en) * | 2006-06-30 | 2009-12-08 | Canon U.S. Life Sciences, Inc. | Real-time PCR in micro-channels |
EP2079754B1 (de) | 2006-10-04 | 2017-03-15 | Third Wave Technologies, Inc. | Snap-back primer und nachweisbare hairpin-strukturen |
US8709787B2 (en) * | 2006-11-14 | 2014-04-29 | Handylab, Inc. | Microfluidic cartridge and method of using same |
CA2673056A1 (en) * | 2006-12-22 | 2008-07-03 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
CN101568385B (zh) | 2006-12-22 | 2012-08-15 | 3M创新有限公司 | 用于微流体系统的热转移方法和结构 |
US20110020947A1 (en) * | 2007-04-25 | 2011-01-27 | 3M Innovative Properties Company | Chemical component and processing device assembly |
WO2008134470A2 (en) * | 2007-04-25 | 2008-11-06 | 3M Innovative Properties Company | Methods for nucleic acid amplification |
US8835157B2 (en) * | 2007-04-25 | 2014-09-16 | 3M Innovative Properties Company | Supported reagents, methods, and devices |
WO2008134472A1 (en) * | 2007-04-25 | 2008-11-06 | 3M Innovative Properties Company | Compositions, methods, and devices for isolating biological materials |
US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
CA2693654C (en) | 2007-07-13 | 2018-02-13 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
JP4614992B2 (ja) * | 2007-07-27 | 2011-01-19 | パナソニック株式会社 | 分析用デバイスとこれを使用する分析装置および分析方法 |
EP2188387A1 (de) * | 2007-08-13 | 2010-05-26 | 3M Innovative Properties Company | Verfahren für den nachweis wirkstoffresistenter mikroben |
CA2700532A1 (en) | 2007-09-28 | 2009-04-02 | 3M Innovative Properties Company | Dual oligonucleotide method of nucleic acid detection |
US20100209927A1 (en) * | 2007-11-06 | 2010-08-19 | Menon Vinod P | Processing device tablet |
ATE541639T1 (de) * | 2007-11-24 | 2012-02-15 | Hoffmann La Roche | Analysesystem und verfahren zur analyse einer körperflüssigkeitsprobe auf einen darin enthaltenen analyten |
DE102007063102B4 (de) * | 2007-12-28 | 2022-02-10 | Robert Bosch Gmbh | Verfahren zur Erfassung eines periodisch pulsierenden Betriebsparameters |
US20110183398A1 (en) * | 2007-12-31 | 2011-07-28 | 3M Innovative Properties | Microorganism-capturing compositions and methods |
USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
US20100009351A1 (en) * | 2008-07-11 | 2010-01-14 | Handylab, Inc. | Polynucleotide Capture Materials, and Method of Using Same |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
US8647508B2 (en) | 2008-12-19 | 2014-02-11 | 3M Innovative Properties Company | System and method for processing samples |
US8535945B2 (en) | 2008-12-19 | 2013-09-17 | 3M Innovative Properties Company | System and method for concentrating samples |
US10196700B2 (en) | 2009-03-24 | 2019-02-05 | University Of Chicago | Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes |
US9447461B2 (en) | 2009-03-24 | 2016-09-20 | California Institute Of Technology | Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes |
US9415392B2 (en) | 2009-03-24 | 2016-08-16 | The University Of Chicago | Slip chip device and methods |
US9464319B2 (en) | 2009-03-24 | 2016-10-11 | California Institute Of Technology | Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes |
US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
