DE602004032465D1 - Referenzstandard zur charakterisierung von rosuvastatin - Google Patents

Referenzstandard zur charakterisierung von rosuvastatin

Info

Publication number
DE602004032465D1
DE602004032465D1 DE602004032465T DE602004032465T DE602004032465D1 DE 602004032465 D1 DE602004032465 D1 DE 602004032465D1 DE 602004032465 T DE602004032465 T DE 602004032465T DE 602004032465 T DE602004032465 T DE 602004032465T DE 602004032465 D1 DE602004032465 D1 DE 602004032465D1
Authority
DE
Germany
Prior art keywords
rosuvastatin
characterization
reference standard
standard
analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004032465T
Other languages
English (en)
Inventor
Nina Finkelstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34676616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602004032465(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of DE602004032465D1 publication Critical patent/DE602004032465D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
DE602004032465T 2003-12-02 2004-12-02 Referenzstandard zur charakterisierung von rosuvastatin Active DE602004032465D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52644903P 2003-12-02 2003-12-02
PCT/US2004/040329 WO2005056534A1 (en) 2003-12-02 2004-12-02 Reference standard for characterization of rosuvastatin

Publications (1)

Publication Number Publication Date
DE602004032465D1 true DE602004032465D1 (de) 2011-06-09

Family

ID=34676616

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004032465T Active DE602004032465D1 (de) 2003-12-02 2004-12-02 Referenzstandard zur charakterisierung von rosuvastatin

Country Status (13)

Country Link
US (6) US7244844B2 (de)
EP (1) EP1689723B1 (de)
JP (1) JP4733047B2 (de)
KR (1) KR100887264B1 (de)
CN (1) CN1894221B (de)
AT (1) ATE507209T1 (de)
CA (1) CA2546894C (de)
DE (1) DE602004032465D1 (de)
ES (1) ES2364143T3 (de)
IL (1) IL175511A (de)
PT (1) PT1689723E (de)
TW (1) TWI351958B (de)
WO (1) WO2005056534A1 (de)

Families Citing this family (15)

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GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
US7244844B2 (en) * 2003-12-02 2007-07-17 Teva Pharmaceutical Industries Ltd. Reference standard for characterization of rosuvastatin
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
KR101020024B1 (ko) 2005-02-22 2011-03-09 테바 파마슈티컬 인더스트리즈 리미티드 로수바스타틴 알킬에테르를 함유하지 않는 로수바스타틴 및이의 염 및 이의 제조 방법
AU2006329006B2 (en) * 2005-12-20 2013-02-28 Lek Pharmaceuticals D.D. Pharmaceutical composition comprising (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid
MX2008014552A (es) * 2007-03-13 2009-03-09 Teva Pharma Forma de triol de rosuvastatina.
EP2189456A1 (de) * 2008-11-14 2010-05-26 LEK Pharmaceuticals d.d. Neue Omeprazol-Verbindungen
EP2379506B1 (de) 2008-12-30 2015-09-02 ArQule, Inc. Substituierte 5,6-dihydro-6-phenylbenzo[f]-isochinolin-2-aminver-bindungen
CN103454352B (zh) * 2013-07-30 2015-07-15 广东先强药业有限公司 一种hplc法测定瑞舒伐他汀钙的含量及其有关物质的方法
CN103776939A (zh) * 2014-02-11 2014-05-07 润泽制药(苏州)有限公司 瑞舒伐他汀钙制剂有关物质的制备检测方法
CN108398501A (zh) * 2018-03-02 2018-08-14 海南通用三洋药业有限公司 一种检测瑞舒伐他汀钙有关物质的方法
CN109020902B (zh) * 2018-07-23 2020-06-02 唯智医药科技（北京）有限公司 一种瑞舒伐他汀钙杂质及其制备方法与用途
CN114280181A (zh) * 2021-12-23 2022-04-05 浙江海翔川南药业有限公司 一种瑞舒伐他汀中间体及其有关物质的检测方法

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US5177080A (en) 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
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JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
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KR20040026705A (ko) 2001-08-16 2004-03-31 테바 파마슈티컬 인더스트리즈 리미티드 스타틴의 칼슘 염 형태의 제조 방법
SK1402004A3 (sk) 2001-08-16 2005-01-03 Teva Pharmaceutical Industries Ltd. Spôsob prípravy vápenatých solí statinov
SE0103509D0 (sv) 2001-10-19 2001-10-19 Astrazeneca Ab Rosuvastatin in pre demented states
KR100511533B1 (ko) 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
AR039836A1 (es) 2002-05-21 2005-03-02 Ranbaxy Lab Ltd Proceso para la preparacion de un aldehido de pirimidina util para la preparacion de rosuvastatina
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
US7566782B2 (en) 2002-12-10 2009-07-28 Ranbaxy Laboratories Limited Process for the preparation of rosuvastatin
AU2003269478A1 (en) 2003-08-27 2005-03-16 Hetero Drugs Limited A novel process for amorphous rosuvastatin calcium
CN1886383A (zh) 2003-10-22 2006-12-27 兰贝克赛实验室有限公司 无定形罗苏伐他汀钙的制备方法
EP1601658A1 (de) 2003-11-24 2005-12-07 Teva Pharmaceutical Industries Limited Kristalline ammoniumsalze von rosuvastatin
US7244844B2 (en) * 2003-12-02 2007-07-17 Teva Pharmaceutical Industries Ltd. Reference standard for characterization of rosuvastatin
EP1797046A2 (de) 2004-09-27 2007-06-20 Ranbaxy Laboratories Limited Neue verfahren zur herstellung von amorphem rosuvastatincalcium und neue polymorphe form von rosuvastatinnatrium
JP2008528542A (ja) 2005-01-31 2008-07-31 チバ ホールディング インコーポレーテッド ロスバスタチンカルシウム塩の結晶形
EP1863773A1 (de) 2005-03-22 2007-12-12 Unichem Laboratories Limited Verfahren zur herstellung von rosuvastatin
US20080161560A1 (en) 2005-04-04 2008-07-03 Pandurang Balwant Deshpande Process for Preparation of Calcium Salt of Rosuvastatin
EP1915349B2 (de) 2005-06-24 2018-09-12 LEK Pharmaceuticals d.d. Verfahren zur herstellung von reinem amorphen rosuvastatin-calcium
WO2006136407A1 (en) 2005-06-24 2006-12-28 Lek Pharmaceuticals D.D. Process for preparing amorphous rosuvastatin calcium free of impurities
GB0514078D0 (en) 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process

Also Published As

Publication number Publication date
US7692008B2 (en) 2010-04-06
EP1689723A1 (de) 2006-08-16
US20090188305A1 (en) 2009-07-30
ES2364143T3 (es) 2011-08-25
JP4733047B2 (ja) 2011-07-27
KR100887264B1 (ko) 2009-03-06
US20050187234A1 (en) 2005-08-25
US7244844B2 (en) 2007-07-17
CA2546894A1 (en) 2005-06-23
TW200522959A (en) 2005-07-16
US20070249830A1 (en) 2007-10-25
CA2546894C (en) 2009-09-08
IL175511A (en) 2011-11-30
ATE507209T1 (de) 2011-05-15
CN1894221B (zh) 2012-08-08
PT1689723E (pt) 2011-07-06
US20070249831A1 (en) 2007-10-25
KR20060098396A (ko) 2006-09-18
EP1689723B1 (de) 2011-04-27
US7692010B2 (en) 2010-04-06
TWI351958B (en) 2011-11-11
US7692009B2 (en) 2010-04-06
US20070255059A1 (en) 2007-11-01
JP2007512354A (ja) 2007-05-17
US7741482B2 (en) 2010-06-22
IL175511A0 (en) 2006-09-05
US20070244321A1 (en) 2007-10-18
CN1894221A (zh) 2007-01-10
US8487097B2 (en) 2013-07-16
WO2005056534A1 (en) 2005-06-23

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