DE602005025495D1 - Derivate einer arylsulfonamidosubstituierten hydroxamsäure als matrixmetalloproteinaseinhibitoren - Google Patents
Derivate einer arylsulfonamidosubstituierten hydroxamsäure als matrixmetalloproteinaseinhibitorenInfo
- Publication number
- DE602005025495D1 DE602005025495D1 DE602005025495T DE602005025495T DE602005025495D1 DE 602005025495 D1 DE602005025495 D1 DE 602005025495D1 DE 602005025495 T DE602005025495 T DE 602005025495T DE 602005025495 T DE602005025495 T DE 602005025495T DE 602005025495 D1 DE602005025495 D1 DE 602005025495D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- hydroxamic acid
- arylsulfonamidosubstituted
- matrix metalloproteinase
- metalloproteinase inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Lubricants (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000174A ITFI20040174A1 (it) | 2004-08-03 | 2004-08-03 | Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi |
PCT/EP2005/053722 WO2006013193A2 (en) | 2004-08-03 | 2005-07-29 | Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005025495D1 true DE602005025495D1 (de) | 2011-02-03 |
Family
ID=35787488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005025495T Active DE602005025495D1 (de) | 2004-08-03 | 2005-07-29 | Derivate einer arylsulfonamidosubstituierten hydroxamsäure als matrixmetalloproteinaseinhibitoren |
Country Status (14)
Country | Link |
---|---|
US (2) | US7772430B2 (de) |
EP (2) | EP2308837A3 (de) |
JP (1) | JP2008509108A (de) |
CN (1) | CN101076514A (de) |
AT (1) | ATE492530T1 (de) |
AU (1) | AU2005268765B2 (de) |
BR (1) | BRPI0514030A (de) |
CA (1) | CA2580235A1 (de) |
DE (1) | DE602005025495D1 (de) |
IT (1) | ITFI20040174A1 (de) |
MX (1) | MX2007001269A (de) |
RU (2) | RU2406721C2 (de) |
WO (1) | WO2006013193A2 (de) |
ZA (1) | ZA200701798B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102143942A (zh) | 2008-07-14 | 2011-08-03 | 诺瓦提斯公司 | 选择性的基于异羟肟酸的mmp-12 和mmp-13 抑制剂 |
DE102011088926A1 (de) * | 2011-12-19 | 2013-06-20 | Beiersdorf Ag | Haarstylingformulierung zur Erstellung eines flexiblen Haltes durch Einsatz von Octanohydroxamsäure |
BR112014015940B1 (pt) * | 2011-12-28 | 2022-08-09 | Galectin Therapeutics, Inc | Polissacarídeo de grau farmacêutico, composição, e seus usos |
EP2907512A1 (de) | 2014-02-14 | 2015-08-19 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Hemmer von MMP-12 als antivirale Wirkstoffe |
CN105728047B (zh) * | 2016-03-24 | 2017-12-26 | 万华化学集团股份有限公司 | 一种氢甲酰化催化剂及其制备方法和应用 |
JP2017210442A (ja) * | 2016-05-26 | 2017-11-30 | イノレックス インベストメント コーポレイション | マトリックスメタロプロテイナーゼを阻害して皮膚の老化を軽減する方法及び関連の相乗的組成物 |
IT201600083975A1 (it) * | 2016-08-09 | 2018-02-09 | Consorzio Interuniversitario Naz Per La Scienza E Tecnologia Dei Materiali | Acido ialuronico funzionalizzato |
JP6541118B1 (ja) * | 2018-04-27 | 2019-07-10 | 株式会社成和化成 | 化粧品基材および該化粧品基材を含有する毛髪用化粧品、美白剤 |
LV15485B (lv) * | 2018-09-13 | 2020-06-20 | Latvijas Organiskās Sintēzes Institūts | Selenofēnhromenonu hidroksāmskābes, to izgatavošana un izmantošana angioģenēzes inhibīcijā |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU68901A1 (de) | 1973-11-30 | 1975-08-20 | ||
US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
DE69737605T2 (de) * | 1996-01-23 | 2008-04-03 | Shionogi & Co., Ltd. | Sulfonierte aminosäurederivate und metalloproteinase-inhibitoren, die diese enthalten |
JPH10265452A (ja) * | 1996-05-24 | 1998-10-06 | Ono Pharmaceut Co Ltd | フェニルスルホンアミド誘導体 |
CA2268418A1 (en) * | 1996-10-22 | 1998-04-30 | Pharmacia & Upjohn Company | .alpha.-amino sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors |
EA002594B1 (ru) * | 1997-02-03 | 2002-06-27 | Пфайзер Продактс Инк. | Производные арилсульфониламиногидроксамовой кислоты |
AU7294098A (en) | 1997-05-09 | 1998-11-27 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
KR100352316B1 (ko) * | 1997-07-31 | 2002-09-12 | 더 프록터 앤드 갬블 캄파니 | 메탈로프로테아제억제제로서사용되는술포닐아미노치환히드록삼산유도체 |
JPH11199512A (ja) | 1997-10-24 | 1999-07-27 | Pfizer Prod Inc | 変形性関節症および他のmmp媒介疾患の治療のためのmmp−13選択的阻害剤の使用 |
PA8469601A1 (es) * | 1998-04-10 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para alquilar sulfonamidas impedidas estericamente |
HUP0104658A3 (en) * | 1998-12-22 | 2005-12-28 | Hoffmann La Roche | Sulfonamide hydroxamates |
EP1139998B8 (de) | 1998-12-28 | 2006-01-11 | Südzucker AG Mannheim/Ochsenfurt | Verwendung von wasserunlöslichen linearen poly-alpha-glucan als uv-filter |
FR2799964B1 (fr) | 1999-10-22 | 2002-07-26 | Oreal | Emulsions contenant au moins un filtre uv organique insoluble et un polymere associatif |
ATE330581T1 (de) | 2000-05-10 | 2006-07-15 | Ciba Sc Holding Ag | Silylierte verbindungen als vorläufer für selbstbräunungs zusammensetzngen |
GB0028161D0 (en) | 2000-11-17 | 2001-01-03 | Natural Environment Res | Personal care compositions |
FR2827860B1 (fr) * | 2001-07-24 | 2004-12-10 | Servier Lab | Nouveau procede de synthese de derives de l'acide (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxyline et application a la synthese du perindopril |
DE10155200A1 (de) | 2001-11-12 | 2003-05-28 | Skinlab Gmbh | Verwendung von Cholesterin, cholesterinhaltigen Substanzen oder von den Cholesteringehalt erhöhenden Substanzen in kosmetischen und dermatologischen Zubereitungen zum Zwecke der UV-Protektion |
DE10155769A1 (de) | 2001-11-14 | 2003-05-22 | Cognis Deutschland Gmbh | Kosmetische und/oder pharmazeutische Emulsionen |
US7504425B2 (en) * | 2002-05-29 | 2009-03-17 | Merck & Co., Inc. | Compounds useful in the treatment of anthrax and inhibiting lethal factor |
-
2004
- 2004-08-03 IT IT000174A patent/ITFI20040174A1/it unknown
-
2005
- 2005-07-29 US US11/659,431 patent/US7772430B2/en not_active Expired - Fee Related
- 2005-07-29 AU AU2005268765A patent/AU2005268765B2/en not_active Ceased
- 2005-07-29 CA CA002580235A patent/CA2580235A1/en not_active Abandoned
- 2005-07-29 RU RU2007107872/04A patent/RU2406721C2/ru not_active IP Right Cessation
- 2005-07-29 EP EP10188800A patent/EP2308837A3/de not_active Withdrawn
- 2005-07-29 EP EP05769876A patent/EP1781601B1/de active Active
- 2005-07-29 JP JP2007524333A patent/JP2008509108A/ja active Pending
- 2005-07-29 DE DE602005025495T patent/DE602005025495D1/de active Active
- 2005-07-29 WO PCT/EP2005/053722 patent/WO2006013193A2/en active Search and Examination
- 2005-07-29 CN CNA2005800336789A patent/CN101076514A/zh active Pending
- 2005-07-29 AT AT05769876T patent/ATE492530T1/de not_active IP Right Cessation
- 2005-07-29 MX MX2007001269A patent/MX2007001269A/es not_active Application Discontinuation
- 2005-07-29 BR BRPI0514030-7A patent/BRPI0514030A/pt not_active IP Right Cessation
-
2007
- 2007-02-28 ZA ZA200701798A patent/ZA200701798B/xx unknown
-
2010
- 2010-08-04 US US12/849,981 patent/US20100298439A1/en not_active Abandoned
- 2010-08-31 RU RU2010136061/04A patent/RU2010136061A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2008509108A (ja) | 2008-03-27 |
EP2308837A2 (de) | 2011-04-13 |
US20080249032A1 (en) | 2008-10-09 |
RU2010136061A (ru) | 2012-03-10 |
CA2580235A1 (en) | 2006-02-09 |
AU2005268765B2 (en) | 2011-08-04 |
US20100298439A1 (en) | 2010-11-25 |
MX2007001269A (es) | 2007-07-16 |
WO2006013193A8 (en) | 2010-07-29 |
RU2406721C2 (ru) | 2010-12-20 |
ZA200701798B (en) | 2008-08-27 |
AU2005268765A1 (en) | 2006-02-09 |
WO2006013193A3 (en) | 2006-08-31 |
EP1781601A2 (de) | 2007-05-09 |
CN101076514A (zh) | 2007-11-21 |
WO2006013193A2 (en) | 2006-02-09 |
US7772430B2 (en) | 2010-08-10 |
EP2308837A3 (de) | 2011-04-20 |
ATE492530T1 (de) | 2011-01-15 |
BRPI0514030A (pt) | 2008-05-27 |
EP1781601B1 (de) | 2010-12-22 |
ITFI20040174A1 (it) | 2004-11-03 |
RU2007107872A (ru) | 2008-09-10 |
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