USD638951S1 (en) | 2009-11-13 | 2011-05-31 | 3M Innovative Properties Company | Sample processing disk cover |
USD638550S1 (en) | 2009-11-13 | 2011-05-24 | 3M Innovative Properties Company | Sample processing disk cover |
USD667561S1 (en) | 2009-11-13 | 2012-09-18 | 3M Innovative Properties Company | Sample processing disk cover |
US20110117607A1 (en) * | 2009-11-13 | 2011-05-19 | 3M Innovative Properties Company | Annular compression systems and methods for sample processing devices |
CN102791847B (zh) | 2010-01-12 | 2015-01-21 | 阿赫姆生物系统公司 | 三阶段热对流装置及其用途 |
KR102032523B1 (ko) | 2010-01-12 | 2019-10-15 | 아람 바이오시스템 주식회사 | 2단 열대류 장치 및 그 사용법 |
WO2011127386A2 (en) | 2010-04-09 | 2011-10-13 | Life Technologies Corporation | Improved thermal uniformity for thermal cycler instrumentation using dynamic control |
US9221055B2 (en) * | 2010-11-08 | 2015-12-29 | Hitachi High-Technologies Corporation | Reaction plate assembly, reaction plate and nucleic acid analysis device |
JP2012103019A (ja) * | 2010-11-08 | 2012-05-31 | Hitachi High-Technologies Corp | 反応プレートアセンブリ、反応プレート及び核酸分析装置 |
JP5593205B2 (ja) * | 2010-11-08 | 2014-09-17 | 株式会社日立ハイテクノロジーズ | 核酸分析装置 |
US9562262B2 (en) | 2011-03-08 | 2017-02-07 | UNIVERSITé LAVAL | Fluidic centripetal device |
JP2012187054A (ja) * | 2011-03-11 | 2012-10-04 | Hitachi High-Technologies Corp | 核酸増幅反応装置 |
EP3159697B1 (de) | 2011-04-15 | 2019-12-25 | Becton, Dickinson and Company | Mikrofluidischer echtzeit-abtastender thermocycler |
AU2012255142B2 (en) * | 2011-05-18 | 2015-03-05 | Diasorin Italia S.P.A. | Systems and methods for valving on a sample processing device |
ES2870874T3 (es) | 2011-05-18 | 2021-10-27 | Diasorin S P A | Sistemas y métodos para detectar la presencia de un volumen seleccionado de material en un dispositivo de procesamiento de muestra |
KR20140022399A (ko) | 2011-05-18 | 2014-02-24 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 샘플 처리 장치 상의 체적 계량을 위한 시스템 및 방법 |
USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
JP2013000012A (ja) * | 2011-06-14 | 2013-01-07 | Hitachi High-Technologies Corp | 反応デバイス及びこれを用いた反応装置 |
WO2013003308A1 (en) | 2011-06-30 | 2013-01-03 | 3M Innovative Properties Company | Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces |
EP2726843B1 (de) | 2011-06-30 | 2016-03-02 | 3M Innovative Properties Company | Systeme und verfahren zum nachweis eines bestimmten analyten in einer probe unter verwendung von filtern und mikrostrukturierten oberflächen |
ES2825905T3 (es) | 2011-09-30 | 2021-05-17 | Becton Dickinson Co | Tira reactiva unificada |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
EP2773892B1 (de) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Vorrichtung zur vorbereitung von polynukleotidproben |
KR20130086743A (ko) * | 2012-01-26 | 2013-08-05 | 삼성전자주식회사 | 미세유동장치 및 그 제어방법 |
CA2863637C (en) | 2012-02-03 | 2021-10-26 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
CN105813754B (zh) * | 2013-09-16 | 2018-12-14 | 生命科技股份有限公司 | 用于向热循环仪提供热均匀性的设备、系统和方法 |
WO2015126621A1 (en) | 2014-02-18 | 2015-08-27 | Life Technologies Corporation | Apparatuses, systems and methods for providing scalable thermal cyclers and isolating thermoelectric devices |
USD799715S1 (en) | 2015-10-23 | 2017-10-10 | Gene POC, Inc. | Fluidic centripetal device |
