DE60212153D1 - Tetrahydropyranderivate und ihre verwendung als therapeutika - Google Patents
Tetrahydropyranderivate und ihre verwendung als therapeutikaInfo
- Publication number
- DE60212153D1 DE60212153D1 DE60212153T DE60212153T DE60212153D1 DE 60212153 D1 DE60212153 D1 DE 60212153D1 DE 60212153 T DE60212153 T DE 60212153T DE 60212153 T DE60212153 T DE 60212153T DE 60212153 D1 DE60212153 D1 DE 60212153D1
- Authority
- DE
- Germany
- Prior art keywords
- sup
- sub
- replaced
- hydrogen atoms
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 206010036376 Postherpetic Neuralgia Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0121874 | 2001-09-10 | ||
| GBGB0121874.2A GB0121874D0 (en) | 2001-09-10 | 2001-09-10 | Therapeutic agents |
| PCT/GB2002/004085 WO2003022839A1 (en) | 2001-09-10 | 2002-09-06 | Tetrahydropyran derivatives and their use as therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60212153D1 true DE60212153D1 (de) | 2006-07-20 |
| DE60212153T2 DE60212153T2 (de) | 2007-05-24 |
Family
ID=9921835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60212153T Expired - Lifetime DE60212153T2 (de) | 2001-09-10 | 2002-09-06 | Tetrahydropyranderivate und ihre verwendung als therapeutika |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7265110B2 (de) |
| EP (1) | EP1427723B1 (de) |
| JP (1) | JP2005506329A (de) |
| KR (1) | KR20040045435A (de) |
| CN (1) | CN1578778A (de) |
| AT (1) | ATE328881T1 (de) |
| BR (1) | BR0212454A (de) |
| CA (1) | CA2459464A1 (de) |
| DE (1) | DE60212153T2 (de) |
| ES (1) | ES2263803T3 (de) |
| GB (1) | GB0121874D0 (de) |
| IL (1) | IL160785A0 (de) |
| MX (1) | MXPA04002295A (de) |
| NO (1) | NO20041431L (de) |
| PL (1) | PL368208A1 (de) |
| RU (1) | RU2004110950A (de) |
| WO (1) | WO2003022839A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0121874D0 (en) | 2001-09-10 | 2001-10-31 | Merck Sharp & Dohme | Therapeutic agents |
| GB0217068D0 (en) * | 2002-07-23 | 2002-08-28 | Merck Sharp & Dohme | Therapeutic agents |
| JP2006519822A (ja) * | 2003-03-07 | 2006-08-31 | メルク シャープ エンド ドーム リミテッド | タキキニン拮抗薬としてのテトラヒドロピラン化合物 |
| US11773127B2 (en) * | 2017-11-08 | 2023-10-03 | Washington University | Compounds and methods for treating bacterial infections |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0906315A1 (de) * | 1996-06-21 | 1999-04-07 | MERCK SHARP & DOHME LTD. | Spiro-piperdin-derivate und ihre verwendung als therapeutica |
| CO5150225A1 (es) | 1999-03-19 | 2002-04-29 | Merck Sharp & Dohme | Derivados del tetrahidropirano y su uso como agentes terapeuticos |
| GB0020721D0 (en) * | 2000-08-22 | 2000-10-11 | Merck Sharp & Dohme | Therapeutic agents |
| GB0121874D0 (en) | 2001-09-10 | 2001-10-31 | Merck Sharp & Dohme | Therapeutic agents |
-
2001
- 2001-09-10 GB GBGB0121874.2A patent/GB0121874D0/en not_active Ceased
-
2002
- 2002-09-06 ES ES02755343T patent/ES2263803T3/es not_active Expired - Lifetime
- 2002-09-06 IL IL16078502A patent/IL160785A0/xx unknown
- 2002-09-06 KR KR10-2004-7003573A patent/KR20040045435A/ko not_active Application Discontinuation
- 2002-09-06 DE DE60212153T patent/DE60212153T2/de not_active Expired - Lifetime
- 2002-09-06 BR BR0212454-8A patent/BR0212454A/pt not_active Application Discontinuation
- 2002-09-06 CA CA002459464A patent/CA2459464A1/en not_active Abandoned
- 2002-09-06 PL PL02368208A patent/PL368208A1/xx not_active Application Discontinuation
- 2002-09-06 US US10/488,842 patent/US7265110B2/en not_active Expired - Fee Related
- 2002-09-06 MX MXPA04002295A patent/MXPA04002295A/es not_active Application Discontinuation
- 2002-09-06 RU RU2004110950/04A patent/RU2004110950A/ru not_active Application Discontinuation
- 2002-09-06 WO PCT/GB2002/004085 patent/WO2003022839A1/en active IP Right Grant
- 2002-09-06 CN CNA028214706A patent/CN1578778A/zh active Pending
- 2002-09-06 JP JP2003526914A patent/JP2005506329A/ja not_active Ceased
- 2002-09-06 EP EP02755343A patent/EP1427723B1/de not_active Expired - Lifetime
- 2002-09-06 AT AT02755343T patent/ATE328881T1/de not_active IP Right Cessation
-
2004
- 2004-04-06 NO NO20041431A patent/NO20041431L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20040254184A1 (en) | 2004-12-16 |
| EP1427723A1 (de) | 2004-06-16 |
| CA2459464A1 (en) | 2003-03-20 |
| WO2003022839A1 (en) | 2003-03-20 |
| EP1427723B1 (de) | 2006-06-07 |
| DE60212153T2 (de) | 2007-05-24 |
| GB0121874D0 (en) | 2001-10-31 |
| ATE328881T1 (de) | 2006-06-15 |
| NO20041431L (no) | 2004-06-01 |
| JP2005506329A (ja) | 2005-03-03 |
| PL368208A1 (en) | 2005-03-21 |
| BR0212454A (pt) | 2004-10-19 |
| IL160785A0 (en) | 2004-08-31 |
| RU2004110950A (ru) | 2005-04-10 |
| MXPA04002295A (es) | 2004-06-18 |
| KR20040045435A (ko) | 2004-06-01 |
| ES2263803T3 (es) | 2006-12-16 |
| CN1578778A (zh) | 2005-02-09 |
| US7265110B2 (en) | 2007-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |