DE60203265D1 - Stents mit arzneimittelhaltigem amphiphilem polymerüberzug - Google Patents

Stents mit arzneimittelhaltigem amphiphilem polymerüberzug

Info

Publication number
DE60203265D1
DE60203265D1 DE60203265T DE60203265T DE60203265D1 DE 60203265 D1 DE60203265 D1 DE 60203265D1 DE 60203265 T DE60203265 T DE 60203265T DE 60203265 T DE60203265 T DE 60203265T DE 60203265 D1 DE60203265 D1 DE 60203265D1
Authority
DE
Germany
Prior art keywords
amphiphilem
stents
medication
polymer cover
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60203265T
Other languages
English (en)
Other versions
DE60203265T2 (de
Inventor
Lennard Lewis
William Leppard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE60203265D1 publication Critical patent/DE60203265D1/de
Publication of DE60203265T2 publication Critical patent/DE60203265T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60203265T 2001-01-11 2002-01-11 Stents mit arzneimittelhaltigem amphiphilem polymerüberzug Expired - Lifetime DE60203265T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0100760.8A GB0100760D0 (en) 2001-01-11 2001-01-11 Drug delivery from stents
GB0100760 2001-01-11
PCT/GB2002/000104 WO2002055122A1 (en) 2001-01-11 2002-01-11 Stens with drug-containing amphiphilic polymer coating

Publications (2)

Publication Number Publication Date
DE60203265D1 true DE60203265D1 (de) 2005-04-21
DE60203265T2 DE60203265T2 (de) 2006-03-30

Family

ID=9906673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60203265T Expired - Lifetime DE60203265T2 (de) 2001-01-11 2002-01-11 Stents mit arzneimittelhaltigem amphiphilem polymerüberzug

Country Status (8)

Country Link
US (3) US7833544B2 (de)
EP (1) EP1357956B1 (de)
JP (1) JP5192116B2 (de)
AT (1) ATE290895T1 (de)
DE (1) DE60203265T2 (de)
ES (1) ES2239228T3 (de)
GB (1) GB0100760D0 (de)
WO (1) WO2002055122A1 (de)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399480B2 (en) * 1997-09-26 2008-07-15 Abbott Laboratories Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
US20030129215A1 (en) * 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US20060198867A1 (en) * 1997-09-25 2006-09-07 Abbott Laboratories, Inc. Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
US6890546B2 (en) 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US8257726B2 (en) * 1997-09-26 2012-09-04 Abbott Laboratories Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
US8057816B2 (en) * 1997-09-26 2011-11-15 Abbott Laboratories Compositions and methods of administering paclitaxel with other drugs using medical devices
US8394398B2 (en) 1997-09-26 2013-03-12 Abbott Laboratories Methods of administering rapamycin analogs with anti-inflammatories using medical devices
US7378105B2 (en) 1997-09-26 2008-05-27 Abbott Laboratories Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
US7357942B2 (en) 1997-09-26 2008-04-15 Abbott Laboratories Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
US8257725B2 (en) * 1997-09-26 2012-09-04 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
US20060240070A1 (en) * 1998-09-24 2006-10-26 Cromack Keith R Delivery of highly lipophilic agents via medical devices
US8257724B2 (en) * 1998-09-24 2012-09-04 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
US7455853B2 (en) * 1998-09-24 2008-11-25 Abbott Cardiovascular Systems Inc. Medical devices containing rapamycin analogs
US7960405B2 (en) 1998-09-24 2011-06-14 Abbott Laboratories Compounds and methods for treatment and prevention of diseases
DE10107795B4 (de) * 2001-02-13 2014-05-15 Berlex Ag Gefäßstütze mit einem Grundkörper, Verfahren zur Herstellung der Gefäßstütze, Vorrichtung zur Beschichtung der Gefäßstütze
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
EP1418925A4 (de) * 2001-07-31 2009-09-02 Tyco Healthcare Biologisch resorbierbare klebeverbindungen und -zusammensetzungen
US20080145402A1 (en) * 2001-09-10 2008-06-19 Abbott Cardiovascular Systems Inc. Medical Devices Containing Rapamycin Analogs
KR101004224B1 (ko) 2002-02-01 2010-12-27 어리어드 파마슈티칼스, 인코포레이티드 인 함유 화합물 및 이의 용도
EP1499367A1 (de) * 2002-04-24 2005-01-26 Poly-Med, Inc. Vielseitige beschichtung für endovaskuläre gefässstützen zur restenoseprophylaxe
DE10228078B3 (de) * 2002-06-18 2004-02-26 Innovent E.V. Technologieentwicklung Mittel zur Beschichtung von Implantaten sowie Verfahren zur Beschichtung von Implantaten
AU2003218077B2 (en) * 2002-09-06 2009-10-08 Abbott Laboratories Medical device having hydration inhibitor
EP1556430B1 (de) * 2002-10-28 2009-06-24 Tyco Healthcare Group Lp Biologisch absorbierbare adhäsive verbindungen
US7144419B2 (en) 2003-01-24 2006-12-05 Medtronic Vascular, Inc. Drug-polymer coated stent with blended phenoxy and styrenic block copolymers
EP1610823B1 (de) 2003-03-28 2011-09-28 Innovational Holdings, LLC Implantierbares medizinprodukt mit kontinuierlichem mittel-konzentrationsgefälle
DE602004018509D1 (de) * 2003-08-19 2009-01-29 Polybiomed Ltd Polymerisches arzneimittelfreisetzungssystem für medizinische geräte
US7488343B2 (en) * 2003-09-16 2009-02-10 Boston Scientific Scimed, Inc. Medical devices
US8309112B2 (en) 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
US8562505B2 (en) 2004-02-20 2013-10-22 The Children's Hospital Of Philadelphia Uniform field magnetization and targeting of therapeutic formulations
US9028829B2 (en) * 2004-02-20 2015-05-12 The Children's Hospital Of Philadelphia Uniform field magnetization and targeting of therapeutic formulations
US7846201B2 (en) * 2004-02-20 2010-12-07 The Children's Hospital Of Philadelphia Magnetically-driven biodegradable gene delivery nanoparticles formulated with surface-attached polycationic complex
US8137397B2 (en) * 2004-02-26 2012-03-20 Boston Scientific Scimed, Inc. Medical devices
ATE534424T1 (de) * 2004-03-19 2011-12-15 Abbott Lab Mehrfache arzneiabgabe aus einem ballon und eine prothese
US20100030183A1 (en) * 2004-03-19 2010-02-04 Toner John L Method of treating vascular disease at a bifurcated vessel using a coated balloon
US8431145B2 (en) * 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US20070027523A1 (en) * 2004-03-19 2007-02-01 Toner John L Method of treating vascular disease at a bifurcated vessel using coated balloon