EP3426399B1 (de) * | 2016-03-10 | 2021-03-10 | Pioneer Hi-Bred International, Inc. | Lichtvermittelte polymerasekettenreaktionsamplifikation und produktdetektionssystem sowie verfahren zur verwendung |
JP6421159B2 (ja) | 2016-10-28 | 2018-11-07 | シスメックス株式会社 | 液体封止カートリッジおよび送液方法 |
CN107739706B (zh) * | 2017-09-26 | 2020-04-14 | 南京岚煜生物科技有限公司 | 主动控制流路的多通量微流控核酸检测芯片及其使用方法 |
PL425107A1 (pl) * | 2018-03-30 | 2019-10-07 | Bacteromic Spółka Z Ograniczoną Odpowiedzialnością | Segment inkubacyjny |
CN209974747U (zh) | 2019-04-09 | 2020-01-21 | 北京京东方技术开发有限公司 | 用于检测芯片的反应设备及反应系统 |
JP7445403B2 (ja) | 2019-09-27 | 2024-03-07 | シスメックス株式会社 | 液体封止カートリッジおよび送液方法 |
CN113583799A (zh) * | 2020-04-30 | 2021-11-02 | 京东方科技集团股份有限公司 | 用于检测芯片的分析装置及其操作方法、分析系统 |
Family Cites Families (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3555284A (en) | 1968-12-18 | 1971-01-12 | Norman G Anderson | Multistation, single channel analytical photometer and method of use |
GB1413987A (en) | 1972-03-15 | 1975-11-12 | Hall Thermotank Int Ltd | Heat exchangers |
US3798459A (en) | 1972-10-06 | 1974-03-19 | Atomic Energy Commission | Compact dynamic multistation photometer utilizing disposable cuvette rotor |
US3795451A (en) | 1973-04-24 | 1974-03-05 | Atomic Energy Commission | Rotor for fast analyzer of rotary cuvette type |
US3873217A (en) | 1973-07-24 | 1975-03-25 | Atomic Energy Commission | Simplified rotor for fast analyzer of rotary cuvette type |
US4030834A (en) | 1976-04-08 | 1977-06-21 | The United States Of America As Represented By The United States Energy Research And Development Administration | Dynamic multistation photometer |
IT1097442B (it) | 1977-08-18 | 1985-08-31 | Guigan Jean | Dispositivo di condizionamento di un campione di liquido in preparazione della sua analisi |
US4284602A (en) | 1979-12-10 | 1981-08-18 | Immutron, Inc. | Integrated fluid manipulator |
US4396579A (en) | 1981-08-06 | 1983-08-02 | Miles Laboratories, Inc. | Luminescence detection device |
US5496520A (en) | 1982-01-08 | 1996-03-05 | Kelton; Arden A. | Rotary fluid manipulator |
US4632908A (en) | 1984-05-03 | 1986-12-30 | Abbott Laboratories | Heating system for rotating members |
US4580898A (en) | 1984-05-31 | 1986-04-08 | Allied Corporation | Analytical system |
US5214119A (en) | 1986-06-20 | 1993-05-25 | Minnesota Mining And Manufacturing Company | Block copolymer, method of making the same, dimaine precursors of the same, method of making such diamines and end products comprising the block copolymer |
JPS6319558A (ja) | 1986-07-11 | 1988-01-27 | Konica Corp | 血液検査方法及び装置 |
DE3712624A1 (de) | 1987-04-14 | 1988-11-03 | Holzer Walter | Kleinzentrifuge |
US4906432B1 (en) | 1987-07-17 | 1991-06-25 | Liquid handling | |
JPS6441861A (en) | 1987-08-07 | 1989-02-14 | Shimadzu Corp | Sample distribution |
JP2502132B2 (ja) | 1988-09-30 | 1996-05-29 | 三菱重工業株式会社 | 形状記憶ポリウレタンエラストマ―成形体 |
JPH0739506B2 (ja) | 1988-09-30 | 1995-05-01 | 三菱重工業株式会社 | 形状記憶ポリマー発泡体 |
JPH066342B2 (ja) | 1988-10-14 | 1994-01-26 | 三菱重工業株式会社 | 形状記憶性フィルム及びその使用法 |
US5135786A (en) | 1988-10-14 | 1992-08-04 | Mitsubishi Jukogyo Kabushiki Kaisha | Shape memory Transparent body and method of using the same |
