DE602005025998D1 - Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs - Google Patents
Verfahren zur diagnose von nicht-kleinzelligem lungenkrebsInfo
- Publication number
- DE602005025998D1 DE602005025998D1 DE602005025998T DE602005025998T DE602005025998D1 DE 602005025998 D1 DE602005025998 D1 DE 602005025998D1 DE 602005025998 T DE602005025998 T DE 602005025998T DE 602005025998 T DE602005025998 T DE 602005025998T DE 602005025998 D1 DE602005025998 D1 DE 602005025998D1
- Authority
- DE
- Germany
- Prior art keywords
- cancer
- diagnosis
- small cellulose
- ghsr1b
- ntsr1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/731—Carrageenans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55578904P | 2004-03-23 | 2004-03-23 | |
PCT/JP2005/005613 WO2005090603A2 (en) | 2004-03-23 | 2005-03-18 | Method for diagnosing non-small cell lung cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005025998D1 true DE602005025998D1 (de) | 2011-03-03 |
Family
ID=34961862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005025998T Active DE602005025998D1 (de) | 2004-03-23 | 2005-03-18 | Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs |
Country Status (9)
Country | Link |
---|---|
US (3) | US7700573B2 (de) |
EP (2) | EP1737979B9 (de) |
JP (2) | JP4938451B2 (de) |
CN (1) | CN1977052B (de) |
AT (1) | ATE496142T1 (de) |
DE (1) | DE602005025998D1 (de) |
ES (1) | ES2360073T3 (de) |
TW (1) | TW200600785A (de) |
WO (1) | WO2005090603A2 (de) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
GB0307403D0 (en) * | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
JP5109131B2 (ja) | 2005-02-10 | 2012-12-26 | オンコセラピー・サイエンス株式会社 | 膀胱癌を診断する方法 |
WO2006090810A2 (en) * | 2005-02-25 | 2006-08-31 | Oncotherapy Science, Inc. | Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides |
US20070082845A1 (en) * | 2005-07-15 | 2007-04-12 | The Penn State Research Foundation | Ferritin as a therapeutic target in abnormal cells |
WO2007013671A2 (en) | 2005-07-27 | 2007-02-01 | Oncotherapy Science, Inc. | Method of diagnosing esophageal cancer |
US9347945B2 (en) * | 2005-12-22 | 2016-05-24 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
US20100137163A1 (en) | 2006-01-11 | 2010-06-03 | Link Darren R | Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors |
WO2007097469A1 (en) * | 2006-02-24 | 2007-08-30 | Oncotherapy Science, Inc. | A dominant negative peptide of imp-3, polynucleotide encoding the same, pharmaceutical composition containing the same, and methods for treating or preventing cancer |
EP2018440A1 (de) * | 2006-04-20 | 2009-01-28 | Oncotherapy Science, Inc. | Nmu-ghsr1b/ntsr1-onkogen-signalweg als therapeutisches ziel bei lungenkrebs |
US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
EP2530168B1 (de) | 2006-05-11 | 2015-09-16 | Raindance Technologies, Inc. | Mikrofluidische Vorrichtungen |
WO2008021123A1 (en) | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
EP2059610A1 (de) * | 2006-08-18 | 2009-05-20 | Oncotherapy Science, Inc. | Imp-1-onkogen als therapieziel und prognoseindikator für lungenkrebs |
JP2010501172A (ja) * | 2006-08-25 | 2010-01-21 | オンコセラピー・サイエンス株式会社 | 肺癌に対する予後マーカーおよび治療標的 |
EP2845912A1 (de) * | 2006-09-12 | 2015-03-11 | Genentech, Inc. | Verfahren und Zusammensetzungen zur Diagnose und Behandlung von Lungenkrebs mithilfe des KIT-Gens als genetischem Marker |
US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
SG183717A1 (en) * | 2007-08-20 | 2012-09-27 | Oncotherapy Science Inc | Foxm1 peptide and medicinal agent comprising the same |
KR20100075858A (ko) * | 2007-08-24 | 2010-07-05 | 온코세라피 사이언스 가부시키가이샤 | 암 관련 유전자,cdca5,epha7,stk31 및 wdhd1 |