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
CA2577108A1 (en) 2004-08-31 2006-03-09 C.R. Bard, Inc. Self-sealing ptfe graft with kink resistance
DE102004046244A1 (de) * 2004-09-22 2006-03-30 Orlowski, Michael, Dr. Beschichtetes Coronarstentsystem
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US20060134168A1 (en) 2004-12-07 2006-06-22 Chappa Ralph A Coatings with crystallized active agent(s) and methods
CA2595633C (en) 2005-02-09 2013-11-19 Ahmad R. Hadba Synthetic sealants
WO2006102359A2 (en) * 2005-03-23 2006-09-28 Abbott Laboratories Delivery of highly lipophilic agents via medical devices
JP5242374B2 (ja) 2005-03-23 2013-07-24 アボット・ラボラトリーズ 組成物ならびに長期効力を得るための医療機器を用いたラパマイシン類縁体の投与方法
DE102005015128B4 (de) * 2005-03-31 2008-12-11 Bayer Schering Pharma Aktiengesellschaft Wafer enthaltend Steroidhormone
US20060240253A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Guidewire and tube with lubricious coating
US20060240060A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060241000A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious compound and medical device made of the same
US20060240059A1 (en) * 2005-04-22 2006-10-26 Cardiac Pacemakers, Inc. Lubricious eluting polymer blend and coating made from the same
US8044234B2 (en) * 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20090177226A1 (en) * 2005-05-05 2009-07-09 Jon Reinprecht Bioabsorbable Surgical Compositions
US20100100124A1 (en) * 2005-05-05 2010-04-22 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20100016888A1 (en) * 2005-05-05 2010-01-21 Allison Calabrese Surgical Gasket
JP2008543376A (ja) * 2005-06-08 2008-12-04 シー・アール・バード・インコーポレーテッド 無機生体適合性カルシウム塩を有するグラフト及びステント
EP1890641B1 (de) 2005-06-17 2017-04-19 C.R. Bard, Inc. Gefässstütze mit knickfestigkeit nach dem klemmen
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
JP5756588B2 (ja) 2005-07-15 2015-07-29 ミセル テクノロジーズ、インコーポレイテッド 制御されたモルホロジーの薬剤粉末を含むポリマーコーティング
US20090062909A1 (en) * 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
AU2011256902B2 (en) * 2005-07-15 2015-03-12 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
KR101492545B1 (ko) 2005-07-15 2015-02-12 미셀 테크놀로지즈, 인코포레이티드 제어된 형태의 약물 분말을 함유하는 중합체 코팅
US20100268321A1 (en) * 2005-09-06 2010-10-21 C R Bard, Inc. Drug-releasing graft
DE102005051587A1 (de) * 2005-10-27 2007-05-03 Consortium für elektrochemische Industrie GmbH Zwitterionische Strukturelemente aufweisende Partikel
WO2007056761A2 (en) 2005-11-09 2007-05-18 C.R. Bard Inc. Grafts and stent grafts having a radiopaque marker
US7553546B1 (en) 2005-11-16 2009-06-30 Pacesetter, Inc. Polyethylene oxide and silicone copolymers and their usage on medical devices
US7708774B1 (en) 2005-11-16 2010-05-04 Pacesetter, Inc. Polyethylene oxide and silicone copolymers and their usage on medical devices
US7715922B1 (en) 2005-11-16 2010-05-11 Pacesetter, Inc. Polyethylene oxide and polyisobutylene copolymers and their usage on medical devices
US20070116736A1 (en) * 2005-11-23 2007-05-24 Argentieri Dennis C Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury
CA2628579C (en) * 2005-12-06 2014-07-08 Tyco Healthcare Group Lp Carbodiimide crosslinking of functionalized polethylene glycols
EP1968483A4 (de) 2005-12-06 2010-07-21 Tyco Healthcare Bioabsorbierbare chirurgische zusammensetzung
US8288477B2 (en) * 2005-12-06 2012-10-16 Tyco Healthcare Group Lp Bioabsorbable compounds and compositions containing them
JP5333911B2 (ja) * 2005-12-06 2013-11-06 コヴィディエン リミテッド パートナーシップ 生体適合性外科用組成物
JP5088894B2 (ja) * 2005-12-06 2012-12-05 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性組織封止剤および接着剤
WO2007067866A2 (en) * 2005-12-07 2007-06-14 Rochal Industries, Llp Conformable bandage and coating material
US8449714B2 (en) * 2005-12-08 2013-05-28 Covidien Lp Biocompatible surgical compositions
EP1966311A4 (de) * 2005-12-08 2012-08-15 Tyco Healthcare Versprühbare zusammensetzungen mit verringerter viskosität
WO2007067764A2 (en) * 2005-12-08 2007-06-14 Tyco Healthcare Group Lp Biocompatible surgical compositions
US8840660B2 (en) * 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
CA2573472A1 (en) * 2006-01-23 2007-07-23 Tyco Healthcare Group Lp Biodegradable hemostatic compositions
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
EP1991161B1 (de) 2006-02-22 2012-11-07 Tyco Healthcare Group, LP Biologisch abbaubare phosphoesterpolyamine
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
PL2019657T3 (pl) 2006-04-26 2015-10-30 Micell Technologies Inc Powłoki zawierające wiele leków