JPH0723572B2 (ja) | 1988-10-17 | 1995-03-15 | 三菱重工業株式会社 | 形状記憶性ポリマーによる織布 |
CA2011740A1 (en) | 1989-04-07 | 1990-10-07 | Glen Connell | Microwave heatable materials |
JPH02292720A (ja) | 1989-05-01 | 1990-12-04 | Jiro Tanaka | 磁気カード |
JPH0348770A (ja) | 1989-07-18 | 1991-03-01 | Fuji Photo Film Co Ltd | 生化学分析装置 |
JPH05507878A (ja) | 1990-06-15 | 1993-11-11 | カイロン コーポレイション | 組込みアッセイアセンブリおよび装置 |
KR100236506B1 (ko) | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
AU656556B2 (en) | 1991-03-13 | 1995-02-09 | Minnesota Mining And Manufacturing Company | Radio frequency induction heatable compositions |
JP3194601B2 (ja) | 1991-10-02 | 2001-07-30 | オリンパス光学工業株式会社 | 自動分析方法および自動分析装置 |
US5278377A (en) | 1991-11-27 | 1994-01-11 | Minnesota Mining And Manufacturing Company | Electromagnetic radiation susceptor material employing ferromagnetic amorphous alloy particles |
FI915731A0 (fi) | 1991-12-05 | 1991-12-05 | Derek Henry Potter | Foerfarande och anordning foer reglering av temperaturen i ett flertal prov. |
US5637469A (en) * | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
JP3024375B2 (ja) | 1992-07-31 | 2000-03-21 | 味の素株式会社 | 自動前処理装置 |
DE4227830C1 (de) | 1992-08-21 | 1994-03-31 | Tulaszewski Olaf | Verfahren und Einrichtung zum Desinfizieren eines Knochentransplantats, insbesondere eines humanen Spongiosa-Transplantats |
JP3305322B2 (ja) | 1992-11-06 | 2002-07-22 | バイオログ,インコーポレーテッド | 液体及び懸濁液の分析装置 |
CA2119286A1 (en) | 1993-04-15 | 1994-10-16 | Hubert S. Smith, Iii | Internally lubricated elastomers for use in biomedical applications |
SE501380C2 (sv) | 1993-06-15 | 1995-01-30 | Pharmacia Lkb Biotech | Sätt att tillverka mikrokanal/mikrokavitetsstrukturer |
ATE208658T1 (de) | 1993-07-28 | 2001-11-15 | Pe Corp Ny | Vorrichtung und verfahren zur nukleinsäurevervielfältigung |
CA2130013C (en) | 1993-09-10 | 1999-03-30 | Rolf Moser | Apparatus for automatic performance of temperature cycles |
JPH09508224A (ja) | 1994-01-11 | 1997-08-19 | アボツト・ラボラトリーズ | 熱サイクル核酸検定の装置および方法 |
US5639428A (en) | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
US5461135A (en) | 1994-09-23 | 1995-10-24 | Olin Corporation | Polyisocyanates containing uretidione and allophanate groups, a process for their production, and their use in one and two component coating compositions |
US5571410A (en) * | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
US5585069A (en) | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
AU4998296A (en) | 1995-03-29 | 1996-10-16 | Minnesota Mining And Manufacturing Company | Electromagnetic-power-absorbing composite |
WO1996035458A2 (en) | 1995-04-25 | 1996-11-14 | Minnesota Mining And Manufacturing Company | Tackified polydiorganosiloxane polyurea segmented copolymers and a process for making same |
CA2219787A1 (en) | 1995-04-25 | 1996-10-31 | Mieczyslaw H. Mazurek | Polydiorganosiloxane polyurea segmented copolymers and a process for making same |
WO1996034028A1 (en) | 1995-04-25 | 1996-10-31 | Minnesota Mining And Manufacturing Company | Tackified polydiorganosiloxane oligourea segmented copolymers and a process for making same |
US5604130A (en) | 1995-05-31 | 1997-02-18 | Chiron Corporation | Releasable multiwell plate cover |