CN101855346A (zh) * | 2007-08-24 | 2010-10-06 | 肿瘤疗法科学股份有限公司 | Pkib和naaladl2用作前列腺癌治疗和诊断的靶基因 |
WO2009028580A1 (en) * | 2007-08-24 | 2009-03-05 | Oncotherapy Science, Inc. | Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer therapy and diagnosis |
US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
EP2060583A1 (de) | 2007-10-23 | 2009-05-20 | Ganymed Pharmaceuticals AG | Identifikation Tumor-assoziierter Marker für Diagnose und Therapie |
US9670551B2 (en) | 2007-11-30 | 2017-06-06 | Genomictree, Inc. | Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene |
CN102899415B (zh) | 2007-11-30 | 2014-12-10 | 基因特力株式会社 | 使用膀胱癌特异性甲基化标记基因的膀胱癌诊断试剂盒和芯片 |
US9797017B2 (en) | 2007-11-30 | 2017-10-24 | Genomictree, Inc. | Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene |
US9783857B2 (en) | 2007-11-30 | 2017-10-10 | Genomictree, Inc. | Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene |
US9670552B2 (en) | 2007-11-30 | 2017-06-06 | Genomictree, Inc. | Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene |
US10113203B2 (en) | 2007-11-30 | 2018-10-30 | Genomictree, Inc. | Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene |
ES2584932T3 (es) * | 2008-04-16 | 2016-09-30 | Assistance Publique Hôpitaux De Paris | Métodos para el tratamiento, la evaluación pronóstica y la estadificación de cáncer no microcítico de pulmón |
EP2297581B1 (de) | 2008-07-03 | 2013-04-03 | F. Hoffmann-La Roche AG | Asc als lungenkrebsmarker |
US20110319280A1 (en) * | 2008-07-16 | 2011-12-29 | Oncotherapy Science, Inc. | Ect2 oncogene as a therapeutic target and prognostic indicator for lung and esophageal cancer |
EP2145964A1 (de) * | 2008-07-17 | 2010-01-20 | Universität Zu Köln | Verfahren zur Früherkennung und Prognose von Lungenkrebs |
EP4047367A1 (de) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken |
CA2734979A1 (en) * | 2008-08-27 | 2010-03-04 | Oncotherapy Science, Inc. | Syngr4 for target genes of cancer therapy and diagnosis |
SI2340506T1 (sl) * | 2008-09-09 | 2016-02-29 | Somalogic, Inc. | Biomarkerji za pljučni rak in njihove uporabe |
WO2010037856A2 (en) * | 2008-10-03 | 2010-04-08 | Stichting Katholieke Universiteit, Universitair Medisch Centrum St. Radboud | DYNACTIN-1/p150glued AS A TARGET FOR TUMOR DIAGNOSIS AND THERAPY AND A METHOD FOR IDENTIFYING TARGETABLE DISEASE-RELATED PROTEINS |
ES2538002T3 (es) * | 2009-01-07 | 2015-06-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Métodos para el tratamiento, la evaluación pronóstica y la detección de cáncer de mama |
TWI469791B (zh) * | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Foxm1胜肽以及含此胜肽之疫苗 |
ES2703714T3 (es) | 2009-03-12 | 2019-03-12 | Cancer Prevention & Cure Ltd | Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género |
EP2411148B1 (de) | 2009-03-23 | 2018-02-21 | Raindance Technologies, Inc. | Manipulation von mikrofluidiktröpfchen |
EP2486409A1 (de) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Markiertes nanomaterial auf siliziumbasis mit verbesserten eigenschaften und seine verwendung |
EP2517025B1 (de) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen |
US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
EP3392349A1 (de) | 2010-02-12 | 2018-10-24 | Raindance Technologies, Inc. | Digitale analyse von analyten |
US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
EP3412778A1 (de) | 2011-02-11 | 2018-12-12 | Raindance Technologies, Inc. | Verfahren zur bildung gemischter tröpfchen |
EP3736281A1 (de) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Zusammensetzungen und verfahren für molekulare etikettierung |
EP2714970B1 (de) | 2011-06-02 | 2017-04-19 | Raindance Technologies, Inc. | Enzymquantifizierung |
US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
CN105039520A (zh) * | 2011-08-03 | 2015-11-11 | 西格诺药品有限公司 | 作为lkb1状态的预测性生物标志物的基因表达谱的鉴定 |
GB2496150A (en) * | 2011-11-02 | 2013-05-08 | Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin | Biomarker and target for responsiveness and resistance to cancer targeting agents |
US20130210659A1 (en) | 2012-02-10 | 2013-08-15 | Andrew Watson | Molecular diagnostic screening assay |
WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
ES2836127T3 (es) * | 2013-03-15 | 2021-06-24 | Sera Prognostics Inc | Biomarcadores y métodos para predecir el parto prematuro |
JP2014207883A (ja) * | 2013-03-27 | 2014-11-06 | 国立大学法人岡山大学 | がん幹細胞及びその用途 |
EP2986762B1 (de) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digitale analyse von analyten |
TWI643867B (zh) | 2013-05-24 | 2018-12-11 | 日商腫瘤療法 科學股份有限公司 | 對於th1細胞之imp-3抗原決定位胜肽及含此之疫苗 |
JP6689197B2 (ja) * | 2013-08-19 | 2020-04-28 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | スクリーニング方法 |
US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
EP3090063B1 (de) | 2013-12-31 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Verfahren zur detektion von latentem retrovirus |
EP4353321A2 (de) | 2014-08-04 | 2024-04-17 | OncoTherapy Science, Inc. | Koc1-abgeleitetes peptid und impfstoff damit |
KR20180029046A (ko) | 2015-06-19 | 2018-03-19 | 세라 프로그노스틱스 인코포레이티드 | 조산 예측용 바이오마커 쌍 |
CN105039522A (zh) * | 2015-06-24 | 2015-11-11 | 湖北工业大学 | 基于肽核酸探针的Wnt信号通路中FoxM1基因突变的检测试剂、PCR检测方法及应用 |
US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
BR112018005581A2 (pt) | 2015-10-08 | 2018-10-16 | Oncotherapy Science, Inc. | peptídeo derivado de foxm1 e vacina incluindo o mesmo |
JP2019525774A (ja) * | 2016-07-19 | 2019-09-12 | ブランダイス ユニバーシティー | Rna結合ポリペプチドの標的を同定するための組成物および方法 |
AU2018248293A1 (en) | 2017-04-04 | 2019-10-31 | Lung Cancer Proteomics, Llc | Plasma based protein profiling for early stage lung cancer prognosis |
EP3668996A4 (de) | 2017-08-18 | 2021-04-21 | Sera Prognostics, Inc. | Clock-schwangerschaftsprotein zur vorhersage des entbindungstermins und der zeit bis zur entbindung |
US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
CN111317743B (zh) * | 2020-03-13 | 2022-11-29 | 中国人民解放军第四军医大学 | 一种基于Kif11基因的重组腺相关病毒抑制病理性疼痛的应用 |
TWI781647B (zh) * | 2020-06-09 | 2022-10-21 | 財團法人國家衛生研究院 | 抗人神經降壓素受體抗體及其用途 |
CN114561358B (zh) * | 2022-03-09 | 2023-10-03 | 广州源井生物科技有限公司 | 一种提高细胞慢病毒感染率的增强感染培养基及方法 |
CN115478106B (zh) * | 2022-08-18 | 2023-07-07 | 南方医科大学南方医院 | 一种基于lr对对三阴性乳腺癌进行分型的方法及其应用 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
WO1994025585A1 (en) | 1993-04-26 | 1994-11-10 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
EP0746609A4 (de) | 1991-12-17 | 1997-12-17 | Genpharm Int | Heterologe antikörper produzierende transgene nicht-humane tiere |
ATE381614T1 (de) | 1992-07-24 | 2008-01-15 | Amgen Fremont Inc | Bildung von xenogenen antikörpern |
KR100654645B1 (ko) | 1995-04-27 | 2007-04-04 | 아브게닉스, 인크. | 면역화된 제노마우스 유래의 인간 항체 |
EP0823941A4 (de) | 1995-04-28 | 2001-09-19 | Abgenix Inc | Menschliche antikörper aus xenomäusen |
US5889170A (en) * | 1997-01-31 | 1999-03-30 | Incyte Pharmaceuticals, Inc. | Human integral membrane protein |
US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
US6297364B1 (en) * | 1998-04-17 | 2001-10-02 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof |
US20020103360A1 (en) | 1998-09-01 | 2002-08-01 | Yang Pan | Novel protein related to melanoma-inhibiting protein and uses thereof |
EP1115737A4 (de) * | 1998-09-23 | 2004-11-24 | Cleveland Clinic Foundation | Durch interferon stimulierte und reprimierte gene |
WO2000063353A1 (en) * | 1999-04-20 | 2000-10-26 | Cytokinetics | Human kinesins and methods of producing and purifying human kinesins |
DE19935303A1 (de) * | 1999-07-28 | 2001-02-08 | Aventis Pharma Gmbh | Oligonukleotide zur Inhibierung der Expression von humanem eg5 |
US6617115B1 (en) * | 1999-10-27 | 2003-09-09 | Cytokinetics, Inc. | Methods of screening for modulators of cell proliferation |
WO2001094629A2 (en) | 2000-06-05 | 2001-12-13 | Avalon Pharmaceuticals | Cancer gene determination and therapeutic screening using signature gene sets |
US7358353B2 (en) * | 2000-08-22 | 2008-04-15 | Agensys, Inc. | Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers |
US6706867B1 (en) * | 2000-12-19 | 2004-03-16 | The United States Of America As Represented By The Department Of Health And Human Services | DNA array sequence selection |
JP2005506298A (ja) * | 2001-03-29 | 2005-03-03 | ブリストル−マイヤーズ スクイブ カンパニー | Eg5阻害剤を用いる増殖性疾患の治療方法 |
CA2456334A1 (en) * | 2001-08-16 | 2003-02-27 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Molecular characteristics of non-small cell lung cancer |
US20040009156A1 (en) * | 2001-10-12 | 2004-01-15 | Christoph Reinhard | Antisense therapy using oligonucleotides that target human kinesin genes for treatment of cancer |
US7163927B2 (en) * | 2002-05-23 | 2007-01-16 | Isis Pharmaceuticals, Inc. | Antisense modulation of kinesin-like 1 expression |
EP2213738B1 (de) * | 2002-11-14 | 2012-10-10 | Dharmacon, Inc. | siRNA moleküle gegen Bcl-2 |
CN1926551B (zh) * | 2003-10-27 | 2010-06-16 | 罗斯塔生化科技有限责任公司 | 用于基因沉默的siRNA的设计方法 |
AU2005213464A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Diagnosis and therapeutics for cancer |
-
2005
- 2005-03-18 AT AT05721540T patent/ATE496142T1/de not_active IP Right Cessation
- 2005-03-18 EP EP05721540A patent/EP1737979B9/de not_active Not-in-force
- 2005-03-18 WO PCT/JP2005/005613 patent/WO2005090603A2/en active Application Filing
- 2005-03-18 DE DE602005025998T patent/DE602005025998D1/de active Active
- 2005-03-18 ES ES05721540T patent/ES2360073T3/es active Active
- 2005-03-18 JP JP2006526453A patent/JP4938451B2/ja not_active Expired - Fee Related
- 2005-03-18 EP EP10177195A patent/EP2343384A3/de not_active Withdrawn
- 2005-03-18 CN CN2005800165605A patent/CN1977052B/zh not_active Expired - Fee Related
- 2005-03-18 TW TW094108342A patent/TW200600785A/zh unknown
- 2005-03-18 US US10/593,842 patent/US7700573B2/en not_active Expired - Fee Related
-
2010
- 2010-02-04 US US12/700,669 patent/US7972772B2/en not_active Expired - Fee Related
- 2010-09-24 JP JP2010212951A patent/JP2011039069A/ja not_active Withdrawn
-
2011
- 2011-05-23 US US13/113,732 patent/US20110223687A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1977052A (zh) | 2007-06-06 |
EP1737979A2 (de) | 2007-01-03 |
WO2005090603A2 (en) | 2005-09-29 |
EP2343384A2 (de) | 2011-07-13 |
US20080050378A1 (en) | 2008-02-28 |
US20100173317A1 (en) | 2010-07-08 |
WO2005090603A3 (en) | 2006-03-02 |
EP2343384A3 (de) | 2012-01-04 |
JP4938451B2 (ja) | 2012-05-23 |
ATE496142T1 (de) | 2011-02-15 |
US20110223687A1 (en) | 2011-09-15 |
TW200600785A (en) | 2006-01-01 |
US7700573B2 (en) | 2010-04-20 |
EP1737979B1 (de) | 2011-01-19 |
ES2360073T3 (es) | 2011-05-31 |
CN1977052B (zh) | 2012-09-05 |
US7972772B2 (en) | 2011-07-05 |
JP2007530006A (ja) | 2007-11-01 |
JP2011039069A (ja) | 2011-02-24 |
EP1737979B9 (de) | 2011-09-21 |
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