PL368208A1 - Tetrahydropyran derivatives and their use as therapeutic agents - Google Patents

Tetrahydropyran derivatives and their use as therapeutic agents

Info

Publication number
PL368208A1
PL368208A1 PL02368208A PL36820802A PL368208A1 PL 368208 A1 PL368208 A1 PL 368208A1 PL 02368208 A PL02368208 A PL 02368208A PL 36820802 A PL36820802 A PL 36820802A PL 368208 A1 PL368208 A1 PL 368208A1
Authority
PL
Poland
Prior art keywords
sup
sub
therapeutic agents
replaced
hydrogen atoms
Prior art date
Application number
PL02368208A
Other languages
English (en)
Polish (pl)
Inventor
Pineiro Jose Luis Castro
Duncan Edward Shaw
Brian John Williams
Original Assignee
Merck Sharp & Dohme Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme Limited filed Critical Merck Sharp & Dohme Limited
Publication of PL368208A1 publication Critical patent/PL368208A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
PL02368208A 2001-09-10 2002-09-06 Tetrahydropyran derivatives and their use as therapeutic agents PL368208A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121874.2A GB0121874D0 (en) 2001-09-10 2001-09-10 Therapeutic agents
PCT/GB2002/004085 WO2003022839A1 (en) 2001-09-10 2002-09-06 Tetrahydropyran derivatives and their use as therapeutic agents

Publications (1)

Publication Number Publication Date
PL368208A1 true PL368208A1 (en) 2005-03-21

Family

ID=9921835

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02368208A PL368208A1 (en) 2001-09-10 2002-09-06 Tetrahydropyran derivatives and their use as therapeutic agents

Country Status (17)

Country Link
US (1) US7265110B2 (xx)
EP (1) EP1427723B1 (xx)
JP (1) JP2005506329A (xx)
KR (1) KR20040045435A (xx)
CN (1) CN1578778A (xx)
AT (1) ATE328881T1 (xx)
BR (1) BR0212454A (xx)
CA (1) CA2459464A1 (xx)
DE (1) DE60212153T2 (xx)
ES (1) ES2263803T3 (xx)
GB (1) GB0121874D0 (xx)
IL (1) IL160785A0 (xx)
MX (1) MXPA04002295A (xx)
NO (1) NO20041431L (xx)
PL (1) PL368208A1 (xx)
RU (1) RU2004110950A (xx)
WO (1) WO2003022839A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0121874D0 (en) 2001-09-10 2001-10-31 Merck Sharp & Dohme Therapeutic agents
GB0217068D0 (en) * 2002-07-23 2002-08-28 Merck Sharp & Dohme Therapeutic agents
US7393858B2 (en) * 2003-03-07 2008-07-01 Merck Sharp & Dohme Ltd. Tetrahydropyran compounds as tachykinin antagonists
US11773127B2 (en) * 2017-11-08 2023-10-03 Washington University Compounds and methods for treating bacterial infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2257964A1 (en) * 1996-06-21 1997-12-31 Merck Sharp & Dohme Limited Spiro-piperidine derivatives and their use as therapeutic agents
CO5150225A1 (es) * 1999-03-19 2002-04-29 Merck Sharp & Dohme Derivados del tetrahidropirano y su uso como agentes terapeuticos
GB0020721D0 (en) * 2000-08-22 2000-10-11 Merck Sharp & Dohme Therapeutic agents
GB0121874D0 (en) 2001-09-10 2001-10-31 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
US7265110B2 (en) 2007-09-04
IL160785A0 (en) 2004-08-31
NO20041431L (no) 2004-06-01
KR20040045435A (ko) 2004-06-01
CN1578778A (zh) 2005-02-09
EP1427723B1 (en) 2006-06-07
ES2263803T3 (es) 2006-12-16
DE60212153D1 (de) 2006-07-20
JP2005506329A (ja) 2005-03-03
EP1427723A1 (en) 2004-06-16
WO2003022839A1 (en) 2003-03-20
GB0121874D0 (en) 2001-10-31
BR0212454A (pt) 2004-10-19
CA2459464A1 (en) 2003-03-20
RU2004110950A (ru) 2005-04-10
MXPA04002295A (es) 2004-06-18
US20040254184A1 (en) 2004-12-16
ATE328881T1 (de) 2006-06-15
DE60212153T2 (de) 2007-05-24

Similar Documents

Publication Publication Date Title
IL176107A0 (en) Azabicyclic heterocycles as cannabinoid receptor modulators
HK1095138A1 (en) Azabicyclic heterocycles as cannabinoid receptor modulators
NO20083114L (no) Polysykliske indazolderivater som er ERK-inhibitorer
HK1068136A1 (en) Muscarinic antagonists
TW200726765A (en) Triazolopyridine cannabinoid receptor 1 antagonists
NO20052182L (no) Nye forbindelser
SE0202463D0 (sv) Novel compounds
NO20055655L (no) Anvendelse av azetidinkarboksamidderivater i terapi
SG159380A1 (en) Heteroaryl compounds useful as inhibitors of gsk-3
DE60315674D1 (de) Neue imidazopyridine und ihre verwendung
HK1062677A1 (en) 17Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
MXPA00006605A (es) Compuestos de carbonil-indol biciclicos como agentes antiinflamatorios/analgesicos.
NO20062255L (no) 4-anilino-3-kinolinkarbonitriler for behandling av kronisk myelogenos leukemi (CML)
AU3304400A (en) Tetrahydropyran derivatives and their use as therapeutic agents
GB0314967D0 (en) Piperazine derivatives
WO2005046672A3 (fr) Utilisation d’inhibiteurs de glucosidase pour une therapie de la mucoviscidose
UA97483C2 (ru) Производное пиримидина в качестве ингибитора pi3k и его применение
JO2231B1 (en) Derivatives of Trahydroperan and its use as a therapeutic agent
TW200420292A (en) Benzofuran derivative
IL160785A0 (en) Tetrahydropyran derivatives and their use as therapeutic agents
SE0302572D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MY139228A (en) Imidazolinylmethyl aralkylsulfonamides
ATE411311T1 (de) Tetrahydropyranverbindungen als tachykininantagonisten
MXPA05014127A (es) Uso de derivados de biciclo[2.2.1]heptano para la preparacion de composiciones farmaceuticas neuroprotectoras.
MX2022015986A (es) Derivados de aminopirimidinilo.

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)