WO1996041864A1 (en) | 1995-06-13 | 1996-12-27 | The Regents Of The University Of California | Diode laser heated micro-reaction chamber with sample detection means |
US20010055812A1 (en) | 1995-12-05 | 2001-12-27 | Alec Mian | Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
AU702403B2 (en) | 1995-12-05 | 1999-02-18 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
US5721123A (en) | 1996-01-05 | 1998-02-24 | Microfab Technology, Inc. | Methods and apparatus for direct heating of biological material |
JPH09189704A (ja) | 1996-01-10 | 1997-07-22 | Hitachi Ltd | 自動化学分析装置 |
US5863502A (en) | 1996-01-24 | 1999-01-26 | Sarnoff Corporation | Parallel reaction cassette and associated devices |
FR2744803B1 (fr) | 1996-02-12 | 1998-03-13 | Bio Merieux | Procede et dispositif de traitement d'une carte d'analyse |
JP4278712B2 (ja) | 1996-06-04 | 2009-06-17 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | Dna増幅を蛍光でモニタリングするためのシステムと方法 |
JPH1019884A (ja) | 1996-06-28 | 1998-01-23 | Toa Medical Electronics Co Ltd | 遠心分離式血液分析計 |
US6143248A (en) | 1996-08-12 | 2000-11-07 | Gamera Bioscience Corp. | Capillary microvalve |
RO119751B1 (ro) | 1997-02-28 | 2005-02-28 | Burstein Laboratories, Inc. | Disc optic, aparat pentru efectuarea unui control optic, metodă pentru detectarea prezenţei sau absenţei unui analit într-o probă şi metodă de control al unei probe bioligice, chimice sau biochimice |
AUPO652997A0 (en) * | 1997-04-30 | 1997-05-29 | Kindconi Pty Limited | Temperature cycling device and method |
WO1998050147A1 (en) | 1997-05-09 | 1998-11-12 | The Regents Of The University Of California | Peltier-assisted microfabricated reaction chambers for thermal cycling |
AU7591998A (en) | 1997-05-23 | 1998-12-11 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
US5822903A (en) | 1997-08-08 | 1998-10-20 | Craig T. Luttes | Externally adjustable slide trigger assemblies for handguns |
EP1004015B1 (de) | 1997-08-15 | 2004-01-02 | Alexion Pharmaceuticals, Inc. | Vorrichtung zur durchführung von nachweisen an reaktionsstellen |
AU8915998A (en) * | 1997-08-19 | 1999-03-08 | Siemens Corporation | Vehicle information system |
US6558947B1 (en) | 1997-09-26 | 2003-05-06 | Applied Chemical & Engineering Systems, Inc. | Thermal cycler |
US6013513A (en) | 1997-10-30 | 2000-01-11 | Motorola, Inc. | Molecular detection apparatus |
US6121054A (en) | 1997-11-19 | 2000-09-19 | Trega Biosciences, Inc. | Method for separation of liquid and solid phases for solid phase organic syntheses |
US6007914A (en) | 1997-12-01 | 1999-12-28 | 3M Innovative Properties Company | Fibers of polydiorganosiloxane polyurea copolymers |
US5948227A (en) * | 1997-12-17 | 1999-09-07 | Caliper Technologies Corp. | Methods and systems for performing electrophoretic molecular separations |
GB9808836D0 (en) | 1998-04-27 | 1998-06-24 | Amersham Pharm Biotech Uk Ltd | Microfabricated apparatus for cell based assays |
GB9809943D0 (en) | 1998-05-08 | 1998-07-08 | Amersham Pharm Biotech Ab | Microfluidic device |
US6093370A (en) | 1998-06-11 | 2000-07-25 | Hitachi, Ltd. | Polynucleotide separation method and apparatus therefor |
US6153148A (en) * | 1998-06-15 | 2000-11-28 | Becton, Dickinson And Company | Centrifugal hematology disposable |
EP1088229A4 (de) | 1998-06-25 | 2002-05-08 | Caliper Techn Corp | Hochdurchsatz verfahren, systeme und vorrichtung um zell-basierende screeningassays durchzuführen |
WO2000005582A2 (en) | 1998-07-21 | 2000-02-03 | Burstein Laboratories, Inc. | Optical disc-based assay devices and methods |
US6572830B1 (en) | 1998-10-09 | 2003-06-03 | Motorola, Inc. | Integrated multilayered microfludic devices and methods for making the same |
GB9828785D0 (en) | 1998-12-30 | 1999-02-17 | Amersham Pharm Biotech Ab | Sequencing systems |
ATE508200T1 (de) | 1999-02-23 | 2011-05-15 | Caliper Life Sciences Inc | Sequenzierung durch inkorporation |
AU3886599A (en) | 1999-05-05 | 2000-11-21 | 3M Innovative Properties Company | Silicone adhesives, articles, and methods |
WO2000069560A1 (en) | 1999-05-14 | 2000-11-23 | Gamera Bioscience Corporation | A centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids |
JP2004529312A (ja) | 1999-06-18 | 2004-09-24 | ガメラ バイオサイエンス コーポレイション | 小型化均一アッセイ用のデバイスおよび方法 |
AU5887000A (en) | 1999-06-22 | 2001-01-09 | Tecan Trading Ag | Devices and methods for the performance of miniaturized in vitro amplification assays |
DE60034347T2 (de) | 1999-07-16 | 2007-12-13 | Applera Corp., Foster City | Vorrichtung und verfahren für hochdichte elektrophorese |
WO2001007892A1 (en) * | 1999-07-27 | 2001-02-01 | Esperion Therapeutics, Inc. | Method and device for measurement of cholesterol efflux |
JP2003533682A (ja) | 2000-05-15 | 2003-11-11 | テカン・トレーディング・アクチェンゲゼルシャフト | 双方向流動遠心ミクロ流体装置 |
US6720187B2 (en) | 2000-06-28 | 2004-04-13 | 3M Innovative Properties Company | Multi-format sample processing devices |
US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
US6648853B1 (en) | 2000-10-31 | 2003-11-18 | Agilent Technologies Inc. | Septum |
US6467275B1 (en) | 2000-12-07 | 2002-10-22 | International Business Machines Corporation | Cold point design for efficient thermoelectric coolers |
US6617136B2 (en) | 2001-04-24 | 2003-09-09 | 3M Innovative Properties Company | Biological sample processing methods and compositions that include surfactants |
WO2004058405A1 (en) | 2001-05-02 | 2004-07-15 | 3M Innovative Properties Company | Sample processing device with resealable process chamber |
US6565808B2 (en) | 2001-05-18 | 2003-05-20 | Acon Laboratories | Line test device and methods of use |
US6833536B2 (en) | 2002-05-22 | 2004-12-21 | Applera Corporation | Non-contact radiant heating and temperature sensing device for a chemical reaction chamber |
US7198759B2 (en) | 2002-07-26 | 2007-04-03 | Applera Corporation | Microfluidic devices, methods, and systems |
EP1534982A4 (de) | 2002-07-26 | 2006-02-08 | Applera Corp | Einwege-mikrokugelventil für mikrofluidvorrichtung |
WO2004011365A2 (en) | 2002-07-26 | 2004-02-05 | Applera Corporation | Micro-channel design features that facilitate centripetal fluid transfer |
US7041258B2 (en) | 2002-07-26 | 2006-05-09 | Applera Corporation | Micro-channel design features that facilitate centripetal fluid transfer |
US6817373B2 (en) | 2002-07-26 | 2004-11-16 | Applera Corporation | One-directional microball valve for a microfluidic device |
WO2004011681A1 (en) | 2002-07-26 | 2004-02-05 | Applera Corporation | Microfluidic device including purification column with excess diluent, and method |