US20080004694A1 (en) * 2006-05-23 2008-01-03 Abbott Laboratories Compositions and methods for administering dexamethasone which promote human coronary artery endothelial cell migration
WO2007146680A1 (en) * 2006-06-06 2007-12-21 Florida State University Research Foundation , Inc. Stabilized silica colloid
JP2009545407A (ja) * 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US20080057104A1 (en) * 2006-09-01 2008-03-06 Joseph Walker Matrix metalloproteinase inhibitor delivering devices
DE602007011114D1 (de) * 2006-09-15 2011-01-20 Boston Scient Scimed Inc Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten
US8052744B2 (en) * 2006-09-15 2011-11-08 Boston Scientific Scimed, Inc. Medical devices and methods of making the same
CA2663250A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
EP2068782B1 (de) 2006-09-15 2011-07-27 Boston Scientific Limited Biologisch erodierbare endoprothesen
EP2076296A2 (de) * 2006-09-15 2009-07-08 Boston Scientific Scimed, Inc. Endoprothese mit einstellbaren oberflächenfunktionen
JP2010503482A (ja) 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 内部人工器官
US8636767B2 (en) * 2006-10-02 2014-01-28 Micell Technologies, Inc. Surgical sutures having increased strength
US9198749B2 (en) 2006-10-12 2015-12-01 C. R. Bard, Inc. Vascular grafts with multiple channels and methods for making
US20080097577A1 (en) * 2006-10-20 2008-04-24 Boston Scientific Scimed, Inc. Medical device hydrogen surface treatment by electrochemical reduction
US9539593B2 (en) * 2006-10-23 2017-01-10 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
EP2066321A2 (de) * 2006-11-20 2009-06-10 Lutonix, Inc. Behandlung von asthma und chronisch obstruktiver lungenerkrankung mit antiproliferativen und entzündungshemmenden mitteln
WO2008083190A2 (en) * 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
EP2111184B1 (de) 2007-01-08 2018-07-25 Micell Technologies, Inc. Stents mit biologisch abbaubaren schichten
NZ580469A (en) * 2007-04-17 2012-05-25 Micell Technologies Inc Coronary stents having biodegradable layers
US7673379B1 (en) 2007-05-11 2010-03-09 Abbott Cardiovascular Systems Inc. Method of producing a stent-balloon assembly
US20110123476A1 (en) * 2007-05-24 2011-05-26 Mbiya Kapiamba Adhesive Formulations
JP2010527746A (ja) * 2007-05-25 2010-08-19 ミセル テクノロジーズ、インコーポレイテッド メディカルデバイスコーティング用ポリマーフィルム
US7858835B2 (en) * 2007-06-27 2010-12-28 Tyco Healthcare Group Lp Foam control for synthetic adhesive/sealant
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
JP2011500916A (ja) * 2007-10-17 2011-01-06 エージェンシー フォー サイエンス, テクノロジー アンド リサーチ 親水性と疎水性のバランスがとれた水溶性蛍光物質
WO2009051780A1 (en) * 2007-10-19 2009-04-23 Micell Technologies, Inc. Drug coated stents
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US9533006B2 (en) * 2007-11-19 2017-01-03 University Of Washington Marine coatings
US20090143855A1 (en) * 2007-11-29 2009-06-04 Boston Scientific Scimed, Inc. Medical Device Including Drug-Loaded Fibers
WO2009079389A2 (en) * 2007-12-14 2009-06-25 Boston Scientific Limited Drug-eluting endoprosthesis
DK2268332T3 (da) * 2008-04-09 2019-05-06 Aachen Scient International Pte Ltd Fremgangsmåde til produktion af en bioaktiv overflade på en endoprostese eller på ballonen af et ballonkateter
MX2010011485A (es) * 2008-04-17 2011-03-01 Micell Technologies Inc Stents que contienen capas bioadsorbibles.
US7998192B2 (en) * 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8202529B2 (en) 2008-05-30 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers
US8986728B2 (en) 2008-05-30 2015-03-24 Abbott Cardiovascular Systems Inc. Soluble implantable device comprising polyelectrolyte with hydrophobic counterions
US8236046B2 (en) * 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
WO2011009096A1 (en) 2009-07-16 2011-01-20 Micell Technologies, Inc. Drug delivery medical device
AU2009270849B2 (en) 2008-07-17 2013-11-21 Micell Technologies, Inc. Drug delivery medical device
US7985252B2 (en) * 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8128951B2 (en) 2008-09-15 2012-03-06 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8114429B2 (en) 2008-09-15 2012-02-14 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8257722B2 (en) 2008-09-15 2012-09-04 Cv Ingenuity Corp. Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US9198968B2 (en) 2008-09-15 2015-12-01 The Spectranetics Corporation Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8382824B2 (en) * 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8834913B2 (en) * 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
EP2403546A2 (de) * 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
CA2756386C (en) * 2009-03-23 2019-01-15 Micell Technologies, Inc. Drug delivery medical device
EP2410954A4 (de) * 2009-03-23 2014-03-05 Micell Technologies Inc Periphere stents mit schichten
JP2012522589A (ja) 2009-04-01 2012-09-27 ミシェル テクノロジーズ,インコーポレイテッド 被覆ステント
MX2011010409A (es) * 2009-04-03 2012-01-20 Ashland Licensing & Intellectu Adhesivo acrilico sensible a la presion curable con radiacion ultravioleta.
WO2010121187A2 (en) * 2009-04-17 2010-10-21 Micell Techologies, Inc. Stents having controlled elution
US20110022158A1 (en) * 2009-07-22 2011-01-27 Boston Scientific Scimed, Inc. Bioerodible Medical Implants
WO2011057224A2 (en) 2009-11-06 2011-05-12 University Of Washington Through Its Center For Commercialization Zwitterionic polymer bioconjugates and related methods
US8951595B2 (en) * 2009-12-11 2015-02-10 Abbott Cardiovascular Systems Inc. Coatings with tunable molecular architecture for drug-coated balloon
US20110144577A1 (en) * 2009-12-11 2011-06-16 John Stankus Hydrophilic coatings with tunable composition for drug coated balloon
US8480620B2 (en) * 2009-12-11 2013-07-09 Abbott Cardiovascular Systems Inc. Coatings with tunable solubility profile for drug-coated balloon
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
WO2011119573A1 (en) * 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
CA2797110C (en) 2010-04-22 2020-07-21 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
US10464100B2 (en) 2011-05-31 2019-11-05 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
US9388127B2 (en) 2012-04-17 2016-07-12 University College Dublin, National University Of Ireland, Dublin Thromboxane receptor antagonists
WO2013156861A2 (en) 2012-04-17 2013-10-24 University College Dublin, National University Of Ireland, Dublin Methods and compounds for treating proliferative disorders and viral infections
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
EP2737894A1 (de) * 2012-12-03 2014-06-04 Debiotech S.A. Intelligente Beschichtung für implantierbare Vorrichtungen
US9808560B2 (en) 2013-03-01 2017-11-07 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, non-thrombogenic elastomeric polyurethanes
CN105307597A (zh) 2013-03-12 2016-02-03 脉胜医疗技术公司 可生物吸收的生物医学植入物
US9545301B2 (en) 2013-03-15 2017-01-17 Covidien Lp Coated medical devices and methods of making and using same
US9872940B2 (en) * 2013-04-01 2018-01-23 Terumo Kabushiki Kaisha Drug coating layer
WO2014186532A1 (en) 2013-05-15 2014-11-20 Micell Technologies, Inc. Bioabsorbable biomedical implants
WO2014192731A1 (ja) * 2013-05-27 2014-12-04 Jsr株式会社 無機材料で構成される表面用の表面処理剤、表面が改質された器具および装置、該器具および装置の製造方法
US9668890B2 (en) 2013-11-22 2017-06-06 Covidien Lp Anti-thrombogenic medical devices and methods
US10525171B2 (en) 2014-01-24 2020-01-07 The Spectranetics Corporation Coatings for medical devices
JP6008213B2 (ja) * 2014-08-06 2016-10-19 リューベン,アレクサンダー 体内プロテーゼ上又はバルーンカテーテルのバルーン上の生体活性表面の製造方法
ES2858551T3 (es) 2015-06-16 2021-09-30 Atxa Therapeutics Ltd Antagonistas del receptor de tromboxano
JP7158993B2 (ja) * 2018-10-15 2022-10-24 千秋 東 ホスホリルコリン基含有共重合体、および生体用医療基材
CN112933301B (zh) * 2019-11-26 2023-01-24 上海微创医疗器械(集团)有限公司 载药植入医疗器械及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2167886C2 (ru) 1991-07-05 2001-05-27 Биокомпэтиблз Лимитед. Полимер, способ получения полимера, поверхность с покрытием, способ покрытия поверхности
GB9301701D0 (en) 1993-01-28 1993-03-17 Biocompatibles Ltd New zwitterionic materials
JPH08507715A (ja) * 1993-03-18 1996-08-20 シーダーズ サイナイ メディカル センター 生体人工部材のための薬剤導入性および放出性重合性コーティング
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
EP0706376B2 (de) 1993-07-19 2007-08-08 Angiotech Pharmaceuticals, Inc. Anti-angiogene mittel und verfahren zu deren verwendung
GB9317178D0 (en) 1993-08-18 1993-10-06 Biocompatibles Ltd Polymer surface coatings
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
JP2001508480A (ja) 1997-01-10 2001-06-26 バイオコンパテイブルズ・リミテツド 重合体
EP1019034A2 (de) 1997-07-01 2000-07-19 Atherogenics, Inc. Verbesserung antioxidativer therapie für hyperproliferative zustanden
EP1011743B1 (de) 1997-08-13 2011-07-27 Boston Scientific Limited Beladung und abgabe von wasserunlöslichen wirkstoffen
WO2000056283A1 (en) 1999-03-24 2000-09-28 The B.F.Goodrich Company Inhibition of matrix metalloproteinases with polymers and pharmaceutical applications thereof
JP5140220B2 (ja) 1999-05-27 2013-02-06 バイオコンパテイブルズ・ユーケイ・リミテツド 局所的な薬剤送達

Also Published As

Publication number Publication date
US8512733B2 (en) 2013-08-20
JP5192116B2 (ja) 2013-05-08
US20110034995A1 (en) 2011-02-10
US20050004661A1 (en) 2005-01-06
US20110034994A1 (en) 2011-02-10
WO2002055122A1 (en) 2002-07-18
JP2004529674A (ja) 2004-09-30
DE60203265T2 (de) 2006-03-30
ATE290895T1 (de) 2005-04-15
EP1357956B1 (de) 2005-03-16
US8512750B2 (en) 2013-08-20
US7833544B2 (en) 2010-11-16
GB0100760D0 (en) 2001-02-21
EP1357956A1 (de) 2003-11-05
ES2239228T3 (es) 2005-09-16

Similar Documents

Publication Publication Date Title
DE60203265D1 (de) Stents mit arzneimittelhaltigem amphiphilem polymerüberzug
WO2004000379A8 (en) Stent coatings with sustained drug release rate
ATE425777T1 (de) Stents mit wirkstofffreisetzungsbeschichtungen
AU2002252372A1 (en) Stent with medicated multi-layer hydrid polymer coating
WO2004030678A3 (en) Polymer compositions containing bioactive agents and methods for their use
ATE509641T1 (de) Beschichtung für implantierbare vorrichtungen und verfahren zu ihrer herstellung
WO2003024455A8 (en) Stent coated with a sustained-release drug delivery and method for use thereof
WO2004030578A3 (en) Multilayer stent
DE60105554D1 (de) Endovaskulärer Stent mit Takrolimus enthaltender Beschichtung
AU2003217329A1 (en) Coated vascular prosthesis and methods of manufacture and use.
DE60330455D1 (de) Arzneimittel abgebender endovaskulärer Stent
BR0213279A (pt) Revestimento de stents para impedir a restenose
WO2006065685A3 (en) Abluminal, multilayer coating constructs for drug-delivery stents
WO2004101018A8 (en) Stent coatings comprising hydrophilic additives
WO2004028571A8 (en) Implantable stent with modified ends
WO2008036548A3 (en) Endoprostheses
DE602005016044D1 (de) Deckbeschichtung enhaltend Heparin für kontrollierte Wirkstoffabgabe
WO2003028780A3 (en) Medical device containing light-protected therapeutic agent
WO2008002632A3 (en) Carbon coating on an implantable device
WO2007056762A3 (en) Grafts and stent grafts having a radiopaque beading
WO1999016416A3 (de) Beschichtete medizinische implantate, verfahren zu ihrer herstellung und ihre verwendung zur restenoseprophylaxe
WO2009085963A3 (en) Drug coated stent having a surface treatment and method of manufacturing
DE69612216T2 (de) Metallblech mit rostpreventiver organischer beschichtung, verfahren zu dessen herstellung und behandlungsflüssigkeit dafür
WO2005055800A3 (en) Therapeutic drug-eluting endoluminal covering
AU4063300A (en) Stent with an integrated film coating for deployment throughout the body

Legal Events

Date Code Title Description
8364 No opposition during term of opposition