DE602004027770D1 - Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung - Google Patents

Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung

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Publication number
DE602004027770D1
DE602004027770D1 DE602004027770T DE602004027770T DE602004027770D1 DE 602004027770 D1 DE602004027770 D1 DE 602004027770D1 DE 602004027770 T DE602004027770 T DE 602004027770T DE 602004027770 T DE602004027770 T DE 602004027770T DE 602004027770 D1 DE602004027770 D1 DE 602004027770D1
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DE
Germany
Prior art keywords
orthogonal
compositions
trna
lysyl
aminoacyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE602004027770T
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English (en)
Inventor
Christopher J Anderson
Ning Wu
Stephen Santoro
Peter G Schultz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
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Scripps Research Institute
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Publication of DE602004027770D1 publication Critical patent/DE602004027770D1/de
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DE602004027770T 2003-07-07 2004-07-07 Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung Expired - Lifetime DE602004027770D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48545103P 2003-07-07 2003-07-07
US52881503P 2003-12-10 2003-12-10
US53714904P 2004-01-15 2004-01-15

Publications (1)

Publication Number Publication Date
DE602004027770D1 true DE602004027770D1 (de) 2010-07-29

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Family Applications (2)

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DE602004027770T Expired - Lifetime DE602004027770D1 (de) 2003-07-07 2004-07-07 Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung
DE602004011789T Expired - Lifetime DE602004011789T2 (de) 2003-07-07 2004-07-07 Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen

Family Applications After (1)

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DE602004011789T Expired - Lifetime DE602004011789T2 (de) 2003-07-07 2004-07-07 Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen

Country Status (14)

Country Link
US (4) US7638297B2 (de)
EP (2) EP1649004A4 (de)
JP (2) JP5192150B2 (de)
CN (1) CN101076598B (de)
AT (2) ATE471385T1 (de)
AU (1) AU2004267359B2 (de)
BR (1) BRPI0412272A (de)
CA (1) CA2531146A1 (de)
DE (2) DE602004027770D1 (de)
ES (1) ES2301099T3 (de)
MX (1) MXPA06000242A (de)
PT (2) PT1914314E (de)
SI (1) SI1666604T1 (de)
WO (1) WO2005019415A2 (de)

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