-
2001
- 2001-04-18 US US09/837,073 patent/US6720187B2/en not_active Expired - Fee Related
-
2002
- 2002-03-12 AT AT02723423T patent/ATE337544T1/de not_active IP Right Cessation
- 2002-03-12 EP EP06017431A patent/EP1729105A1/de not_active Withdrawn
- 2002-03-12 EP EP02723423A patent/EP1379852B1/de not_active Expired - Lifetime
- 2002-03-12 DE DE60214150T patent/DE60214150T2/de not_active Expired - Lifetime
- 2002-03-12 CA CA002443511A patent/CA2443511A1/en not_active Abandoned
- 2002-03-12 JP JP2002583938A patent/JP4205434B2/ja not_active Expired - Fee Related
- 2002-03-12 WO PCT/US2002/007663 patent/WO2002086454A1/en active IP Right Grant
-
2004
- 2004-03-24 US US10/808,124 patent/US7939018B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4205434B2 (ja) | 2009-01-07 |
JP2004536291A (ja) | 2004-12-02 |
EP1379852A4 (de) | 2004-11-17 |
US7939018B2 (en) | 2011-05-10 |
ATE337544T1 (de) | 2006-09-15 |
DE60214150T2 (de) | 2007-08-23 |
EP1379852B1 (de) | 2006-08-23 |
CA2443511A1 (en) | 2002-10-31 |
US20020001848A1 (en) | 2002-01-03 |
US6720187B2 (en) | 2004-04-13 |
EP1729105A1 (de) | 2006-12-06 |
EP1379852A1 (de) | 2004-01-14 |
WO2002086454A1 (en) | 2002-10-31 |
US20040179974A1 (en) | 2004-09-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60214150D1 (de) | Multiformat-probenprozessierungsvorrichtungen, -verfahren und -systeme | |
DE60216433D1 (de) | Lothöckermetallurgieschienen für versorgungs- und massenleitungsführung | |
GB2418529B (en) | X-ray tube electron sources | |
JP2004536291A5 (de) | ||
TW200620633A (en) | Stacked semiconductor memory device | |
DE60217206D1 (de) | Gasgekühlte elektrostatische Halteplatte mit stiftförmigen Distanzhaltern für Vakuumanwendungen | |
WO2003014645A3 (en) | Improved lamphead for a rapid thermal processing chamber | |
DE69737955D1 (de) | Gerät zur reduzierung der spannung der herzwand | |
DE602005020291D1 (de) | Verbinder, verbinder-zusammenbausystem und verfahr | |
WO2006094081A3 (en) | Electromagnetic device with integral non-linear component | |
ATE405732T1 (de) | Abgasbehandlungsvorrichtung und herstellungsverfahren dafür | |
AU2003245906A8 (en) | Loosely-biased heterogeneous reconfigurable arrays | |
DE60215019D1 (de) | Trennung von integrierten optischen modulen und strukturen | |
ATE425811T1 (de) | Chemische und biologische detektionsarrays | |
DE60239283D1 (de) | Optischer Kreuzvermittlungsschalter | |
ATE224762T1 (de) | Plasmaunterstützte gasbehandlung | |
DK1434632T3 (da) | Legetöjsfartöj omfattende fleksible elementer | |
DE60333882D1 (de) | Druckabhängiger Mehrrichtungseingabeeinrichtung | |
ITMI20021352A1 (it) | Dispositivo di connessione tra organi di una macchina | |
ATE460667T1 (de) | Mikroarray-vorrichtungen mit steuerbarem reaktionsvolumen | |
TW200627569A (en) | Semiconductor integrated circuit and its manufacturing method | |
PT1301437E (pt) | Dispositivo para tratamento de agua | |
DE60204778D1 (de) | Zweidimensionale pyramidenfilterarchitektur | |
WO2004010221A3 (en) | Apparatus and method providing substantially two-dimensionally uniform irradiation | |
WO2007053477A3 (en) | Electromagnetic device with frequency downconverter |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |